Plasma microRNA signatures of aging and their links to health outcomes and mortality: findings from a population-based cohort study by Lieke M. Kuiper, Michelle M. J. Mens, Julia W. Wu, Jaap Goudsmit, Yuan Ma, Liming Liang, Albert Hofman, Trudy Voortman, M. Arfan Ikram, Jeroen G. J. van Rooij, Joyce B. J. van Meurs, Mohsen Ghanbari

“…Overall, larger effect estimates were observed for mirPA, mirFI, and mirMort compared to mirAge. …”
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Quality of life and its determinants in women with delayed conception in low-mid socioeconomic neighbourhoods of Northern India: a cross-sectional study by James Kiarie, Sarmila Mazumder, Rita Kabra, Gitau Mburu, Ndema Habib, Ranadip Chowdhury, Neeta Dhabhai, Barsha Gadapani Pathak

“…Background The inability to conceive or delay in conception has negative and multidimensional effects on health and well-being, daily functioning and societal interactions. …”
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Isolation of a novel manganese-oxidizing bacterium Lysinibacillus xylanilyticus M125: characterization, structural evolution, and Cd-adsorption activity of biogenic Mn oxides produ... by Xiaoju Li, Xinyi Yuan, Yuxia Wei, Lianqi He, Yuanyuan Li, Meiquan Qiu, Yang Liu, Nannan Dong, Chengjia Zhang, Xin Pang, Xin Pang, Xin Pang

“…The Mn-oxidation ability of this strain was determined by the LBB method. The effects of different pH, temperature, and Mn2+ concentrations on bacterial growth and Mn2+ oxidation were evaluated by OD600nm and LBB method. …”
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Digital twins suggest a mechanistic basis for differing responses to increased flow rates during high-flow nasal cannula therapy by Hossein Shamohammadi, Sina Saffaran, Roberto Tonelli, Valentina Chiavieri, Giacomo Grasselli, Enrico Clini, Tommaso Mauri, Declan G. Bates

“…Higher flow rate dependent positive end-expiratory pressure in digital twins of non-responders did not cause recruitment, and reduced tidal volumes due to higher functional residual capacities—to compensate for the resulting worsened gas-exchange, non-responders increased their respiratory effort, in turn increasing patient self-inflicted lung injury (P-SILI) indicators. …”
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Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: A single-blind, rand... by Jennifer Wenborn, Aidan G O'Keeffe, Gail Mountain, Esme Moniz-Cook, Michael King, Rumana Z Omar, Jacqueline Mundy, Jane Burgess, Fiona Poland, Stephen Morris, Elena Pizzo, Myrra Vernooij-Dassen, David Challis, Susan Michie, Ian Russell, Catherine Sackley, Maud Graff, Tom Swinson, Nadia Crellin, Sinéad Hynes, Jacki Stansfeld, Martin Orrell

“…<h4>Background</h4>We aimed to estimate the clinical effectiveness of Community Occupational Therapy for people with dementia and family carers-UK version (Community Occupational Therapy in Dementia-UK version [COTiD-UK]) relative to treatment as usual (TAU). …”
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Differential Expression Characteristics of Two Isoforms <i>nr5a2f</i> and <i>nr5a2m</i> in Gonadal Differentiation of Chinese Giant Salamanders, <i>Andrias davidianus</i> by Dan Hu, Guanglve Li, Guohua Zou, Jiaqing Xu, Wenyin Luo, Qiaomu Hu

“…These results suggested that <i>Nr5a2</i>f and <i>Nr5a2m</i> exhibited different expression patterns in the process of sex differentiation, which provided a foundation for further functional characterizations.…”
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Impact of multi-strain probiotics supplementation on growth, immune responses and physiological traits in backyard poultry of Andaman and Nicobar Islands, India by Neha Halder, Neha Halder, Siddhartha Narayan Joardar, Jai Sunder, Arun Kumar De, Debasis Bhattacharya, Ahmed Abd El Wahed, Rea Maja Kobialka, Madathiparambil Gopalakrishnan Madanan, Samiran Mondal

“…In short, multi-strain probiotics supplementation showed its potential as an overall growth promoter in terms of improved growth performance, favorable physiological functions, enhanced immunomodulatory effects and better intestinal morphology in a widely reared backyard poultry breed of Andaman and Nicobar Islands, India, hence can be nominated as a potential alternative to commercial antibiotics at ground level.…”
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Lessons from implementation research on community management of Possible Serious Bacterial Infection (PSBI) in young infants (0-59 days), when the referral is not feasible in Palwa... by Rupak Mukhopadhyay, Narendra Kumar Arora, Pradeep Kumar Sharma, Suresh Dalpath, Priya Limbu, Geetanjali Kataria, Rakesh Kumar Singh, Ramesh Poluru, Yogesh Malik, Ajay Khera, P K Prabhakar, Saket Kumar, Rakesh Gupta, Harish Chellani, Kailash Chander Aggarwal, Ratan Gupta, Sugandha Arya, Samira Aboubaker, Rajiv Bahl, Yasir Bin Nisar, Shamim Ahmad Qazi

“…PHCs and CHCs became functional and managed 150 (40%) sick young infants with PSBI. …”
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Dynamic association of serum albumin changes with inflammation, nutritional status and clinical outcomes: a secondary analysis of a large prospective observational cohort study by Yonghao Li, Liru Chen, Xin Yang, Hongyuan Cui, Zijian Li, Wei Chen, Hanping Shi, Mingwei Zhu

“…Significant ALB decline was also strongly associated with worsened nutritional status, weight loss at discharge, exacerbated gastrointestinal symptoms, functional impairments, and edema (P < 0.001 for all). …”
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Multiple Hub Genes as Diagnostic and Therapeutic Targets Inducing Inflammation and Angiogenesis in Retinopathy of Prematurity by Du C, Tian Y, Liu Y, Shi Y, Chen X, Chai H, Zhang Y, Shen H, Zhang L

“…WGCNA was utilized to obtain oxygen-induced retinopathy (OIR)-related modules, and then key genes were obtained in the intersection of DEGs and the above modules. Biological functions and pathways of key genes were enriched through DAVID, Metascape and Gene set enrichment analysis. …”
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Comorbid anxiety, loneliness, and chronic pain as predictors of intervention outcomes for subclinical depressive symptoms in older adults: evidence from a large community-based stu... by Stephanie Ming Yin Wong, Dara Kiu Yi Leung, Tianyin Liu, Zuna Loong Yee Ng, Gloria Hoi Yan Wong, Wai Chi Chan, Terry Yat Sing Lum

“…Despite their overall effectiveness, a small but notable subgroup tends to be less responsive to interventions. …”
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Penerapan Metode K-Means Clustering dan Simple Moving Average untuk Memprediksi Jenis Penyakit di Provinsi Jawa Timur by Shynta Ayu Dwi Darmawan, Karmilasari

“…Disease case trend prediction was successfully implemented using historical data over a 5-year period, providing significant insights for health planning. Functional and browser compatibility tests showed that the system runs as expected in various environments. …”
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Use of a multidimensional RAPID3 questionnaire to assess the achievement of remission and minimal disease activity in patients with early psoriatic arthritis treated according to T... by E. Yu. Loginova, T. V. Korotaeva, A. D. Koltakova

“…DAS and DAS28, HAQ and RAPID3 functional index were estimated. The number of patients achieving LDA, DAS/DAS28 remission, and MDA were determined. …”
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Optimization of the Screw Conveyor Device Based on a GA-BP Neural Network by Qiang Guo, Yunpeng Zhuang, Houzhuo Xu, Wei Li, Haitao Li, Zhidong Wu

“…It was proven that GA—BP could effectively compensate for the deficiencies of the BP neural network and substantially enhance the model’s accuracy. …”
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Three different methods for ZnO-RGO nanocomposite synthesis and its adsorption capacity for methylene blue dye removal in a comparative study by Safaa A. Hussein, Gharib M. Taha, F. A. Adam, Marwa A. Moghazy

“…FTIR analysis approves that combining ZnO with RGO affects the functional groups of the three nanocomposite surfaces. …”
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Characterizing Patient-Reported Fatigue Using Electronic Diaries in Neurodegenerative and Immune-Mediated Inflammatory Diseases: Observational Study by Adrien Bennetot, Rana Zia Ur Rehman, Robbin Romijnders, Zhi Li, Victoria Macrae, Kristen Davies, Wan-Fai Ng, Walter Maetzler, Jennifer Kudelka, Hanna Hildesheim, Kirsten Emmert, Emma Paulides, C Janneke van der Woude, Ralf Reilmann, Svenja Aufenberg, Meenakshi Chatterjee, Nikolay V Manyakov, Clémence Pinaud, Stefan Avey

“…ObjectiveThis study aimed to evaluate the feasibility and acceptability of using a high-frequency eDiary to capture intraday variability in fatigue and to compare eDiary data with scores obtained from the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F), a validated weekly recall PRO. …”
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Barriers to and facilitators of clinician acceptance and use of artificial intelligence in healthcare settings: a scoping review by Alex Federman, Yufei Wang, Jalayne J Arias, Catherine E A Scipion, Margaret A Manchester

“…Overall, drivers of clinician AI acceptance and use were ambivalent, functioning as either barriers or facilitators depending on context. …”
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Heterogeneous characteristics of γδ T cells in peripheral blood of diffuse large B-cell lymphoma by Peng-Lin Wang, Wen-pu Lai, Jia-Mian Zheng, Xiao-Fang Wu, Jian-Nan Zhan, Ting-Zhuang Yi, Zhen-Yi Jin, Xiu-Li Wu

“…Our results revealed that while γδ T cells possess anti-tumor capacities, their functional effectiveness is diminished due to differentiation into exhausted subpopulations. …”
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A novel ecological risk assessment method of potentially toxic elements based on soil nematode communities by Xiujuan Yang, Li Cao, Bijun Cheng, Huirong Duan, Zixuan Fu, Xiaofang Xu, Qianying Xiang, Shuhan Wang, Xiaoqing Yan, Zhihong Zhang, Hongmei Zhang

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Le fromage en Gaule à l’âge du Fer et à l’époque romaine : état des lieux pour sa production et analyse de sa place dans le monde antique by Alain Ferdière, Jean-Marc Séguier

“…However, the search for this documentation required a strict functional and morphological definition of the concept of cheese strainer. …”
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