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3101
Efficacy and Safety of Transcatheter Arterial Chemoembolization Combined with Lenvatinib Plus Anti-PD-1 Inhibitors for Hepatocellular Carcinoma Patients with Extrahepatic Metastase...
Published 2024-11-01“…In this study, we aimed to determine the efficacy and safety of triple therapy in HCC patients with EM.Patients and Methods: This study retrospectively reviewed HCC patients with EM who received triple therapy and analyzed their survival rate using the Kaplan–Meier method. …”
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3102
Mendelian Randomization Analysis Identifies Causal Effects of Multi-Site Chronic Pain on Obstructive Sleep Apnea
Published 2025-03-01“…Zuxing Wang,1,* Lili Chen,1,* Ruishi Kang,2,* Zhuowei Li,2 Jiangang Fan,2 Yi Peng,3,* Yunqi He,4,5 Xiaolong Zhao2 1Sichuan Provincial Center for Mental Health, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Key Laboratory of Psychosomatic Medicine, Chinese Academy of Medical Sciences, Chengdu, 610072, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 3Department of Otorhinolaryngology Head and Neck Surgery, Second People’s Hospital of Chengdu, Chengdu, 610000, People’s Republic of China; 4Sichuan Provincial Key Laboratory for Human Disease Gene Study, Center for Medical Genetics and Department of Laboratory Medicine, Sichuan Provincial People’s Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, People’s Republic of China; 5Research Unit for Blindness Prevention, Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, Sichuan, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaolong Zhao, Email sczhaoxiaolong@163.com Yunqi He, Email yunqihe223@163.comBackground: Observational studies have suggested an association between obstructive sleep apnea (OSA) and chronic pain disorders, but causal evidence have not been confirmed.Methods: Here we performed Mendelian randomization (MR) study to explore the potential causal association and mediating roles of modifiable factors between multi-site chronic pain (MCP) and OSA. …”
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3103
Predictive Value of Advanced Lung Cancer Inflammation Index and Development of a Nomogram for Prognosis in Patients with Cervical Cancer Treated with Radiotherapy
Published 2025-04-01“…Overall survival (OS) and progression-free survival (PFS) were evaluated using the Kaplan–Meier method and Cox proportional hazards models. A nomogram was developed using prognostic factors based on multivariate analyses.Results: A total of 178 patients with cervical cancer were included. …”
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3104
The Role of Lifestyle Behaviors in Shaping the Relationship Between Chronic Pain and Epigenetic Age Acceleration: Evidence From NHANES 1998 to 2002
Published 2025-08-01“…This study aims to examine the relationship between chronic pain and epigenetic clocks in a nationally representative US sample and discover potential shared systemic mechanisms.Methods: This research comprised 2,532 individuals aged 50 and above from the 1999– 2002 National Health and Nutrition Examination Survey (NHANES) database. …”
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3105
Ridge splitting using autogenous bone wedge versus the conventional intercortical augmentation technique in horizontally deficient anterior maxilla: a randomized clinical trial
Published 2025-06-01“…Abstract Objectives This study aims to evaluate the quality and quantity of gained and maintained bone width after Ridge splitting utilizing autogenic bone wedge versus mixed bone particles for horizontal ridge augmentation in the anterior aesthetic zone. Materials and methods This randomized clinical trial included 20 patients with horizontally deficient anterior maxillary alveolar ridges. …”
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3106
Reliability of Cephalometric Lines as Indicators for Dentoalveolar Stability in Forensic Identification: A Cross-sectional Study
Published 2025-03-01“…Introduction: Cephalometric superimposition is an accepted method that has long been considered helpful for evaluating the growth and displacement of facial bones during orthodontic treatment. …”
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3107
Construction of a Prediction Model for Sleep Quality in Embryo Repeated Implantation Failure Patients Undergoing Assisted Reproductive Technology Based on Machine Learning: A Singl...
Published 2025-07-01“…Yanjun Zhao,1,* Chenying Xu,1,* Ningxin Qin,2,* Lina Bai,1 Xuelu Wang,1 Ke Wang2 1Operating Room, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Reproductive Medicine Center, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xuelu Wang, Email wangxuelu@51mch.com Ke Wang, Email wangkeyfy@126.comObjective: Constructing a predictive model for sleep quality in embryo Repeated Implantation Failure(RIF) patients using multiple machine learning algorithms, verifying its performance, and selecting the optimal model.Methods: Retrospective collection of clinical data from RIF patients who underwent assisted reproductive technology at the Reproductive Medicine Center of Tongji University Affiliated Obstetrics and Gynecology Hospital from January 2022 to June 2022, divided into a training set and a validation set in an 8:2 ratio. …”
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3108
EFFECT OF PERFLUORANE ON THE REGULATION OF SKIN BLOOD FLOW IN ACUTE BLOOD LOSS: EXPERIMENTAL STUDY
Published 2016-01-01“…The LDF (ЛАКК-02 device, LAZMA, Russia) method was used to record blood flow in the microvessels of the internal surface of the right ear. …”
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3109
Exploring the Analgesic Effect of Acupuncture on Knee Osteoarthritis Based on MLT/cAMP/PKA/CREB Signaling Pathway
Published 2025-01-01“…This study aims to explore this mechanism.Methods: In this work, the KOA rabbit model was constructed using the traditional Hulth method, and the therapeutic effect was assessed by the Lequesne MG score and Pain assessment by hot plate test. …”
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3110
Mendelian Randomization Combined with Single-Cell Transcriptome Analysis Reveals the Role of the Key Gene PCLAF in the Pathogenesis of Atopic Dermatitis
Published 2025-04-01“…The inverse variance weighted method facilitated MR analysis, while gene set enrichment analysis (GSEA) was used to identify pathways associated with AD. …”
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3111
A Novel pH-Responsive Nano-Sized Lanthanum-Doped Polyvinyl Alcohol-Carbon Quantum Dot Composite for Root Canal Irrigation
Published 2024-11-01“…In this study, we developed a novel material called La@PCDs by combining CQD-PVA and lanthanum for root canal irrigation.Methods: A one-pot hydrothermal method was used to prepare composites of lanthanum and CQD-PVA (La@PCDs). …”
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3112
Diagnostic Value of RDW-Albumin Ratio for the Prediction of Mortality in Sepsis Associated Nonthyroidal Illness Syndrome Patients: A Retrospective Cohort Study
Published 2024-12-01“…So we investigated it in this study.Methods: Patients with sepsis-associated NTIS admitted to Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, between March 2013 and April 2017 were included in the study. …”
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3113
Establishing the Median and 95% Effective Doses of Oliceridine for Immediate Post-Surgical Analgesia Following Laparoscopic Cholecystectomy: A Double-Blind, Sequential Dose-Finding...
Published 2025-04-01“…Using Dixon and Massey’s up-and-down sequential allocation method, the median effective dose (ED50) and the dose required for 95% effective dose (ED95) were determined, alongside an evaluation of the agent’s safety profile.Methods: In this prospective trial, 82 participants scheduled for LC were enrolled and randomly assigned to receive either oliceridine or saline (control). …”
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3114
Experiences, Challenges, and Needs of People Living with HIV in Hunan Province, China: A Qualitative Study
Published 2025-03-01“…Colaizzi’s seven-step analysis method and NVivo 14 was used to analyze the transcripts.Results: The participants, aged 23 to 83 years, had been living with HIV for durations ranging from one month to 19 years. …”
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3115
Correlation Between Intrinsic Capacity and Muscle Strength and Quality in Older Patients with Cardiovascular Disease: A Cross-Sectional Study
Published 2024-10-01“…This study aims to explore the relationship between the decline of IC, muscle strength, and muscle quality in older patients with CVD, providing a new method and basis for early recognition of IC decline in the older adults.Methods: This cross-sectional study included 475 older individuals from communities in Zhejiang. …”
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3116
Tritium in the urine of the Mayak PA workers in the period from 2017 to 2019
Published 2021-04-01“…Volume activity of tritium compounds was measured by liquid scintillation method using spectrometer Quantulus-1220. The samples were distilled or dried and then combusted using an automatic preparation and oxidization system Sample Oxidizer A307. …”
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3117
The socioeconomic burden of meningococcal infection in the Russian Federation
Published 2024-12-01“…To evaluate the socioeconomic burden of GFMI in the Russian Federation.Materials and methods. The study was conducted from the perspective of the healthcare system and society as a whole using a modeling method for children and adults, taking into account the following costs: 1) direct medical costs: emergency medical care, inpatient and outpatient treatment, and rehabilitation treatment; 2) direct non-medical costs: payment of dis ability pensions and temporary disability (TD); 3) indirect costs: loss of gross domestic product (GDP) and economic losses as a result of premature death from MI in childhood. …”
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3118
On-line Monitoring of H310BO3 Preparation from 10BF3
Published 2024-06-01“…The most reasonable feeding method for preparing H310BO3 from 10BF3 is that insoluble solid powder SrCO3 and H2O are mixed and stirred to form a suspension, then the suspension is heated to a set temperature and kept constant, and then 10BF3 is added to the suspension. …”
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3119
Correlation Between Systemic Immune Inflammatory Index and Suicidal Attempt in Patients with First-Episode Untreated Depression and its Risk Factors
Published 2025-04-01“…Yigao Wu,1,2,* Wenhao Jiang,1,* Man Chen,2 Qin Jiang,2 Huilan Huang,2 Wenbin Guo,3 Yonggui Yuan1 1Department of Psychiatry and Psychosomatics, Zhongda Hospital, School of Medicine, Jiangsu Provincial Key Laboratory of Brain Science and Medicine, Southeast University, Nanjing, People’s Republic of China; 2Department of Medical Psychology, The First Affiliated Hospital of Wannan Medical College, Wuhu, People’s Republic of China; 3Department of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yonggui Yuan, Department of Psychiatry and Psychosomatics, ZhongDa Hospital, School of Medicine, Jiangsu Provincial Key Laboratory of Brain Science and Medicine, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing, 210009, People’s Republic of China, Tel +86-025-83285124, Email yygylh2000@sina.comObjective: To examine the relationship between the systemic immune inflammatory index (SII) and suicide attempts (SA) in individuals experiencing their first episode of major depressive disorder (MDD).Methods: A retrospective analysis of 338 MDD patients (2020– 2023) at the First Affiliated Hospital of Wannan Medical College and 76 healthy controls (HC) was conducted. …”
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3120
Association and Predictive Ability between Inflammatory Burden Index and Fever Following Endobronchial Forceps Biopsy in Lung Cancer Patients
Published 2025-05-01“…Then, the most influential factors were selected through the application of Boruta algorithm and LASSO regression method and nomogram model was developed using multivariate logistic regression. …”
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