Worldwide Research Trends on Lung Cancer and Microbiota: A Bibliometric and Visualized Analysis by Ren YF, Tan SY, Wang Q, He JW, You FM, Ma Q, You LT

“…This study employs bibliometric methods to trace trends and advancements, emphasizing the extraction and analysis of clinical research data, and outlines current challenges and future research directions.Methods: We selected the literature in the Web of Science Core Collection database. …”
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Mechanisms of Acetate in Alleviating SETDB1-Linked Neuroinflammation and Cognitive Impairment in a Mouse Model of OSA by Zhao Z, Xiang L, Hong JS, Wang Y, Feng J

“…We aimed to investigate roles of acetate (ACE) and SET domain bifurcated histone lysine methyltransferase 1 (SETDB1) in neuroinflammation of OSA.Methods: After C57BL/6J mice were exposed to OSA-associated intermittent hypoxia (IH) or normoxia for four weeks, the composition of the gut microbiota (GM) and the levels of serum short-chain fatty acids (SCFAs) were measured by 16S rRNA and GC-MS methods, respectively. …”
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Updated Surveillance Metrics and History of the COVID-19 Pandemic (2020-2023) in Canada: Longitudinal Trend Analysis by Scott A Wu, Alan G Soetikno, Egon A Ozer, Sarah B Welch, Yingxuan Liu, Robert J Havey, Robert L Murphy, Claudia Hawkins, Maryann Mason, Lori A Post, Chad J Achenbach, Alexander L Lundberg

“…MethodsThis longitudinal study analyzed trends in traditional surveillance data and dynamic panel estimates for COVID-19 transmissions and deaths in Canada from June 2020 to May 2023. …”
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Integrating Bulk and Single-Cell Transcriptomic Data to Identify Ferroptosis-Associated Inflammatory Gene in Alzheimer’s Disease by Zhou H, Peng Y, Huo X, Li B, Liu H, Wang J, Zhang G

“…Finally, candidate genes were validated in ferroptosis models using reverse transcription quantitative PCR (RT-qPCR) and immunofluorescence methods.Results: Bulk RNA-seq analysis identified SLC11A1, an inflammatory gene associated with AD. …”
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Health Economics Evaluation of Bictegravir/Emtricitabine/Tenofovir for a First-Line Treatment of HIV-1 Infection in China by Wang W, Zhou D, Zhou K, Zhang D, Li H, Zhang H, Jiang X, Wang R, Wang X, Tang W

“…Wenjuan Wang,1,* Dachuang Zhou,1,* Kejia Zhou,1 Di Zhang,1 Hao Li,1 Hongliu Zhang,1 Xin Jiang,1 Ruihua Wang,1 Xi Wang,2 Wenxi Tang1 1Center for Pharmacoeconomics and Outcomes Research, China Pharmaceutical University, Nanjing, Jiangsu Province, 211198, People’s Republic of China; 2Infection Center, Beijing You’an Hospital, Capital Medical University, Beijing, 100069, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenxi Tang, Email tokammy@cpu.edu.cn Xi Wang, Email wangxi35@ccmu.edu.cnPurpose: This study aims to evaluate the economic value of Bictegravir/emtricitabine/tenofovir (B/F/TAF) as a first-line treatment for HIV-1 infection in China, where such evaluations are currently lacking.Patients and Methods: We developed a monthly-cycle Markov model to evaluate the economics of B/F/TAF versus dolutegravir/lamivudine (DTG/3TC) as a first-line ART for adult HIV-1 patients over a lifelong time. …”
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Causal Effects of Inflammatory Cytokines and Immune Cell Phenotypes on Spontaneous Abortion: Evidence From Mendelian Randomization by Lin S, Tian X, Kong S, Zhang B, Wang S, Zhu K, Liu X, Yeung WSB, Cao D, Yao Y

“…Shaochong Lin,1– 3,* Xiangming Tian,4,* Sijia Kong,5 Bolun Zhang,1– 3 Sidong Wang,2,6 Kongfu Zhu,2 Xiaomin Liu,7,8 William S B Yeung,2,6 Dandan Cao,2 Yuanqing Yao1– 3 1School of Medicine, Nankai University, Tianjin, People’s Republic of China; 2Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, Shenzhen, People’s Republic of China; 3Department of Obstetrics and Gynecology, The First Medical Center of Chinese PLA General Hospital, Beijing, People’s Republic of China; 4Medical Center for Human Reproduction, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 5Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, Shenzhen, People’s Republic of China; 6Department of Obstetrics and Gynecology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People’s Republic of China; 7Shenzhen Key Laboratory of Human Commensal Microorganisms and Health Research, Shenzhen, People’s Republic of China; 8College of Life Sciences, University of Chinese Academy of Sciences, Beijing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuanqing Yao, Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, No. 1 haiyuan 1st Road, Futian District, Shenzhen, People’s Republic of China, Email yaoyq_hkuszh@126.com Dandan Cao, Shenzhen Key Laboratory of Fertility Regulation, Reproductive Medicine Center, The University of Hong Kong-Shenzhen Hospital, No. 1 haiyuan 1st Road, Futian District, Shenzhen, People’s Republic of China, Email caodd@hku-szh.orgPurpose: This study aims to investigate the causal relationship between inflammatory cytokines, immune cells and spontaneous abortion (SA).Methods: A bidirectional two-sample Mendelian randomization (MR) analyses was conducted based on the genetic data of 91 inflammatory cytokines (n=14,824), 731 immune traits (n=3757) and SA (18,680 cases and 162,987 controls) cohorts. …”
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The Value of Using Bedside Point of Care Testing for International Normalized Ratio in Patients on Warfarin Undergoing Dental Procedures and Bleeding Assessment; A Single Center Pr... by Albarkheel A, Alshareef H, Albar A, Altbaili SY, Alminaqash MA, Alotibie A, Sheikh A, Alahmadi A, Alaifan B, Tamim H, Owaidah T

“…INR measurements were performed using both point-of-care devices and laboratory methods. One-way ANOVA compared INR values across bleeding severity groups and procedure types. …”
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Clinical features of the pulmonary tuberculosis course combined with different diabetes mellitus types in the Zaporizhzhia region by O. M. Raznatovska, Yu. M. Bobrovnycha-Dvizova

“…The outcomes of the study were processed by modern analysis methods on a personal computer using the statistical package of the Statistica® for Windows 6.0 (StatSoft Inc., No. …”
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AQP1 Affects Necroptosis by Targeting RIPK1 in Endothelial Cells of Atherosclerosis by Wang P, Zheng L, Yang Y, Yue X, Liu J, Fan K, Zhou H, Dong H

“…Then we collected femoral atherosclerosis and normal aortic samples, further conducted single-cell sequencing and spatial transcriptomic methods to confirm the potential function and pathway of AQP1 in endothelial cells. …”
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DENTAL STATUS IN CHILDREN WITH MALIGNANT SOLID NEOPLASMS by Yu.V. Popelo

“…The urgency of this issue is due to a pronounced tendency to a rapid increase in the prevalence of disease with malignant formation, which requires a detailed study of the efficiency of already implemented methods and improving or developing new schemes for the sustainable maintenance of dental health in patients of this profile. …”
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Genome Variability for the Development of Coronary Heart Disease in Type 2 Diabetes Mellitus: A Bibliometric Analysis by Bekenova NB, Vochshenkova TA, Zhylkybekova A, Ablakimova N, Mussin NM, Albayev RK, Kaliyev AA, Tamadon A

“…The aims of this study are to employ bibliometric analysis methods for mapping the array of research on genome variability concerning the development of coronary heart disease in individuals with type 2 diabetes mellitus.Methods: We derived the data from the Web of Science (WoS) Core Collection database and Scopus on January 6, 2023. …”
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Genomic Characterization and Antimicrobial Resistance of ESBL-Producing, Escherichia coli Isolates in Suzhou, China by Wang C, Zhang H, Zhao R, Tsui CKM, Deng S

“…Cailin Wang,1,* Hong Zhang,2,* Rongfen Zhao,2 Clement Kin-Ming Tsui,3– 5 Shuwen Deng1 1Medical Research Center, People’s Hospital of Suzhou New District, Suzhou, Jiangsu, People’s Republic of China; 2Department of Medical Microbiology, People’s Hospital of Suzhou New District, Suzhou, Jiangsu, People’s Republic of China; 3Infectious Disease Research Laboratory, National Centre for Infectious Diseases, Tan Tock Seng Hospital, Singapore, Singapore; 4Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore; 5Faculty of Medicine, University of British Columbia, Vancouver, BC, V6T1Z3, Canada*These authors contributed equally to this workCorrespondence: Shuwen Deng, Email danyanghhh@qq.com Clement Kin-Ming Tsui, Email clementsui@gmail.comBackground: The prevalence of third-generation cephalosporin-resistant and extended-spectrum beta-lactamases (ESBL) producing Escherichia coli poses a significant global public health concern due to their resistance to multiple antibiotics; however, their prevalence and epidemiological patterns in China are not very well investigated.Objective: This study aimed to investigate the molecular epidemiology, and antimicrobial susceptibility of ESBL-producing E. coli among clinical isolates in China.Methods: Phenotypic ESBL-producing E. coli isolates were collected from in-patients at a non-tertiary hospital in Suzhou from 2018.06.01 − 2019.11.30. …”
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Macrophage Membrane Coated Manganese Dioxide Nanoparticles Loaded with Rapamycin Alleviate Intestinal Ischemia-Reperfusion Injury by Reducing Oxidative Stress and Enhancing Autopha... by Sheng R, Wang W, Zeng W, Li B, Yu H, Li X, Liang Y, Wang Y, Liao Y, Liu D

“…The aim of this study is to fabricate macrophage membrane-coated manganese dioxide nanospheres loaded with rapamycin [Ma@(MnO₂+RAPA)] for alleviating intestinal I/R injury.Methods: We engineered honeycomb MnO2 nanospheres coated with a macrophage membrane to act as a drug delivery system, encapsulating RAPA. …”
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Spatial Analysis of Bioclimatic Vulnerability of Kermanshah Facing Heat Wave by Hossein Yavari, Mstafa Karampour, Dariush Yarahmadi

“…To distinguish days with extreme air temperature, we used the method of (Fumiaki et al., 2007) that is called normalized temperature deviation or Fumiaki index. …”
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Parent-child relationship and family system characteristics in families of adolescents with multiple sclerosis by E. A. Boyko, E. V. Ivanchuk, K. R. Latii, V. L. Malygin, O. V. Bykova, T. T. Batysheva

“…Due to the severity and clinical presentations of the disease in children, sociopsychological aspects, including parent-child relationships (PCR), is the focus of attention.Objective: to study of the characteristics of PCR in families of children with MS.Patients and methods: Ten families of MS adolescents (a study group), and 10 families of healthy adolescents (a control group) were examined. …”
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Perspectives of nurses and patients on the misplacement of supportive care information for type 2 diabetes mellitus: a qualitative study in China by Ying Li, Chao Li, Na Zhou, Runli Fan, Ling Nie, Fangfang Wu, Huili Zhou, Liqun Yao, Huiyue Zhou

“…Abstract Objective This study aimed to investigate the perspectives of nurses and patients on the misplacement of supportive care information for type 2 diabetes mellitus (T2DM). Methods A descriptive qualitative study was conducted using purposive sampling to recruit elderly individuals diagnosed with T2DM and nurses from a geriatric hospital in the central region of China. …”
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Development and temporal evaluation of sex-specific models to predict 4-year atherosclerotic cardiovascular disease risk based on age and neighbourhood characteristics in South Lim... by Anke Bruninx, Lianne Ippel, Rob Willems, Andre Dekker, Iñigo Bermejo

“…For males, the AUROC of the final model equalled 0.6548. The E/O equalled 0.9466. For females, the AUROC equalled 0.6744. …”
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THE COSTS OF REGIONAL ANESTHESIA WITH THE USE OF LEVOBUPIVACAINE, RACEMIC BUPIVACAINE AND ROPIVACAINE by G. E. Ulrikh, A. V. Rudakova

“…The aim of this work was to assess the cost of anesthesia levobupivacaine, bupivacaine and ropivacaine.Material and methods. In accordance with the results of comparative clinical trials and expert evaluation analysis was conducted in two ways: under the assumption of equal clinical effectiveness of levobupivacaine and bupivacaine and a higher efficiency of levobupivacaine compared with ropivacaine (assumed in various clinical situations with an equal volume of solution used ropivacaine in concentrations of 0.5% may be replaced without reducing clinical efficacy of levobupivacaine in a concentration of 0.5%, ropivacaine in a concentration of 0.75% – levobupivacaine in a concentration of 0.5 and 0.75% (in equal proportions); ropivacaine at a concentration of 1% – levobupivacaine at a concentration of 0.75%. …”
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Violation of the principle of progressivity and non-regressivity with the issuance of legislative act 01 of 2005 against the general pension system in Colombia by Gerson Yahir Vergel Ramirez, Jarvi Amaya Amaya, Leonardo Fabio Quintero Torres

“…Through this article it is intended to apply analytical methods purely to legal issues, that is, to divide them into as many parts as possible. …”
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Botanical extract combined with minoxidil improve hidrotic ectodermal dysplasia caused by p.G11R mutations: a case report by Shiyi Zhong, Chuhan Huang, Mingyue Zhuang, Qingwu Liu, Ziyuan Tian, Dingquan Yang

“…Purpose We aim to explore a potential treatment strategy for hair loss.Materials and methods A male 6-year-old child was diagnosed with hidrotic ectodermal dysplasia 2 (HED2) caused by GJB6 (p.G11R) mutations. …”
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