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Understanding the role of electrostatic force, van der Waals force, and osmotic pressure in retinal function and barrier integrity
Published 2025-02-01“…Among these forces, electrostatic forces play a crucial role, working alongside van der Waals forces and oncotic pressure to maintain the retina’s attachment to the RPE and ensure the integrity of the blood-retina barrier (BRB). …”
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Lactic Acid Bacteria Synergy: Electrostatic Spraying, Dipping, and Formulation Applications of Lactobacillus salivarius L28 and Enterococcus faecium J19 to Enhance Cheese Safety Ag...
Published 2025-05-01“…We hypothesized that a lactic acid bacteria (LAB) intervention applied onto the surface of cheese by electrostatic spray, dipping or formulation of the product with LAB would be effective in controlling L monocytogenes growth during refrigerated storage. …”
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Optimization and predictive modelling for the diameter of nylon-6,6 nanofibers via electrospinning for coronavirus face masks
Published 2021-11-01“…Currently, the only widely available tool for controlling the SARS-CoV-2 pandemic is nonpharmacological interventions (NPIs). Coronavirus aerosols are around 0.3–2 µm in diameter (0.9 m in mass). …”
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Nebulisation of receptor-targeted nanocomplexes for gene delivery to the airway epithelium.
Published 2011-01-01“…<h4>Conclusions</h4>RTNs showed their ability at delivering genes via nebulisation, thus suggesting their potential applications for therapeutic interventions of cystic fibrosis and other respiratory disorders.…”
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Harnessing biochar for nitrate removal from contaminated soil and water environments: Economic implications, practical feasibility, and future perspectives
Published 2025-08-01“…Lastly, this study recommends policy interventions for biochar applications for nutrient management and environmental sustainability in the agricultural sector. …”
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ANN-QSAR, Molecular Docking, ADMET Predictions, and Molecular Dynamics Studies of Isothiazole Derivatives to Design New and Selective Inhibitors of HCV Polymerase NS5B
Published 2024-12-01“…<b>Background/Objectives:</b> RNA polymerase (NS5B), serves as a crucial target for pharmaceutical interventions aimed at combating the hepatitis C virus (HCV), which poses significant health challenges worldwide. …”
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Design and screening of novel 1,2,4-Triazole-3-thione derivatives as DCN1 inhibitors for anticardiac fibrosis based on 3D-QSAR modeling and molecular dynamics
Published 2025-06-01“…As a key modulator of anticardiac fibrosis, DCN1 has emerged as an attractive target for therapeutic intervention. The aim of this study is to design and evaluate novel DCN1 inhibitors using a combination of three-dimensional quantitative structure-activity relationship (3D-QSAR) modeling, molecular docking, and molecular dynamics simulations.MethodsA dataset of 47 derivatives was employed to construct Comparative Molecular Field Analysis (COMSIA) model, incorporating steric, electrostatic, hydrophobic, hydrogen bond donor, and acceptor fields to accurately predict compound activity. …”
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Ultra-sensitive dengue NS1 protein detection via asymmetric source-drain, heterojunction and dual-dielectric cavities in a uniform tunnel FET biosensor
Published 2024-12-01“…The roles of Tunnel Gate (TG) and Auxiliary Gate (AG) are studied in terms of band energy, electric field, electrostatic potential, and other sensitivity parameters. …”
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Zwitterionic chitosan-modified amorphous ZnCuAl-LDH eye drops for efficient treatment of bacterial keratitis
Published 2025-08-01“…Notably, ZC@a-LDH antibacterial eye drops demonstrate effective intervention in bacterial keratitis in mice, outperforming the conventional tobramycin in therapeutic efficacy.…”
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Natural small molecule smart hydrogels inhibited the Hsp90/NF‐κB signaling axis in inflammation to achieve sustained antipyretic effect
Published 2025-07-01“…It is mainly governed by hydrogen bonds and electrostatic interactions. For cell bioavailability, there were substantial discrepancies between the PE-GA hydrogel and free PE at 72 and 84 h. …”
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Multidimensional treatment of periprosthetic joint infection using fusion peptide-grafted chitosan coated porous tantalum scaffold
Published 2025-02-01“…Notably, the conditioned medium intervention experiments of HUVECs and BMSCs showed that the implants had good angiogenic-osteogenic coupling properties. …”
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The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering C...
Published 2025-05-01“…<b>Background:</b> Chronic atrophic gastritis precancerous lesions (PL-CAG) are characterized by the atrophy of gastric mucosal glands, often accompanied by intestinal metaplasia or dysplasia. Timely intervention and treatment can effectively reverse its malignant progression and prevent the onset of gastric cancer. …”
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Construction of Cationic Carbon Dots Carrying Survivin siRNA Delivery System and Its Active Targeting Therapy for Liver Cancer
Published 2025-05-01“…Wenqiang Xue,1,&ast; Jinglei Du,2,&ast; Yingying Wei,2 Shizhao Zhou,2 Shicai Wang,4 Yongzhen Yang,3 Lin Chen,3 Shiping Yu2 1Department of Interventional Therapy, Shanxi Provincial People’s Hospital, Taiyuan, 030001, People’s Republic of China; 2Department of Interventional Therapy, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/ Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, 030001, People’s Republic of China; 3Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan, 030024, People’s Republic of China; 4Department of Interventional Therapy, Taiyuan Central Hospital, Taiyuan, 030001, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yongzhen Yang, Key Laboratory of Interface Science and Engineering in Advanced Materials, Ministry of Education, Taiyuan University of Technology, Taiyuan, 030024, People’s Republic of China, Email yangyongzhen@tyut.edu.cn Shiping Yu, Department of Interventional Therapy, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, 030001, People’s Republic of China, Email yushiping@sxmu.edu.cnBackground: Small interfering RNA (siRNA) provides a new method for anti-tumor therapy by targeting Survivin gene in liver cancer. …”
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Enhancing bloodstream infection diagnostics: a novel filtration and targeted next-generation sequencing approach for precise pathogen identification
Published 2025-03-01“…Such delays and inaccuracies can critically impede timely clinical interventions, potentially compromising patient outcomes. …”
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