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  1. 73281
  2. 73282
  3. 73283

    Regulatory role of lnc-MAP3K13-3:1 on miR-6894-3p and SHROOM2 in modulating cellular dynamics in hepatocellular carcinoma by Kuai Chen, Manqin Zhu, Qinghua Hu, Hui Huang, Ka Chen, Xia Shuai, Jinshi Huang, Qiang Tao, Zhibin Guo

    Published 2025-01-01
    “…The miR-6894-3p mimic modulated the effects of lnc-MAP3K13-3:1 on cell proliferation, apoptosis, and migration. …”
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  4. 73284

    ATG16L1 restrains macrophage NLRP3 activation and alveolar epithelial cell injury during septic lung injury by Yan Bai, Xinyu Zhan, Qing Zhu, Xingyue Ji, Yingying Lu, Yiyun Gao, Fei Li, Zhu Guan, Haoming Zhou, Zhuqing Rao

    Published 2025-04-01
    “…Macrophages are essential for maintaining normal lung physiological functions and are implicated in various pulmonary diseases. …”
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  5. 73285

    Integrated proteomics and transcriptomics analysis reveals key regulatory genes between ER-positive/PR-positive and ER-positive/PR-negative breast cancer by Zhengjia Lu, Jiao Yang, Yang Feng, Jia Ming

    Published 2025-07-01
    “…Additionally, there were differences in functional pathway enrichment analysis (galactose_metabolism, glycolysis_gluconeogenesis, jak_stat_signaling_pathway, pentose_phosphate_pathway, et al.) and immune cell infiltration (CD8 T cell, Macrophages M1, et al.) between the high-risk and low-risk groups. …”
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  6. 73286

    Combined microbiome and metabolomics analysis of yupingfeng san fermented by Bacillus coagulans: insights into probiotic and herbal interactions by Yu Kang, Yanting Sun, Jinzhong Cui, Yuzhen Song, Zilong Sun, Huan Li, Ruiyan Niu, Hongxing Qiao

    Published 2025-04-01
    “…The study not only helps to elucidate the assembly mechanism and functional expression of microorganisms after Chinese traditional medicine fermentation, but also provides a solid scientific basis for the development of efficient and safe micro-ecological feed additives.…”
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    Article
  7. 73287

    Evaluation on Carbon Sequestration Capacity of 30 Common Landscaping Tree Species in Beijing by Jing QIAN, Sidong SHEN, Shuxin FAN, Li DONG

    Published 2025-01-01
    “…Beijing is facing various environmental problems, such as severe urban island heat effect caused by vast greenhouse gas emission, and air pollution. …”
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  8. 73288

    Key technologies of efficient extraction of coalbed methane (gas) in Guizhou coal mine area by Wang YI, Longjun LIANG, Lichong YAN, Zhihua YAN, Jie CHEN, Wei GAO, Yi LOU, Fuqin YANG, Haiyang HU, Jiawei ZHU

    Published 2025-03-01
    “…It innovated and explored the following high efficiency extraction technology of “four zones” linked Wells in coal mining areas with Guizhou characteristics: ① By laying multi-functional pumping vertical Wells or small inclination oriented Wells in the goaf, it was the first time in Guizhou to realize efficient extraction and development of pressure relief gas in the overlying coal-covered strata and coal-bed methane in the sweet coal seam below the goaf; ② Taking advantage of the characteristics of spatial and temporal dislocation in the production area, the multi-mode extraction mode of “coalbed methane well + relief well + underground drilling” is adopted for the first coal seam mined in the upper protective layer, which realizes the purpose of the upper and lower vertical combined extraction of coalbed methane (gas) Wells and effectively solves the problem of multi-source gas flooding into coal mining roadway and gas accumulation in the upper corner during coal mining under the condition of coal seam group development in Guizhou; ③ In the preparation area and planning area, combined with the terrain and geological characteristics of the two areas, the horizontal well “well factory” + “two pairs of right and wrong” overlapping well layout mode is adopted to realize the efficient extraction of coal bed methane in the plane in advance and pre-pumping of the sweet coal seam and the pressure relief gas in the overlying coal-laden rock in the subsequent mining process, and at the same time to achieve the goal of “replacing the roadway with Wells”; ④ In view of the development of multi-thin coal seam groups in the study area and the development characteristics of “three zones” in the overlying strata after mining, due to the continuous change of the role of “four zones”, the surface coalbed methane Wells are initially deployed in the production area or preparation area, and the “bridge plug bottom sealing + layer selection perforation” technology is adopted to innovate the “transformation” technology of well structure to achieve the purpose of “multi-purpose in one well”; It also provides new technical ideas and accumulated valuable engineering experience for gas management in coal mine area under the condition of multi-thin coal seam group development in Guizhou.…”
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  9. 73289

    Neutrophil: Lymphocyte Ratio and Platelet: Lymphocyte Ratio related to Disease Activity among Rheumatoid Arthritis in Erbil governorate/Iraq by Zekra Ali Aziz, Dashty A. Al-Bustany

    Published 2023-09-01
    “…RA if not treated early and properly it could lead to short life expectancy, decrease quality of life, functional disability, morbidity, and increase mortality, which ends with the societal burden (Mohamad et al.,2021; Kugyelka et al.,2016). …”
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  10. 73290

    Energy evolution and dynamic response characteristics of damaged sand-stone caused by pre-compression under impact loads by ZHENG Qiangqiang, LI Pingfeng, XU Ying, YIN Zhiqiang, HU Hao

    Published 2025-01-01
    “…With the increase of impact air pressure or the damage degree of sandstone, the dynamic strength reduction rate and the growth rate of energy dissipation density of the damaged sandstone under impact loading (impact compression and impact split tension) are both Weibull cumulative distribution functions related to the ratio of static load upper limit to static strength. …”
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  11. 73291

    Early Childhood Nutrition and Development in Atopic Families from Northeastern Bulgaria by Albena Toneva, Antoniya Hachmeriyan, Rouzha Pancheva, Miglena Marinova-Achkar

    Published 2025-03-01
    “…Conclusions: Our study reinforces the link between early feeding practices, neuropsychological development, and allergic conditions, emphasizing the lasting effects they have on children’s neurological health. …”
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  12. 73292

    Dynamic Surrogate Optimization of Vertically Stacked Nanosheet FET Based on Gaussian Process Regression by Christofer N. Yalung, Doldet Tantraviwat

    Published 2025-01-01
    “…In addition to applying normalization to make the weight assignment to the goal functions easier, a penalty component was incorporated to manage the <inline-formula> <tex-math notation="LaTeX">$V_{T}$ </tex-math></inline-formula>. …”
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  13. 73293

    The Emergence of AI-Driven Virtual Hospitals: Redefining Patient Care Beyond Physical Boundaries by Ifrah Hameed, Hafiz Muhammad Haseeb Khaliq

    Published 2025-04-01
    “…This modified analysis type assists healthcare professionals in making timely and accurate diagnoses for the development of fruitful treatment plans 2. This functionality not only increases the clinical intervention accuracy but also shortens the timeline necessary for the identification and treatment of health issues. …”
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  14. 73294

    Immune Profile of COVID-19 Survivors and Contacts During 9 Months: A Cohort Study by Valentina V. Tatarnikova, Natalya O. Kiseleva, Valentina I. Dubrovina, Vladimir A. Vishnyakov, Darya D. Bryukhova, Anna B. Pyatidesyatnikova, Konstantin M. Korytov, Munko B. Sharakshanov, Sergey V. Balakhonov, Haijuan Wang

    Published 2023-10-01
    “…Little is known about the possible long-term effects of COVID-19 on circulating leukocyte kinetics and functional T-cell activity after recovery. …”
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  15. 73295

    Development and Application of a Multi-scale Framework for Evaluating Floodplain Restoration Suitability Based on HEC-RAS by Shuoxing LI, Nanxi WANG, Yan ZHA

    Published 2025-06-01
    “…The case study in the Liuxi River Basin demonstrates that the restored floodplains can significantly enhance flood defense capabilities and ecological functions, while also supporting recreational and socio-economic needs at multiple spatial scales. …”
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  16. 73296

    Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study by Yang Yang, Junping Yin, Jian Li, Bo Liu, Ming Li, Qiao Huang, Xianglin Yuan, Christian Kurts, Guangyuan Hu, Qi Mei, Xi Tang, Alexander Böhner, Amy Bryant

    Published 2022-03-01
    “…Anti-COVID-19 vaccination may have functional implications for immune checkpoint inhibitor treatment in patients with cancer. …”
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  17. 73297

    The PKS–NRPS Gene <i>BBA_09856</i> Deletion Mutant of <i>Beauveria bassiana</i> Enhanced Its Virulence Against <i>Ostrinia furnacalis</i> Larvae and Strengthened the Host Plant’s R... by Yanan Wang, Xiaowei Zou, Xiaomin Zhu, Ji Qi, Jianfeng Liu, Zhengkun Zhang

    Published 2025-03-01
    “…However, they are among the few biosynthetic gene clusters with unknown functions in <i>B. bassiana</i>. To investigate the role of the hybrid PKS–NRPS synthetase gene <i>BBA_09856</i> in <i>B. bassiana</i>, we constructed a mutant strain, ∆<i>BBA09856</i>-WT, by deleting the <i>BBA_09856</i> gene through Agrobacterium-mediated transformation. …”
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  18. 73298

    Application of color Doppler ultrasound in uremia patients with auto angiostomy by Wei Jing-tuan, Chen Su-e, Shao Xiu-hua, Xu Qian-lei, Cen Jie

    Published 2025-06-01
    “…ObjectiveTo analyze influencing factors for the maturation of autogenous radial arterio-cephalic venous fistulas (AVF) in uremia patients by color Doppler ultrasound (CDU), and to create a CDU-based system to assess the maturation of AVF.MethodsA total of 91 uremia patients treated in the Functional Department of Shanghai Minhang District Hospital of Integrated Traditional Chinese and Western Medicine from June 15, 2023 to August 15, 2024 were selected as the research subjects. …”
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  19. 73299

    Catalase Activity in the Brain Is Associated with Recovery from Brain Injury in a Piglet Model of Traumatic Brain Injury by Stephanie T. Dubrof, Sarah L. Schantz, Taylor H. LePage, Sydney E. Sneed, Savannah R. Cheek, Holly A. Kinder, Kylee J. Duberstein, David A. DeWahl, Jerry O. Stern, Alexander B. Baguisi, Erin E. Kaiser, Franklin D. West, Hea Jin Park

    Published 2025-06-01
    “…Oxidative stress significantly exacerbates primary TBI, leading to increased levels of intracerebral cell death, tissue loss, and long-term functional deficits in surviving patients. Catalase and superoxide dismutase (SOD) mitigate oxidative stress and play a critical role in dampening injury severity. …”
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  20. 73300

    Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

    Published 2022-09-01
    “…This is a concern because it is unclear whether contingency measures can meet their goal of achieving functionally equivalent patient outcomes when resource allocation must be balanced with patient-centered care.[18] The care under contingency standards is meant to be functionally equivalent to regular care. …”
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