Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction by Jingjing Chen, Dan Zhang, Chengxiu Zhu, Lin Lin, Kejun Ye, Ying Hua, Mengjia Peng

“…SHapley Additive exPlanations interpretability analysis revealed SUV39H1 as the dominant risk contributor, while GLUL exhibited a protective effect. Regulatory network reconstruction identified 32 transcription factors, 24 RNA-binding proteins, and 62 miRNAs as putative upstream regulators of key genes. …”
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Design and Analysis of a Novel Ocean Current Two-Coupled Crossflow Turbine Energy Converter by Shueei-Muh Lin, Wei-Le Huang, Didi Widya Utama, Yang-Yih Chen

“…Finally, the effects of several parameters on the performance of the energy converter are investigated. …”
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DFT analysis of the [3 + 2] heterocyclization reaction of ((1,2,4-triazole(1,3,4-oxadiazole)-3(2)-yl)methyl)thiopyrimidines by Yu. V. Karpenko

“…The article examines the mechanisms of the heterocyclization reaction using density functional theory (DFT) methods. A quantum-chemical analysis of the starting compounds, transition states, and products was conducted, with energy barriers and key reaction stages identified. …”
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Comprehensive analysis of RFC4 as a potential biomarker for regulating the immune microenvironment and predicting immune therapy response in lung adenocarcinoma by Jianqing Zheng, Na Lin, Bifen Huang, Min Wu, Lihua Xiao, Bingwei Zeng

“…A high RFC4 expression level was associated with a lower TIDE score, indicating a stronger therapeutic response to immunotherapy. Functional prediction of RFC4 suggested that RFC4 mainly participated in DNA replication and repair, and reshaped the TIME.ConclusionsRFC4 proved to be a promising biomarker for tumorigenesis and could effectively predict immunotherapy response in LUAD. …”
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Mechanistic study of CTHRC1 in promoting Wilms’ tumor progression by regulating M2-type tumor-associated macrophages polarization by Yingquan Zhuo, Xiaoyun Feng, Wenqi Zhang, Jun Du, Xu Sun, Xi Luo, Wei Wang, Hua Jiang, Huajian Gu

“…In vitro and in vivo experiments were performed to investigate the biological functions of CTHRC1 in WT and its effects on M2-TAMs polarization. …”
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A multi-omics Mendelian randomization identifies putatively causal genes and DNA methylation sites for asthma by Jia Wang, MD, Jinxin Hu, MS, Dan Qin, MD, Dan Han, MD, Jiapeng Hu, MD

“…While current therapies offer some relief, they often fall short in effectively managing symptoms and preventing exacerbations for numerous patients. …”
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Exploring the influence of sex and age on the quality and flavor of Huai goat longissimus thoracis et lumborum through transcriptomic and metabolomic analyses by Haoyuan Han, Ziru Kuai, Zhiyun Yao, Xi Lei, Huibin Shi, Jun Li, Kun Liu, Huiru Yin, Yongqing Wang, Kai Quan

“…Abstract Background The aim of this study was to investigate the effects of age and sex on the composition of fatty acids, amino acids, and vitamins in the longissimus thoracis et lumborum (LTL) of Huai goats. …”
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How does soil carbon sequestration affect greenhouse gas emissions from a sheep farming system? Results of an life cycle assessment case study by Pasquale Arca, Enrico Vagnoni, Pierpaolo Duce, Antonello Franca

“…We observed that the extensification of production system determined contrasting environmental effects when using different FUs accounting for soil Cseq. …”
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Prevalencia de neuromitos en estudiantes de Pedagogía en Educación Física de Chile (Prevalence of neuromyths in students of Physical Education Pedagogy of Chile) by Fernando Maureira, Elizabeth Flores Ferro, Franklin Castillo Retamal, Manuel Cortés Cortés, Sebastián Peña Troncoso, Valentina Bahamonde Acevedo, Sonia Cárdenas Begazo, Natalia Escobar Ruiz, Benjamín Cortes Escaffi

“…Introduction: the lack of a common language between neuroscience and education has generated erroneous interpretations about the functioning of the nervous system, giving rise to neuromyths. …”
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Hyperbaric oxygen pretreatment on endothelial cell injury via heat shock factor 1 in decompression sickness by Caiyi Xu, Quan Zhou, Xiangyang Meng, Jiahe Zhou, Xuhua Yu, Juan Zheng, Hongjie Yi, Hongjie Yi, Guoyang Huang, Weigang Xu

“…AKT inhibition substantially suppressed HSF-1 activation, whereas ERK1/2 and P38 MAPK inhibition had no effect. ROS scavenging with Mito-Tempo reduced AKT phosphorylation and HSF-1 activation. …”
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Comparative Analysis of a New Device-Assisted Mini-Incision Versus Conventional Surgery for Carpal Tunnel Syndrome: A Retrospective Study of 109 Cases by Guo T, Li C, Tian D, Gao R, Yu K, Sun N, Yang J, Bai J

“…But the incidence of wound pain and pillar pain was lower in Group A (wound pain: 0%; pillar pain:0%) compared to Group B (wound pain: 5.5%; pillar pain:7.3%).Conclusion: The device-assisted mini-incision technique provided comparable functional results to the conventional approach, with reduced complications and smaller incisions, supporting its use as a viable alternative in appropriate cases.Keywords: carpal tunnel syndrome, carpal tunnel release, mini-incision approach, conventional approach…”
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Genetic variants of the DLK1, KISS1R, MKRN3 genes in girls with precocious puberty by E. A. Sazhenova, O. Yu. Vasilyeva, E. A. Fonova, M. B. Kankanam Pathiranage, A. Yu. Sambyalova, E. E. Khramova, L. V. Rychkova, S. A. Vasilyev, I. N. Lebedev

“…The pathogenicity of identified genetic variants and the functional significance of the protein synthesized by them were analyzed according to recommendations for interpretation of NGS analysis results using online algorithms for pathogenicity prediction (Variant Effect Predictor, Franklin, Varsome, and PolyPhen2). …”
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Efficiency of surgical treatment of neovascular glaucoma: a retrospective analysis by A. V. Zolotarev, E. V. Karlova, M. V. Radaikina, A. A. Kuz'mina, O. V. Ryzhkova

“…The timely treatment of the underlying disease with Anti-VEGF and LC of the retina allows the patient to maintain visual functions, and increases the effectiveness of NVG surgery.…”
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Explainable multi-modal radiomics for early prediction of liver metastasis in rectal cancer: a multicentric study by Yaru Feng, Jing Gong, Yanyan Wang, Yanfen Cui, Tong Tong

“…The SHAP method elucidated the model’s functionality by highlighting key feature contributions. …”
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Choosing the Best Digital Health Literacy Measure for Research: Mixed Methods Study by Charlotte Brun Thorup, Mika Uitto, Kerryn Butler-Henderson, Sarah Wamala-Andersson, Merja Hoffrén-Mikkola, Diana Schack Thoft, Lisa Korsbakke Emtekær Hæsum, Gabriela Irrazabal, Laura Pruneda González, Katja Valkama

“…They should identify beneficiaries of digital health services, measure the impact of dHL interventions, and objectively evaluate functional skills. These tools should be evidence-based, validate instruments, interpret dHL results, and capture diverse experiences to reveal health behaviour changes. …”
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CLOUD COMPUTING AND BIG DATA AS CONVERGENT TECHNOLOGIES FOR RETAIL PRICING STRATEGIES OF SMEs by George SUCIU, Gyorgy TODORAN, Adelina OCHIAN, Victor SUCIU, Janna CROPOTOVA

“…The paper explains why retailers can no longer thrive without a science-based pricing system, defines and illustrates the right science-based approach, and calls out the key features and functionalities of leading science-based price optimization systems. …”
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Neural network prediction model based on Levy flight and natural biomimetic technology for its application in cancer prediction. by Ruiyu Zhan

“…We performed comparative analyses against other methodologies across various functions and public datasets to assess their effectiveness. …”
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TWO CASES OF PRIMARY AMYLOIDOSIS PRESENTING WITH VERTEBRAL AMYLOIDOMA by Ebru Kavak Yavuz, Vehbi Demircan, Abdullah Karakus, Orhan Ayyildiz

“…Cardiac examination ECHO showed normal heart chambers, normal left ventricular functions, EF%60. ECG examination was normal. VCD chemotherapy was started in the patient's treatment. …”
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Relationship between CTF1 gene expression and prognosis and tumor immune microenvironment in glioma by Hongqing Cai, Shen Tian, Angsi Liu, Guanchao Xie, Hongsheng Zhang, Xiaogang Wu, Jinghai Wan, Sai Li

“…Abstract Objective This study aimed to evaluate CTF1 expression in glioma, its relationship to patient prognosis and the tumor immune microenvironment, and effects on glioma phenotypes to identify a new therapeutic target for treating glioma precisely. …”
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Implications of the <i>STAT5B</i> and <i>C1QBP</i> Genes of Grain Aphid <i>Sitobion avenae</i> in the Transmission of Barley Yellow Dwarf Virus by Chiping Liu, Manwen Zhang, Chen Luo, Zuqing Hu

“…These findings highlight the functions of the <i>STAT5B</i> and <i>C1QBP</i> genes and identify <i>C1QBP</i> as a potential target gene for further RNAi-based studies to control the transmission of BYDV-GAV.…”
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