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    Effect of Aerobic Treadmill Exercise Regulating Glucose Transporter 9 on Renal Function in Hyperuricemia Rats by LIANG Jiarong, YANG Huan, CUN Yongdan, WANG Lihuan, LI Yijie, YE Bin

    Published 2022-04-01
    “…Hematoxylin-eosin (HE) was used to stain the renal histopathological section, and the microscope (×400) was used to observe the structural changes of renal tubules and glomerulus; the peroxidase method was used to detect the renal function indexes such as uric acid (UA), creatinine (Cre) and urea nitrogen (BUN); enzyme-linked immunosorbent assay (ELISA) method was used to determine the contents of interleukin-1β (IL-1β) in serum and kidney tissues; Western blot was used to detect the expressions of Caspase-1, IL-1β and glucose transporter 9 (GLUT-9) in the kidney tissues.Results① Pathological examination results: there was not obvious pathological changes were observed in the kidney tissues of the Control group; in the Model group, the renal tissue capsule was incomplete, the glomerulus was deformed and atrophic, and the renal tubules were disordered; in the Exercise group, the number of inflammatory cell infiltration was significantly decreased, the renal tubular structure was relatively intact, and the pathological changes such as cytoplasmic vacuolation of renal tubular epithelial cells were significantly decreased. ② UA, Cre and BUN content of serum: compared with the Control group, UA, BUN and Cre content in serum of the Model group and Exercise group was significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, UA, BUN and Cre content in serum of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05). ③ Serum and kidney IL-1β content: compared with the Control group, the expression of IL-1β in serum and kidney of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expression of IL-1β in serum and kidney of the Exercise group was significantly decreased (<italic>P</italic>&lt;0.05). ④ Expressions of Caspase-1, IL-1β and GLUT-9 protein: compared with the Control group, the expressions of Caspase-1, IL-1β and GLUT-9 protein in kidney tissues of the Model group and the Exercise group were significantly increased (<italic>P</italic>&lt;0.05); compared with the Model group, the expressions of Caspase-1, IL-1β, and GLUT-9 protein in kidney tissues of the Exercise group were significantly decreased (<italic>P</italic>&lt;0.05).ConclusionAerobic treadmill exercise can effectively reduce the level of uric acid and inflammatory response of hyperuricemia rats, and improve renal function, which may be related to the regulation of GLUT-9 protein expression.…”
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    Effects of external diaphragmatic pacing with neurally adjusted ventilatory assist on diaphragm function in AECOPD patients by Yuliang Sheng, Ting Wang, Xiaohan Zhang, Wei Shao, Yuhao Wang, Xiuwen Kang, Caihong Gu, Yong Li, Zhifang Mu, Chenying Zhang, Rong Hu

    Published 2025-06-01
    “…The primary outcome was diaphragmatic function, assessed using two ultrasonographic parameters: diaphragmatic excursion (DE) and diaphragm thickness fraction (DTF). …”
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  8. 1088

    Physicochemical and Functional Value of Lettuce: Effect of Mulching Technique Used During Production on Postharvest Storage by Roxana E. González, Melisa Lanza Volpe, Verónica C. Soto Vargas

    Published 2025-01-01
    “…The aim of our work was to evaluate the effect of different mulching techniques and test their effect on the morpho-physiological performance and nutritive value of Iceberg lettuce plants, and their changes during postharvest storage. …”
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    The effect of structural defects on the electron transport of MoS2 nanoribbons based on density functional theory by Farahnaz Zakerian, Morteza Fathipour, Rahim Faez, Ghafar Darvish

    Published 2019-02-01
    “…Abstract Using non-equilibrium Green’s function method and density functional theory, we study the effect of line structural defects on the electron transport of zigzag molybdenum disulfide (MoS2) nanoribbons. …”
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  10. 1090

    Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia by Mengying Zheng, Bingnan Liu, Yuanyuan Shao, Luogang Hua, Rong Fu, Huaquan Wang, Ting Wang, Weiwei Qi, Zonghong Shao, Chunyan Liu

    Published 2020-01-01
    “…This study is aimed at investigating the effects of shikonin, a pyruvate kinase M2 (PKM2) inhibitor, on the functions of myeloid dendritic cells (mDCs) in a mouse model of severe aplastic anemia (AA) generated by total body irradiation and lymphocyte infusion. …”
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    The Effect of Selected Exercise Group on Motor Skills and Cognitive Functions in Children With Autism Spectrum Disorders by Mahbubeh Ghayour Najafabadi, Amir Sobh-Rhakhshankhah, Sepideh Niyazi

    Published 2019-07-01
    “…Introduction: The present study aimed to determine the effects of a selected group exercise on motor skills and cognitive function in children with Autism Spectrum Disorders (ASDs).Methods: Forty children with ASD aged 5-12 years participated in this quasi-experimental study. …”
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    Effects of Gallic Acid on In Vitro Ruminal Fermentation, Methane Emission, Microbial Composition, and Metabolic Functions by Wei Zhu, Jianjun Guo, Xin Li, Yan Li, Lianjie Song, Yunfei Li, Baoshan Feng, Xingnan Bao, Jianguo Li, Yanxia Gao, Hongjian Xu

    Published 2025-07-01
    “…The objective of this study was to assess the effects of gallic acid (GA) on nutrient degradability, gas production, rumen fermentation, and the microbial community and its functions using in vitro fermentation methods. …”
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    Co-Existing Nanoplastics Further Exacerbates the Effects of Triclosan on the Physiological Functions of Human Serum Albumin by Yan Bao, Yaoyao Wang, Hongbin Liu, Jing Lan, Zhicai Li, Wansong Zong, Zongshan Zhao

    Published 2025-01-01
    “…The potential health risks posed by the coexistence of nanoplastics (NPs) and triclosan (TCS) have garnered significant attention. However, the effects and underlying mechanisms of NPs and TCS on key functional proteins at the molecular level remain poorly understood. …”
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    Effects of short- and long-term plant functional group removal on alpine meadow community niche by Jingjing Wei, Zhonghua Zhang, Li Ma, Xue Hu, Haze Ade, Haze Ade, Hongye Su, Hongye Su, Zhengchen Shi, Zhengchen Shi, Honglin Li, Huakun Zhou

    Published 2024-11-01
    “…The rapid loss of global biodiversity affects the creation and maintenance of community biodiversity and ecosystem structure and function. Thus, it is insufficient to focus solely on the effects of biodiversity loss on community biodiversity without also considering other impacts such as community assembly, niches, interspecific relationships, community stability, and biodiversity–ecosystem function. …”
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    An investigation into the effect of different missing data imputation methods on IRT-based differential item functioning by Hakan Koğar, Fatma Ünal

    Published 2024-09-01
    “…The purpose of this study is to examine the effect of missing data imputation methods, namely regression imputation (RI), multiple imputation (MI) and k-nearest neighbor (kNN) on differential item functioning (DIF). …”
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    Effects of Aqueous Extracts from Wheat Bran Layers on the Functional Properties of Wheat Starch and Gluten by Bingbing Wu, Chunlei Yu, Zhongwei Chen, Bin Xu

    Published 2025-06-01
    “…The aqueous extracts reduced the storage (G′) and loss (G″) moduli of wheat gluten, primarily attributed to the effect of polysaccharide components, whereas the protein and ash fractions elevated the G′ and G″ at suitable dosages. …”
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    Evaluation of the effects of thyroid functions on frailty in geriatric patients using the Edmonton, SOF and FRAIL Scales by Galip Can Uyar, Mustafa Kemal Kılıç

    Published 2024-12-01
    “…While age-related chronic conditions have been extensively studied, the relationship between thyroid function and frailty remains underexplored. Objective This study aimed to evaluate the effects of thyroid dysfunction on frailty among individuals aged 65 years and older. …”
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