A miR-JL-5 inhibitor modulates the proliferation of Nosema ceranae in Apis cerana by Xu Han, Xu Han, Jin Hua Xiao, Wei Yu Yan, Xu Jiang He, Xu Jiang He, Zhi Jiang Zeng, Zhi Jiang Zeng

“…Both the biological functions of miR-JL-5 and the target gene of miRNAJL-5, were verified using RNA interference.ResultsOur results showed that expression levels of JL-5 and the spore load in the miRNA inhibitor group were significantly lower than those in the infection and miRNA-scramble groups. …”
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Impact of green and blue spaces on ecosystem services in Beijing: spatiotemporal dynamics and driving mechanisms by Chaonan Cheng, Yang Hu, Feng Li, Ming Zhao, Pei Wang

“…Notably, socioeconomic incentives and green infrastructure governance—especially objective indicators such as forest, garden, and greenspace area—have effectively driven GBS expansion. However, urban expansion has led to pronounced fragmentation of peri-urban GBS, suggesting potential degradation of their ecosystem service support functions. …”
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On the measurement of microclimate by Ilya M. D. Maclean, James P. Duffy, Stef Haesen, Sanne Govaert, Pieter De Frenne, Thomas Vanneste, Jonathan Lenoir, Jonas J. Lembrechts, Marcus W. Rhodes, Koenraad Van Meerbeek

“…The last decade has witnessed a paradigm shift in efforts to quantify these differences and to understand their ecological, functional and evolutionary implications. This renewed interest in microclimate ecology has been accompanied by the development of various compact temperature sensors and radiation shields. …”
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Investigating the Design and Manufacture of a Silicone Texture Pad in a Lumbosacral Orthosis for a Patient With Chronic Low Back Pain by Bahareh Delshad, Mokhtar Arazpour, Akbar Biglarian, Seyed Reza Mousavi, Mohammad Ali Mardani

“…The patient’s pain and functional disability were measured by the visual analog scale (VAS) and Oswestry disability index (ODI) before using the belt, and after 6 weeks of using it, her satisfaction with the treatment method was recorded. …”
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Deciphering the role of Hashimoto's Thyroiditis-related key genes in thyroid cancer via detailed in silico analysis followed by the experimental validation by Mostafa A. Abdel-Maksoud, Taghreed N. Almana, Saeedah Almutair, Abdulaziz Alamri, Ibrahim A. Saleh, Mohamed Y. Zaky, Wahidah H. Al-Qahtani, Yasir Hameed

“…The impact of BRAF overexpression on SW579 cells was assessed through various functional assays. Overexpression of BRAF resulted in reduced cell proliferation, colony formation, and wound healing, which may reflect context-dependent effects. …”
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A qualitative study on optimizing influenza vaccination services and strategies for people aged 60 and above in Shanghai by WANG Xiaolan, YANG Tian, XUE Caoyi, WU Linlin, FEI Yi, YANG Xiaoguang, XU Biao

“…Furthermore, systematic interventions and publicity efforts should be effectively integrated with social media and the functions of neighborhood committees.…”
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The KDM5A/HOXA5 axis regulates osteosarcoma progression via activating the Wnt/β-catenin pathway by Yi Luo, Youzhi He, Yuxia Xu, Yongfu Wang, Li Yang

“…Abstract As an oncogenic driver, lysine-specific demethylase 5A (KDM5A) participates in regulating numerous tumor progression-related processes. Moreover, KDM5A functions as a histone demethylase, modulating the expression levels of its target genes by adjusting methylation levels. …”
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Results of anti-VEGF therapy in patients with uveal melanoma by V.A. Yarovaya, E.O. Malakshinova, V.A. Pismenskaya, R.A. Loginov, A.A. Yarovoi

“…The first experience of using anti-VEGF in our country has shown its effectiveness in reducing the height of macular edema and improving visual functions, which makes their use in radiation retinopathy expedient.…”
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Network pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer by Ma Zushuai, Ji Yanrong, Zhao Chengdu, Zhu Xu, Ding Qianshan

“…In vitro experiments were further performed to investigate the effects of quercetin, one of the main components of CWQ, on CRC cells. …”
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Bioinformatics analysis across pan-cancer and experimental validation in hepatocellular carcinoma revealed the oncogenic role of SF3B6 by Linshuang Tu, Jiefu Luo, Ya Yin, Huihong Yu

“…The elevated expression of SF3B6 demonstrated predictive value for cancer diagnosis, prognosis, and responses to immunotherapy. Functional enrichment analysis suggests that SF3B6 was closely associated with pathways related to tumor immunity, tumor metabolism, and cell cycle. …”
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Results of studying the diabetic retinopathy course in potential kidney and pancreatic recipients while on hemodialysis by I. V. Vorobyeva, E. V. Bulava, A. G. Balkarov, I. V. Dmitriev

“…Against the background of maintenance hemodialysis hemodialysis in patients with terminal diabetic nephropathy, along with a decrease in hyperazotemia, there is an improvement in architectonics, hemodynamics of the retina and visual functions.…”
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A Comparative Study of Taylor Spatial Frame and Monolateral External Fixator for Treating Infected Tibial Defects With Concomitant Soft Tissue Loss by Zhiming Zhao, Guoqi Ji, Chengkuo Cai, Hengsheng Shu, Weiguo Xu

“…Demographic information, wound healing time, bone healing index, external fixation index, cost of hospitalization, and complications were recorded and compared between the two groups. Bone healing and functional recovery were assessed at the last follow‐up (mean 18.8 months postoperatively; range 12–24 months) using the Association for the Study and Application of the Method of Ilizarov criteria (ASAMI) score. …”
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Data Mining–Based Model for Computer-Aided Diagnosis of Autism and Gelotophobia: Mixed Methods Deep Learning Approach by Mohamed Eldawansy, Hazem El Bakry, Samaa M Shohieb

“…This comorbidity can significantly impair the quality of life, particularly in adolescents with high-functioning ASD, where the prevalence reaches 41.98%. …”
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POSSIBILITIES OF DIAGNOSIS OF RADIATION INJURIES AND REHABILITATION OF PATIENTS AFTER COMBINED TREATMENT OF MALIGNANT TUMORS OF THE BREAST by A. V. Kondakov, M. E. Borodina, O. V. Andrianov, N. I. Rozhkova

“…The proposed method of of research of the thermal state of postoperative functional area allows to identify disease and organic components in the form of scars and radiation fibrosis. …”
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The polarity protein Par3 enhances renal cell carcinoma metastasis via YAP/TAZ activation by Soo Lee, Jonathan Balcazar, Karla Davis, Rey-Chen Pong, Jer-Tsong Hsieh, Payal Kapur, Xiaosong Meng

“…Interestingly, Par3’s functions vary among cancers: both Par3 elevation (in the prostate or liver) and loss (in the breast or lung) have been implicated in cancer metastasis. …”
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Exploring exhaled breath biomarkers for lactose intolerance diagnosis: the Lactobreath pilot study protocol by Daniel Pohl, Stamatios Giannoukos, Kathryn Jane Burton-Pimentel, Roxane Guillod, Guy Vergères

“…Diagnosis is complicated as food intolerance is often associated with functional GI disorders, while FODMAPs may exert their effects individually or in combination. …”
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Expression Dynamics and Genetic Compensation of Cell Cycle Paralogues in <i>Saccharomyces cerevisiae</i> by Gabriele Schreiber, Facundo Rueda, Florian Renner, Asya Fatima Polat, Philipp Lorenz, Edda Klipp

“…In addition, we also analyze the effect of the knockout of one part of each pair on the expression of the other gene. …”
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Does weightbearing status impact mortality and other complications in hip fracture patients when accounting for frailty? by Makoa Mau, Tyler Thorne, Kai Rossbach, Eleanor H. Sato, Chong Zhang, Angela P. Presson, Justin M. Haller

“…Controlling for RAI-Rev, age, sex, BMI, functional status, and CPT, weightbearing patients had a 42% lower odds of 30-day mortality (p < 0.001), a 31% lower odds of a SAE (p < 0.001), and a 24% lower odds of a MAE (p < 0.001) in comparison to non-weightbearing patients. …”
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PLZT-Based Shutters for Free-Space Optical Fiber Switching by Fan Zhang, Hsi-Hsir Chou, W. A. Crossland

“…With the increasing demand for optical fiber switching technologies from data center networks, shutter-based free-space optical fiber switching technology is promising for such network applications as the major advantages of this switching technology are that multicast switching, which is a vital functionality required in data center networks, can be easily achieved through its optical fan-out mechanism and that the switching performance can also be significantly strengthened while new materials with a faster response time are used as a spatial light modulator (SLM) to act as shutters. …”
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Optimization of PLGA-Doxorubicin Hybrid Nanoparticles using Design of Experiments: Synthesis, Characterization, and Applications by Adina TURCU-STIOLICA, Andrei BITA, Maria Viorica CIOCILTEU

“… Background and Aim: Poly (lactic-co-glycolic acid) (PLGA) exhibits a range of advantageous properties, including tunable particle sizes, stability, biodegradability, and the potential for surface functionalization. These characteristics have established PLGA as a widely utilized material in drug delivery systems. …”
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