Mitochondrial proteins and congenital birth defect risk: a mendelian randomization study by Xin-yu Li, Da-tao Li, Yi-yuan Li, Zhi-cheng Xu, Qun Zhang, Xia Chen, Feng Xu, Ru-hong Zhang

“…Further large-scale and functional investigations are warranted to corroborate these genetic inference results and elucidate underlying mechanisms that may inform translational applications.…”
Get full text

Abstract 203: Predicting Outcomes After Mechanical Thrombectomy: Early vs Delayed Neurological Improvement in the SELECT Database by K. Rose Duncan, Deep Pujara, Amrou Sarraj

“…Delayed neurological improvement may be the result of microvasculature effects and inflammatory changes, and is likely multifactorial. …”
Get full text

Juvenile idiopathic arthritis: clinical case by I. V. Zorin, A. L. Frolenko, G. K. Karymova, D. S. Mesyats, Z. T. Alsheeva

“…In the etiology of JIA, a combination of various exogenous and endogenous damaging factors and hypersensitivity of the body to their effects plays a role. Pathogenetically, as a result of the presentation of a foreign antigen to T-lymphocytes, activation and proliferation of T-lymphocytes occur with the production of proinflammatory cytokines (IL-1, IL-6, IL-8, IL-17, tumor necrosis factor α, etc.). …”
Get full text

Occurrence of Alternaria Toxins, Ochratoxin A and Aflatoxins B1 in Green Arabic Coffee (Coffea arabica) in Saudi Arabia: Risk Assessment on HepG-2 Cell Line and Male Albino Rats by Ahmed Hashim Almusallam, Ahmed Mahmoud Ismail

“…Our results indicated the synergistic effect of the combined different mycotoxins against HepG-2 human liver cancer cells and male albino rats. …”
Get full text

Tae-miR396b regulates TaGRFs in spikes of three wheat spike mutants by Ziping Yao, Qi Wang, Ying Xue, Zhiheng Liang, Yongjing Ni, Yumei Jiang, Peipei Zhang, Ting Wang, Qiaoyun Li, Lei Li, Jishan Niu

“…Tae-miR396b had different regulatory effects on TaGRFs between Guomai 301 and its mutants. …”
Get full text

Nuclear factor erythroid 2-related factor 1 regulates the expression of proteasomal genes in ketotic cows and protects mammary cells against free fatty acid–induced endoplasmic ret... by Taiyu Shen, Shijie Xia, Muhammad Usman, Xinyi Xu, Juan J. Loor, Chuang Xu

“…This suggested a marked negative effect of high FFA on NFE2L1 and proteasomal homeostasis. …”
Get full text

CALL FOR PAPERSFOR THE SPECIAL ISSUE OF Zeszyty Teoretyczne Rachunkowości (ZTR – The Theoretical Journal of Accounting) in 2026

“…The following thematic areas are of particular interest in the light of the presented challenges:•Redesigning financial and managerial accounting systems to better assess how effectively tasks are carried out and how value is derived from these tasks •Developing sustainability-oriented managerial dashboards•Integrating AI and big data into financial and managerial reporting practices•The ethical responsibilities of financial and managerial accountants in the digital age•Managerial accounting education: redefining curricula for new roles•Case studies of organizational transformation in management accounting departments•Cross-functional collaboration between accountants and sustainability officers•The challenges of measuring social and environmental impacts in cost systems•The implications of fluid organizational boundaries on internal control and reporting•Strategic performance measurement in disruptive times•The development of accounting innovation through advanced budgeting techniquesThe issues mentioned above are not exhaustive in terms of the scope and complexity of research into accounting expanded horizons. …”
Get full text

Financial Toxicity and Kidney Disease in Children and Adults: A Scoping Review by Siligato R, Gembillo G, De Giorgi A, Di Maria A, Scichilone LM, Capone M, Vinci FM, Nicoletti S, Bondanelli M, Malaventura C, Storari A, Santoro D, Dionisi S, Fabbian F

“…Health care professionals need to improve their knowledge about the relationship between FT and renal disease; there is a paucity of data regarding the effects of FT on different outcomes, although this nonmedical risk factor can negatively influence kidney health and quality of life. …”
Get full text

rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors by Miyoung Kim, Eun Ju Lee, Donghoon Choi, Sara Ferrando-Martinez, Minji Lee, Sun-Kyoung Im, Seungtae Baek, Mankyu Ji, Seung Taek Ji, Daeun Kim, Jun-Young Lee, Alexandra Wolfarth

“…Most importantly, rhIL-7-hyFc increases infiltration of a CD62L+Ly108+ early progenitor population of exhausted CD8+ T cells (TPEX), which may retain long-term proliferation capacity and replenish functional effector CD8+ T cells. hIL-2/TCB2c induces differentiation of CD62L+Ly108+ TPEX rapidly into CD101+ terminally differentiated subsets (terminally exhausted T cell (TEX term)). …”
Get full text

Efficacy evaluation of Kirschner wire tension band combined with anatomical locking plate in the treatment of Mayo type II olecranon fractures by Chaode Cen, Nan Yin, Yan Wu, Yuehua Xie, Daqing He, Yong Zhang, Jun Jiang, Ya Zhu, Jie Zhou, Yongfei Cao

“…Conclusion Both operative procedures effectively treat Mayo type II olecranon fractures. …”
Get full text

Comparison of clinical efficacy and radiological findings of interspinous dynamic stabilization system versus unilateral biportal endoscopy for lumbar spinal stenosis: a retrospect... by Dongyue Li, Yunzhong Cheng, Xuanyu Chen, Peng Yin, Qingjun Su

“…Intergroup comparisons of these functional outcomes revealed no significant differences across all timepoints (P > 0.05). …”
Get full text

Bladder cancer microbiome and its association with chemoresponse by Rashida Ginwala, Laura Bukavina, Laura Bukavina, Mohit Sindhani, Erika Nachman, Erika Nachman, Suraj Peri, Jodie Franklin, John Drevik, Sarah Christianson, Daniel M. Geynisman, Alexander Kutikov, Philip H. Abbosh, Philip H. Abbosh

“…Lastly, urine from bladder cancer patients harbored abundant Gammaproteobacteria, which in cell culture experiments, detoxified gemcitabine, a commonly used therapy in bladder cancer.ConclusionsIn summary, we identify many new relationships between the microbiome and bladder cancer that are clinically relevant and lay the groundwork important functional studies in the future.…”
Get full text

World Health Organization African Region national heads of units of diagnostics and laboratory services meetings proceedings by Sheick Oumar Coulibaly, Michelle Amri, Christine Vuguziga, Aminata Binetou-Wahebine Seydi, Lorna Maria Aine, Bertha Kembabazi, Sokona Sy, Lindiwe Elizabeth Makubalo

“…Diagnostic and laboratory services influence the efficiency and effectiveness of both clinical and public health functions, including diagnosis, treatment, health promotion, disease prevention, surveillance and response, and research. …”
Get full text

Assessment of Aerodynamic Properties of the Ventilated Cavity in Curtain Wall Systems Under Varying Climatic and Design Conditions by Nurlan Zhangabay, Aizhan Zhangabay, Kenzhebek Akmalaiuly, Akmaral Utelbayeva, Bolat Duissenbekov

“…However, based on the outcomes of the analytical model, it was concluded that the method does not adequately account for the effects of solar radiation and vertical temperature gradients on airflow within ventilated façades. …”
Get full text

Biosynthesis and activity of Zn-MnO nanocomposite in vitro with molecular docking studies against multidrug resistance bacteria and inflammatory activators by Samy Selim, Tarek M. Abdelghany, Mohammed S. Almuhayawi, Mohammed K. Nagshabandi, Muyassar K. Tarabulsi, Mohammed Yagoub Mohammed Elamir, Asmaa A. Alharbi, Soad K. Al Jaouni

“…Transmission electron microscopy confirmed irregular particles with a spherical-like shape ranging from 25.13 to 36.21 nm. Numerous functional groups were detected on the surface of Zn-MnO nanocomposite via Fourier-transform infrared spectroscopy. …”
Get full text

The Relationship Between Psychosocial Factors and Response to Epidural Steroid Injection for Chronic Lumbosacral Radicular Pain: A Prospective Pilot Study by Stensland M, Sanford E, Houle TT, McGeary C, Cobos BA, Lugosi S, Lehman L, Nabity PS, Covell C, Fitzgerald E, Mojallal M, Reed DE, Pangarkar S, Eapen BC, Nanda U, McCormick ZL, McGeary D

“…Future research with a larger sample should focus on deepening our understanding of the role of psychosocial functioning as a potential mechanism of treatment response in patients undergoing ESI procedures. …”
Get full text

Abstract 235: General Anesthesia vs. Non‐General Anesthesia in Endovascular Treatment for Patients with Acute Ischemic Stroke by Mohamed F. Doheim, Abdullah Sultany, Alhamza R. Al‐Bayati, Raul Nogueira

“…We then pooled data for the main procedural, safety, and efficacy outcomes with odds ratios (ORs) and 95% CI for dichotomous data and mean difference (MD) with 95% CI for continuous data under random effect model. Results Eight RCTs were included in the final analysis (n=1203) with seven of them reporting data for the anterior circulation (n=1116) and one for the posterior circulation (n=87). …”
Get full text

Cytokine Gene Variants as Predisposing Factors for the Development and Progression of Coronary Artery Disease: A Systematic Review by Fang Li, Yingshuo Zhang, Yichao Wang, Xiaoyan Cai, Xiongwei Fan

“…Single nucleotide polymorphisms (SNPs), capable of generating functional modifications in IL genes, appear to be associated with CAD risk. …”
Get full text

Evaluasi Sistem Informasi Menggunakan Technology Acceptance Model dengan Penambahan Variabel Eksternal by Ria Andriani, Arief Setyanto, Asro Nasiri

“…KRS (Study Plan Card) functions to manage courses that will be taken in the relevant semester by students, filling in KRS using the account given by the campus by entering using an identity in the form of a Student Identification Number and password, students can fill in the Card Study Plan from anywhere with information that has been provided on the website, so that it can be said that the Card Study Plan System is a bridge between students and managers in this case the academic section at the University of Amikom. …”
Get full text

Replenishing co‐downregulated miR‐100‐5p and miR‐125b‐5p in malignant germ cell tumors causes growth inhibition through cell cycle disruption by Marta Ferraresso, Shivani Bailey, Luz Alonso‐Crisostomo, Dawn Ward, Christos Panayi, Zachary G. L. Scurlock, Harpreet K. Saini, Stephen P. Smith, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Nicholas Coleman, Matthew J. Murray

“…Here, we investigated the causes and consequences of downregulated miR‐99a‐5p/miR‐100‐5p (functionally identical) and miR‐125b‐5p levels in malignant GCTs regardless of age, site, or subtype. …”
Get full text