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  1. 7301

    Functional characterization of all CDKN2A missense variants and comparison to in silico models of pathogenicity by Hirokazu Kimura, Kamel Lahouel, Cristian Tomasetti, Nicholas Jason Roberts

    Published 2025-04-01
    “…We found that 17.7% of all missense variants were functionally deleterious. We also used our functional classifications to assess the performance of in silico models that predict the effect of variants, including recently reported models based on machine learning. …”
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  2. 7302

    Acorn Flour as A Functional Ingredient: Impacts on Health and Baking Properties in Wheat - Based Products by Sikora Fryderyk, Ochmian Ireneusz, Sobolewska Magdalena

    Published 2024-12-01
    “…The conclusions underscore acorn flour's potential as a functional ingredient that not only enhances bread's nutritional profile but also contributes to food sustainability.…”
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  3. 7303

    Potential functional changes in native lysozyme induced by carbon nanotubes studied by molecular dynamics simulations by S. Mehdi Vaez Allaei, Mehriar Amininasab, Hrachya Ishkhanyan, Armen H. Poghosyan

    Published 2025-04-01
    “…Abstract A carbon nanotube (CNT) can affect biological systems, ranging from toxicity to changes in functionality. Here, a series of long-scale (1–2 µs) molecular dynamics simulations were conducted to investigate the adsorption and interaction of lysozyme with the CNT, a possible mechanism for altering protein flexibility and function. …”
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  4. 7304
  5. 7305
  6. 7306
  7. 7307

    Bioactive compounds from New Zealand's native edible plants: Their role in future functional foods by Ali Rashidinejad

    Published 2024-12-01
    “…Abstract This commentary discusses the significant role of bioactive compounds found in New Zealand's native edible plants in the development of functional foods. It begins by highlighting the diverse range of bioactive compounds (e.g., flavonoids, polyphenols, and alkaloids) present in these plants, which exhibit various health‐promoting properties such as anti‐inflammatory, antioxidant, and antimicrobial effects. …”
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  8. 7308

    Unravelling the temporal dynamics of community functions in protists induced by treated wastewater exposure using metatranscriptomics by Manan Shah, Guido Sieber, Aman Deep, Daniela Beisser, Jens Boenigk

    Published 2025-07-01
    “…While the ecological effects of TWW on microbial diversity have been studied, understanding the functional responses of protist communities remains limited. …”
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    Article
  9. 7309

    Cell Progression and Survival Functions of Enzymes Secreted in Extracellular Vesicles Associated with Breast and Prostate Cancers by Cosmos Ifeanyi Onyiba, Niwasini Krishna Kumar, Christopher J. Scarlett, Judith Weidenhofer

    Published 2025-03-01
    “…Findings in this review reveal that the EV enzyme cargo could exert cell progression functions via adhesion, proliferation, migration, invasion, and metastasis. …”
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  10. 7310

    Adiabatic state conversion for (a)cyclic non-Hermitian quantum Hamiltonians of generalized functional form by Nicholas S. Nye, Nikolaos V. Kantartzis

    Published 2024-12-01
    “…Analytical solutions in terms of Airy and modified Bessel functions have been retrieved for linear and hyperbolic temporal dependencies in parity-time-symmetric-like systems, which were subsequently studied in the slowly varying limit to show conversion to one of the instantaneous eigenstates. …”
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  11. 7311

    An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis. by Dorothee A Vogt, Raul Andino

    Published 2010-06-01
    “…This allows us to study the function of the element in promoting positive-strand RNA synthesis, independently of its function in negative-strand initiation. …”
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  12. 7312

    The impact of physical and mind exercise on functional disability in activities of daily living among the oldest old by Song Wang, Zhengyu Wu, Zhen Guo, Fei Wang, Bo Liu

    Published 2025-05-01
    “…This study investigates the effects of physical and mind exercise on functional impairment in activities of daily living among older adults aged 80 years and older. …”
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  13. 7313
  14. 7314

    Sociodemographic moderators of the association between functional limitations and depressive symptoms among Chinese older adults by Haijun Hao, Haijun Hao, Junyue Yue, Yeong Hun Yeo

    Published 2025-08-01
    “…IntroductionDepressive symptoms among older adults are a growing public health concern, particularly in rapidly aging populations like China. Functional limitations, commonly experienced with advancing age, have been shown to exacerbate depressive symptoms.MethodsThis study investigates the moderating effects of sociodemographic factors (including individual, familial, and society) on the association between functional limitations and depressive symptoms among Chinese older adults, using data from the 2018 Chinese Longitudinal Healthy Longevity Survey (CLHLS). …”
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  15. 7315

    Depth Function of Available Phosphorus and Potassium Distribution in Different Mid-Mesopotamian Plain Saline Soils by Kusay A. Wheib, Afrah K. Al-Jubouri, Husian A. Isa, Wejdan T. Kadhim

    Published 2025-06-01
    “…Saline soils in Alsweira greater area representing mid-Mesopotamian plain saline soils were selected to study the effect of salt accumulation on available potassium and phosphorus in soil as a depth function. …”
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  16. 7316

    Exploring the balance between functionality and aesthetics: an analytical framework and pragmatic consideration of the anthropomorphism of service robots by Xin Xin, Wenchao Liu

    Published 2025-04-01
    “…Following the systematic review methodology, our findings indicate that the design of service robots necessitates a careful equilibrium between functional capabilities and aesthetic considerations. …”
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  17. 7317

    Pulmonary Function Tests in Hypertensive Patients Attending Zewditu Memorial Hospital, Addis Ababa, Ethiopia by Mekuriaw Mesfin Birhan, Yekoye Abebe

    Published 2018-01-01
    “…However, studies that show the effect of hypertension on the lungs are limited. Objective. …”
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  18. 7318

    Bilateral functional connectivity of the basal ganglia in patients with Parkinson's disease and its modulation by dopaminergic treatment. by Simon Little, Huiling Tan, Anam Anzak, Alek Pogosyan, Andrea Kühn, Peter Brown

    Published 2013-01-01
    “…However, little is known about the functional connectivity of the two basal ganglia across hemispheres and specifically the role beta plays in this. …”
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  19. 7319

    Mobile application leads to psychological improvement and correlated neuroimmune function change in subjective cognitive decline by Merav Catalogna, Nira Saporta, Bar Nathansohn-Levi, Tal Tamir, Ariel Shahaf, Shira Molcho, Shai Erlich, Shahar Shelly, Amir Amedi

    Published 2025-06-01
    “…Assessments included psychological measures, immunological analysis, and for a subgroup of the participants also resting-state functional connectivity (rsFC). The intervention significantly reduced proinflammatory mediators (TNF-α, IL-17, IL-23, MCP-1, IFN-γ, and IL-12) and improved depression, anxiety, resilience and well-being with sustained effect over a three-week follow-up. …”
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  20. 7320

    Functionality Evaluation and Testing of Web-Based Sparepart Sales System Using Black-Box Method by Rizky Firman Syah, Agus Prasetyo Utomo

    Published 2025-07-01
    “…The evaluation focused on the system's feature completeness, functional effectiveness, and service quality. Test results showed that key features, such as Home, Customer Registration, Login, Spare Parts Search, Ordering, Payment, and Sales Reports, functioned according to specifications. …”
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