CREDIBILIDADE NO COTIDIANO PROFISSIONAL by Rogério Christofoletti, Denise Becker

“…Based on a survey applied to journalists in June and July 2024 (n=446), recruited online and in person during a national professional event, we obtained responses on the functioning and importance of credibility with sources and audiences, and on determining factors for maintaining public trust in journalism. …”
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The Role of PLIN3 in Prognosis and Tumor-Associated Macrophage Infiltration: A Pan-Cancer Analysis by Yang S, Liu H, Zheng Y, Chu H, Lu Z, Yuan J, Xu S

“…In LUAD, clofibrate was identified as a potential inhibitor of PLIN3’s pro-oncogenic functions.Conclusion: PLIN3 may serve as a potential biomarker and oncogene, particularly in LUAD. …”
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Immunomodulatory activity of Pleurotus pulmonarius crude extract to human monocyte against Cryptococcus neoformans by Artittaya Arromsava, Siriporn Chuchawankul, Navaporn Worasilchai, Pornpimon Angkasekwinai, Kamolporn Amornsupak

“…Abstract Background Treatment of Cryptococcus neoformans infection is still challenging due to high side effects and acquired drug resistance. Eliminating fungal infection requires monocytes and macrophages, which are weakened by the non-protective type-2 immune response induced by the pathogen. …”
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Mental Health Apps Available in App Stores for Indian Users: Protocol for a Systematic Review by Seema Mehrotra, Ravikesh Tripathi, Pramita Sengupta, Abhishek Karishiddimath, Angelina Francis, Pratiksha Sharma, Paulomi Sudhir, Srikanth TK, Girish N Rao, Rajesh Sagar

“…Although there is mounting research on the effectiveness of mental health apps, the majority of these are not accessible to the public and most of those available have not been researched. …”
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CRISPR/Cas9 screening identifies SUV39H2 as a key regulator of oHSV-1 resistance in oral squamous cell carcinoma by Manman Qiu, Qicheng Zhang, Rui Li, Rongrong Wei, Jiawei Zhao, Juan Tan, Hongkai Zhang, Wentao Qiao

“…The inhibitor OTS186935 targeting SUV39H2 was administered to evaluate its effects on viral replication both in vitro and in vivo. …”
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Advanced analysis via statistical physics model to study the efficiency of catechol removal from wastewater using Brazil nut shell activated carbon by Salah Knani, Ismahene Ben Khemis, Wassim Zahrouni, Besma Graba, Ridha Selmi, Safwat A. Mahmoud, Abdulaziz Alenazi, Abdulmajeed Alshammari, Guilherme Luiz Dotto

“…These results were utilized to elucidate the role of surface functionalities through statistical physics calculations. …”
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Alternative splicing in ovarian cancer by Liwei Wei, Yisheng Li, Jiawang Chen, Yuanmei Wang, Jianmin Wu, Huanming Yang, Yi Zhang

“…These novel splicing variants warrant further functional characterization to unlock the underlying molecular mechanisms. …”
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Research progress and prospects on resource utilization of coal gangue for soil remediation in China by Chengyong LIU, Wenzhe GU, Feng CUI, Yun ZHANG, Yanbin YANG, Fengqi QIU, Chaofeng YUAN, Haixing CHENG, Ming LI

“…Key technologies for the polymorphic separation of valuable and harmful components in coal gangue have been distilled, and the engineering application models for coal gangue soil utilization and their impact mechanisms on soil ecological functions have been discussed. The results shows that, coal gangue can improve soil structure, enhance water and nutrient retention, support stable beneficial microbial communities, and provide ecological benefits such as increased soil carbon sequestration and reduced greenhouse gas emissions. …”
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Cognitive benefits of folic acid supplementation during pregnancy track with epigenetic changes at an imprint regulator by L. Hilman, M. Ondičová, A. Caffrey, M. Clements, C. Conway, M. Ward, K. Pentieva, R. E. Irwin, H. McNulty, C. P. Walsh

“…Methylation of ZFP57 was analysed by EPIC arrays, pyrosequencing and clonal analysis, and transcription assessed by PCR-based methods. Functional consequences of altered methylation were examined in cultured cells with mutations or by inhibition of the main DNA methyltransferases. …”
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[Artículo traducido] La contaminación, un factor relevante del exposoma en el envejecimiento cutáneo y el papel de la fotoprotección multibeneficio by J. Santamaria, Y. Gilaberte, L. Prudkin, J. Piquero-Casals

“…Abstract: Skin aging is a complex, continuous, multifactorial process resulting from cumulative morphological and functional changes in the skin over time.This happens because of 2 processes: intrinsic and extrinsic skin aging. …”
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Association between taurine transporter SLC6A6 and breast cancer development and prognosis: a Mendelian randomization analysis by Xinping Huang, Hailong Shu, Man Xu, Weixiao Ke, Wanting Chen, Wenbin Huang, Hai Wang, Yifan Zhu, Yongxia Yang

“…Molecular docking, functional analysis, and immune infiltration analysis were employed to explore the mechanism of SLC6A6. …”
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SLC3A2 as a key anoikis−related gene for prognosis and tumor microenvironment remodeling in melanoma by Xiaojin Liu, Jiaheng Xie, Yingying Xiao

“…The clinical relevance and functional role of SLC3A2 were further validated using the BEST database and in vitro experiments, including shRNA-mediated knockdown, colony formation, and Transwell migration assays. …”
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Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis by Lijiao Chen, Shiyuan Luo, Ting Liu, Zhewei Shuai, Yifan Song, Qianzi Yang, Ying Wang, Hongjun Huang, Yan Luo

“…The anti-GDF15 monoclonal antibody ponsegromab was injected intracerebroventricularly before modeling, and cognitive and memory functions of the septic mice were assessed using fear-conditioning and novel object recognition tests. …”
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Young Scientists’ Motivation for the Research Activity in Russian Regional Universities by R. A. Dolzhenko, V. A. Karpilianskii, R. A. Hady, A. S. Didenko

“…In-depth interviews were conducted with the most successful respondents (N = 20) to comprehensively assess the factors of their professional activity, since it is the leaders, who primarily determine the effectiveness of functioning system.Results and scientific novelty. …”
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Uncovering the mechanism of resveratrol in the treatment of asthma: a network pharmacology approach with molecular docking and experimental validation by Li Chunxiao, Hou Xin, Liu Bowen, Sun Bingqing, Zhou Mengqi, Zhang Shuwen, Zhang Jingyuan, Lin Jiangtao

“…GO enrichment analysis identified 2,595 significant terms, associated with 2,402 biological processes, followed by 153 molecular functions and 40 cellular components. KEGG enrichment analysis identified 107 relevant pathways, including “apoptosis,” “TNF signaling pathway,” and “MAPK signaling pathway.” …”
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Biocompatibility and osteointegrative characteristics of zirconium ceramic implants for diaphyseal defect filling by Elena A. Volokitina, Maksim V. Saushkin, Irina P. Antropova, Sergey M. Kutepov, Svetlana A. Brilliant

“…It was previously proven that alloyed ceramic materials are attractive for tissue regeneration due to their functional properties, biological activity, and therapeutic effects provided by the introduced ions. …”

Association between atherogenicity indices and prediabetes: a 5-year retrospective cohort study in a general Chinese physical examination population by Xianli Qiu, Yong Han, Changchun Cao, Yuheng Liao, Haofei Hu

“…To address the natural relationships between the atherogenicity indices and risk of prediabetes, we applied Cox proportional hazards regression with cubic spline functions and smooth curve fitting, using a recursive algorithm to calculate inflection points. …”
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HUMAn, a Real-Time Evolutive Patient Model for Major Incident Simulation: Development and Validation Study by Maxence Laurent, Arnaud Jaccard, Laurent Suppan, Elio Erriquez, Xavier Good, Eric Golay, Dominique Jaccard, Mélanie Suppan

“…During the development phase, iterations led to the development of a heart-lung-brain interaction model coupled to functional blocks representing the main anatomical body parts. …”
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Impact of Digital Health on Patient-Provider Relationships in Respiratory Secondary Care Based on Qualitative and Quantitative Evidence: Systematic Review by Michaela Senek, David Drummond, Hilary Pinnock, Kjeld Hansen, Anshu Ankolekar, Úna O'Connor, Apolline Gonsard, Oleksandr Mazulov, Katherina Bernadette Sreter, Christina Thornton, Pippa Powell

“…Four main themes emerged: trust (foundational to the relationship), adoption factors (including clinical context and implementation drivers), confidence in technology (based on functionality and the evidence base), and connection (encompassing communication and a caring presence). …”
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Social service organizations report improvements in social services-health care integration in survey during California’s medicaid initiative (“CalAIM”) by Abigail Arons, Priscilla Alban-Acuna, Melora Simon, John Whaley, Nicole Fossier, Amy Simon, Rohan Rastogi, Caroline Fichtenberg

“…Contracted SSOs perceived improvements in health care-social services integration at both the patient and organizational levels, suggesting CalAIM is functioning as intended in the perception of SSOs. We demonstrate a feasible method for ongoing monitoring of the SSO perspective that can inform near-term policy directions to ensure small SSOs with close community ties are fully included as partners in CalAIM.…”
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