Comparing the impact of foot and hand reflexology on anxiety and physiological indices in colonoscopy candidates: A randomized clinical trial by Mohamad Golitaleb, Ali Safdari, Fatemeh Rafiei, Ameneh Yaghoobzadeh, Najmeh Mohamadi, Razieh Mokhtari

“…This study aimed to evaluate their effects on pre-colonoscopy anxiety and physiological parameters. Methods: This randomized clinical study was conducted from November 2022 to August 2023 at the Amir al-Momenin Educational and Therapeutic Center in Arak, Iran. …”
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Getting Up in the Morning and Chronotype in Relation to Polycystic Ovarian Syndrome: A Mendelian Randomization and Cross-Sectional Study by Dilimulati D, Lu J, Li J, Cai M, Zhang Y, Shao X, Chen H, Wan Q, He F, Yue C, Zhang M, Qu S

“…Diliqingna Dilimulati,1,* Jiayi Lu,2,* Jinghua Li,2,* Meili Cai,1 Yuqin Zhang,1 Xiaowen Shao,3 Haibing Chen,1 Qian Wan,4 Fang He,4 Chaoyan Yue,5 Manna Zhang,1,6 Shen Qu1 1Department of Endocrinology and Metabolism, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China; 2Department of Clinical Laboratory, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China; 3Department of Obstetrics and Gynecology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China; 4Department of Endocrinology and Metabolism, The First People’s Hospital of Chenzhou, Chenzhou, Hunan, 423000, People’s Republic of China; 5Department of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, 200011, People’s Republic of China; 6Department of General Practice, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, 200072, People’s Republic of China*These authors contributed equally to this workCorrespondence: Manna Zhang, Department of Endocrinology and Metabolism, Shanghai Tenth People’s Hospital, No. 301, Middle Yanchang Road, Jingan District, Shanghai, 200072, People’s Republic of China, Tel +86 13774448495, Email mannazhang@126.com Chaoyan Yue, Department of Laboratory Medicine, Obstetrics and Gynecology Hospital of Fudan University, No. 419, Fangxie Road, Huangpu District, Shanghai, 200011, People’s Republic of China, Tel +86 02133189900, Email 20111250007@fudan.edu.cnBackground: Although a connection between circadian rhythm and polycystic ovarian syndrome (PCOS) has been shown in previous studies, the exact cause of this association is not well understood.Purpose: This study aimed to use Mendelian randomization (MR) method to analyze the potential association between getting up in the morning and chronotype with PCOS, and a cross-sectional study was conducted to further validate these results.Methods: Using summary information from large-scale genome-wide association studies (GWASs) in people of European ancestry, we conducted univariable MR (UVMR) and multivariable MR (MVMR) analyses to examine the causal effect of genetically determined getting up in the morning and chronotype on PCOS. …”
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Association of <i>SEPT9</i> Gene Methylation with the Clinicopathologic Features and <i>Fusobacterium nucleatum</i> Infection in Colorectal Cancer Patients by Siew-Wai Pang, Subasri Armon, Jack-Bee Chook, Kaik-Boo Peh, Suat-Cheng Peh, Sin-Yeang Teow

“…For FN detection, a TaqMan probe-based method targeting the 16S rRNA gene was used. The differences in <i>mSEPT9</i> levels and FN expression between cancer and non-cancer tissues were evaluated. …”
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Investigating Falls Risk Awareness in Hospitals Using the Self‐Awareness of Falls Risk Measure (SAFRM): Empirical Research Quantitative by Elissa Dabkowski, Simon J. Cooper, Jhodie Duncan, Karen Missen

“…Setting Three rural/regional hospitals in the State of Victoria, Australia. Methods Using a purposive sampling strategy, patients were eligible to participate if aged ≥ 40 years, English‐speaking, and have ambulatory capacity prior to hospital admission. …”
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Gold Nanoparticles Functionalized With 5-Amino-2-Mercaptobenzimidazole: A Promising Antimicrobial Strategy Against Carbapenem-Resistant Gram-Negative Bacteria by Zhang J, Zhang X, Yao Z, Pan J, Ye J, Xia P, Zhou T, Cao J

“…This study introduces 5-amino-2-mercaptobenzimidazole (5-A-2MBI) functionalized gold nanoparticles (5-A-2MBI_Au NPs) and evaluates their antibacterial activity against CR-GNB.Methods: The 5-A-2MBI_Au NPs was synthesized using a one-pot method. …”
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A Clinical Risk Score Based on Albumin and Electrolyte Levels for Predicting Death Risk in Hospitalized Elderly COVID-19 Patients by Wang C, Zheng X, Bi S, Shao M, Xie Z, Wei N, Zhou Q, Feng S

“…Patients were classified into low- and high-risk groups using optimal segmentation thresholds, with survival curves generated by the Kaplan–Meier method. An online risk calculator was developed to facilitate real-time risk assessment in clinical settings.Results: The cohort included 1413 hospitalized COVID-19 patients. …”
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Acute tonsillitis and pediatric functional gastrointestinal disorders: the first result of a possible association analysis by E. R. Meskina, L. A. Galkina, T. V. Stashko

“…The aim is to discover a possible relationship between acute exudative tonsillitis and FDDS in children in the context of clinical and medico-social assessment. Materials and Methods: An observational cross-sectional study was performed using the continuous sampling method. …”
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Current Strategies to Reducing Interval Breast Cancers: A Systematic Review by Goh RSJ, Chong B, Yeo S, Neo SY, Ng QX, Goh SSN

“…We found that using digital breast tomosynthesis (a 3D imaging method) generally reduced missed cancers compared to traditional mammograms, especially in women with dense breasts. …”
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Exploring the Incidence and Risk Factors of Diabetic Nephropathy in Type 1 Diabetes: Insights from a Retrospective Cohort Study in Northwest China by Du Z, Liu X, Zhang L, Zhao H, Tian L

“…Zouxi Du,1,2,&amp;ast; Xiaoning Liu,3,&amp;ast; Leyuan Zhang,4 Hui Zhao,5,6 Limin Tian1,7 1The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, People’s Republic of China; 2Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, Gansu, People’s Republic of China; 3Department of Epidemiology and Health Statistics, School of Public Health, Lanzhou University, Lanzhou, Gansu, People’s Republic of China; 4The First Clinical College, Gansu University of Traditional Chinese Medicine, Lanzhou, Gansu, People’s Republic of China; 5College of Integrated Traditional Chinese and Western Medicine, Gansu University of Traditional Chinese Medicine, Lanzhou, Gansu, People’s Republic of China; 6Department of Nephrology, Gansu Provincial Hospital, Lanzhou, Gansu, People’s Republic of China; 7Department of Endocrinology, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Limin Tian, The First School of Clinical Medicine, Lanzhou University, Lanzhou, Gansu, 730000, People’s Republic of China, Email tlm7066@sina.comPurpose: The study aimed to investigate the incidence of diabetic nephropathy (DN) and their relationship with certain risk factors in patients with type 1 diabetes (T1D) across hospitals in Gansu Province, China.Methods: There were 434 T1D patients recruited from Gansu Province, China, in the present retrospective cohort study between January 2016 and December 2024. …”
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Nasal mRNA Nanovaccine with Key Activators of Dendritic and MAIT Cells for Effective Against Lung Tumor Metastasis in Mice Model by Li A, Cai X, Li D, Yu Y, Liu C, Shen J, You J, Qiao J, Wang F

“…Intranasal immunization has emerged as a more effective method of inducing local immune responses against cancer cells in the lungs.Methods: An innovative layered double hydroxide- and 5-OP-RU–based mRNA nanovaccine (Mg/Al LDH-5-OP-RU/mRNA) was synthesized via coprecipitation. …”
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Hypopharyngeal Squamous Cell Carcinoma in Elderly Patients Aged &amp;ge;70 Years: Surgery and Postoperative Radiotherapy Improves Outcomes in Selected Patients by Wang R, Hariri AA, Tao H, Wei Y, Lyu Z

“…Ru Wang,1,&amp;ast; Ahmad A Hariri,2,&amp;ast; Hengmin Tao,1 Yumei Wei,1 Zhenghua Lyu3 1Department of Head and Neck Radiotherapy, Shandong Provincial ENT Hospital, Shandong University, Jinan, Shandong, People’s Republic of China; 2Department of Otolaryngology-Head and Neck Surgery, London North West University Healthcare NHS Trust, London, England, UK; 3Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, Shandong, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Yumei Wei, Email 15553119268@163.com Zhenghua Lyu, Email entlvzhenghua@163.comObjective: To summarize the efficacy of surgery plus postoperative radiotherapy as initial treatment in elderly patients aged ≥ 70 years with advanced hypopharyngeal cancer and to analyze prognostic factors.Methods: Retrospective analysis of 77 elderly patients aged ≥ 70 years with stage III–IV hypopharyngeal squamous cell carcinoma who underwent surgery as initial treatment at Shandong Provincial ENT Hospital between 2006– 2020. …”
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Application of the Fuzzy Optimal Model in the Selection of the Startup Hub by Xinman Zhu, Jie Dai, Haoran Wei, Debing Yang, Weilun Huang, Zhang Yu

“…Lastly, the best idle land resulted in this case study with equal decision-making power using the fuzzy method is Taipei Jianguo Brewery, and the difference of decision-making power might make the best idle land to be Wanbao Textile Factory.…”
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Explore the Application Value of Metagenomic Next-Generation Sequencing of Bronchoalveolar Lavage Fluid in the Early Diagnosis of Pulmonary Tuberculosis by Lu Y, Zhang C, Wu J, Xu X, Lu A, Huang H, Chen M

“…Yangni Lu,1,&ast; Chunlan Zhang,1,&ast; Jianlin Wu,1 Xianli Xu,1 Ailian Lu,1 Huiya Huang,2 Maowei Chen1 1Department of Infectious Diseases, Wuming Hospital Affiliated to Guangxi Medical University, Nanning, Guangxi, People’s Republic of China; 2Department of General Medicine, Wuming Hospital Affiliated to Guangxi Medical University, Nanning, Guangxi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Maowei Chen, Email chenmaowei2008@163.com Jianlin Wu, Email wjl4954@163.comObjective: Compare the diagnostic efficacy of bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) with that of four traditional methods in the diagnosis of pulmonary tuberculosis (PTB), and explore the application value of BALF mNGS in the early diagnosis of PTB.Methods: A retrospective analysis was performed on 102 patients with suspected PTB in Wuming Hospital Affiliated with Guangxi Medical University from January 2021 to August 2024, among which 61 cases were PTB and 41 cases were non - PTB. …”
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UOT OF DENTISTS-ORTHOPEADISTS WORK OVER IMPLANTOLOGIC RECEPTION. REMOVABLE AND CONDITIONALLY REMOVABLE CONSTRUCTIONS by E.V. Diiev, T. V. Diieva, V. V Lepsky, V. V. Lepsky, V. A. Labunets

“…However, unlike traditional methods of patients’ prosthesis with complete edentia, methods of dental implantation in Ukraine do not have full legal status because of the lack of clinical technological protocols and complete lack of departmental time standards for doctors- orthopedists on their production. …”
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A Study on the Yield Stability of Oilseed Sunflower Genotypes under Drought Stress by Nasrin Akbari, Reza Darvishzadeh

“…Based on this, several methods have been introduced for selection with optimal efficiency and high accuracy. …”
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Is 2 h of Hypothermic Machine Perfusion for Pancreas Preservation Effective in Improving Graft Reperfusion? by Benoit Mesnard, MD, Christophe Masset, MD, PhD, Etohan Ogbemudia, MD, PhD, Sarah Bruneau, PhD, Mohamed Elzawahry, MD, Stéphanie Le Bas-Bernardet, PhD, David Minault, Jeremy Hervouet, Diego Cantarovich, MD, PhD, Jérôme Rigaud, MD, PhD, Lionel Badet, MD, PhD, Peter Friend, MD, PhD, Rutger Ploeg, MD, PhD, Gilles Blancho, MD, PhD, James Hunter, MD, PhD, Thomas Prudhomme, MD, Julien Branchereau, MD, PhD

“…Static cold storage (SCS) remains the standard method for organ preservation. The development of parenchymal edema during prolonged hypothermic machine perfusion (HMP) was a major barrier to the introduction of this technique for the preservation of pancreases. …”
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Comparative Effect of Massage Therapy versus Kangaroo Mother Care on Body Weight and Length of Hospital Stay in Low Birth Weight Preterm Infants by Priya Singh Rangey, Megha Sheth

“…Comparison of effectiveness of MT and KMC on body weight and length of hospital stay in low birth weight preterm (LBWPT) infants. Method. 30 LBWPT infants using convenience sampling from Neonatal Intensive Care Unit, V.S. hospital, were randomly divided into 2 equal groups. …”
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GENETIC ALGORITHM-PID CONTROLLER FOR MODEL ORDER REDUCTION PANTOGRAPHCATENARY SYSTEM by Nasir A. Al-Awad, Izz K. Abboud, Muaayed F. Al-Rawi

“…Then, the usage of Genetic Algorithm with Proportional-Integral-derivative (G.A-PID) as proposed controller appeared optimum response where, the contacts force consequences to be virtually equal to its steady reference. Finally it seems the advantageous of suggestion approach in contrast with classical manipulate strategies like, Internal mode control(IMC) method, linear quadratic regulator (LQR).The outcomes via the use of MATLAB simulation, suggests (G.A-PID) offers better transient specifications in contrast with classical manipulate. …”
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Regression Analysis to Predict the Length of Time to Complete a Thesis based on the Title by Al Aminuddin, Rahmat Hidayat, Gita Sastria, Astried Astried

“…This study utilizes the data mining method using machine learning, namely linear regression, in predicting how long it will take to complete a thesis title. …”
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Coexistence of a cross-diffusive West Nile virus model in a heterogenous environment by Abdelrazig K. Tarboush, Jing Ge, Zhigui Lin

“…The existence of coexistence states is presented by using a method of upper and lower solutions. The true positive solutions are obtained by monotone iterative schemes. …”
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