Application of Mendelian randomization and bioinformatic analysis to construct a prognostic model for thyroid cancer and perform pan-cancer analysis by Zhenrun Zhan, Zhiyan Weng, Ke Zheng, Jiebin Lin, Sunjie Yan, Ximei Shen

“…Abstract Objective This study aimed to identify causal effects and potential molecular mechanisms of genes associated with THCA development. …”
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Decreased IL-33 Production Contributes to Trophoblast Cell Dysfunction in Pregnancies with Preeclampsia by Hong Chen, Xiaobo Zhou, Ting-Li Han, Philip N. Baker, Hongbo Qi, Hua Zhang

“…To investigate IL-33 effects on trophoblast cells separately, IL-33 shRNA was introduced into HTR8/SVneo cells and villi. …”
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Development of an alkaliptosis-related lncRNA risk model and immunotherapy target analysis in lung adenocarcinoma by Xiang Xiong, Wen Liu, Chuan Yao

“…The progression-free survival (PFS) and overall survival (OS) rates of the low-risk group were significantly higher than those of the high-risk group. The risk signature functions as a prognostic factor that is independent of other variables. …”
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A COVID Support App Demonstrating the Use of a Rapid Persuasive System Design Approach by Rashmi P. Payyanadan, Linda S. Angell, Amanda Zeidan

“…Importantly, this application provides the first concrete example of how the R-PSD framework can be operationalized to produce a functional, user-informed app under real-world time and resource constraints. …”
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Breaking barriers: targeted delivery of resveratrol in lung cancer using folate-integrated and pH-responsive hybrid nanocarriers by Sanjoy Das, Malay K. Das, Taison Jamatia, Nayan Ranjan Ghose Bishwas, Dhritiman Roy, Emdormi Rymbai

“…Working on this rationale, the present study was aimed to develop novel and affordable hybrid nanocarriers combined with folate and pH-responsive functionalities for targeted delivery of Resveratrol (FOL-RSV-LPHNCs). …”
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Neuropeptide S pathway in PTSD and neuropsychiatric disorders: A review by Zhi-cheng Zhu, Xue-jing Han, Zhen He, Meng-yang Liu, Ning Wu, Xiang-min Tong, Fei Li

“…This narrative review surveys studies published 2000–2024 in PubMed, Embase and Web of Science that examine NPS/NPSR involvement in core PTSD features and typical comorbidities. The functional rs324981 A/T polymorphism, which boosts NPSR surface expression and signalling, consistently associates with greater PTSD risk and symptom severity. …”
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Intermittent hypobaric hypoxia and neuroendocrine reaction of the parvocellular neurons of the paraventricular hypothalamic nucleus by V. O. Shamenko, Ye. V. Kadzharian, A. V. Abramov

“…The aim of the research was to study the functional state of the peptidergic neurons of the medial parvocellular nuclei of the paraventricular hypothalamic nucleus (PVHmp) during the multi-day action of intermittent hypobaric hypoxia and in the posthypoxic period. …”
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Selection of single chain antibody fragments binding to the extracellular domain of 4-1BB receptor by phage display technology by Salman Bagheri, Mehdi Yousefi, Elmira Safaie Qamsari, Farhad Riazi-Rad, Mohsen Abolhassani, Vahid Younesi, Ruhollah Dorostkar, Ali Akbar Movassaghpour, Zahra Sharifzadeh

“…The data from this study have provided a rationale for further experiments involving the biological functions of anti-4-1BB single chain variable fragments in future studies.…”
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Psilocybin-assisted therapy for reducing alcohol intake in patients with alcohol use disorder: protocol for a randomised, double-blinded, placebo-controlled 12-week clinical trial... by Claus Thorn Ekstrøm, Patrick MacDonald Fisher, Gitte Moos Knudsen, Dea Siggaard Stenbæk, Anders Fink-Jensen, Mathias Ebbesen Jensen, Tobias Søgaard Juul

“…However, the efficacy of a single psilocybin administration and its potential neurobiological underpinnings still remain unknown.Methods and analysis To establish efficacy, we will investigate the effects of psilocybin-assisted therapy versus placebo in a randomised, double-blinded, placebo-controlled 12-week clinical trial. …”
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Active Seizures Predict Worse Instrumental Activities of Daily Living in Individuals With Normal Cognition and Dementia by Ifrah Zawar, Jaideep Kapur, Meghan M. Mattos, Carol Manning, Syeda Amrah Hashmi, Mark Quigg

“…Methods Pfeffer Functional Activities Questionnaire (FAQ) measured IADLs. …”
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CRNDE alleviates IL-1β-induced chondrocyte damage by modulating miR-31/NF-κB pathway by Jiuxiang Liu, Jiangqi Cheng, Hao Zhou, Qiang Zuo, Feng Liu

“…However, the precise mechanism by which CRNDE affects the physiological functions of OA chondrocytes remains unclear. Methods To simulate the inflammatory conditions observed in OA, interleukin (IL)-1β-stimulated chondrocyte C-28/I2 cells were utilized. …”
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Strategic Doping for Precise Structural Control and Intense Photocurrents Under Visible Light in Ba₂M_0.4Bi_1.6O₆ (M = La, Ce, Pr, Pb, Y)... by Tirong Guo, Wen Tian Fu, Huub J. M. de Groot

“…Developing functional perovskites is important for advancing solar energy conversion technologies. …”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…Cell counting kit-8 (CCK-8) assay, colony formation assay, flow cytometry, wound healing assay, and Transwell assay were conducted for in vitro functional experiments. In vivo experiments involved subcutaneous tumor formation in nude mice. …”
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Intermittent fasting and a no-sugar diet for Long COVID symptoms: a randomized crossover trial by Thomas Bunker, Benjamin D. Horne, Mark D. Baldwin, Robert Sorrells, Sabrina Turner, Laynee Laube, Ari Solomon, Lucy A. Horne, Jeffrey Novack

“…Abstract Long COVID (LC) is a common chronic health condition that impairs daily functioning and social connections. This is the first randomized clinical trial to directly compare the effect of two Intermittent Fasting regimens on LC symptoms. …”
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Small Extracellular Vesicle (sEV) Uptake from Lung Adenocarcinoma and Squamous Cell Carcinoma Alters T-Cell Cytokine Expression and Modulates Protein Profiles in sEV Biogenesis by Hafiza Padinharayil, Jinsu Varghese, Pulikkottil Raphael Varghese, Cornelia M. Wilson, Alex George

“…This study examines the immunomodulatory effects of sEVs derived from lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) on T cells. …”
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Visual Outcomes and Safety Profile of “Dropless Vitrectomy” for Epiretinal Membranes by Chalam KV, Cheng AMS, Gasparian S

“…Tri-Moxi group demonstrated superior anatomical outcomes and comparable functional outcomes while simplifying postoperative care and reducing the occurrence of cystoid macular edema compared to standard topical therapy.Keywords: central macular edema, drop less, epiretinal membrane, inflammation, moxifloxacin, triamcinolone acetonide, vitrectomy surgery, wound healing…”
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Clinical usefulness of hemoencephalography beyond the neurofeedback by Serra-Sala M, Timoneda-Gallart C, Pérez-Álvarez F

“…It is available to any research group for its relative simplicity and low cost and is a useful tool for assessing prefrontal-dependent functions. Older teenagers pose peculiarities in the prefrontal maturation, and we aim to establish HEG patterns that might have clinical applicability. …”
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Ghrelin Immunoreactive Cell Amounts in the Abomasum in 4-Month-Old Calves by Feeding Different Amounts of Prebiotics and New Synbiotics by Astra Arne, Aija Ilgaza, Liga Astra Kalnina

“…In the gastrointestinal system, ghrelin affects multiple functions, including secretion of gastric acid, gastric motility, and pancreatic protein output. …”
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Application of multi-layer chitosan-based wound dressings in dentistry by Alexandr S. Gumenyuk, Denis I. Ushmarov, Sergey E. Gumenyuk, Tatyana V. Gaivoronskaya, Alexandr S. Sotnichenko, Karina I. Melkonyan, Yulia A. Belich, Timofey E. Grigoriev

“…This dressing has a dense outer layer, which structure retains frame functions for a long time, thus providing proper drainage of the pathological focus. …”
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Comparative antioxidant and antimicrobial activities of Nigella sativa flower, leaf, stem, and seed derived silver nanoparticles by Fizza Perveen, Fakhria A. Al-Joufi, Rabia Zeb, Naila Qamar, Abdul Jabbar, Muhammad Naveed Umar, Muhammad Zahoor

“…The presence of organic functional groups in the FTIR spectra confirmed the involvement of plant phytochemicals in fabrication of nanoparticles. …”
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