Hybrid azole-based conjugates as upcoming anticancer and antimicrobial agents by Luís M. T. Frija, Bruno E. C. Guerreiro, Inês C. C. Costa, Vera M. S. Isca, Lucília Saraiva, Beatriz G. Neves, Mariana Magalhães, Célia Cabral, Maria L. S. Cristiano, Patrícia Rijo

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ECM1 expression in chronic liver disease: Regulation by EGF/STAT1 and IFNγ/NRF2 signalling by Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Cyrill Géraud, Lea Berger, Shanshan Wang, Ye Yao, Chenhao Tong, Claudia Rubie, Laura Kim Feiner, Zeribe C. Nwosu, Frederik Link, Pia Erdösi, Weronika Piorońska, Kerry Gould, Christoph Meyer, Rilu Feng, Hui Liu, Chen Shao, Bing Sun, Huiguo Ding, Roman Liebe, Matthias P.A. Ebert, Honglei Weng, Matthias Glanemann, Chunfang Gao, Peter ten Dijke, Steven Dooley, Sai Wang

“…Moreover, AAV8-ECM1 attenuates liver fibrosis and injury in Western diet-fed mice (n = 8–10), counteracting the effects of EGF signalling inhibition and IFNγ/NRF2 activation. …”
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Abstract 200: ICA Lesion Etiology does not affect the Outcomes after Endovascular Treatment of Acute Tandem LVO by Milagros R. Galecio Castillo, Mudassir Farooqui, Ameer Hassan, Mouhammad Jumaa, Afshin Divani, Marc Ribo, Michael Abraham, Nils Petersen, Johanna Fifi, Waldo Guerrero, Amer Malik, James Siegler, Thanh Nguyen, Sunil Sheth, Albert Yoo, Guillermo Linares, Nazli Janjua, Darko Quispe‐Orozco, Wondewossen Tekle, Syed Zahid Ali, Asad Ikram, Cynthia Zevallos, Marta Olivé‐Gadea, Abid Qureshi, Alex Devarajan, Nicholas Vigilante, Mohamad Abdalkader, Sergio Salazar‐Marioni, Jazba Soomro, Weston Gordon, Charoskhon Turabova, Juan Vivanco‐Suarez, Aaron Rodriguez‐Calienes, Maxim Mokin, Dileep Yavagal, Santiago Ortega‐Gutierrez

“…Clinical outcomes, including recanalization success, functional independence and hemorrhagic events were assessed with multivariable analyses. …”
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Safety Profile of COVID-19 Vaccines in HIV Patients Undergoing ART and Their Impact on Immune Recovery and HIV Reservoirs by Bing Song, Xinhua Wang, Lin Shen, Juan Cheng, Jing Tian, Chunjie Zhang, Zhuanghong Zhao, Yuting Zhou, Rong Liang, Zihan Zhou, Xinyi Yang, Xuhai Suo, Tianjun Jiang, Huihuang Huang, Qun Guan, Ying Yang, Bingke Bai, Haijuan Wang

“…We assessed the changes in liver and kidney functions, blood lipids, and other laboratory parameters at 0, 1, 2, 4, 7, 8, 10, and 13 months after the first vaccination dose. …”
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Jawbone mesenchymal stromal cells attenuate acute inflammation via hematopoietic niche reinforcement by Xinyu Wang, Qianye Chen, Jiping Sun, Zihan Huang, Zijian Zhang, Tingwei Lu, Xiangru Huang, Siyuan Sun, Yuanqi Liu, Houwen Pan, Li Mei, Paul R. Cooper, Qinggang Dai, Lei Shen, Lingyong Jiang

“…Although most investigations have centered on mesenchymal stem cells (MSCs) from long bones, the distinct properties and immunoregulatory functions of craniofacial bone marrow derived MSCs remain largely unexplored. …”
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Parental Assessment of Infantile Hemangioma Cosmetic Clinical Outcomes: Results of the Spanish Hemangioma Nationwide Prospective Cohort by M. Colmenero-Sendra, J. del Boz-González, E. Baselga Torres, J. Bernabéu-Wittel, E. Roé-Crespo, A. Vicente, M. Valdivieso-Ramos, A. Martín-Santiago, S.I. Palencia-Pérez, M.T. Montserrat-García, A. Azón-Masoliver, M. Dañino, C. Tubau Prims, C. Prat, A. Giacaman, J.J. Domínguez-Cruz, A. Bauzá Alonso, M. Grau-Pérez, M.Á. Descalzo, I. García-Doval

“…Background: Functional impairment is the main consideration when it comes to choosing therapy for infantile hemangiomas (IH). …”
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[Artículo traducido] Evaluación parental de los resultados estéticos de los hemangiomas infantiles: resultados de la cohorte prospectiva española de hemangiomas infantiles by M. Colmenero-Sendra, J. del Boz-González, E. Baselga Torres, J. Bernabéu-Wittel, E. Roé-Crespo, A. Vicente, M. Valdivieso-Ramos, A. Martín-Santiago, S.I. Palencia-Pérez, M.T. Montserrat-García, A. Azón-Masoliver, M. Dañino, C. Tubau Prims, C. Prat, A. Giacaman, J.J. Domínguez-Cruz, A. Bauzá Alonso, M. Grau-Pérez, M.Á. Descalzo, I. García-Doval

“…Abstract: Background: Functional impairment is the main consideration when it comes to choosing therapy for infantile hemangiomas (IH). …”
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Uncovering the role of Gpr45 in obesity regulation by Eva O. Karolczak, Chia Li, Ivan C. Alcantara, Isabel M. Cohen, Claire Gao, Cuiying Xiao, Abigail I. Goldschmidt, Cynthia A. Pinkus, Junjie Li, Monica M. Li, Ryan M. Esquejo, Jean-Philippe Fortin, Kendra K. Bence, Marc L. Reitman, Michael J. Krashes

“…Methods: Three novel transgenic mouse models were engineered to investigate the functional contribution of Gpr45 to body weight and appetite regulation: 1) a global Gpr45 knockout, 2) a conditional floxed Gpr45 allele, and 3) a Gpr45-CreERT2 knock-in. …”
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Home Respiratory Therapies in Patients With Obstructive Sleep Apnea: A Value-based Care Model in Spain by Irene Cano-Pumarega, Candela Caballero-Eraso, Valentín Cabriada, Mar Mosteiro, Juan Fernando Masa, Ferran Barbé

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Path to Heritagization in Landscape Architecture: A Review of the Regeneration Design of Beijing Changchunyuan Park by Yufan ZHU

“…At the same time, efforts are made to focus on two types of design research that emphasize depth: One is the continuous refinement and deepening of the understanding of the essence of traditional garden culture, and the second is the potential of traditional gardens to respond to the changes in contemporary living environments. 3) Functional layout reconstruction: Through the rational deduction of site – city relationship, the park’s overall pattern of “north forest – central lake – south field” is constructed. …”
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Impacts of Chelated Iron Supplement with Organic Acid and Amino Acid on Growth Performance, Nutrient Digestibility, Feeding Behaviors, and Blood Parameters in Suckling Calves by Mahdi Ghavidel, Abdolhakim Toghdory, Taghi Ghoorchi, Mohammad Asadi

“…In the early stages of life, calves do not have a functional rumen, and it seems that they are more like monogastric animals that must obtain the nutrients they need. …”
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Biomarkers of cellular senescence predict risk of mild cognitive impairment: Results from the lifestyle interventions for elders (LIFE) study by Michelle M. Mielke, Roger A. Fielding, Elizabeth J. Atkinson, Zaira Aversa, Marissa J. Schafer, Steven R. Cummings, Marco Pahor, Christiaan Leeuwenburgh, Nathan K. LeBrasseur

“…Most studies of the SASP have focused on frailty and other functional outcomes. Senescent cells have been detected in the brains of patients with Alzheimer’s disease, but few studies have examined associations between plasma SASP markers and cognition. …”
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Supply-Demand Matching Evaluation and Coupling Coordination of Cultural Ecosystem Services in Urban Park Green Spaces by Yang YU, Xian YANG, Xiang LI, Liyuan QIAN, Sixiang ZHOU

“…The spatial differentiation of supply-demand coordination relationships is evident within the main urban area.ConclusionBy overlaying the results of supply-demand matching types with coupling coordination levels, the research categorizes the service ranges of all park green spaces into three functional zones: efficient zones, transitional zones, potential zones, and proposes optimization strategies accordingly. …”
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PDGFRα promoter polymorphisms and expression patterns influence risk of development of imatinib-induced thrombocytopenia in chronic myeloid leukemia: A study from India by Sameer Ahmad Guru, Rashid Mir, Musadiq Bhat, Imtiyaz Najar, Mariyam Zuberi, Mamta Sumi, Mirza Masroor, Naresh Gupta, Alpana Saxena

“…We hypothesized that two known functional polymorphisms, +68GA insertion/deletion and −909C/A, in the promoter region of the platelet-derived growth factor receptor-α gene may affect the susceptibility of chronic myeloid leukemia patients receiving imatinib treatment to the development of thrombocytopenia. …”
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Design and Implementation of Active Antennas for IoT-Based Healthcare Monitoring System by Umar Musa, Shaharil Mohd Shah, Huda A. Majid, Ismail Ahmad Mahadi, Mohamad Kamal A. Rahim, Muhammad Sani Yahya, Zuhairiah Zainal Abidin

“…Therefore, it is shown that the proposed dual-band active antennas in this work can be effectively integrated into the IoT-based healthcare monitoring system.…”
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Cambios en los síntomas de inatención, hiperactividad e impulsividad en niños y adolescentes con TDAH mediante los Deportes. Una revisión (Changes in the symptoms of inattention,... by Thamara Palma Marifil, Daniel Carroza Sepulveda, Romina Torres Lorca, Carlos Poblete-Aro, Cynthia Cadagan, Antonio Castillo-Paredes

“…Abstract: Introduction: Attention Deficit Disorder with Hyperactivity is a disorder associated with inattention, hyperactivity and impulsivity and can persist into adulthood, affecting social, academic and functional deterioration. Physical exercise has proven to be favorable for generating positive changes in the person suffering from any disease, thus improving their quality of life. …”
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The Mission of the Neocatechumenal Way in Times of Covid-19 by Bogumił Gacka

“…The argument  ̶  the secularization hypothesis  ̶  is that as education spreads, as incomes rise, and as the state takes over many functions of the church, people turn away from religion. …”
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Impact of shift work and obesity on risk of hyperuricemia in coal miners: A cross-sectional design based dose-response relationships and interaction analysis by Zeyuan ZHANG, Yingjun CHEN, Yingtong CHEN, Mengtian XIONG, Zichao PANG, Gaisheng LIU, Hongxia ZHAO, Liuquan JIANG, Qingsong CHEN

“…Restricted cubic spline functions were used to analyze the dose-response relationship between years of shift work, daily shift work hours, and HUA. …”
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Handwritten Words Image Character Extraction Adaptive Algorithm Based on the Multi-branch Structure by GUO Xiaojing, ZHAO Xiaoyuan, ZOU Songlin

“…The improved model comprises four functional components. The innovation of this study lies in several aspects. …”
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Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence by Viswanath Kumar Ganesan, S. Vinodh, Malolan Sundararaman, M. Vimala Rani, M. Mathirajan

“…These involve utilizing information technology and analytics more effectively, innovating manufacturing and service support systems, and employing novel problem-solving methods. …”
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