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RETRACTED: Modern Subtype Classification and Outlier Detection Using the Attention Embedder to Transform Ovarian Cancer Diagnosis
Published 2024-01-01“…The dataset includes a wide range of images, such as tissue microarray (TMA) images at 40× magnification and whole-slide images (WSI) at 20× magnification. …”
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222
Uncovering genetic contributors to developmental delay and intellectual disability: a focus on CNVs in pediatric patients
Published 2025-06-01“…BackgroundDevelopmental delay (DD) and intellectual disability (ID) are prevalent in children and often have genetic causes, particularly copy number variations (CNVs). Chromosomal microarray analysis (CMA) and whole-exome sequencing (WES) are key diagnostic tools for identifying genetic contributions to these disorders. …”
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223
Identification of genes and pathways related to lymphovascular invasion in breast cancer patients: A bioinformatics analysis of gene expression profiles
Published 2017-06-01“…Surgery is the most effective treatment for breast cancer patients. However, some patients developed recurrence and distant metastasis after surgery. …”
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224
Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.
Published 2012-01-01“…Transcriptional profiling by cDNA microarray combined with reverse genetics revealed phosphorylation of the eukaryotic initiation factor 2-alpha (EIF2A) through the eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3/PERK) as the mechanism of action of this compound. …”
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225
Genomic copy number variants: evidence for association with antibody response to anthrax vaccine adsorbed.
Published 2013-01-01“…Anthrax vaccine is highly effective, but vaccine-induced IgG antibody responses vary widely following required doses of vaccinations. …”
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226
Homeobox protein B6 and homeobox protein B8 control immune-cancer cell interactions in pancreatic cancer
Published 2025-07-01“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer lacking effective drugs and therefore new treatment targets are needed. …”
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227
Upregulation of RIG‐I is Critical for Responsiveness to IFN‐α Plus Anti‐PD‐1 in Colorectal Cancer
Published 2025-03-01“…ABSTRACT Backgrounds Immunotherapy is a promising and effective approach that has achieved significant curative effects in colorectal cancer (CRC). …”
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228
Altered expression of miRNA profile in peripheral blood mononuclear cells following the third dose of inactivated COVID-19 vaccine
Published 2025-01-01“…COVID-19 vaccination is the most effective strategy for preventing severe disease and death. …”
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229
Mutation spectrum in epilepsy and seizure disorders in a group of Emirati patients: a retrospective cohort study and literature review
Published 2025-07-01“…The genetic tests were performed based on the patient's clinical phenotypes and family history, and included chromosome microarray, targeted variant testing, next-generation sequencing, or whole-exome sequencing (solo or trio). …”
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230
USP5 Promotes Head and Neck Squamous Cell Carcinoma Progression via mTOR Signaling Pathway
Published 2025-03-01“…Validation was conducted using tissue microarray (TMA) analysis and immunohistochemistry (IHC) to compare USP5 expression levels in HNSCC tissues versus adjacent normal tissues. …”
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231
Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury
Published 2025-01-01“…Methods We employed microarray and single-cell RNA sequencing (scRNA-seq) to investigate gene expression changes and immune cell dynamics in mice following crush injury at 3 and 7 days post-injury (dpi). …”
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232
Hypoxia alters the response of ovarian cancer cells to the mitomycin C drug
Published 2025-06-01“…In this study, we show that mitomycin C (MMC), an antineoplastic antibiotic, is rarely used in ovarian cancer (OC) treatment despite its potential efficacy; we use MMC as an example of a treatment that warrants reevaluation under microenvironmental conditions, particularly during in vitro testing.MethodsTo evaluate the effects of MMC and oxygen tension (pO2) on OC cells (SKOV3), HTA 2.0 microarrays were used, which demonstrated that hypoxia and MMC induced transcriptomic changes in OC cells. …”
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233
Efficacy and tolerability of rufinamide in the treatment of epilepsy (experience of the Svt. Luka’s Institute of Child Neurology and Epilepsy)
Published 2018-11-01“…Side effects were observed in 6 (19 %) participants. Side effects (forced normalization) caused withdrawal of rufinamide in 1 (3.2 %) patient. …”
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234
Transcriptional response to deletion of the phosphatidylserine decarboxylase Psd1p in the yeast Saccharomyces cerevisiae.
Published 2013-01-01“…To study the genome wide effect of an unbalanced cellular and mitochondrial PE level and in particular the contribution of Psd1p to this depletion we performed a DNA microarray analysis with a ∆psd1 deletion mutant. …”
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235
Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers.
Published 2016-01-01“…A microarray of cyotoskeleton regulators was probed to examine differences in gene expression between cells grown on an aligned and randomly oriented substrates. …”
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236
Nanomaterials based biosensors applied for detection of aflatoxin B1 in cereals: a review
Published 2025-01-01“…It causes immune-suppressive effects, raising the risk of mutagenicity, carcinogenicity, teratogenicity, hepatotoxicity, and embryonic toxicity, as well as increasing illness and death. …”
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237
Establishing an induced pluripotent stem cell bank using urine cells from pediatric patients with neurogenetic diseases
Published 2025-08-01“…The genomic stability of the iPSCs was assessed using chromosomal microarray (CMA). Results UCs were successfully isolated from patients with various early-onset neurogenetic diseases and reprogrammed into iPSCs. …”
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238
Genetic test results and one-year developmental outcomes of fetuses with congenital heart disease
Published 2025-03-01“…ObjectiveThis study evaluated the utility of single nucleotide polymorphism (SNP) microarray analysis in prenatal genetic assessment of fetuses diagnosed with congenital heart disease (CHD), retrospectively analyzing pregnancy outcomes and their association with physical and intellectual development within the first year of life.Patients and methodsIt included 105 fetuses diagnosed with CHD via prenatal echocardiography from January 2016 to June 2020, categorized into two groups: isolated cardiac structural abnormalities (76 cases) and additional extracardiac structural abnormalities (29 cases). …”
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239
The Functions and Mechanism of a New Oligopeptide BP9 from Avian Bursa on Antibody Responses, Immature B Cell, and Autophagy
Published 2019-01-01“…These results suggested that BP9 might be a strong bursal-derived active peptide on antibody response, B cell differentiation, and autophagy in immature B cells, which provided the linking among humoral immunity, B cell differentiation, and autophagy and offered the important reference for the effective immunotherapeutic strategies and immune improvement.…”
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240
Integrated analysis of hub genes and intrinsically disordered regions in triple-negative breast cancer
Published 2024-12-01“…Two microarray datasets were used to identify possible targets for TNBC, GSE38959 and GSE45827, retrieved from the Gene Expression Omnibus (GEO) database. …”
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