Problems of optimizing the energy consumption of households in the tasks of improving the energy efficiency of the housing sector by G. G. Grebenuk, S. M. Nikishov, A. A. Krygin, L. A. Sereda

“…In the second part, a mathematical model of their  functioning is proposed using examples of specific household  electrical appliances. …”
Get full text

Prevalence of chronic bronchitis against a background of abdominal obesity in young people aged 25–44 in Novosibirsk by Yu. I. Ragino, E. A. Kurtukov, D. V. Denisova, Ya. V. Polonskaya, L. V. Shcherbakova

“…CB was recorded according to standardized epidemiological (questionnaire, pulmonary questionnaire) and functional (spirometry) criteria.Results. The prevalence of AO and CB in the population was 42.9% and 8.7%, respectively; in men 43.2% and 7.7%; in women 42.7% and 9.6%. …”
Get full text

Educational potential of Russian senior citizens by Т. I. Kasyanova, L. I. Voronina, T. M. Rezer

“…Senior people would like their experience, wealth of knowledge and skills to be in demand; they believe that they could perform social roles and functions such as a mentor or consultant in the professional sphere, an adviser in the authorities, an independent expert, etc. …”
Get full text

The influence of the interaction of right ventricle and pulmonary artery system on the development of adverse outcomes in acute decompensation of chronic heart failure by Madina R. Islamova, Ayten F. Safarova, Zhanna D. Kobalava

“…Echocardiography showed more pronounced deviations in the structural and functional parameters of the right and left heart compartments and a higher PA systolic pressure. …”
Get full text

Cyclin D2 – a potential biomarker in uterine corpus endometrial carcinoma through methylation chip and bioinformatic analysis by Lizhen Wang, Lizhen Wang, Wu Qu, Zhifu Yang

“…CCND2 was selected for further functional analysis. IHC results revealed that the positive expression of CCND2 in UCEC was significantly lower than in normal endometrial tissue (P < 0.05). …”
Get full text

Genome-wide DNA methylation analysis of Astragalus on the intervention of ID2 promoter via PI3K/Akt signaling pathway in peritoneal fibrosis by Manshu Yu, Junyi Zhao, Yun Shan, Huibo Dai, Lei Tang, Li Sheng, Lu Zhang, Meixiao Sheng

“…Chromatin immunoprecipitation and luciferase assays were used to identify the prediction of DNA methyltransferase (Dnmts) binding with methylated target gene. The functions of the validated pathways were further investigated using the knockdown or overexpression strategy. …”
Get full text

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis by Vivian I. Ko, Kailee Ong, Deborah Y. Kwon, Xueying Li, Alicia Pietrasiewicz, James S. Harvey, Mukesh Lulla, Guruharsha Bhat, Don W. Cleveland, John M. Ravits

“…However, the treatments did not result in improved functional measurements or in overall survival. Our results demonstrate that phosphorylation contributes to neuronal toxicity and suggest CK1δ/ε inhibition in combination with other therapies targeting TDP-43 pathology could potentially provide therapeutic benefit in ALS.…”
Get full text

Pharmacokinetic Interactions of Phenosanic Acid with Valproic Acid and Carbamazepine in Dogs by M. V. Karlina, V. M. Kosman, V. G. Makarov, M. N. Makarova, S. V. Morozov, E. E. Gushchina, N. V. Zhuravskaya

“…Phenosanic acid prevents convulsions, reduces the frequency of epileptic seizures, and improves cognitive, intellectual and mnestic functions in patients with epilepsy. Therefore, phenosanic acid-based medicinal products are promising candidates for inclusion in combination antiepileptic therapy. …”
Get full text

An efficient propagation system through stem cuttings of a multipurpose plant—Ficus tikoua Bur by Tinghong Tan, Yu Peng, Biling An, Fan Gao, Yanni Sun, Chuandong Yang, Hong Yang, Zhihong Lu

“…To address this, we investigated the effects of habitat heterogeneity, physiological indicators, and environmental factors on the cutting propagation of F. tikoua. …”
Get full text

Institutional conditions of internationalisation of higher education: Mass higher school by D. A. Smaliakou

“…Currently, internationalisation is a priority for the development of higher education, as an institutional component of its academic functioning, both in terms of ensuring the quality of education, and in connection with the implementation of a multi-level integration agenda, in which a modern university is involved. …”
Get full text

Self-directed arm-crank exercise to improve volitional control of the trunk in patients with subacute spinal cord injury: a multicentre, parallel-group, randomised controlled trial... by Tom E Nightingale, Joan L Duda, Shin-Yi Chiou, Eduardo Martinez-Valdes, Zubair Ahmed, Maria del Rocio Hidalgo Mas, Joshua Kearney, Vicki Middleton, Chuang-Yuan Chiu

“…Outcomes include static and dynamic sitting balance with kinematic measurements and high-density electromyography of the erector spinae, corticospinal excitability, muscle strength, functional independence and questionnaires of neuropathic pain, psychological well-being, self-efficacy and motivation, physical activity and health-related quality of life. …”
Get full text

Construction of a reading frame–independent yeast two-hybrid vector system for site-specific recombinational cloning and protein interaction screening by Richard H. Maier, Christina J. Brandner, Helmut Hintner, Johann W. Bauer, Kamil Önder

“…We tested the new vectors within the Y2H system and demonstrated full functionality without any undesired effects on the Y2H system itself. …”
Get full text

CONDITIONS FOR SUCCESS IN APOLOGY SPEECH GENRE by Oleksandra M. Shumiatska

“…It was found that the success or failure of apology can be assessed by analyzing the perlocutionary effect, and violation of the conditions of success can lead to communicative failure, which manifests itself in a negative reaction of the addressee and hinders cooperative interpersonal communication.…”
Get full text

Oral health-related quality of life in Bangladeshi children of sex workers: socio-behavioural and oral health predictors by Afia Mahmuda Khan, Taseef Hasan Farook, Sumaiya Zabin Eusufzai, Mehnaj Sharmin, Sabrin Shohid, Tabassum Zerin, Lameea Shahed, Sheikh Jamal Hossain, Mohammad Delwer Hossain Hawlader

“…Results Among children aged 7 to 11, oral symptoms (Mean = 5.36, SD = 3.72) and functional limitations (Mean = 4.57, SD = 4.42) were the most affected parameters. …”
Get full text

Comprehensive analysis of cholesterol metabolism-related genes in prostate cancer: integrated analysis of single-cell and bulk RNA sequencing by Zixiong Jiang, Yu Luo, Liangdong Song, Jindong Zhang, Chengcheng Wei, Shuai Su, Delin Wang

“…Patients were classified into subgroups using consensus clustering. Functional enrichment and Gene Set Enrichment Analysis (GSEA) were applied to explore the potential pathways. …”
Get full text

Exploring prevention and control mechanisms of youth substance use: a case of North Wollo and Waghimra, Northeast Ethiopia by Sindew Asmare Wedi, Biruk Beletew Abate, Biruk Beletew Abate, Tesfa Anmut Asres, Mohammed Aragaw Abera, Sentayehu Oljira Bekele, Ashenafi Kibret Sendekie, Ashenafi Kibret Sendekie

“…This study recommends making evidence-based interventions and installing functional networks among sectors to deal with common issues. …”
Get full text

The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility in Oryza sativa L by Yusheng Xu, Yusheng Xu, Dingyang Yuan, Meijuan Duan

“…This system comprises three modules: first, a dominant nuclear male-sterile (NMS) functional module driven by p5126, designed to achieve the dominant nuclear male-sterile trait; second, a fluorescence-based selection module driven by the endosperm-specific promoter LTP2, which facilitates the expression of the red fluorescent protein gene DsRed; and finally, a herbicide resistance screening module driven by the constitutive CaMV35S promoter, enabling the expression of the selectable marker Bar gene. …”
Get full text

Optimizing Microbial Composition in Soil Macroaggregates Enhances Nitrogen Supply Through Long-Term Straw Return by Lei Xu, Ganghua Li

“…Our findings indicated that straw return significantly increased mineral N concentrations in soil macroaggregates, with no statistically significant effect observed on microaggregate composition. We observed increased microbial community α-diversity, enhanced co-occurrence network stability, and an increase in functional groups associated with N (nitrate respiration, denitrification, nitrite denitrification) and carbon (saprotrophs, saprotroph–symbiotrophs, patho-saprotrophs) cycling within the aggregates. …”
Get full text

Solid organ transplantation originating from uncontrolled donation after circulatory death in Europe: a narrative review by Yann Pionnier, Tom Darius, Andrea Penaloza, Francoise Steenebruggen, Florence Dupriez, Arne Neyrinck, Cornelia Genbrugge

“…Outcome of uDCD has a lower effectiveness than donation after brain death (DBD) and controlled donation after circulatory death (cDCD) for short term graft survival. …”
Get full text

Scientific and pedagogical staff as a social community in the changing conditions of academic development by G. E. Zborovsky, P. A. Ambarova

“…The study uses the method of analysing statistical data on higher education in Russia and the Ural Federal District for 2000–2021 and Monitoring the effectiveness of universities for 2013–2021.Results. …”
Get full text