Metabolic consequences of erastin-induced ferroptosis in human ovarian cancer cells: an untargeted metabolomics study by Kaylie I. Kirkwood-Donelson, Alan K. Jarmusch, Carl D. Bortner, Bruce Alex Merrick, Birandra K. Sinha

“…Erastin (ER), a ferroptosis inducer, kills tumor cells by generating and accumulating reactive oxygen species (ROS) within the cell, resulting in an iron-dependent oxidative damage-mediated ferroptotic cell death.MethodsWe have utilized human ovarian cancer cell lines, OVCAR-8 and its adriamycin-selected, multi-drug resistance protein (MDR1)-expressing NCI/ADR-RES, both equally sensitive to ER, to identify metabolic biomarkers of ferroptosis.ResultsOur studies showed that ER treatment rapidly depleted cellular glutathione and cysteine and enhanced formation of ophthalamate (OPH) in both cells. …”
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Determinants of Hypovitaminosis D in Pregnant Women and Their Newborns in a Sunny Region by Roya Kelishadi, Faezeh Sharifi-Ghazvini, Parinaz Poursafa, Ferdous Mehrabian, Sanam Farajian, Hosseinali Yousefy, Mahsa Movahedian, Sanaz Sharifi-Ghazvini

“…This study aims to assess the factors associated with 25-hydroxy vitamin D (25(OH)D) levels in pregnant women and their newborns in a sunny region. Materials and Methods. This cross-sectional study was conducted in 2012 in Isfahan, Iran. …”
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ANALYSIS OF PROBLEM AREAS OF DENTAL CARE IN THE ALTAI TERRITORY ACCORDING TO THE SURVEY OF DOCTORS by Светлана Ивановна Токмакова, Людмила Юрьевна Побединская, Ольга Владимировна Бондаренко, Юлия Васильевна Луницына, Мария Ивановна Фролова, Людмила Николаевна Тупикова, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Кира Борисовна Мозес, Яэль Центер

“…Purpose – to analyze problem areas in the provision of state and commercial dental care in the Altai Territory. Material and methods. A survey of 212 dentists of the Altai Territory was conducted. …”
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Burns and COVID-19, what is the impact of the pandemic? Epidemiological profile of a burn center between 2018-2022 by Tiago Ferrari, Marília Vilela Galhardo, Camila Cressoni de Oliveira, Wilson Falco Neto, João Felipe Pissolito, Rodolpho Cesar Oliveira Mellem Kairala, Pedro Henrique Soubhia Sanches, José Antônio Sanches

“…The overall objective of the project was to describe the epidemiological profile of patients in a Burn Treatment Unit. Methods: The study was a chart review from January 2018 to May 2022, including a sample of 1164 admissions from Hospital Padre Albino (Catanduva, São Paulo, Brazil). …”
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Effectiveness of Educational Intervention on Improving Preventive Behaviors in Fireworks Injuries: Applying the Extended Parallel Process Model by Majid Barati, Khadijeh Ezzati Rastgar, Sharareh Bagheri, Jahanbakhsh Usefi, Ameneh Hosseini, Samrand Saeedi, Golaleh Parandan

“…The present study aimed to investigate the effectiveness of the developed parallel process model in injury prevention in students. Materials & Methods: This experimental study was conducted in 2020-21 with 240 male students in Sanandaj who were randomly and equally divided into experimental and control groups. …”
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Efficacy of adding dexmedetomidine as adjuvant with bupivacaine in ultrasound-guided intermediate cervical plexus block for thyroidectomy surgery: randomized controlled study by Mamdouh Mahmoud Mostafa, Reham M. Gamal, Aya M. Ahmed Baiomy, Mohamed Elsayed Hassan, Jehan Mohamed Kamal, Thabet TS, Tamer A. Kotb, Mai M. Elrawas

“…The secondary outcomes were the total amount of fentanyl consumed intraoperatively, total patient’s opioids requirements within 24 h postoperative, VAS, and complications. Methods This randomized controlled double-blinded study included 60 patients aged 18 to 60 years, all of whom underwent thyroidectomy for thyroid cancer. …”
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Diversity and variability of biomolecules under material and environmental factors in Cymbopogon citratus L., traditional uses, antimicrobial properties, and recommendations for fu... by Noura Jaouad, Ahmed Tazi, Faouzi Errachidi, Souad Maache, Belkheir Hammouti, Mustapha Taleb

“…These chemicals were variable between extracts and essential oils depending on plant materials, growing conditions, and extraction methods. Due to their richness in chemicals, different parts and extracts of Cymbopogon citratus are used in traditional medicine to manage anticancer, antimicrobial, antidiarrheal, antiamoebic, antifilarial, antiseptic, antitussive, analgesic, anesthetic, and anti-inflammatory diseases. …”
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Speciation studies of potentially toxic elements within the vicinity of major dumpsites in Ile-Ife, Osun State, Nigeria by Oluwakemi O. Tovide, John A.O. Oyekunle, Odunayo T. Ore, Bukola A. Oyebode, Elizabeth O. Moseri, Abolanle S. Adekunle, Oluwasegun Oluwarotimi, Aderemi O. Ogunfowokan, Adebayo O. Eludoyin

“…Background: This study evaluated the concentrations, speciation, and environmental risks of aluminium (Al), cadmium (Cd), manganese (Mn), lead (Pb), zinc (Zn), and copper (Cu) in the major refuse dumpsite soils of Ile-Ife, Osun State, Nigeria. Methods: Soil samples were collected from refuse dumpsite soils in Ile-Ife, Osun State, Nigeria. …”
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Effects of Six-week Hopping Exercise on Time to Stabilization and Perceived Stability in Athletes With Chronic Ankle Instability During Single-leg Jump-landing by Mohammad Karimizadeh Ardakani, Hooman Minoonejad, Erik Wikstrom, Reza Rajabi, Ali Sharifnezhad

“…This is a randomized controlled trial.Materials and Methods: A total of 28 basketball players with chronic ankle instability (Mean±SD age; 22.67±2.88 y, Mean±SD weight: 80.47±8.48 kg, Mean±SD height: 186.82±3.09 cm) participated in this study and were randomly divided into two equal groups of 14 people each: 1. …”
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A randomized double-blind active-controlled clinical trial on the efficacy of topical basil (Ocimum basilicum) oil in knee osteoarthritis by Alireza Askari, Fatemeh Sadat Hasheminasab, Fatemeh Sadat Hasheminasab, Omid Sadeghpour, Mohammad Mehdi Naghizadehd, Seyed Ali Ravansalar, Aida Iraji, Mohammad Hashem Hashempur

“…BackgroundBasil is a widely used herb in Persian medicine and is gaining recognition as a functional food worldwide.Aim of the studyThis trial aimed to assess the effectiveness of a traditional formulation of basil oil in comparison with diclofenac gel in treating knee osteoarthritis, considering its established anti-inflammatory, anti-nociceptive, and anti-oxidative properties.Materials and methodsOne hundred eligible patients were equally randomized to the traditional basil oil (containing sesame oil) and diclofenac gel groups. …”
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Insightful health assessment of paediatric hemato-oncology patients’ well-being through knowledge and attitude survey of their caretakers: A hospital-based study by Miria Aingel Cherian, Nirali Dilip Patil, Manjula Gudhoor, Rhea Simon, Soukhya Kapsi, Abhilasha Sampagar, Madiwalayya S. Ganachari

“…The purpose of the current study was to measure the overall general well.being of paediatric hemato. oncology patients. Methods: The project was conducted in paediatric hemato.oncology department. …”
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Effective inhaler technique education is achievable - assessment and comparison of five inhaler devices errors by Monika Marko, Magdalena Klimczak, Marharyta Sobczak, Maciej Wojakiewicz, Tomasz Dębowski, Andrzej Emeryk, Andrzej Emeryk, Rafał Pawliczak

“…ObjectiveThe study is based on a respiratory educational program aimed at training medical personnel to use inhalers correctly and educating patients on improving their inhalation skills.MethodsAdult patients with asthma were divided into groups according to the inhaler: Ellipta, Diskus, Cyclohaler, Pressurized metered-dose inhaler (pMDI), and Turbuhaler. …”
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Comparative evaluation of simulators for practising fluoroscopy-guided renal pelvic puncture by N. K. Gadzhiev, D. S. Gorelov, A. A. Mishchenko, V. P. Britov, R. R. Kharchilava, E. F. Sharafutdinov, S.  B. Petrov, D. D. Shkarupa

“…To evaluate a non-biological model of the pelvicalyceal system puncture simulator UroATOM (“Alfa-Rhythm”, Russian Federation) and to compare it with a virtual reality simulator PERC MentorTM (“Simbionix”, Beit Golan, Israel).Materials & methods. The results of fluoroscopic guided puncture training were analyzed among 50 physicians. …”
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Hb H disease associated with compound heterozygosity for --SEA deletion and a novel alpha globin chain variant (HBA2:c.175C>A) on the distal histidine in a Chinese family by Manna Sun, Jiwu Lou, Wang Xinghe, Ying Zhao, Yunshi Dai, Shuangai Liu, Tizhen Yan

“…However, a subset of cases is attributed to rare haemoglobin variants, which can manifest with borderline or normal screening results, potentially leading to missed diagnoses in clinical practice.Methods: Blood samples were collected from family members and underwent haematological, DNA and RNA analysis.Results: The five-month-old proband presented a haematological phenotype consistent with Hb H disease. …”
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Morphological characteristics of lateral branches of human basilar artery by Gajanin Vesna, Sladojević Igor, Šarović-Vukajlović Mirka, Gajanin Radoslav, Ninković-Baroš Đuka, Krivokuća Božo

“…The aim of this study was to determine the morphological characteristics of lateral branches and side branches of the individual lateral branches of human basilar artery. Methods. The research was done on 25 anatomical specimens of adult brainstems, both sexes, previously fixed by immersion in a 10% formalin. …”
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Impact of nutrient deficiencies on early childhood caries: A case-control study on Vitamin D, Calcium, and Ferritin serum levels by Mohamed T Elfezary, Shaimaa Eldeeb, Mohamed E Moteea, Mohammad S Abu Samadah, Ahmed S Waly

“…Therefore, research was designed to examine the relationships between blood levels of vitamin D, calcium, ferritin and the occurrence of Early Childhood Caries. Materials and Methods: This case‒control study included a cohort of fifty Egyptian children aged 2 to 6 years who were segregated into two equal groups: the case group (Early Childhood Caries) and the control group (free from caries). …”
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Is “Bite force” a reliable parameter to compare masticatory efficiency restoration following ORIF of anterior mandibular fractures? by Shital Patel, Kruna Bhimani, Roma Narsingyani, Zenish Bhatti, Rajan Savani

“…The main objective of this study was to compare the efficacy of 3-dimensional (3D) miniplate and conventional miniplates for fixation of anterior mandibular fractures on the basis of bite force as a main parameter. Methods: 66 patients having isolated anterior mandibular fractures were randomized into two groups equally: Conventional miniplates and 3D miniplates. …”
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Open Drug Scenes Survey in Brazilian cities: main findings from São Paulo, Fortaleza, and Brasília by Clarice Sandi Madruga, Kátia Isicawa de Sousa Barreto, Danilo Seabra, André Constantino Miguel, Cláudio Jerônimo da Silva, Gleuda Simone Apolinário, Guilherme Godoy, Lidiane Nogueira Rebouças, Natália Alexandre Ferreira, Quirino Cordeiro, Rogério Adriano Bosso, Ronaldo Ramos Laranjeira

“…ABSTRACT Objective: The latest edition of the Open Drug Scenes Survey in Brazilian Cities (LECUCA) investigated social vulnerability, health, and the use of the Psychosocial Care Network by attendees of open drug scenes (ODSs) involving crack cocaine in São Paulo, Fortaleza, and Brasília between 2021/2022. Methods: Since 2016, LECUCA has used Time-Location Sampling (TLS) to select probabilistic samples representative of the population of ODS attendees. …”
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High-risk medication errors: Insight from the UK National Reporting and learning system by Abdulrhman Alrowily, Khalid Alfaraidy, Saleh Almutairi, Abdullah Alamri, Wejdan Alrowily, Mohammed Abutaleb, Mohammad Zaitoun, Waddad Sarawi, Mashael Aljead

“…Objectives: To conduct a retrospective analysis of incidents related to patient safety in the UK based on data from the National Rporting and Learning System (NRLS). Methods: This study was conducted based on a review of the National Reporting and Learning System (NRLS) patient safety reports published between January 1, 2015, and December 31, 2015. …”
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Factors that can influence postpartum depression: study in a reference hospital in the amazon region by Thaisy Luane Gomes Pereira Braga, Letícia Fonseca Macedo, Maria Eduarda Bührnheim Silveira, Társis da Silva Sousa, Mariseth Carvalho de Andrade, Rita de Cássia Silva de Oliveira, Lêda da Silva Lima

“… Objective: Investigate from the clinical epidemiological profile, factors that may influence the possibility of Postpartum Depression (PPD) in pregnant women assisted at the Santa Casa de Misericordia do Pará Foundation. Methods: This was a prospective, descriptive, cross-sectional cohort study with a quantitative approach. …”
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