Simulation Model to Optimize Turnover Schedule for Train Locomotives by P. A. Kozlov, S. P. Vakulenko

“…It is first time the problem was formulated as a strict optimization model - a dynamic transportation problem. On the functional level, the main goal was to minimize overall costs which are directly related to locomotives operation and to losses due to train delays. …”
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A live online exercise program for older adults improves depression and life-space mobility: A mixed-methods pilot randomized controlled trial. by Giulia Coletta, Kenneth S Noguchi, Kayla D Beaudoin, Angelica McQuarrie, Ada Tang, Meridith Griffin, Rebecca Ganann, Stuart M Phillips

“…We investigated the preliminary effectiveness of a live, online exercise program on community-dwelling older adults' physical activity levels.…”
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Assessing the Impact of Common Cause Failures on Site Risk within Level 1 Multi-Unit PSA by James F. Coleman, Emmanuel K. Boafo, S. Yamoah, F. Ameyaw

“…In conclusion, this study’s findings can help us better understand how CCFs increase multi-unit site risk and can also act as a starting point for future studies on the qualitative and quantitative categorizations of CCF effects within MUPSA.…”
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HSPB1 Orchestrates the Inflammation-Associated Transcriptome Profile of Atherosclerosis in HUVECs by Gang Zhao, Li Zhao, Yulin Miao, Lei Yang, Lizhen Huang, Zhipeng Hu

“…In this study, we aim to explore the functions and downstream targets of HSPB1 in human umbilical vein endothelial cells (HUVECs). …”
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TREATMENT OF HEAD AND NECK SQUAMOUS CELL CARCINOMA ACCORDING ON THE SPECIFIC MOLECULAR FEATURES OF THE TUMOR (A LITERATURE REVIEW) by A. I. Stukan, R. A. Murashko, V. N. Bodnya, O. Yu. Chukhray, E. V. Dulina

“…Target therapy focused on the ways of tumor growth suppression is a much more serious challenge than inhibition of oncogenic signals, because it requires reactivation of tumor suppressors and restoration of their functions, which is more difficult than conventional chemical and biological blockage. …”
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Optimization of Phellinus hartigii extracts: Biological activities, and phenolic content analysis by Orhan Ünal, Ayşenur Gürgen, Tetiana Krupodorova, Mustafa Sevindik, Şanlı Kabaktepe, Ilgaz Akata

“…Abstract Background Medicinal mushrooms are sources of natural substances with diverse biological functions. The study evaluated the biological activity of Phellinus hartigii (Allesch. & Schnabl) Pat. and optimized extraction conditions to the maximize its bioactive potential. …”
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Analysis of PERV-C superinfection resistance using HA-tagged viruses by Merle Flecks, Nicole Fischer, Jacomina Krijnse Locker, Ralf R. Tönjes, Antonia W. Godehardt

“…For PERV, the underlying mechanism is unclear, whether and how cells, that harbor functional PERV, are protected. Using PERV-C(5683) as a reference virus, we investigated SIR in a newly developed in vitro model to pursue the mechanism and confirm its protective effect. …”
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Label-free masterful spectrofluorimetric systems for minuscule tracking of natural antioxidant vincamine in the pharmaceutical, environmental, and biological samples: Comparative g... by Eman Yosrey, Heba Elmansi, Shereen Shalan, Jenny Jeehan Nasr

“…The evaluation showed that the proposed works effectively strike a compromise between sustainability and functionality postulates. …”
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Pan-cancer analysis of ADAR1 with its prognostic relevance in low-grade glioma by Qin Yang, Xin Li

“…These discoveries suggest that ADAR1′s functions may extend beyond our current understanding. …”
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Impact of the alkaline volatile trimethylamine on the physiology of Streptomyces venezuelae: an integrated transcriptomic and metabolomics study by Yanping Zhu, Hanlei Zhang, Meng Liu, Xiuhua Pang

“…ABSTRACT Streptomyces bacteria use volatile compounds for a range of functions, including communication and to kill competing species. …”
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Non-symbiotic N2 fixation is less sensitive to changes in temperature than carbon mineralization in Northern forest soils by Eduardo Vázquez, Marie Spohn

“…Northern forests are characterized by low temperatures that play a key role in the whole ecosystem functioning. However, Northern forests are expected to experience the largest temperature increase of all forest biomes in the next decades, which could affect central ecosystem processes, such as carbon (C) mineralization and N2 fixation. …”
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Extracorporeal life support for severe cardiogenic shock induced by diltiazem intoxication by Srdanović Ilija, Kovačević Mila, Stefanović Maja, Petrović Milovan, Čanković Milenko, Velicki Lazar

“…After the successful restoration of all major organ functions, the patient was successfully decannulated and discharged from the hospital after 10 days in a good condition. …”
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Acute Ischaemic Stroke in Patients Treated with Direct Oral Anticoagulants: Potential Causes, Clinical Characteristics, and Short-Term Outcomes by Katarzyna Sawczyńska, Ewa Włodarczyk, Aleksandra Pawlicka, Bartosz Kołodziejczyk, Paweł Wrona, Kamil Wężyk, Tomasz Homa, Paulina Sarba, Dominik Wróbel, Kaja Zdrojewska, Maria Sobolewska, Dawid Rolkiewicz, Agnieszka Slowik

“…Patients with prestroke DOAC treatment had worse functional condition before stroke and higher stroke severity on admission but similar short-term outcomes and similar short-term effects of treatment with MT. …”
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Active immunization with inhibin DNA vaccine promotes spermatogenesis and testicular development in rats by Jinzhu Meng, Jian Hao Feng, Lilin Xiao, Wanfeng Zhou, Hongliang Zhang, Xianyong Lan, Shuilian Wang

“…These findings illustrate a functional cross-link between FSH, T, LH and spermatogenic markers via inhibin to maintain spermatogenesis. …”
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(-)-Epigallocatechin-3-O-Gallate Regulates Muscle Growth, Antioxidant Status, and Nutritional Composition of Juvenile Common Carp (Cyprinus carpio L.) by Jiali Mi, Dan Liu, Shaoyang Zhi, Xiao Yan, Chaobin Qin, Xinxin Xu, Luming Wang, Guoxing Nie

“…Among the polyphenolic compounds commonly found in green tea, (-)-epigallocatechin-3-gallate (EGCG) is known to have various functions, including the promotion of antioxidant and myofiber growth in mammals. …”
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Selection of appropriate sanitation systems and technology options for urban areas in Kombolcha town Ethiopia by Seid Endris, Tewodrose Desale Meselaw, Tigist Yimer, Almayehu Ali, Anteneh Yayeh, Nurye Mohammed, Metafet Asmare

“…Similar ketenas or Kebeles (the smallest administrative unit within a town or city, typically functioning as a local government or community division) form were merged into groups. …”
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Sistemas de drenagem agrícola. Parte I: desenvolvimento do modelo e análise de sensibilidade Agricultural drainage systems. Part I: model development and sensitivity analysis by João C. F. Borges Júnior, Paulo A. Ferreira, Fernando F. Pruski, Aziz G. da Silva Júnior

“…Using the production functions that consider the stress caused by excess and lack of water in the root zone, this model accomplishes the economic analysis for several configurations of the drainage system, allowing for the determination of the economic spacing among drains besides informing about the economic viability of the enterprise. …”
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Total Arthroscopic Resection of the Talocalcaneal Coalition in Adults: Key Points of Surgical Technique by Yiyuan Sun, Wufeng Cai, Xihao Huang, Jian Li, Qi Li

“…The purpose of this study was to retrospectively evaluate the effectiveness and safety of endoscopic resection of the TCC. …”
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Assessment of hemodynamic parameters of hepatic and visceral blood flow in decompensated liver cirrhosis by A. S. Tugushev, O. S. Cherkovska, D. I. Mikhantiev

“…Decompensation of the disease was associated with progressive reduction in both portal and arterial hepatic blood flow, which were correlated with the severity of functional liver disorders regardless of the complication nature. …”
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Endothelial Microvascular Dysfunction and Its Relationship with Haptoglobin Levels in Patients with Different Phenotypes of Chronic Heart Failure by V. I. Podzolkov, N. A. Dragomiretskaya, I. G. Beliaev, Ju. S. Kucherova, A. V. Kazadaeva

“…Patients with different phenotypes of functional class II-IV chronic heart failure according to NYHA (n=80) underwent a general clinical examination, determination of the serum haptoglobin level by enzyme-linked immunosorbent assay, as well as an assessment of the MC state on the medial surface of the upper third of the leg by laser Doppler flowmetry (LDF).Results. …”
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