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72681
p27<sup>Kip1</sup> and Tumors: Characterization of <i>CDKN1B</i> Variants Identified in MEN4 and Breast Cancer
Published 2025-01-01“…Here, we analyzed the effect of four <i>CDKN1B</i> missense and nonsense mutations found in patients affected by MEN4 or cancers, namely, c.349C>T, p.P117S; c.397C>A, p.P133T; c.487C>T, p.Q163*; and c.511G>T, p.E171*. …”
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72682
Comparative analysis of maxillary expansion techniques using orthodontic appliances
Published 2020-03-01“…The subject of the study of many authors were changes in the bone and dental system, as well as the duration of treatment results obtained due to the use of functional devices with different rates of action. The rate of expansion depends on the level of applied forces and the mode of activation of the device. …”
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72683
Technology features of decellularization of human liver fragments as tissue-specific fine-grained matrix for cell-engineering liver construction
Published 2018-01-01“…One of the problems when you create a bioengineered liver, as an alternative to transplantation of the donor liver in the treatment of end-stage liver failure, is the matrix, able to temporarily perform the functions of the natural extracellular matrix (ECM) and provide the necessary conditions to maintain the viability of the liver cells. …”
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72684
Phase 1 trial of durvalumab (anti–PD-L1) combined with lenalidomide in relapsed/refractory cutaneous T-cell lymphoma
Published 2025-05-01“…Abstract: Selective targeting of the functionally exhausted malignant T cells in cutaneous T-cell lymphoma (CTCL) and distinct cells within the tumor microenvironment (TME) via programmed cell death 1/programmed cell death ligand 1 blockade (durvalumab) may restore an antitumor immune response. …”
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72685
Exploring the Shared Genetic Characteristics of Peri-Implantitis and Osteoporosis: A Transcriptomic Analysis Perspective
Published 2025-10-01“…Drugs targeting common genes may offer the potential for 'one drug, two effects'.…”
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72686
In Vitro Digestion Characteristics of Tilapia Myofibrillar Proteins under Different Heating Conditions
Published 2025-08-01“…This study investigated the effects of three thermal processing methods: Steaming at 100 ℃ for 5 minutes, microwaving at 500 W for 5 minutes, and baking at 160 ℃ for 8 minutes, on the quality of tilapia muscle and protein digestibility. …”
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72687
Characteristics and driving factors of power generation performance in microbial fuel cells: an analysis based on the CNKI database
Published 2025-06-01“…Microbial fuel cells (MFCs) have become one of the most promising technologies in the field of ecology and environmental science due to their dual functions of power generation and pollutant removal. …”
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72688
Trauma-focused dialectical behavior therapy: study protocol for a randomized controlled multi-center trial in online and face-to-face formats
Published 2025-05-01“…However, as with other disorder-specific treatments, the effect sizes of the standard DBT approach are only modest and access to treatment is limited. …”
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72689
Bullying and depression among adolescents in East Asia: a scoping review on prevalence rates, risk and protective factors
Published 2025-03-01“…Psychosocial associations of bullying and depression which were similarly found in Western cultures include individual factors of coping style and gender; family factors of functioning and sibling relationships; and community factors of friendship and school-connectedness. …”
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72690
Peanut leaf transcriptomic dynamics reveals insights into the acclimation response to elevated carbon dioxide under semiarid conditions
Published 2025-03-01“…We tested the hypothesis that maintaining high photosynthesis under long-term elevated [CO2] is associated with the shift in C metabolism gene expression regulation.MethodsWe used a field CO2 enrichment system to examine the effects of elevated [CO2] (ambient + 250 ppm) across different soil water availability and plant developmental stages on the molecular responses in a peanut runner-type genotype. …”
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72691
Positive association between foliar silicon and extrafloral nectar in Vicia faba with application of methyl jasmonate
Published 2025-02-01“…Plants have evolved direct and indirect defences against herbivores, which may come at a cost to other plant functions. Many plants can uptake and deposit large amounts of silicon within plant tissue, creating structures which can reduce herbivore performance. …”
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72692
Synthesis of New Pyrazolo[3,4-<i>d</i>]pyrimidine Derivatives: NMR Spectroscopic Characterization, X-Ray, Hirshfeld Surface Analysis, DFT, Molecular Docking, and Antiproliferative...
Published 2024-10-01“…Geometrical parameters were accurately modeled by DFT calculations using the B3LYP hybrid functional combined with a 6–311++G(d,p) basis set. …”
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72693
Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease
Published 2025-03-01“…Abstract Background Kinesin family member 13B (KIF13B), a crucial motor protein, exerts multiple cellular biological functions. However, the implication of KIF13B in metabolic dysfunction-associated fatty liver disease (MAFLD) has not been explored yet. …”
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72694
3D printing of continuous cotton thread reinforced poly (lactic acid)
Published 2024-12-01“…The functions of the immersion temperature, diameter of CCT and alkali treatment of CCT to the tensile properties of PLA/CCT filament were inspected. …”
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72695
Climate, soil and management factors drive the quantitative relationships between soil fertility and spring maize water productivity in northern China
Published 2025-07-01“…The potential QRs determined by boundary functions were reached up to 6.2, 5.26 and 6.12 kg m−3 in NW, at dry years and under NPK, respectively. …”
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72696
Evaluation of cerebral perfusion heterogeneity by the electrical impedance tomography
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