Exploring the antimicrobial and antioxidative potential of Leucas aspera (Willd.) link: Phytochemical screening, molecular docking, and HR-LC/MS profiling against SARS-CoV-2 protei... by Thavasiaanatham Seenivasan Shalini, Ragothaman Prathiviraj, Poomalai Senthilraja

“…The methanolic crude extract of L. aspera was further using TLC, FT-IR and HR-LC/MS to identify functional groups and phytocompound present in the extract. …”
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Agent-based modeling of macrophage-fibroblast interactions in the immune response to biomaterials. by Jennifer Riccio, Luca Presotto, Shir Bahiri, Liad Doniza, Donato Inverso, Laura Sironi, Uri Nevo, Giuseppe Chirico

“…They exhibit a variety of functional phenotypes (or states) induced by the stimulus they receive and the microenvironment. …”
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The role of exosomal lncRNAs in mediating apoptosis and inflammation in UV-induced skin photoaging by Kunjie Li, Songfa Lin, Pengjun Zhou, Yanni Guo, Shu Lin, Shu Lin, Chao Ji

“…The skin, as the body’s largest organ, functions as a vital barrier against environmental insults. …”
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The role of vital signs in predicting mortality risk in elderly patients visiting the emergency department by Karin Erwander, Björn Agvall, Kjell Ivarsson

“…These findings highlight the need for more comprehensive, geriatric-informed triage systems that incorporate age-related physiological changes and ensure consistent evaluation of LOC. As frailty and functional status was not available in this dataset, future studies should focus on integrated models that include these factors to improve early risk identification in emergency care for older adults. …”
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Study on the Influence of Sn Concentration on Non-Substitutional Defect Concentration and Sn Surface Segregation in GeSn Alloys by Zihang Zhou, Jiayi Li, Mengjiang Jia, Hai Wang, Wenqi Huang, Jun Zheng

“…To explain these phenomena, we employed first-principles calculations based on density functional theory (DFT) to investigate the effect of varying the total Sn concentration on the formation of substitutional Sn (Sn_s) and VSnV in GeSn alloys, while simultaneously studying the migration kinetics of Sn atoms. …”
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Neurotoxicity associated with cancer chemotherapy: the first study in the Palestinian healthcare system by Roqaya Warrad, Aya Abushar, Abdullah Qubbaj, Sultan Mosleh, Razan Odeh, Ahmad Abuhassan, Ramzi Shawahna

“…Neurotoxicity was evaluated using a comprehensive 65-item functional neurotoxicity scale. Results A total of 196 cancer patients were included in the study. …”
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Realización computacional en tres dimensiones del Método de los Elementos de Contorno en la teoría de la Elasticidad // Three dimension computational realization of the Method of t... by I. L. Alemán Romero

“…</p><p>______________________________________________________________________________</p><p>Abstract<br />In this work is shown the computational formulation in three dimensions of the Boundary Element Method in 3D Elastostatic<br />for isotropic, homogeneous and linear material considering the effect of body forces.<br />The computational formulation of the method is based on the discretization of the boundary into elements over which<br />displacements and tractions are expressed in terms of interpolation functions. …”
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Supporting older adults with mobility disabilities through voice-activated digital assistants and smart home technologies by Jaewon Kang, Emma Lachs, Kathryn Huang, Laura A. Rice, Wendy A. Rogers

“…Qualitative analysis showed that these technologies improved functional independence by enabling participants to control their home environment remotely, increase safety, and enable them to access up-to-date information. …”
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TRPC6-Mediated Zn²⁺ Influx Negatively Regulates Contractile Differentiation of Vascular Smooth Muscle Cells by Chenlin Su, Xinya Mi, Tomoya Ito, Yuri Kato, Akiyuki Nishimura, Ryu Nagata, Yasuo Mori, Motohiro Nishida

“…There were no significant differences in TRPC6-dependent cation currents among all RAoSMCs pretreated with or without TGFβ and/or PPZ2, suggesting that TRPC6 channels are functionally expressed in RAoSMCs regardless of their phenotype. …”
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A Convolutional Neural Network Model for Classifying Resting Tremor Amplitude in Parkinson&#x2019;s Disease by Augusto Ielo, Serena Dattola, Lilla Bonanno, Paolo De Pasquale, Alberto Cacciola, Angelo Quartarone, Maria Cristina De Cola

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RAMP1-dependent hormonal regulation of CGRP and its receptor in the trigeminal ganglion by Anja Holm, Jacob C. A. Edvinsson, Diana N. Krause, Lars Edvinsson

“…WT and Ramp1 KO mice of both sexes were used to explore hormone-dependent gene regulation and RAMP1’s functional role. Results Ramp1 expression varied across the estrous cycle, peaking in proestrus and declining in diestrus, inversely correlated with Calca. …”
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Bidirectional Two-Sample Mendelian Randomization Study Reveals Causal Associations Between Aging and Endometriosis by Chen L, Yan H, Nie J

“…Limei Chen,1,&ast; Han Yan,2,&ast; Jichan Nie2 1Hysteroscoy Center, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai, 200011, People’s Republic of China; 2Department of General Gynecology, Shanghai Obstetrics and Gynecology Hospital, Fudan University, Shanghai, 200011, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Jichan Nie, Shanghai Obstetrics and Gynecology Hospital, Fudan University, 419 Fangxie Road, Shanghai, 200011, People’s Republic of China, Email niejichan@fudan.edu.cnBackground: Previous studies have suggested that aging may influence reproductive functions of female. Nonetheless, the causal relationship between aging and endometriosis has yet to be completely understood.Objective: This study aims to determine whether aging had a causal association with the incidence of endometriosis.Methods: We conducted bidirectional MR analyses to evaluate the causal relationship between aging biomarkers, particularly leukocyte telomere length (LTL), and endometriosis risk. …”
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Transcriptomics Revealed Differentially Expressed Transcription Factors and MicroRNAs in Human Diabetic Foot Ulcers by Vikrant Rai

“…Since proteins are the functional units during biological processes, alteration of gene expression may result in different proteoforms and protein species, making the wound microenvironment a complex protein interaction (proteome complexity). …”
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Improvement of Mechanical Properties of 3D Bioprinted Structures through Cellular Overgrowth by Adrianna Wierzbicka, Mateusz Bartniak, Jacek Grabarczyk, Nikola Biernacka, Mateusz Aftyka, Tomasz Wójcik, Dorota Bociaga

“…The common use of hydrogel materials in 3D bioprinting techniques is dictated by the unique properties of hydrogel bioinks, among which some of the most important in terms of sustaining vital cell functions in vitro in 3D cultures are the ability to retain large amounts of liquid and the ability to modify rigidity and mechanical properties to reproduce the structure of the natural extracellular matrix. …”
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Innovative nanocomposite of intercalated alginate on nanomagnetite@ Al2O3@nanobentonite for uptake recovery of 152–154Eu and 60Co radionuclides from nuclear wastewater by Yasser K. Abdel-Monem, M. I. Ayad, Ayman H. Elewa, Elhassan A. Allam, Mohamed A. Gizawy, Rehab M. El-Sharkawy, Mohamed E. Mahmoud

“…The developed nanocomposite underwent characterization through various techniques, including FT-IR, TGA, SEM, and XRD to refer to an average particle size at 80.0–90.0 nm with numerous related functional groups of its constituting unites. The evaluation of Alg@N-Fe3O4@N-Al2O3 aimed to identify its capacity to uptake and recover two radioactive nuclides, viz. 60Co and 152–154Eu, from nuclear wastewater. …”
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Hyperbranched Thermosensitive Polymer-AuNP Composite Probe for Temperature Colorimetric Detection by Huidong Li, Yao Zhou, Junqi Gu, Wenjie Zhong, Xinlong Li, Xunyong Liu, Zhuhui Qiao, Yi Liu

“…The probe exhibits excellent stability, even at salt concentrations of up to 12 g/L, thanks to the abundant amino functional groups and the large steric hindrance effect unique to HPEI-IBAm. …”
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DNA methylation of food sensitization in a French-Canadian population by Bénédicte L. Tremblay, Anne-Marie Madore, Catherine Laprise

“…This approach provides high-resolution assessment of genome-wide functional methylome that yields valuable understandings to this field of research. …”
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Efficacy and safety of the early implementation of a multimodal rehabilitation program in mechanically ventilated patients: A randomized clinical trial protocol. by Jorge Iván Alvarado Sánchez, Laura Maria Castillo Morales, Yenny Rocio Cardenas Bolivar, Valentina Montañez Nariño, Maria Valentina Stozitzky Ríos, Catherine Lissell Arévalo Guerrero, Miguel Leonardo Pulido Bobadilla, Diana Marcela Melo Rojas, Ana Gabriela López Rubio, Diana Carolina Ortíz Moreno, Paula Andrea Barreto Garzón, Marisol Murillo, Andrés Felipe Mora-Salamanca

“…Early physical therapy in the ICU has shown promise in mitigating these adverse outcomes, yet randomized controlled trials (RCTs) evaluating the combined effects of physical, respiratory, occupational, and speech therapy initiated within the first 24-72 hours are lacking.…”
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Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11 by Li Ling, Jinhe Zhang, Xiao Zhang, Peiqi Wang, Mingjun Ma, Bingling Yin

“…The FTC-133 and TPC-1 cell lines were employed to evaluate the impact of 131I and SAS on cellular functions. Ferrostatin-1 (Fer-1) reversed the cell viability and colony formation ability inhibited by 131I. 131I led to an elevation in the levels of malondialdehyde (MDA), reactive oxygen species (ROS), and lipid peroxidation. …”
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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries by Keith Mitchell, Samuel Hunter, Lutz Froenicke, Karl Murray, Matthew Settles, James S. Trimmer

“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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