Neutrophil elastase inhibitor (Sivelestat) in the treatment of acute respiratory distress syndrome induced by COVID-19: a multicenter retrospective cohort study by Yuting Li, Jianjun Zhao, Jiahui Wei, Yanhong Zhang, Haitao Zhang, Ying Li, Ting Liao, Yang Hu, Bo Yuan, Xinmei Zhang, Wanyan Liu, Changgang Liu, Qingsong Cui, Shunzi Wu, Hongmei Jiang, Wenge Liu, Weiheng Liu, Hongguang Xu, Gang Li, Yuyan Cai, Liting Chen, Bingwei Chen, Dong Zhang

Get full text

Discontinuation of immune checkpoint inhibitors for reasons other than disease progression and the impact on relapse and survival of advanced melanoma patients. A systematic review... by Konstantinos Lallas, Eftychia Chatziioannou, Derya Durak, Georg Frey, Lina Maria Serna-Higuita, Marie-Lena Rasch, Athanassios Kyrgidis, Eleni Timotheadou, Zoe Apalla, Ulrike Leiter, Lukas Flatz, Lukas Flatz, Aimilios Lallas, Teresa Amaral, Teresa Amaral

Get full text

Rationale and design of a multicentre randomised controlled trial on circulating tumour DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer (CINTS-R) by Bin Wu, Yi Xiao, Xiao Zhang, Tao Xu, Qian Liu, Wei Fu, Yang An, Yongheng Li, Guole Lin, Huadan Xue, Guoju Wu, Jiaolin Zhou, Hongwei Yao, Zhenjun Wang, Weijie Chen, Junyang Lu, Guannan Zhang, Xiaoyuan Qiu

Get full text

Supervised Injecting Room Cohort Study (SIRX): study protocol by Lisa Maher, Thomas Kerr, Matthew Hickman, Alexander Thompson, Peter Higgs, Paul Dietze, Paul A Agius, Nick Scott, Daniel O’Keefe, Mark A Stoové, Jack Stone, Dylan Vella-Horne, Ashleigh C Stewart, Amanda Roxburgh, Sione Crawford, Josephine Norman, Zachary Lloyd, Nico Clark

Get full text

Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa by Katrien F.M. Bracké, Laura Monteiro Rente Dias, Marisha N. Meijer, Cathelijne P.M. Steegers, Laurinde F. den Heijer, Tess van der Harst, Marjolein H.G. Dremmen, Meike W. Vernooij, Gwen C. Dieleman, Tonya White

Get full text

Nurses' self-efficacy and outcome expectancy in evidence-based practice: Translation, construct validity and internal consistency of the Dutch scales by Peter Hoegen, Michael Echteld, Cindy de Bot, Annemarie de Vos, Derya Demirçay, Mary-Anne Ramis, Lidwine Mokkink, Hester Vermeulen

Get full text

Detection of antimicrobial resistance in Glaesserella parasuis in South China using whole-genome sequencing by Qianwen Ge, Qianwen Ge, Liangxing Fang, Liangxing Fang, Liangxing Fang, Yang Yu, Yang Yu, Yang Yu, Ruanyang Sun, Ruanyang Sun, Xiaoping Liao, Xiaoping Liao, Xiaoping Liao, Peng Zhang, Peng Zhang, Peng Zhang

“…Group 1 vtaA genes were detected in 87.5% (n = 42) of the isolates.ConclusionThis study provides comprehensive insights into the molecular mechanisms responsible for drug resistance in G. parasuis, the characteristics of molecular epidemiology, and the virulence of resistant groups. …”
Get full text

Critical review of multimorbidity outcome measures suitable for low-income and middle-income country settings: perspectives from the Global Alliance for Chronic Diseases (GACD) res... by Najma Siddiqi, Meena Daivadanam, J Jaime Miranda, Trishul Siddharthan, John R Hurst, Rajesh Vedanthan, Gary Parker, Gina Agarwal, Shabbar Jaffar, Naomi Levitt, Niels H Chavannes, Pallab K Maulik, Patricio Lopez-Jaramillo, Kamran Siddiqi, Muralidhar M Kulkarni, Gillian Sandra Gould, Job F M van Boven, Kirsten Bobrow, M O Owolabi, Joan B Soriano, Erick Wan-Chun Huang, Shahirose Sadrudin Premji, Lijing Yan, Ricardo Araya, F Xavier Gómez-Olivé, Bruce J Kirenga, Rianne M J J van der Kleij, Laura Loli-Dano, Shane Norris, Josefien van Olmen, Antigona C Trofor

Get full text

Collagen turnover biomarkers to predict outcome of patients with biliary cancer by Leonard Kaps, Muhammed A. Genc, Markus Moehler, Stephan Grabbe, Jörn M. Schattenberg, Detlef Schuppan, Rasmus Sund Pedersen, Morten A. Karsdal, Philipp Mildenberger, Annett Maderer, Nicholas Willumsen

Get full text

Assessment of various etiological factors for oral squamous cell carcinoma in non-habit patients- a cross sectional case control study by Mudiyayirakkani Muthusamy, Pratibha Ramani, Paramasivam Arumugam, Parthiban Rudrapathy, Boopathi Kangusamy, Vishnu Priya Veeraraghavan, Selvaraj Jayaraman, Balachander Kannan, Anitha Pandi

Get full text

Comparison of fluorescence in situ hybridization (FISH) and urine cytology in diagnosing urothelial carcinoma: a single-center retrospective cohort study by WANG Zhiting, ZHU Xiaoli

“…The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist and Standards for Reporting of Diagnostic Accuracy (STARD) were followed for this study. …”
Get full text

High prevalence of overweight/obesity and central obesity among women in a rural district of Nepal in 2012–2013: a population-based study by Chandra Yogal, Chandra Yogal, Astrid Kamilla Stunes, Astrid Kamilla Stunes, Sunila Shakya, Biraj Karmarcharya, Rajendra Koju, Mats P. Mosti, Mats P. Mosti, Miriam K. Gustafsson, Miriam K. Gustafsson, Bjørn Olav Åsvold, Bjørn Olav Åsvold, Berit Schei, Unni Syversen, Unni Syversen

Get full text

Study of the effectiveness of vacuum-aspiration breast biopsy in patients with complete clinical response after neoadjuvant polychemotherapy in complex treatment of breast cancer by K. V. Maksimov, D. V. Bagdasarova, A. D. Zikiryakhodzhaev, A. A. Kolomeytseva, M. L. Mazo, V. S. Surkova, F. N. Usov, I. A. Eremeeva, A. N. Gerasimov

Get full text

Association between maternal infertility treatment and child neurodevelopment: findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study in Miyagi a... by Mami Ishikuro, Shinichi Kuriyama, Shigeo Kure, Junichi Sugawara, Taku Obara, Nobuo Yaegashi, Tatsui Otsuka, Aoi Noda, Keiko Murakami, Fumihiko Ueno, Fumiko Matsuzaki, Tomomi Onuma, Zen Watanabe, Naomi Shiga, Noriyuki Iwama, Hamada Hirotaka, Masahito Tachibana, Hiroaki Tomita, Masatoshi Saito

Get full text

Identification of the optimal candidates to benefit from surgery and chemotherapy among elderly female breast cancer patients with bone metastases by Yuchen Hu, Junfeng Tang, Xiaofeng Liu, Yusheng Sun, Baojun Gong, Qing Gao

“…Elderly female breast cancer patients with bone metastases from the Surveillance, Epidemiology, and End Results (SEER) database were included in this study and categorized into a training cohort and a validation cohort using R software. …”
Get full text

Posttraumatic Stress Disorder Is Associated With Endothelial Dysfunction in Women With HIV by Nishant Vatsa, MD, Alireza Rahbar, MD, Tanveer Kauser, MPH, Ariel Kirksey, BS, Daniel A. Gold, MD, Vardhmaan Jain, MD, Matthew E. Gold, MD, Heqiong Wang, MD, MPH, Christina Mehta, PhD, MSPH, Caitlin A. Moran, MD, Alicia K. Smith, PhD, Kimbi Hagen, EdD, Med, Ighovwerha Ofotokun, MD, MSc, Cecile D. Lahiri, MD, MS, Laurence Sperling, MD, Viola Vaccarino, MD, PhD, Puja K. Mehta, MD, Arshed A. Quyyumi, MD, Gretchen N. Neigh, PhD, Vasiliki Michopoulos, PhD

Get full text

A protocol for mobilising novel finance models for collaborative health promotion and disease prevention initiatives: taking a smart capacitating investment approach in the Invest4... by Joanna Lane, Joanna Lane, Rhiannon T. Edwards, Balázs Babarczy, Holly Whiteley, Vidya Oruganti, Vidya Oruganti, Maureen Rutten-van Mölken, Caroline Costongs, Anant R. Jani, Sarah Wordsworth, Alison Maassen, Apostolos Tsiachristas, Jacob Davies, Bengt Stavenow, Jolanda van Vliet, Steve Wright, Steve Wright, Lina Papartyte, Jennifer Catherine Camaradou, Rositsa Koleva-Kolarova

“…Here we take that idea further by exploring the applicability of SCI to public health financing to improve population health and well-being.AimTo explore and develop innovative SCI models and tools that enable collaboration and investment across health ecosystems for enhanced health promotion and disease prevention, test them in diverse real-world settings, and create a roadmap for large-scale implementation.MethodsThe Invest4Health (I4H) project brings together transdisciplinary expertise in epidemiology, public health, health economics, population science, business management, finance, implementation and social sciences, digital health innovation, and regional health systems. …”
Get full text

Clinical risk score to predict in-hospital mortality in COVID-19 patients: a retrospective cohort study by Adriano Peris, Andrea Ungar, Niccolò Marchionni, Federico Lavorini, Alessandro Bartoloni, Stefano Fumagalli, Rossella Marcucci, Giulia Cesaroni, Riccardo Pini, Carlo Nozzoli, Carlo Fumagalli, Renzo Rozzini, Matteo Vannini, Flaminia Coccia, Francesca Mazzeo, Maria Cola, Paolo Fontanari, Alessandro Morettini, Filippo Pieralli, Loredana Poggesi

Get full text

Inappropriate medication prescribing, polypharmacy, potential drug-drug interactions and medication regimen complexity in older adults attending three referral hospitals in Asmara,... by Nuru Abdu, Saleh Idrisnur, Hanae Said, Lude Kifle, Natnael Habte, Semira Ghirmai, Tomas Tewelde, Senai Mihreteab Siele, Eyasu H. Tesfamariam

Get full text

Parsing the heterogeneity of depression: a data-driven subgroup derived from cognitive function by Chenyang Xu, Yanbao Tao, Yunhan Lin, Jiahui Zhu, Zhuoran Li, Jiayi Li, Mingqia Wang, Tao Huang, Chuan Shi

Get full text