Good governance: Challenges and opportunities of Iran\'s context in achieving sustainable health development by Azam Raoofi, Hajar Haghighi, Khatere Khanjankhani, Masoomeh Ggholami, Amirhossein Takian

“…This study aims to provide a comprehensive definition of governance and its components, with a focus on health, and provide an overview of the challenges and opportunities of good governance and sustainable health development in Iran. Methods: This is a review study. We considered all published articles in Scopus and PubMed in Farsi and English, regardless of time limit until September 22, 2023. …”
Get full text

Inclusion in the cancer patient pathway among cancer patients with and without pre-existing mental or substance use disorders: a nationwide register-based study by Ina H. Heiberg, Lise Balteskard, Bjarne K. Jacobsen, Jørgen G. Bramness, Ragnar Nesvåg, Kjell Magne Tveit, Anne Høye

“…Methods This population-based registry study included incident cancer patients aged 21–79 between 2015 and 2018 (n = 65,328). …”
Get full text

A Comparative Investigation on Clinical Characteristics in Pediatric Obstructive Sleep Apnea Based on Two Distinct Guidelines by Ji T, Long T, Li X, Xu Z, Zhao J, Wang G, Wang H, Li H, Zhang F, Zheng L, Wang S, Ni X

“…Tingting Ji,1,* Ting Long,1,* Xiaodan Li,1,* Zhifei Xu,2 Jing Zhao,1 Guixiang Wang,1 Hua Wang,1 Hongbin Li,1 Fengzhen Zhang,1 Li Zheng,1 Shengcai Wang,1 Xin Ni1,3 1Department of Otolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China; 2Department of Respiratory Medicine, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China; 3Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck Surgery, Beijing Pediatric Research Institute, Beijing Children’s Hospital, Capital Medical University, National Center for Children’s Health, Beijing, 100045, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xin Ni, Email nixin@bch.com.cn; Shengcai Wang, Email wsc820329@163.comObjective: To investigate the differences in assessment of clinical characteristics between children with obstructive sleep apnea (OSA) diagnosed according to the 2007 and 2020 guidelines and those without OSA, together with the relationships between polysomnography (PSG) parameters and cognitive tests scores in preschool and school-aged children with OSA.Methods: Eighty children were totally recruited and divided into OSA and non-OSA groups based on two distinct guidelines, with further subclassification into preschool and school-aged subgroups. …”
Get full text

Development and validation of a nomogram prediction model for factors influencing 131I-refractory Graves’ hyperthyroidism by Kehua Liao, Xiaojuan Wei, Yan Chen, Dongyun Meng, Shaozhou Mo, Zeyong Sun, Fengyang Song, Lu Lu, Wentan Huang

“…ObjectiveTo examine the factors influencing 131I-refractory Graves’ disease (GD) hyperthyroidism in patients, develop a nomogram prediction model, and conduct its validation.MethodsA total of 272 hyperthyroidism patients who received initial 131I treatment at our hospital from January 2021 to January 2022 were randomly selected. …”
Get full text

Exome sequencing in Nigerian children with early‐onset epilepsy syndromes by Ibitayo Abigail Ademuwagun, Yagoub Adam, Solomon Oladapo Rotimi, Steffen Syrbe, Maximilian Radtke, Julia Hentschel, Johannes R. Lemke, Ezekiel Adebiyi

“…In this study, we employed ES to investigate the genetic basis of early‐onset epilepsy in 22 affected children from Nigeria. Methods The study involved sampling of patients diagnosed with early‐onset epilepsy syndromes at the Lagos State University Teaching Hospital (LASUTH) Neurology clinic. …”
Get full text

Banxia Gualou Xiebai Tang and Qishen Yiqi Dropping Pills Combined Therapy for Qi Deficiency, Phlegm, and Blood Stasis Syndrome in Post-PCI Coronary Heart Disease Patients by Fan M, Du L, Jiang W, Ding T, Yang X, Peng Z

“…Mingqiang Fan,1,* Li Du,1,* Wensheng Jiang,2 Tao Ding,1 Xiangxiang Yang,1 Zhengfei Peng1 1Department of Cardiovascular Medicine, Affiliated Hospital of Gansu Medical College, Pingliang, Gansu, 744000, People’s Republic of China; 2Department of Integrated Chinese and Western Medicine, Affiliated Hospital of Gansu Medical College, Pingliang, Gansu, 744000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingqiang Fan, Email fbz790@126.comObjective: To evaluate the effects of Banxia Gualou Xiebai Tang combined with Qishen Yiqi Dropping Pills on Qi deficiency, phlegm, and blood stasis syndrome in post-percutaneous coronary intervention (PCI) coronary heart disease (CHD) patients.Methods: A retrospective analysis was conducted on 100 post-PCI CHD patients with Qi deficiency, phlegm, and blood stasis syndrome treated from October 2022 to April 2024. …”
Get full text

Effect of Esketamine-Based Opioid-Sparing Anesthesia Protocol on the Quality of Early Recovery After Urological Surgery: A Randomized Clinical Trial by Qi Y, Li W, Ren Y, Sun J, Zhu Y, Wang L, Zhou M, Wang L

“…The present study explored the effect of the esketamine-based opioid-sparing anesthesia protocol on the quality of postoperative recovery in patients undergoing elective urological surgery.Patients and Methods: A randomized, double-blind, controlled clinical trial was adopted. …”
Get full text

Ant’s faunistic investigation (Hymenoptera:Formicidae) in Shiraz vicinity by Roshanak Torabi, Shahrokh Pashaei Rad, Mohammad Reza Shokri

“…Family Formicidae fauna in Iran is far from complete and yet 213 species of 32 genera and 4 subfamilies has been reported. Materials and methods: The present investigation deal with the study of ant fauna in Shiraz city. …”
Get full text

Wedelolactone Ameliorates Ischemic Stroke by Inhibiting Oxidative Damage and Ferroptosis via HIF-1α/SLC7A11/GPX4 Signaling by Tao X, Zhao M, Gao K, Zhang W, Xu D, Li W, Mu F, Lin R, Guo C, Li R, Wang J

“…However, the potential of Wel to improve ischemic stroke (IS) and the underlying mechanisms remain unclear.Methods: The middle cerebral artery occlusion and reperfusion (MCAO/R) and oxygen-glucose deprivation/reoxygenation (OGD/R) were established to evaluate the potential neuroprotective of Wel. …”
Get full text

Psychological rehabilitation of individuals with alcohol use disorder, drug addiction, gambling disorder, and codependency by Aidos Ibragim, Bakytgul Issatayeva, Kundyz Kuanzhanova, Almagul Mandykayeva, Aliya Mambetalina

“…Future policy initiatives should prioritize the development of therapist training programs and the implementation of evidence-based treatment methods. Moreover, the results emphasize the necessity for continuous post-treatment support to maintain long-term recovery and prevent relapse. …”
Get full text

Melatonin Activates KEAP1/NRF2/PTGS2 Pathway to Attenuate Hyperoxia-Driven Ferroptosis in Bronchopulmonary Dysplasia by Deng X, Xie A, Ye D, Ma Y, Bao Z, Xie Q, Luo Z, Wang R, Li H, Yu R

“…This study aimed to test the hypothesis that melatonin mitigates hyperoxia-induced BPD by inhibiting ferroptosis in alveolar epithelial cells, specifically through modulation of the KEAP1/NRF2/PTGS2 signaling pathway.Methods: Hyperoxia-induced MLE-12 cells and neonatal mice were used to establish BPD models. …”
Get full text

Intralesional Bleomycin in Periungual Warts: A Prospective Randomised Controlled Study by Kallolinee Samal, Nibedita Dixit, Srigopal Mohanty, Debjit Kar, Siddhartha Dash, Manoj Kumar Nayak

“…Aim: To study the efficacy and safety of Intralesional (IL) bleomycin in treating PW. Materials and Methods: A prospective randomised controlled study was conducted at the Department of Dermatology, SCB Medical College and Hospital, Odisha, India, from September 2019 to August 2020. …”
Get full text

Associations of Leukocyte-Derived Chemotaxin-2 (LECT2) with Insulin Resistance and Metabolic Syndrome in Type 2 Diabetes: A Cross-Sectional Study by Sha Y, Lu J, Jin R, Li L, Zhang M

“…The results could offer fresh perspectives on the diagnosis and therapeutic strategies for T2D and associated metabolic disorders.Methods: A cross-sectional study was conducted on 148 T2D patients, including 90 with MetS and 58 without MetS. …”
Get full text

Comparative Analysis of Short-Term Outcomes in Thoracoscopic Minimally Invasive Versus Traditional Mitral Valve Replacement: Randomized Clinical Trial Study by Yusuf Shieba, Abd Elhalim Shalaby, Tamer Elbanna, Mohamed-Adel Elgamal, Ahmed El-minshawy

“…Objective: The aim of this research is to investigate the short-term outcomes of thoracoscopic minimally invasive mitral valve replacement in comparison with the conventional technique. Subjects and Methods: This study included 100 patients with isolated mitral valve disease, who were randomly divided into two equal groups. …”
Get full text

Stakeholders’ Perceptions of the Peer-to-Peer Energy Trading Model Using Blockchain Technology in Indonesia by Faisal Yusuf, Riri Fitri Sari, Purnomo Yusgiantoro, Tri Edhi Budhi Soesilo

“…The results of filling out the questionnaire were analyzed using four methods: IFE/EFE matrix; IE matrix; SWOT matrix; and SPACE matrix to assess the results and their suitability to each other. …”
Get full text

Effect of combination antihypertensive therapy, including renin-angiotensin-aldosterone system inhibitors, on oxidative stress and arterial remodeling in hypertensive patients with... by Z. M. Akhilgova, A. P. Roitman, N. G. Rakova, A. V. Bugrov, E. A. Pavlovskaya, M. S. Zastrozhin, A. G. Avtandilov

“…To study the effect of triple combination therapy on oxidative stress and arterial remodeling in hypertensive patients with heart failure with preserved ejection fraction (HFpEF).Material and methods. The study involved 76 people with diagnosed HFpEF. …”
Get full text

Copper-Based Nanoparticles for Effective Treatment Against Sepsis-Induced Lung Injury in Mice Model by Li JM, Zhang L, Pei SL, Guo L, Shen HL, He J, Guo YY, Zhang WQ, Lin F

“…In this study, a novel class of ultrasmall nanoparticles (Cu4.5O USNPs) was developed to address sepsis-induced lung injury (SILI).Methods: The synthesized nanoparticles were thoroughly characterized to assess their properties. …”
Get full text

Non-Pharmaceutical Interventions on COVID-19 in Workers and Residents of Nursing Homes in Geneva: A Mixed Qualitative and Quantitative Study by Lakshmi Krishna Menon, Ania Wisniak, Simon Regard, Silvia Stringhini, Idris Guessous, Jean-François Balavoine, Omar Kherad, The SEROCoV-WORK + Study Group

“…Incident rate ratios (IRRs) were the calculated levels of NPI restrictiveness. Methods: We used a mixed methodology to identify factors that might have affected COVID-19 expansion in nursing homes in the canton of Geneva, Switzerland. …”
Get full text

Predicting Superaverage Length of Stay in COPD Patients with Hypercapnic Respiratory Failure Using Machine Learning by Zuo B, Jin L, Sun Z, Hu H, Yin Y, Yang S, Liu Z

“…This model is capable of predicting in advance whether an inpatient’s length of stay will exceed the average duration, thereby enhancing its clinical application and utility.Methods: The study included 568 COPD patients with hypercapnic respiratory failure, 426 inpatients from the Department of Respiratory and Critical Care Medicine of Yancheng First People’s Hospital in the modeling group and 142 inpatients from the Department of Respiratory and Critical Care Medicine of Jiangsu Provincial People’s Hospital in the external validation group. …”
Get full text

In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…The high porosity of biomaterials induces more M2 macrophages, while the natural compound kaempferol inhibits the expression of matrix metalloproteinase 9 (MMP9) and thus inhibits the associated inflammatory and immunological responses.Methods: portable electrospinning dressings (PEDs) were prepared from the spinning solution using a portable electrospinning device. …”
Get full text