Low-Density Lipoprotein Cholesterol as a Protective Factor in COPD and Implications for Statin Therapy: A Multi-Omics Genetic Epidemiology Study by Du T, Cao J, Dai Z, Xie X, Zhang G, Li Y, Chen B, Xu T, Feng J

“…This study aimed to explore the association between low-density lipoprotein cholesterol (LDL-C) and COPD, as well as the impact of statin drugs on the progression of COPD.Methods: Employing an integrated approach that encompasses observational studies, genetic epidemiology, and molecular biology, this research investigated the link between LDL-C and COPD using clinical survey data, genome-wide association study (GWAS) data, and transcriptomic data. …”
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The Role of Pyroptosis‐Related Gene Signature and Immune Infiltration in Juvenile Dermatomyositis by Qiao W, Zhu C, Huang D, Liu Y, Wang Z, Zhu T, Song Q, Yang X, Wang Y, Wang Y

“…Building upon previous research on the immunological and inflammatory aspects of JDM, this study aims to investigate the role of pyroptosis in the pathogenesis of JDM using a comprehensive bioinformatics approach.Methods: Two microarray datasets (GSE3307 and GSE11971) were obtained from the Gene Expression Omnibus database, and a list of 62 pyroptosis-related genes was compiled. …”
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Validation of Senescence of the Role of ATM/P53 Pathway in Myocardial Senescence in Mice with Sepsis by Yan Z, Shi X, Ding R, Xia F, Du Y, Wang X, Peng Q

“…This study aimed to investigate gene expression changes related to myocardial aging in sepsis.Methods: Transcriptomic datasets (GSE79962 and GSE141864) were analyzed to identify senescence-related genes (SRGs) by intersecting differentially expressed genes (DEGs) with the CellAge database. …”
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Decomposing socioeconomic differences in self-rated health and healthcare expenditure by chronic conditions and social determinants by Iris Meulman, Tessa Jansen, Ellen Uiters, Mariëlle Cloin, Johan Polder, Niek Stadhouders

“…This study identifies which chronic conditions and social determinants contribute most to socioeconomic differences in self-rated health and healthcare expenditure. Methods Registry and survey data combining 3 socioeconomic indicators (income, education, and financial welfare), 26 social determinants, 20 chronic conditions, age, sex, self-rated health, and healthcare expenditure for 135,183 Dutch individuals aged 25–65, were linked at individual level. …”
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A Bibliometric Analysis of the WoSCC Literature on the Use of Selective Serotonin Reuptake Inhibitors as Antidepressants by Li J, Fei X, Wang S, Xu Z, Xu F, Wang J, Gao Y, Hu Y

“…Therefore, we conducted a bibliometric analysis to explore the research patterns surrounding SSRIs for depression, aiming to gain a deeper understanding of their development and impact.Methods: Publications about the use of SSRIs for the treatment of depression were identified in the Web of Science Core Collection. …”
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Experiences of Individually Tailored Internet-Based Cognitive Behavioral Therapy During the COVID-19 Pandemic: Qualitative Interview Study by Victoria Aminoff, Matilda Baltius, Emelie Lundström, Matilda Berg, Gerhard Andersson, Mikael Ludvigsson

“…ObjectiveThis qualitative study aimed to investigate the experiences of participants undergoing individually tailored ICBT with weekly therapist support during the COVID-19 pandemic. MethodsWe approached trial participants who had received ICBT for psychological symptoms related to the COVID-19 pandemic during the summer of 2020. …”
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Clinical and Molecular Insights Into Anti-MDA5 Antibody-Positive Dermatomyositis: A Single-Center Retrospective and Transcriptomic Study by Ren Y, Wu T, Shi W

“…Yunli Ren,1,* Tianqi Wu,2,* Weiwei Shi3,4 1Department of Rheumatology and Immunology, Affiliated Hospital 2 of Nantong University, Nantong, People’s Republic of China; 2School of Medicine, Nantong University, Nantong, People’s Republic of China; 3Department of Dermatology, Affiliated Hospital 2 of Nantong University, Nantong, People’s Republic of China; 4Department of Dermatology, The Third Affiliated Hospital of Soochow University, Changzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Weiwei Shi, Department of Dermatology, Affiliated Hospital 2 of Nantong University, No. 666,Shengli Road, Nantong, 226000, People’s Republic of China, Email youzhi_gg@126.comObjective: To comprehensively characterize clinical features, diagnostic challenges, and prognostic biomarkers of anti-MDA5 antibody-positive dermatomyositis (MDA5-DM), incorporating transcriptomic analysis to elucidate underlying molecular mechanisms.Methods: We conducted a retrospective analysis of 29 MDA5-DM patients, collecting detailed clinical and laboratory data. …”
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The Radiosensitizing Effect of Tumor-Derived Microparticles Co-Loaded with Sorafenib and Gold Nanoparticles on Hepatocellular Carcinoma by Yu L, Liu J, Fan Y, Hu X, Zeng X, Luo S, Chen P

“…In this study, we introduce a novel approach for treating HCC using tumor cell-derived microparticles (MPs) co-loaded with sorafenib and gold nanoparticles (AuNP) in combination with radiotherapy.Methods: MPSF@AuNP was prepared by co-incubating AuNP with sorafenib, and was evaluated using dynamic light scattering (DLS), transmission electron microscopy (TEM), ultraviolet-visible spectrophotometry (UV-Vis), inductively coupled plasma optical emission spectrometry (ICP-OES), high-performance liquid chromatography (HPLC), and SDS-PAGE electrophoresis. …”
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Polyallylamine Hydrochloride-Modified Bovine Serum Albumin Nanoparticles Loaded with α-Solanine for Chemotherapy of Pancreatic Cancer by Wen Z, Luo S, Liu J, Huang Y, Chen G, Cai H

“…To address these issues, this study developed a nanoparticle delivery system (PBSO NPs) using bovine serum albumin as a carrier, with polyallylamine hydrochloride surface modification to enhance α-Sol delivery.Methods: PBSO NPs were characterized using transmission electron microscopy, dynamic light scattering, nanoparticle size analyzers, and Fourier-transform infrared spectroscopy. …”
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Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening by Li W, Wen Y, Fan Y, Hu Z, Deng Z, Huang Q

“…Wenqiang Li,1,* Youli Wen,1,* Yuting Fan,2 Zefu Hu,3 Zhiping Deng,1 Qian Huang3 1Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, Sichuan Province, 643000, People’s Republic of China; 2Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan Province, 637000, People’s Republic of China; 3Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, Sichuan Province, 635000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qian Huang, Department of Respiratory and Critical Care Medicine, Dazhou Dachuan District People’s Hospital (Dazhou Third People’s Hospital), Dazhou, 635000, Sichuan Province, People’s Republic of China, Tel +8615196767955, Email hq15196767955@163.com Zhiping Deng, Department of Respiratory and Critical Care Medicine, Zigong First People’s Hospital, Zigong, 643000, Sichuan Province, People’s Republic of China, Tel +8613608158051, Email zgsdzp1016@163.comPurpose: This study aims to investigate the association between the Life’s Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults.Patients and Methods: We screened the NHANES database for data from 2007– 2018. …”
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Self-Esteem and College Students’ Online Impulse Buying: The Independent and Interactive Moderating Role of Interdependent Self-Construal and Interpersonal Relationships by Guo T, Cai C, Xu Y, Huang M, Ni Y

“…Drawing on the theory of compensatory consumption, the current study aimed to examine the influence of self-esteem on college students’ online impulse buying and the independent and interactive moderating role of interdependent self-construal and interpersonal relationships.Patients and Methods: This study recruited 323 college students through random sampling and invited them to complete self-reported questionnaires measuring self-esteem, online impulse buying, interdependent self-construal, and interpersonal relationships. …”
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Health utility value of overactive bladder in Japanese older adults by Takashi Yoshioka, Kenji Omae, Satoshi Funada, Tetsuji Minami, Rei Goto

“…Abstract Objectives To determine the health utility values (HUVs) of overactive bladder (OAB), defined as urinary urgency, usually accompanied by urinary daytime or nocturnal frequency, with or without urinary incontinence, among adults aged ≥65 years and to assess the HUV decrements (disutilities) of OAB according to its severity. Methods This cross‐sectional Internet‐based study was conducted between 2 and 9 November 2023, with quota sampling with equal probability for each sex and age group (age 65–74 years and ≥75 years). …”
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The Effects of Hyperlipidemia on Postoperative Cognitive Dysfunction in Patients Undergoing Laparoscopic Gynecological Tumor Surgery by Shen H, Xiong Y, Liang Y, Liu Z, Guo L, Qin Y, He J, Lin F

“…However, the association between hyperlipidemia and POCD has not been well examined.Methods: A total of 98 patients were divided into hyperlipidemia group and normal lipid group based on blood lipid level. …”
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The Chinese-Adapted Jefferson Scale of Empathy - Medical Student Version for Assessing the Level of Empathy in Medical Students: A Study of the Reliability and Validity by Liu J, Lin T, Wu W, Duo H, Tian C

“…Jiong Liu,1,* Tonghao Lin,1,* Wencheng Wu,1 Hong Duo,2 Cuijiao Tian3 1Department of Radiation and Medical Oncology; Hubei Key Laboratory of Tumor Biological Behaviors; Hubei Province Cancer Clinical Study Center, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, People’s Republic of China; 2Zhongnan Hospital of Wuhan University, Institute of Hepatobiliary Diseases of Wuhan University, Transplant Center of Wuhan University, Hubei Key Laboratory of Medical Technology on Transplantation, Wuhan, 430071, People’s Republic of China; 3Teaching Affairs Office, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, 430071, People’s Republic of China*These authors contributed equally to this workCorrespondence: Cuijiao Tian, Email ZN000985@whu.edu.cnPurpose: To investigate the psychometric properties of the Chinese-Adapted Jefferson Scale of Empathy–Medical Student Version (JSE S-Version) and evaluate its applicability.Methods: The JSE S-Version was translated into Chinese and subsequently converted into an electronic questionnaire. …”
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USE IN THE TREATMENT OF BIOFLAVONOIDS PERIODONTAL DISEASE AND METABOLIC SYNDROME (EXPERIMENTAL RESEARCH) by O. А. Glazunov

“…Research aim: to study therapeutic and preventive effect of “Kvertulin” on a paradontium in rats with the metabolic syndrome. Materials and methods: an experimental metabolic syndrome was reproduced in white rats of Wistar line. …”
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Vitamin D Supplementation Selectively Affects Peripheral Lymphocyte Subsets in Infertile Women by Fan J, Zhao J, Zhang J, Chen Y, Bi X, Liu H, Liu J, Wang J, Wu X

“…Junmei Fan,1,* Jinghui Zhao,2,* Junkun Zhang,3 Yanhua Chen,1 Xingyu Bi,1 Huiping Liu,1 Junfen Liu,1 Jinbao Wang,1 Xueqing Wu1 1Department of Reproductive Medicine Center, Children’s Hospital of Shanxi and Women Health Center of Shanxi, Taiyuan, Shanxi, 030013, People’s Republic of China; 2Department of Pediatric and Adolescent Gynecology, Shenzhen Children’s Hospital, Shenzhen, Guangdong, 518000, People’s Republic of China; 3Department of Intensive Care Unit, Shanxi Bethune Hospital, The Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xueqing Wu, Department of Reproductive Medicine Center, Children’s Hospital of Shanxi and Women Health Center of Shanxi, 13th Xinmin North Street, Xinghualing District, Taiyuan, Shanxi, 030013, People’s Republic of China, Tel +86 351 3360725, Email xueqingw_wu95@163.comBackground: This study aimed to explore the effect of vitamin D supplementation on lymphocyte subsets in infertile women.Methods: The study involved a total of 247 patients who suffered recurrent embryo implantation failure (RIF) or recurrent spontaneous abortion (RSA) between January and December 2019 in the Reproductive Medicine Center of Children’s Hospital of Shanxi and Women Health Center of Shanxi. …”
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Investigation of sexual life and perceived spousal support in female recipients after kidney transplantation by Sennur Kula Sahin, Semra Bulbuloglu

“…To examine the perceived spousal support and sexual lives of female kidney recipients in the aim of this study. Methods: The study was conducted as a descriptive and cross-sectional research. 158 female kidney recipients were included in the study. …”
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Oxygen consumption, locomotory‐respiratory coupling and exercise‐induced pulmonary hemorrhage in horses during the Paso Fino gait by Shannon Massie, Renaud Léguillette, Warwick Bayly, Ray Sides, Angélica María Zuluaga‐Cabrera

“…Animals Eleven Paso Fino horses. Methods Prospective cohort study. Horses performed a standardized Paso Fino gait test across a wooden sounding board, simulating competition. …”
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Local Structural Indices Changes During Different Periods of Postherpetic Neuralgia: A Graphical Study in Structural Covariance Networks by Xiong J, Gu L, Jiang X, Kuang H, Lv H, Li Z, Xie Y, Luo Q, Jiang J

“…Jiaxin Xiong,1,* Lili Gu,2,* Xiaofeng Jiang,1 Hongmei Kuang,1 Huiting Lv,1 Zihan Li,1 Yangyang Xie,1 Qing Luo,1 Jian Jiang1 1Department of Radiology, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, People’s Republic of China; 2Department of Pain, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, Jiangxi, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian Jiang, Department of Radiology, The 1 st Affiliated Hospital, Jiangxi Medical College, Nanchang University, 17 Yongwaizheng Street, Nanchang, Jiangxi, 330006, People’s Republic of China, Tel +86 13576129759, Email ndyfy02072@ncu.edu.cnPurpose: In this study, we aim to explore the changes in network graph theory indices of structural covariance networks (SCNs) in PHN patients with different disease durations.Patients and Methods: High-resolution T1 magnetic resonance images were collected from 109 subjects. …”
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Pola komunikasi organisasi pada UKM UMY e-sport arena (UMY e-sport) by Idham Azhar Alfarizi, Pratiwi Wahyu Widiarti

“…This research is a qualitative descriptive study. The tada colletion methods used were observation, semi structured interview, and documentaion. …”
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