Effects of SNX9 on the structure and function of primary cilia in autosomal dominant polycystic kidney disease by Shen Ai-wen, Hu Wan-qian, Lin Lu, Yu Sheng-qiang

“…Objective To explore the effect and mechanism of SNX9 on primary cilia in autosomal dominant polycystic kidney disease（ADPKD）and provide theoretical rationales for seeking intervention targets.Methods The localization of SNX9 in cystic lining epithelium cell line（WT9-12）was observed by immunofluorescence.And the differential expression of SNX9 between normal renal tubular epithelial cell line（RCTEC）and WT9-12 was detected by Western blot.The expression of IFT88 was detected by Western blot and the change of cilia length examined by immunofluorescence.Results SNX9 existed in both cytoplasm and membrane of WT9-12 and its expression was lower than that in RCTEC（P<0.05）.When the expression of SNX9 was down-regulated,the expression of IFT88 declined and cilia became shorter（P<0.05）.Meanwhile,after the up-regulation of SNX9 by lentivirus,the expression of IFT88 increased and cilia became longer（P<0.01）.Conclusions In ADPKD,SNX9 exists in both membrane and cytoplasm of cyst epithelium and its expression is lower than that of normal renal tubular epithelial cell.As a result,the morphology and function of primary cilia become compromised.An up-regulation of SNX9 preserves the function of primary cilia and it may become a new target for ADPKD therapy.…”
Get full text

The Acute Effects of Low-Dose TNF-α on Glucose Metabolism and β-Cell Function in Humans by Tobias Ibfelt, Christian P. Fischer, Peter Plomgaard, Gerrit van Hall, Bente Klarlund Pedersen

Get full text

The Effect of TRX Training with Avodin Supplement on Biochemical Factors and Renal Function in Patients with Rheumatoid Arthritis by SH Eskandari, H Sheikhani Shahin, M Moghadasi

“…Therefore, the present study investigated the effect of TRX exercises with the addition of avodin on biochemical factors and renal function in patients with RA. …”
Get full text

Functional effects of operations for malignant gastric neoplasms: prevention, diagnosis and treatment of post-gastrectomy disorders by A. V. Chaika, V. M. Khomyakov, A. B. Ryabov

Get full text

The effect of extreme loads on changes in accuracy of the throw and functional indicators of heart rate in handball players by Nikiforova, Olga N., Markin, Edward V.

Get full text

The Effects of Multicomponent Training on Clinical, Functional, and Psychological Outcomes in Cardiovascular Disease: A Narrative Review by Luca Poli, Alessandro Petrelli, Francesco Fischetti, Stefania Morsanuto, Livica Talaba, Stefania Cataldi, Gianpiero Greco

Get full text

Effects of Spinal Decompression and Segmental Spinal Instrumentation on Lower Limb Functionality in Patients with Spinal Osteoarthritis by Milan Mirković, Filip Kukić, Dragan Mirkov, Dejan Marinković, Lazar Mičeta, Sanja Mirković, Biljana Božić Nedeljković, Zoran Baščarević

“…Treatment primarily aims to improve functionality and quality of life. This study investigated the effects of lower back surgery (e.g., spinal decompression with vertebra stabilization) on upper-limb maximum strength, lower limb functionality, and quality of life in osteoarthritis patients. …”
Get full text

Effects of different anesthetic methods on immune function and oxidative stress in patients undergoing laparoscopic herniorrhaphy by Lei Wu, Jingying Liu, Yue Chen, Lei Tan, Qiannan Fan, Mingjie Zhong, Hao Wu

Get full text

Effects of different functional fertilizers on quality, yield and substrate environment of substrate-grown cherry tomatoes by TAN Hongji, GAO Yanming, LI Jianshe, WEI Wenlu

“…The functional fertilizers and nutrient solution were applied by drip irrigation to study the effects of different functional fertilizers on quality, yield and substrate environment of substrate-grown cherry tomatoes. …”
Get full text

Effects of environmental heterogeneity on fish biodiversity and ecosystem functioning (BEF) relationships in the Yangtze River, China by Chang Xie, Jishun Ma, Hongwei Yao, Jun Wang, Qiong Zhou

“…Specifically, how environmental heterogeneity shapes the effects of biodiversity on aquatic ecosystem functioning has been rarely researched. …”
Get full text

Evaluation of the effects of group psychotherapy on cognitive function in patients with multiple sclerosis with cognitive dysfunction and depression by Emine Bilgi, Hasan Hüseyin Özdemir, Ayhan Bingol, Serpil Bulut

Get full text

Effects of lymphedema on posture, upper extremity functions, and quality of life in patients with unilateral breast cancer by Turan Simla, Çil Elif Tuğçe, Subaşı Feryal, Aksoy Fikret

“…This study aimed to examine the effects of lymphedema on upper extremity function, posture and quality of life in patients with upper extremity lymphedema after unilateral breast cancer.…”
Get full text

Effect of Ultrasonic Intensity Treatment on the Physicochemical and Functional Properties of <i>Coregonus peled</i> Protamine by Feifei Wang, Dong Shu, Yabo Wei, Xin Guo, Pingping Liu, Xiaorong Deng, Yunfeng Zhao, Yongdong Lei, Jian Zhang

“…As the most valuable protein in the sperm of testes tissues of <i>Coregonus peled</i>, <i>Coregonus peled</i> protamine (CPP) had a natural antibacterial and antiseptic effect, but its physicochemical properties and functions are easily affected by the ultrasound-assisted extraction process. …”
Get full text

Functionalities of Octenyl Succinic Anhydride Wheat Starch and Its Effect on the Quality of Model Dough and Noodles by Hongxue Ma, Liai Yang, Dunhe Zhang, Huijing Chen, Jianquan Kan

“…Chemically modified starch is a widely used food additive for tailoring the quality of wheat flour products. However, the effects of octenyl succinic anhydride (OSA)-modified wheat starch with varying degrees of substitution on the quality of dough and noodles remain unclear. …”
Get full text

Effects of Mulberry Leaf Extract on the Liver Function of Juvenile Spotted Sea Bass (Lateolabrax maculatus) by Sishun Zhou, Hao Lin, Lumin Kong, Jianrong Ma, Zhongying Long, Huihui Qin, Zhangfan Huang, Yi Lin, Longhui Liu, Zhongbao Li

“…This study provides a theoretical basis for the application of ELM in the cultivation of spotted sea bass by exploring the effect of ELM on the liver function of spotted sea bass.…”
Get full text

Effects of nanosilicate functionalized polycaprolactone membrane on bone mesenchymal stem cells-induced bone repairing by XIAO Long, HU Weiqiang, LIN Xuxin, HE Mengjiao, LUO Kai, XU Xiongcheng

Get full text

Effect of SkQ1 Antioxidant on Structural and Functional Conditions of The Brain in PostResuscitation Period by M. L. Lovat, M. Sh. Avrushchenko, O. A. Averina, V. V. Pavshintsev, I. V. Ostrova, Y. V. Zarzhetsky, V. V. Moroz, M. V. Egorov

“…Data confirm the positive effects of SkQ1 on structural and functional status of the brain postre suscitation and suggest possible use of SkQ1 for the prevention or correction of posthypoxic encephalopathies.…”
Get full text

Functional and microbiological effects of a microencapsulated probiotic consortium on the ruminal microbiota in vivo and in vitro systems by Johanna Marcela Urán Velásquez, Mauricio Agudelo Rendón, Mariana Zapata, Wilyer García Arboleda, Sara Echeverri, Juan Camilo Arroyave Manco, Koen Venema, Juan Vasquez

“…The use of microencapsulated probiotics induced both taxonomic and functional changes in the initial microbial community of the IVT and IVV systems, which can be linked to the zootechnical effects of using probiotics as additives in ruminal animal nutrition.…”
Get full text

Effects of exogenous chitosan concentrations on photosynthesis and functional physiological traits of hibiscus under salt stress by Yangfan Cao, Ruiyang Yan, Mingcong Sun, Jing Guo, Shuyong Zhang

Get full text

Effect of Elastically Restrained Edges on Free Transverse Vibration of Functionally Graded Porous Rectangular Plate by Yajuvindra Kumar

“…In this paper, the author studied free transverse vibration of a thin isotropic simply-supported functionally graded (FG) rectangular plate with porosity effect based on classical plate theory. …”
Get full text