The impact of age on genetic risk for common diseases. by Xilin Jiang, Chris Holmes, Gil McVean

“…Here, we introduce methods to infer the form of the longitudinal relationship between genetic relative risk for disease and age and to test whether all genetic risk factors behave similarly. …”
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Effects of combined training performed two or four times per week on 24-h blood pressure, glycosylated hemoglobin and other health-related outcomes in aging individuals with hypert... by Rodrigo Ferrari, Lucas Betti Domingues, Leandro de Oliveira Carpes, Paula de Azevedo Frank, Vinícius Mallmann Schneider, Sandra C Fuchs, GET Study Group

“…<h4>Purpose</h4>To compare the effects of a combined training program (resistance plus aerobic exercise) performed four or two times per week on 24-h ambulatory blood pressure and other health-related outcomes in middle-aged and older individuals with hypertension.<h4>Methods</h4>This study will be a randomized, parallel group, two-arm, superiority trial. …”
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Quality of recovery (QoR-15) following opioid-free versus opioid anaesthesia for elective endoscopic nasal surgeries: A randomised, open-label comparative trial by Yashika Pandey, Manisha Sapate, Harsha H. Narkhede, Poonam Mane

“…Methods: A randomised, open-label trial was conducted to evaluate the quality of recovery (QoR). …”
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The Relationship of Neck pain and Smart Phones Usage among students: A Cross-Sectional Study in Erbil City by ShwanQadir Media, Alaa Usama Ahmed

“…The aim of this study was to find the prevalence of neck pain induced by smart phones usage among students of medical faculty in Erbil city. Methods: A cross-sectional study on 400 students from Hawler Medical University was conducted from 1st July 2021 till 1st July 2022.The investigator designed a self-administered questionnaire, distributed it to the students. …”
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Metabolic syndrome treatment: focusing on acarbose by I. E. Chazova, B. B. Mychka

“…To compare the effectiveness of alpha-glucosidase inhibitor acarbose (150 or 300 mg/d) and non-pharmaceutical lifestyle modification in controlling arterial hypertension (AH), carbohydrate and lipid metabolism, and body weight (BW) among patients with impaired glucose tolerance (IGT) and AH.Material and methods. The study included 380 patients with Stage I-II AH, abdominal obesity (АО), and IGT. …”
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Prevalence of Cardiovascular Risk Factors in the Population of the Area I in the Municipality of Cienfuegos by Hilda María Delgado Acosta, Karelis Lastre Navarro, María Lina Valdés Gómez, Mikhail Benet Rodríguez, Alain Morejón Giraldoni

“…<strong><br />Objective:</strong> to identify the prevalence of cardiovascular risk factors in the population of the Area I in the municipality of Cienfuegos during 2010-2011. <strong><br />Methods:</strong> a descriptive cross-sectional study was conducted to determine the prevalence of cardiovascular risk factors in the population of the Area I in Cienfuegos by means of a complex three-stage equal probability sample of 581 people. …”
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Push-Out Bond Strength of Experimental Apatite Calcium Phosphate Based Coated Gutta-Percha by Afaf Y. Al-Haddad, Muralithran G. Kutty, Zeti Adura Che Ab Aziz

“…To evaluate the push-out bond strength of experimental apatite calcium phosphate coated gutta-percha (HAGP) compared to different commercially available coated gutta-percha root obturation points. Methods. Extracted teeth were selected and instrumented using ProTaper rotary files. …”
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Sample sizes for non-inferiority studies based on the difference between two proportions: a unified approach for difference, ratio and odds ratio models by Bruno Mario Cesana, Paolo Antonelli

“…Background: It is never easy to make sample size calculation for two-arm, non-inferiority studies with a primary proportion outcome not only because the different parameterisations involved in the difference, ratio, and odds ratio models lead to different non-inferiority margins and different sample size results, but also because of the different efficiency of the respective sample size formulae. Methods: According to a formal statistical approach, we showed how to express the non-inferiority margins of the three models by keeping the probability (success or failure) of the standard treatment fixed (considered as “known” in the planning phase of a trail), and equal under the null and alternative hypotheses as the statistical basis for sample size calculation. …”
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Disputing Authorship: Reinscriptions of Collective Modes of Knowledge Production by Andréa Gill, Marta Fernández

“…This entry point into the conversation on who has the power to know and control the meanings of intersectional inequalities enables a focus on practice, pedagogy, and methods to unpack the ethical and epistemological questions at hand. …”
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Cost-effectiveness of pirfenidone compared to all available strategies for the treatment of idiopathic pulmonary fibrosis in France by Emilie Clay, Olivier Cristeau, Romain Chafaie, Alexandrina Pinta, Benjamin Mazaleyrat, Vincent Cottin

“…Objective: To update the health economic evaluation of pirfenidone in the treatment of idiopathic pulmonary fibrosis (IPF) compared to all available alternatives strategies (Best supportive care – BSC and nintedanib), based on a cost-utility model previously validated by the CEESP’s (French Committee for Economic Evaluation) in 2014. Methods: A standard Markov cohort model, adapted to French methodology guidelines, was used to simulate the therapeutic management and the course of IPF patients (including potential adverse events) using the collective perspective. …”
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Pengaruh Media Pop Up Book Terhadap Hasil Belajar Ilmu Pengetahuan Alam dan Sosial (IPAS) Siswa Kelas V SD Negeri 88 Singkawang by Hengki, Mertika, Dewi Mariana

“…A type of quantitative research with experimental methods. Research Design Nonequivalent Control Group Design. …”
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Elucidating the Differential Mechanisms of Jingui Shenqi Pill and Mingmu Dihuang Pill in the Treatment of Diabetic Nephropathy Based on Yin-Yang Theory by Bi S, Xu Z, Yuan A, Wang Z, Liu Y, Yu B, Tian J, Liu C, Qiao L, Wang Z, Zhang Y

“…., Ltd, Beijing, 100000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yanling Zhang, Email zhangyanling@bucm.edu.cn Zhibin Wang, Email wangzhibin4804@126.comBackground: The Yin-Yang attributes of MMDH and JGSQ in treating diabetic nephropathy (DN) remain unexplored.Methods: UPLC-MS identified formula components, network pharmacology analyzed common DN targets, and in vitro renal fibrosis models assessed efficacy. …”
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Decentralizing Democracy: Secure and Transparent E-Voting Systems with Blockchain Technology in the Context of Palestine by Eman Daraghmi, Ahmed Hamoudi, Mamoun Abu Helou

“…Elections and voting play a crucial role in the development of a democratic society, enabling the public to express their views and participate in the decision-making process. Voting methods have evolved from paper ballot systems to e-voting systems to preserve the integrity of votes, ensuring a secure, transparent, and verifiable process. …”
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Public Goals and Government Expenditures: Are the Solutions of the “Modern Monetary Theory” Realistic? by I. M. Stepnov, Ju. A. Kovalchuk, M. V. Мelnik, T. Petrovic

“…Therefore, the purpose of the study is to generalize the results of the discussion about the possibility of changing the economic “mainstream” to the “modern monetary theory” (MMT) and its prospects in public finance management. The research methods include systematic, critical, comparative and cross-country analysis and verification of the realism of the MMT’s proposals. …”
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Comparative Study of Implant Placement Techniques and Their Effect on Long-Term Success of Implant-Supported Restorations by Priya Nagar, Zakir Husain, Utkarsh Gupta, Malav Sheth, Rahul Mishra, HL Muthuraj

“…Background: The long-term success of implant-supported restorations is influenced by various implant placement techniques. Materials and Methods: This randomized controlled trial involved 120 patients requiring dental implants, divided into three equal groups based on the implant placement technique: Group A (conventional submerged), Group B (one-stage non-submerged), and Group C (guided surgery). …”
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Comparison of the effects of eight weeks of resistance training and ginseng supplementation on growth hormone and insulin resistance in Syrian male mice under lower extremity suspe... by Zahra Goli, khosro Jalali Dehkordi, Gholamreza Sharifi

“…Therefore, The purpose of the present study was to compare the effects of eight weeks of resistance exercise, consumption of ginseng supplementation on growth hormone and insulin resistance in Syrian mice with lower limb suspension. Materials and methods: In this study, 50 male mice were devided into five equal groups including suspension control, suspension+resistance exercise, suspension+ginseng extract, suspension+resistance exercise+ginseng extract, and control (normal conditions). …”
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Anxious Depression in Major Depressive Disorder: Key Influences and Prevalence in Chinese Hospitalized Patients by Zhu Y, Yin W, Ma J, Zhang L

“…Our study aimed to determine the frequency of AUD in Chinese patients with MDD during their first hospitalization and to identify factors that may influence the emergence and intensity of these AUD.Methods: This study enrolled 981 Chinese MDD patients on their inaugural hospital admission. …”
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The effect of a moderate-intensity interval training on the plasma levels of LDL receptor-related protein-1 (LRP1) and cerebral and plasma levels of amyloid beta in induced Alzheim... by Mostafa Zarin Afzal, Yaser Kazemzadeh, Saeed Sedaghati, Sanaz Mirzayan, Abdolali Banaeifar

“…The aim of the present study was to investigate the effect of moderate-intensity interval training the plasma levels of LDL receptor-related protein-1 (LRP1) and cerebral and plasma levels of amyloid beta in induced Alzheimer's rats. Materials and methods: For this purpose, 30 eight-week-old Wistar rats with an average weight of 191±10 g were randomly divided into three equal groups: Aβ+exercise, Aβ, and the control group. …”
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Integrated action mechanism of women's participation in rural residential environment governance: Embedded dual case analysis based on Sanmen County, Zhejiang Province by QIN Xiaomin, SU Hao

“…[Objective] This study aims to explore how to fully activate women's agency and gender-specific strengths in rural residential environment governance, offering new strategies to enhance the effectiveness of environmental governance. [Methods] Drawing on ecofeminism, human-environment interaction theory, and actor network theory, this study constructs an analytical framework to deeply examine the forms and mechanisms of women's participation in rural residential environment governance, based on an embedded dual case study in Sanmen County. …”
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The One Anastomosis Gastric Bypass Is a Suitable Alternative to Roux-en-Y Gastric Bypass in Patients with Body Mass Index ≥50 kg/m2: A Propensity Score-Matched Analysis by Lindsy van der Laan, Dionne Sizoo, Loek J.M. de Heide, André P. van Beek, Marloes Emous

“…Both procedures resulted in equal weight loss, remission of comorbidities, and short-term complications. …”
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