Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis by Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C

“…The aim of this study was to explore the pharmacological mechanism of Corilagin.Methods: This study utilized gas chromatography-mass spectrometry (GC-MS) to analyze central target tissues, comprehensively exploring the pharmacological mechanism of Corilagin in mouse models. …”
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Evaluation of Iron Overload Between Age Groups Using Magnetic Resonance Imaging and Its Correlation with Iron Profile in Transfusion-dependent Thalassemia by Pustika Amalia Wahidiyat, Stephen Diah Iskandar, Damayanti Sekarsari

“…This study aimed to explore the degree of iron overload in various organs, iron deposition difference between children and adults, also its correlation with serum marker of iron overload. Methods: this was a cross-sectional study of TDT patients who had been evaluated by MRI T2* examination in Cipto Mangunkusumo Hospital from 2014 to 2018. …”
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A measure of the difference between test sets for generating controlled random tests by V. N. Yarmolik, V. V. Petrovskaya, I. Mrozek

“…The limitations of using the Hamming and Damerau – Levenshtein distances to obtain a measure of the difference between test sets are shown.Methods . Based on the characteristic of the interval used in the theory of the chain of successive events, a new measure of the difference between two symbolic test sets is determined. …”
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Analysis of Tumor and Tumor-Like Entities Tested on the Orthopaedic In-Training Examination From 2012 to 2023 by Sean Kelly, MD, Braden Goldberg, MD, Eli Bryk, MD, FAAOS, FAOA, FACS, Vincent Vigorita, MD

“…This study aims to describe such trends. Methods:. This study analyzed OITE questions from 2012 to 2023, focusing on tumors and tumor-like conditions of bone and soft tissue to guide resident preparation and core curriculum design. …”
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Symbiotic anti-oxidant, anti-glycation, and anti-inflammatory qualities of a combination of thiamine and niacin protected type-2 diabetic male rats against both macro and micro-vas... by Sina Mahdavifard, Hamid Reza Malekzadeh

“…Therefore, we aimed to study the impact of the combination of thiamine and niacin on hepatic NF-kβ signaling, metabolic profile, and Glo-I activity in male rats with type-2 diabetes (T2DM).Materials and Methods: Forty male rats were divided equally into five groups: control, diabetic, diabetic treated with thiamine (180 mg/l in drinking water), niacin (180 mg/l), and a combination of both. …”
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Combining Supervised and Reinforcement Learning to Build a Generic Defensive Cyber Agent by Muhammad Omer Farooq, Thomas Kunz

“…The framework demonstrates consistently improved performance over a range of existing methods, as validated through extensive empirical evaluation. …”
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User experience with pregnancy tracker mobile apps: Findings from comment-based qualitative study. by Md Alamgir Hossain, Janet Perkins, Md Tanvir Hasan, Sharon Low Bee Lian, Ribica Chowdhury, Md Tanzirul Alam, Anisuddin Ahmed, Mohammad Sohel Shomik, Shams El Arifeen, Ahmed Ehsanur Rahman, Aniqa Tasnim Hossain, M Shafiqur Rahman

“…<h4>Methods</h4>This study explored the dynamics between users' experiences and multifaceted dimensions of advanced features, high-quality materials and information, strict privacy policies, problem-solving abilities, and the usefulness of app features and contents. …”
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Periconception glycemic control and congenital anomalies in women with pregestational diabetes by Annie M Dude, Nevert Badreldin, Amanda Schieler, Lynn M Yee

“…Introduction To assess the relationship between periconception glycemic control and congenital anomalies in a contemporary, diverse population of women with pregestational diabetes.Research design and methods This is a retrospective cohort study of all pregnant women with pregestational diabetes at a single institution (2003–2017) in the USA. …”
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Institutional priorities and student engagement: a multi-stakeholder analysis of physical education in Israel by Ali Alayan, Ahmad Salhab, Paz Carmel, Ronit Ahdut HaCohen

“…This study investigates the perceptions of students, PE teachers, and school administrators in Israel regarding PE value, participation, and institutional support.MethodsA cross-sectional survey was conducted with 150 participants from six East Jerusalem secondary schools, including students (70%), PE teachers (20%), and administrators or other staff (10%). …”
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Psychiatrists’ experiences with the implementation of safewards and other quality improvement work: an explorative, qualitative interview study by Martin Lindow, Mårten J. Tyrberg, Veikko Pelto-Piri, Anna Björkdahl

“…This study aimed to identify key facilitators and barriers to psychiatrists’ engagement in implementing Safewards and other quality improvement work. Methods In this qualitative exploratory study, semi-structured interviews and inductive content analysis were utilized. …”
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Non-menstrual pelvic symptoms and women's quality of life: a cross-sectional observational study. by Marlon de Freitas Fonseca, Felipe Ventura Sessa, Claudio Peixoto Crispi, Nilton de Nadai Filho, Bruna Rafaela Santos de Oliveira, Rafael Ferreira Garcia, Claudio Peixoto Crispi

“…This study aimed to compare the relative burdens of 4 different non-menstrual pelvic symptoms on HQoLife: Deep dyspareunia (DDyspareunia), non-menstrual pelvic pain (NMPelvicPain), non-menstrual dyschezia (NMDyschezia) and non-menstrual dysuria (NMDysuria).<h4>Subjects and methods</h4>This is a pre-planned cross-sectional interdisciplinary retrospective observational study. …”
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Views on patient portal use for adolescents in mental health care - a qualitative study by Martine Stecher Hornum, Aslak Steinsbekk, Torunn Hatlen Nøst

“…The aim was therefore to explore the views on using patient portals for adolescents in mental health care among persons involved in and/or being affected by the introduction of a patient portal. Methods A qualitative study was conducted using individual semi-structured interviews with 14 persons who were healthcare providers in child and adolescent mental health care, young representatives from the user panel, or persons affiliated with an EHR-project introducing a patient portal. …”
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A Prospective Tumour Marker for Breast Cancer: YWHAB and Its Role in Promoting Oncogenic Phenotypes by Gopaul VL, Winstone L, Gatien BG, Nault BD, Maiti S, Opperman RM, Majumder M

“…The potential of YWHAB as a therapeutic target or biomarker for BRCA is investigated here.Methods: After YWHAB was knocked down with siRNA, BRCA cell lines were used for in vitro assays (proliferation, migration, epithelial-to-mesenchymal transition). …”
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Enhanced phoxim biodegradation by immobilizing Novosphingobium sp. RL4 on attapulgite-sodium alginate by Tong Peng, Tong Peng, Yining Huang, Tao Yang, Tao Yang, Yinquan Wang, Ling Jin

“…The immobilization of degrading strains on natural adsorbent materials is a common strategy to enhance the degradation of target compounds in the environment by the strains.MethodsA phoxim-degrading bacterial strain was isolated from the rhizosphere soil of rhubarb (Rheum palmatum L.), which had been exposed to long-term phoxim contamination. …”
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CLINICAL EFFICACY OF A GEL BASED ON BIO SUBSTANTIATION FROM THE PRODUCTS OF ANTLER MARAL BREEDING IN THE TREATMENT OF GINGIVITIS by Светлана Ивановна Токмакова, Юлия Васильевна Луницына, Ольга Владимировна Бондаренко, Вера Феопеновна Турецкова, Любовь Габдулбариевна Дворникова, Виктория Анатольевна Кузикова, Алёна Олеговна Шевякина

“…The aim of the research – to evaluate the clinical effectiveness of a dental gel based on dry maral blood in the complex treatment of gingivitis. Materials and methods. A prospective controlled clinical study was conducted with the participation of 42 volunteers with generalized chronic catarrhal gingivitis. …”
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Artificial Intelligence-Based Classification of Anatomical Sites in Esophagogastroduodenoscopy Images by Yuan P, Ma ZH, Yan Y, Li SJ, Wang J, Wu Q

“…This study aimed to evaluate the effectiveness of artificial intelligence in identifying gastric anatomy sites by analyzing esophagogastroduodenoscopy images.Methods: Using endoscopic images, we proposed a system called the Artificial Intelligence of Medicine (AIMED) through convolutional neural networks and MobileNetV3-large. …”
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The Relationship Between Intolerance of Uncertainty and Treatment Adherence: The Moderating Effect of Self-Compassion on the Chain Mediation Model by Shi X, Wang Y, Jia Q, Peng S, Liu X, Pei Y

“…Existing research indicates that intolerance of uncertainty is closely associated with patients’ follow-up compliance; however, further in-depth investigation into its influencing mechanisms and potential improvement strategies is required.Patients and Methods: This study conducted a questionnaire survey among 319 young and middle-aged patients newly diagnosed with pulmonary nodules, examining the moderating effect of self-compassion on follow-up compliance and investigating the chain intermediary role of negative interpretation bias and trust in linking intolerance of uncertainty to follow-up compliance.Results: The study found that women, urban residents, and patients over 50 years old demonstrated relatively higher follow-up compliance. …”
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Impact of a single non-sex-related stroke risk factor on atrial fibrillation and oral anticoagulant outcomes: a systematic review and meta-analysis by An De Sutter, Lies Lahousse, Stephane Steurbaut, Maxim Grymonprez

“…A critical appraisal of the role of OACs and the benefit–risk profile of non-vitamin K antagonist oral anticoagulants (NOACs) compared with vitamin K antagonists (VKAs) in this patient subgroup are needed.Methods and results This systematic review provides an overview of literature on the effectiveness and safety of OACs in AF patients with a single non-sex-related stroke risk factor after searching Medline and Embase. …”
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A voxel-based morphometric study of age- and sex-related changes in white matter volume in the normal aging brain by Liu H, Wang L, Geng Z, Zhu Q, Song Z, Chang R, Lv H

“…&amp;nbsp; Materials and methods: A total of 187 cognitively normal adults were divided into the young, middle, and old age-groups. …”
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Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22. by John D Kelly, Tim J Dudderidge, Alex Wollenschlaeger, Odu Okoturo, Keith Burling, Fiona Tulloch, Ian Halsall, Teresa Prevost, Andrew Toby Prevost, Joana C Vasconcelos, Wendy Robson, Hing Y Leung, Nikhil Vasdev, Robert S Pickard, Gareth H Williams, Kai Stoeber

“…Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22.<h4>Methods</h4>1677 consecutive patients under investigation for urinary tract malignancy were recruited to a prospective blinded observational study. …”
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