The Efficacy of CT-Guided Pulsed Radiofrequency of the Dorsal Root Ganglion Combined with Methylene Blue Sympathetic Injection on Herpes-Zoster Neuralgia: A Retrospective Study by Chen J, Deng J, Wang R, Ma L

“…This is the first report for thoracic or lumbar sympathetic nerve MB injection.Materials and Methods: 64 patients in study were divided into two groups: PRF combined with sympathetic nerves MB injection group (group A; n = 32,); PRF group (group B; n = 32). …”
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Articaine Needle - Free Anesthesia Vs Conventional Anesthesia in Root Canal Treatment of Irreversible Pulpitis in Permanent Teeth: A Prospective Study on Anesthetic Efficacy and Ef... by Qian S, Meng Z, Zhang H, Li K, Zhang F, Zhang S, Liu J, Zhou Z

“…Suhui Qian,1,* Ziying Meng,2,* Haiyan Zhang,1 Kaicheng Li,1 Fei Zhang,1 Sen Zhang,1 Jianfei Liu,1 Zhou Zhou1 1Department of Stomatology, Huaibei People’s Hospital, Huaibei, Anhui, People’s Republic of China; 2Stomatology Department of Suixi County Hospital, Huaibei, Anhui, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhou Zhou, Email Zz178685@163.comObjective: This study aimed to compare the anesthetic efficacy of articaine needle-free anesthesia with conventional lidocaine nerve block anesthesia for root canal treatment in permanent teeth with irreversible pulpitis.Methods: In this prospective clinical trial, 94 patients were randomly allocated to receive either articaine needle-free anesthesia (n=47) or lidocaine nerve block anesthesia (n=47). …”
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The impact of pulmonary hypertension on the risk of early graft dysfunction in related kidney transplantation by R. A. Ibadov, D. A. Chernov, S. Kh. Ibragimov, Z. T. Matkarimov

“…To study the prevalence of pulmonary hypertension among patients with end-stage renal disease and to determine its impact on the development of early renal graft dysfunction.Material and methods. The study was based on the analysis of treatment results in 650 patients who underwent kidney transplantation from a living related donor. …”
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Efficient system design of capacitive coupling wireless charging for low-power applications by Yasir M. Y. Ameen, Marwan H. Mohammed, Basil Mohammed Said

“…The methods used include LCLC and LCL compensation topologies resonate with the capacitive coupler and deliver high voltage to the charging pads. …”
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FAM105B Promotes Hepatocellular Carcinoma Progression and Metastasis by Activating the PI3K/AKT/MTOR Signaling Pathway and Inducing Epithelial-Mesenchymal Transition by Yang LL, Chen X, Tang ST, Huang KT, Ye GY, Wang JL

“…However, its role in HCC is not well understood.Methods: FAM105B expression in HCC patients was validated using public clinical datasets. …”
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Amelioration of Inflammation and Metabolic Blockage in GALC Deficient Mice After Enzyme Replacement Therapy via Extracellular Vesicles by Zelada D, Saldivia N, Samano S, George D, Chaudhari K, Nguyen D, Simchuk D, Van Breemen RB, Givogri MI

“…Early intervention is critical to mitigate disease progression and limit neurological injury.Methods: To assess the therapeutic potential of early enzyme replacement therapy (ERT), HeLa cells were genetically engineered to overexpress GALC, and extracellular vesicles (EVs) containing GALC were isolated. …”
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Anti-Inflammatory Regulatory Role of Signal Transducer and Activator of Transcription 3 Phosphorylation in Regulating Hypersensitivity Responses to Echinococcus granulosus Hydatid... by Li SS, Zhou JR, Wang CS, Wang JL, Li YQ, Kulaixi X, Cao LW, Batesurong B, Ye JR

“…Shan-Shan Li,1,2,* Jing-Ru Zhou,3,* Chun-Sheng Wang,1,2 Jia-Ling Wang,1 Yu-Qian Li,1,2 Xilizati Kulaixi,1 Li-Wei Cao,1,2 Bayina Batesurong,1,2 Jian-Rong Ye1 1Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China; 2The First Clinical Medical College of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China; 3Department of Anesthesiology, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang Uygur Autonomous Region, 830063, People’s Republic of China*These authors contributed equally to this workCorrespondence: Jian-Rong Ye, Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, No. 137, Liyushan South Road, Urumqi, Xinjiang Uygur Autonomous Region, 830054, People’s Republic of China, Tel +86 18999938777, Email ywjianrongym@126.comObjective: This study aims to investigate the anti-inflammatory regulatory function of signal transducer and activator of transcription 3 (STAT3) phosphorylation in hypersensitivity responses triggered by Echinococcus granulosus hydatid cyst fluid through in vitro RBL-2H3 cell culture.Methods: RBL-2H3 cells were cultured in vitro and sensitized with immunoglobulin E (IgE), followed by intervention with STAT3 inhibitors Stattic and JSI-124. …”
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Prescription of essential medication during the final hospitalization of patients with heart failure or cancer by Valentina González-Jaramillo, Monika Hagemann, Lukas Hunziker, Maud Maessen, Steffen Eychmüller

“…Aim To assess the prescription frequency of each of the four medication types during the final hospitalization of patients with HF and compare it with the prescription frequency in patients with cancer (CA), considering both PC + and PC- patients in each disease group. Methods A retrospective cohort study included all patients dying in a tertiary hospital between 2016 and 2022. …”
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Indicators Of Morbidity And Mortality From Diseases of the Digestive System in the Krasnodar Krai and the Quality of Medical Care for Gastroenterological Patients by N. V. Korochanskaya, V. M. Durleshter, O. V. Kovalevskaya, S. N. Serikova, K. I. Popandopulo

“…To analyse the dynamics of morbidity and mortality from diseases of the digestive system, as well as the quality of medical care for gastroenterological patients in the Krasnodar Krai.Materials and methods. The analysis was carried out according to C 51 “Distribution of deaths by gender, age groups and causes of death” form of the Territorial Authority of the Federal State Statistics Service for the Krasnodar Krai for the period from 2006 to 2018, as well as on the basis of the “Demography” block database of the Parus software of the healthcare management system of the Krasnodar Krai for 6 months of 2019. 1341 medical records of patients receiving outpatient medical care and the medical records of people who had died from digestive diseases in 2017-2019 were reviewed.Results. …”
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Elucidating Molecule-Crosstalk of Neutrophil Extracellular Traps Between Cardiovascular Disease and Psoriasis: Insights Into Mendelian Randomization, Single-Cell RNA Analysis, Shar... by Jin X, Zhang Y, Qin G, Fang X, Zhang X, Sun J, Zhou M, Tong X, Xue Y, Yang H, Tian W

“…Neutrophil extracellular traps (NETs) are implicated in both conditions, but the mechanisms remain unclear.Methods: We integrated bulk and single-cell RNA sequencing, mendelian randomization, immune microenvironment analysis, and molecular docking to explore the molecular interactions between LVH and PSO, focusing on NET-related pathways. …”
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Impact of preoperative mild cognitive impairment on cerebrovascular events and cognitive status in patients undergoing coronary artery bypass grafting: data from 5-year follow-up by I. D. Syrova, O. A. Trubnikova, I. V. Tarasova, O. V. Maleva, S. E. Semenov, I. S. Lozhkin, O. L. Barbarash

“…To assess the incidence of cerebrovascular events and cognitive status in the long-term period after coronary artery bypass grafting (CABG) in patients with and without preoperative mild cognitive impairment (MCI).Material and methods. This prospective study involved 115 patients aged 45 to 69 years, who were admitted to the hospital for elective on-pump CABG. …”
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Long-Term Administration of Anthraquinone Rhein on Induction of Constipation in Sprague-Dawley Rats via SCF/c-Kit Signaling Pathways by Bo Zhang, Mingdong Huo, Zhicheng Chen, Feng Gao, Yan Liu, Xingxin Zhou

“…Herein, we aimed to investigate the long-term stimulation of rhein on induction of constipation in rats and its underlying mechanisms. Materials and Methods. After establishing rat models of constipation, the rats were randomly divided into two equal subgroups and administered daily with normal saline (model control group) or 10 ml/kg PEG4,000 (PEG-treated group). …”
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Profile of the geriatric patient hospitalised at Universitas Hospital, South Africa by Anna M. van Staden, Dirk J.V. Weich

“…Thus, there is an urgent need for profiles of elderly patients in order for adequate training to be implemented and for beds and equipment to be ready when needed. Methods: A retrospective study was undertaken of all data available from a clinical audit done at Universitas Hospital's Geriatric Unit. …”
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Preoperative chronic opiate use associated with a worse joint-specific function and quality of life before and after total hip and knee arthroplasty by Eliott S. Martinson, Nick D. Clement, Deborah J. MacDonald, Chloe E. H. Scott, Colin R. Howie

“…Aims: The aim of this study was to assess whether chronic pre-arthroplasty use of strong opiates impacted the pre- and postoperative joint-specific function, quality of life (QoL), pain scores, and satisfaction in those undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). Methods: This prospective study assessed 1,487 patients (THA n = 729; TKA n = 758). …”
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Novel Obstetric Air Cushion for the Prevention of Hypotension During Spinal Anesthesia for Cesarean Section: A Randomized Controlled Clinical Trial by Dong Y, Cao WW, Weng H, Liu R, Huang DD

“…We assessed the effect of a novel obstetric air cushion pretreatment on the incidence of hypotension after spinal anesthesia.Patients and Methods: Eighty parturients were randomly assigned to the air cushion or blank control group (Group A or B, respectively). …”
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Prognostic Value of the Triglyceride-Glucose Index Combined with Non-HDL-C/HDL-C Ratio for Predicting Coronary Microvascular Dysfunction in ACS Patients Post-PCI by Hang S, Tang N, Li K, Zhang Q, Hao J, Zhang Y, Qi C

“…This study aimed to evaluate the combined predictive value of the triglyceride-glucose index (TyG) and non-HDL-C/HDL-C ratio (NHHR) for CMD in ACS patients post-PCI.Methods: A retrospective analysis of 542 ACS patients undergoing PCI (2021– 2023) was conducted. …”
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Impact of root canal shaping using TruNatomy on postoperative pain and operative torque generation: a randomized clinical trial by Tarek Ali Al-Mosalmy, Heba Maged El-Far, Madiha Mahmoud Gomaa, Dina Ahmed Morsy

“…Aim To compare the effect of canal shaping using TruNatomy (TN) rotary system to RaCe (RC) rotary system on post-operative pain in necrotic maxillary bi-rooted premolars, while simultaneously inspecting the real-time dynamic forces produced during instrumentation. Methods In this parallel group superiority trial, following power calculation, 40 patients diagnosed with pulp necrosis in asymptomatic bi-rooted maxillary premolars were recruited and randomly allocated into two equal groups (n = 20) according to the instrumentation system used. …”
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PANoptosis-Relevant Subgroups Predicts Prognosis and Characterizes the Tumour Microenvironment in Ovarian Cancer by Chen Y, Deng Z, Chen J, Lin J, Zou J, Li S, Sun Y

“…However, its prognostic relevance in OC remains unclear.Methods: Utilizing data from The Cancer Genome Atlas (TCGA), we analyzed transcriptomic and clinical signatures of OC patients. …”
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Health Literacy, Label Comprehension, and Consumer Perceptions of Quasi-Drug Information Among Korean Adults: A Cross-Sectional Study by Ko Y, Kim HJ, Lee SM

“…This study aimed to evaluate HL and its impact on comprehending quasi-drug labels, assess consumer perceptions of key label elements and their perceived importance, and provide actionable recommendations for improving label design and health communication.Methods: An online cross-sectional survey of 500 Korean adults (aged 20– 69) was conducted in September 2023 using proportionate stratified sampling based on the 2020 Korean Census. …”
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Model-Informed Precision Dosing of Remimazolam in General Anesthesia Patients by Chen Y, Zhang ZJ, Zhang XF, Peng Y, Jiao Z, Wu JX

“…Yueting Chen,1,* Zuo-Jing Zhang,2,* Xiao-Feng Zhang,2 Yuan Peng,2 Zheng Jiao,1,* Jing-Xiang Wu2,* 1Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zheng Jiao, Department of Pharmacy, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200030, People’s Republic of China, Email jiaozhen@online.sh.cn Jing-Xiang Wu, Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Xuhui District, Shanghai, 200030, People’s Republic of China, Tel +86 021-22200000-3302, Fax +86 021-32260806, Email wjx1132@163.comPurpose: This study aimed to characterize the pharmacokinetics/pharmacodynamics (PK/PD) of remimazolam in patients under general anesthesia using a population analysis and to develop a web-based dashboard tool that directly displays the optimal dosing regimen for general anesthesia.Patients and Methods: A total of 20 patients received remimazolam for general anesthesia, during which intensive arterial blood samples and bispectral index (BIS) values were collected. …”
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