Influence of binge drinking on the resting state functional connectivity of university Students: A follow-up study by Samuel Suárez-Suárez, Fernando Cadaveira, Alfonso Barrós-Loscertales, José Manuel Pérez-García, Socorro Rodríguez Holguín, Javier Blanco-Ramos, Sonia Doallo

“…Maintaining a BD pattern during critical neurodevelopmental years impacts RS-FC, indicating mid-to-long-term alterations in functional brain organization. This study provides new insights into the neurotoxic effects of adolescent alcohol misuse, emphasizing the need for longitudinal studies addressing the lasting consequences on brain functional connectivity.…”
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Single‐microbe RNA sequencing uncovers unexplored specialized metabolic functions of keystone species in the human gut by Yifei Shen, Wenxin Qu, Mengdi Song, Tianyu Zhang, Chang Liu, Xiaofeng Shi, Xinxin Xu, Jingjing Jiang, Liguo Ding, Fangyu Mo, Zheying Mao, Mingzhu Huang, Ziye Xu, Jiaye Chen, Enhui Shen, Jian Ruan, Jiong Liu, Michael P. Timko, Yu Chen, Longjiang Fan, Shufa Zheng, Yongcheng Wang

“…As such, little is known about the species–function heterogeneity and dynamic activities in human microecosystem niches. …”
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Cognitive Function Deficits Associated With Type 2 Diabetes and Retinopathy: Volumetric Brain MR Imaging Study by Ece Ozdemir Oktem, Dila Sayman, Sevilay Ayyildiz, Çaglar Oktem, Lutfiye Ipek, Behcet Ayyildiz, Fatih Aslan, Emin Utku Altindal, Nilay Yagci, Rumeysa Dikici, Ramazan Karaca, Şeyda Cankaya, Seda Avnioglu, Halil Aziz Velioglu, Burak Yulug

“…ABSTRACT Introduction Type 2 diabetes mellitus is a ubiquitous chronic inflammatory disease with deleterious effects on various tissues, including the kidney, retina, and peripheral nerves. …”
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Impact of endoplasmic reticulum aminopeptidases 1 (ERAP1) and 2 (ERAP2) on neutrophil cellular functions by Irma Saulle, Irma Saulle, Fiona Limanaqi, Micaela Garziano, Micaela Garziano, Maria Luisa Murno, Valentina Artusa, Valentina Artusa, Sergio Strizzi, Matteo Giovarelli, Carsten Schulte, Jacopo Aiello, Mario Clerici, Mario Clerici, Claudia Vanetti, Mara Biasin

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What is the influence of exacerbations on pulmonary function in pediatric and adolescent patients with severe asthma despite controller therapies? by A. Z. P. Brandão, L. M. L. B. F. Lasmar, L. M. A. S. Pertence, M. I. R. Vieira, G. B. Lasmar, V. O. Ganem, E. V. Mancuzo, M. V. N. P. de Queiroz

“…Abstract Background Although exacerbations are common in severe asthma, there have been few longitudinal studies evaluating their effect on lung function parameters. This study aimed to evaluate the impact of exacerbations on lung function in children and adolescents with severe asthma in Brazil. …”
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Glucose absorption in the duodenum is modulated by an estrogen receptor α-dependent regulation of glucose transporter functional expression by Xiaoxu Yang, Qian Du, Rui Xie, Jianhong Ding, Weixi Shan, Jingyu Xu, Changmei Chen, Qiushi Liao, Jun Lou, Zhe Jin, Mingkai Chen

“…In this study, we investigated the effects of estrogen on glucose absorption in humans, mice, and the human intestinal epithelium cell line SCBN.Research design and methods The ovariectomized (OVX) animal model was established. …”
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Interferon-γ Signaling in Eosinophilic Esophagitis Affects Epithelial Barrier Function and Programmed Cell DeathSummary by Megha Lal, Caitlin M. Burk, Ravi Gautam, Zoe Mrozek, Karina E. Canziani, Tina Trachsel, Jarad Beers, Margaret C. Carroll, Duncan M. Morgan, Amanda B. Muir, Wayne G. Shreffler, Melanie A. Ruffner

“…The functional impact of IFN-α and IFN-γ on epithelial cells was investigated using organoid models. …”
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Altered brain glymphatic function on diffusion-tensor MRI in patients with spontaneous intracerebral hemorrhage: an exploratory study by Xiaona Xia, Qingguo Ren, Juntao Zhang, Shuai Guan, Qingjun Jiang, Ying Wei, Rui Hua, Shen Zhao, Xiangjun Hu, Xiangjun Hu, Feng Shi, Xiangshui Meng

“…In chronic sICH groups, GM% served as a significant mediator in the relationship between the DTI-ALPS index and MoCA scores (indirect effects β = 4.925, 95%CI: 0.028, 11.841). The ALPS index was identified as an independent prognostic indicator for unfavorable outcomes in sICH (β = −9.851, p = 0.018).ConclusionOur study demonstrated that the DTI-ALPS index decreased in sICH patients, suggesting potential functional impairment of the lymphoid system. …”
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IgG detection in human serum employing non-functionalized chromium doped zinc gallate nanoparticles by Zied Ferjaoui, Capucine Zimmer, Celina Matuszewska, Corinne Chanéac, Bruno Viana, Cédric Bouzigues, Daniel Scherman, Nathalie Mignet, Cyrille Richard

“…In this study, we investigated the effect of the protocol used to synthesize these ZGO nanoparticles, using a hydrothermal treatment at 220°C for different durations (6 h, 12 h, and 24 h), followed by calcination at 500°C. …”
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A decellularized flowable placental connective tissue matrix supports cellular functions of human tenocytes in vitro by Yong Mao, Nikita John, Nicole M. Protzman, Adam Kuehn, Desiree Long, Raja Sivalenka, Radoslaw A. Junka, Anna Gosiewska, Robert J. Hariri, Stephen A. Brigido

“…The purpose of this study is to evaluate the effects of placental CTMs on the cellular activities of human tenocytes. …”
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Robust computation of subcortical functional connectivity guided by quantitative susceptibility mapping: An application in Parkinson’s disease diagnosis by Jianmei Qin, Haoting Wu, Chenqing Wu, Tao Guo, Cheng Zhou, Xiaojie Duanmu, Sijia Tan, Jiaqi Wen, Qianshi Zheng, Weijin Yuan, Zihao Zhu, Jingwen Chen, Jingjing Wu, Chenyu He, Yiran Ma, Chunlei Liu, Xiaojun Xu, Xiaojun Guan, Minming Zhang

“…Previous resting state functional MRI (rs-fMRI) analyses of the basal ganglia in Parkinson’s disease heavily relied on T1-weighted imaging (T1WI) atlases. …”
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Dietary Oregano Oil Supplementation Improved Egg Quality by Altering Cecal Microbiota Function in Laying Hens by Lili Xian, Yan Wang, Da Peng, Lei Zang, Yidan Xu, Yuanyuan Wu, Jingjing Li, Jing Feng

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S100A4-shRNA mitigates autophagy, reduces inflammation, and improves cardiac functionality in MIRI by Guangwei Huang, Qing Huang, Chenrui Mou, Anna Duan, Fujiao He, Hailong Dai

“…Diagnostic procedures, including electrocardiogram assessments, cardiac function testing, cardiac enzyme analyses, and 2,3,5-triphenyl tetrazolium chloride (TTC) staining, were performed to assess myocardial injury. …”
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Tuning the d-Band Center of Nickel Bimetallic Compounds for Glycerol Chemisorption: A Density Functional Study by Carlos M. Ramos-Castillo, Luis Torres-Pacheco, Lorena Álvarez-Contreras, Noé Arjona, Minerva Guerra-Balcázar

“…This study explores the electronic factors behind the adsorption of glycerol (Gly) on bimetallic nickel-based compounds (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>Ni</mi><mn>3</mn></msub><mi mathvariant="normal">X</mi></mrow></semantics></math></inline-formula>) using density functional theory (DFT) calculations; incorporating Mn, Fe, Co, Cu, and Zn as promoters effectively tunes the d-band center of these systems, directly influencing their magnetic, adsorption, and catalytic properties. …”
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Polymer-Functionalized Magnetic Nanoparticles for Targeted Quercetin Delivery: A Potential Strategy for Colon Cancer Treatment by Júlia Borges de Macedo, Julia Narayana Schoroeder Bueno, Carla Cristine Kanunfre, José Ricardo de Arruda Miranda, Andris Figueiroa Bakuzis, Priscileila Colerato Ferrari

“…<b>Methods</b>: After FA-CS synthesis and 3² factorial design, polymer-functionalized MNPs were produced for quercetin loading, characterized, and evaluated by drug dissolution and cytotoxicity assay. …”
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Association and function analysis of genetic variants and the risk of gestational diabetes mellitus in a southern Chinese population by Qiulian Liang, Yan Sun, Ming Li, Ruiqi Li, Lijie Nie, Lin Lin, Xiangyuan Yu

“…CC: crude OR = 1.42, 95% CI: 1.08–1.86, p = 0.013). Functional analysis suggested that rs4134819 can alter the specific transcription factors (CPE bind and GATE-1) binding to the promoter of the XAB2 gene, regulating the transcription of XAB2. …”
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Metatranscriptomic analysis of colonic mucosal samples exploring the functional role of active microbial consortia in complicated diverticulitis by Brittney N. McMullen, Jeremy Chen See, Samantha Baker, Justin R. Wright, Samantha L. C. Anderson, Gregory Yochum, Walter Koltun, Austin Portolese, Nimalan A. Jeganathan, Regina Lamendella

“…It is possible clinicians could someday harness this information to more effectively treat complicated diverticulitis symptoms. …”
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A multi-function glass shield for neutrons and gamma rays of boron- and bismuth-reinforced silicate glass by Hadeer M. Nasr El Din, Aly Saeed, Eman Salem, R. M. El Shazly, Magda Abdel Wahab

“…Abstract A successful attempt to produce a multi-function glass shield for attenuating neutrons and gamma rays by reinforcing a silicate glass network with boron and bismuth has been accomplished. …”
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Association Between Fine Particle Waves and Sexual Function: A Nationwide Cross-Sectional Survey in China by Weiqian Zhang, Rui Qu, Guan Cheng, Jingxuan Wang, Tailang Yin, Jue Liu, Dongdong Tang, Yan Zhang

“…Background: The effect of the long-term persistently elevated air pollutants, often referred to as air pollution waves, on sexual function has not been sufficiently addressed. …”
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Deciphering influence of donor age on adipose-derived stem cells: in vitro paracrine function and angiogenic potential by Chloe Trotzier, Clement Bellanger, Hakima Abdessadeq, Philippe Delannoy, Ali Mojallal, Celine Auxenfans

“…Here we’ve investigated the effect of age on paracrine function, stemness and angiogenic potential of ASC. …”
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