Single-cell transcriptomics identify a chemotherapy-resistance related cluster overexpressed CLIC3 in ovarian cancer by Zhefeng Li, Jie Li, Yue Li, Junjie Yi, Xiaoting Zhao, Wentao Yue

“…Using GSVA and cell communication analysis, we explored the unique biological functions and communication characteristics of this resistant subcluster. …”
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Associations of Combined Exposure to Metabolic and Inflammatory Indicators with Thyroid Nodules in Adults: A Nested Case-Control Study by Xin-Yi Zhu, Xing-Chen Meng, Bei-Jing Cheng, Chun Wang, Jia Wang, Tian-Lin Li, Hui Li, Ke Meng, Ran Liu

“…Univariate exposure-response functions from BKMR models showed similar results. …”
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m6A-modified lncRNA GAS5 promotes M1-polarization of microglia in alcohol use disorder by Shuang Zhu, Peng Wang, Jian Hu

“…Detection of GAS5 N6-methyladenosine (m6A) modifications, facilitated by alkylation repair homolog 5 (ALKBH5), was performed using RNA immunoprecipitation and RNA pull-down assays. The effect of GAS5 on the functionality of SH-SY5Y cells was evaluated using CCK-8 and Transwell assays. …”
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Comparative evaluation of machine learning models for enhancing diagnostic accuracy of otitis media with effusion in children with adenoid hypertrophy by Xiaote Zhang, Qiaoyi Xie, Ganggang Wu

“…SHAP analysis identified the adenoid-to-nasopharyngeal ratio as the predominant diagnostic indicator, followed by tympanometric type and history of recurrent respiratory infections.ConclusionAn RF-based diagnostic model effectively identifies OME in AH children by integrating anatomical, functional, and inflammatory parameters, providing a clinically applicable tool for enhanced diagnostic accuracy and evidence-based management decisions.…”
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The Impact of Trachomatous Trichiasis on Quality of Life: A Case Control Study. by Esmael Habtamu, Tariku Wondie, Sintayehu Aweke, Zerihun Tadesse, Mulat Zerihun, Zebideru Zewudie, Wondimu Gebeyehu, Kelly Callahan, Paul M Emerson, Hannah Kuper, Robin L Bailey, David C W Mabey, Saul N Rajak, Sarah Polack, Helen A Weiss, Matthew J Burton

“…<h4>Background</h4>Trachomatous trichiasis is thought to have a profound effect on quality of life (QoL), however, there is little research in this area. …”
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Artificial Intelligence Technology Based on Deep Learning in Building Construction Management System Modeling by Hongbo Wang, Yan Hu

“…The results show that this technology can effectively improve the efficiency of the building construction schedule management. …”
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Digital Twin-Based Technical Research on Comprehensive Gear Fault Diagnosis and Structural Performance Evaluation by Qiang Zhang, Zhe Wu, Boshuo An, Ruitian Sun, Yanping Cui

“…Taking the QPZZ-ii gearbox test bed as the physical entity, the research establishes a five-layer architecture: functional service layer, software support layer, model integration layer, data-driven layer, and digital twin layer, forming a closed-loop feedback mechanism. …”
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Life cycle assessment for calcination process of flue gas desulfurization gypsum and transformation into β-CaSO4·0.5H2O by Payal Bakshi, Asokan Pappu, Dhiraj Kumar Bharti

“…Aspect ratio of calcined FGD gypsum samples is reduced from 2.40 to 1.32 due to crack bursting at high temperature and removal of hydroxyl functional group. Environmental impact of calcination process is evaluated by life cycle assessment method using openLCA software and ecoinvent database in conformance with ISO 14040–14044. …”
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Spatial heterogeneity of forest carbon stocks in the Xiangjiang river Basin urban agglomeration: analysis and assessment based on the multiscale geographically weighted regression... by Yingfeng Kuang, Xiaolong Chen

“…This finding provides a crucial scientific basis for the management and ecological protection of forest resources in the Xiangjiang River Basin.ConclusionThis study effectively reflects the spatial relationship between forest carbon stocks and variables through the geographically weighted regression method and the selection of appropriate spatial kernel functions, enhances the estimation accuracy of the spatial distribution of large-scale forest carbon stocks, and accurately reveals the spatial distribution pattern of forest carbon stocks in the Xiangjiang River Basin. …”
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Global research trends and hotspots in Parkinson’s disease psychosis: a 25-year bibliometric and visual analysis by Jianhong Wu, Xin Jin, Weiming Xie, Liang Liu, Fei Wang, Ling Zhu, Yuan Shen, Linghe Qiu

“…Among them, pimavanserin, risk, and functional connectivity have been the most studied areas in the past 7 years and are likely to remain key topics in future research.ConclusionResearch on PDP has garnered increasing attention. …”
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UFLPlus: An Underwater Fish Lamp Technology as an Innovation of Fish-Luring Aids on Boat Lift Net by Fajriah Fajriah, Ahmad Mustafa, Muhammad Rais, La Anadi, Kobajashi Togo Isamu, Marsuki Iswandi, Idrus Salam, Sampunur Sampunur

“…UFLPlus was capable of functioning as an underwater immersion lamp that attracts fish attention and directly monitors the arrival of fish in the water in the fishing area.…”
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Development of a Single-Row Ear Seeder Equipped with a Disk-Cassette Sowing Device by M. M. Shaykhov, A. S. Chulkov, A. V. Podzorov, A. Kh. Tekushev, T. V. Chaplygina

“…(Results and discussion) A prototype single-row ear seeder has been developed and manufactured. The functionality and performance of the disk-cassette sowing device have been evaluated and verified. …”
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CD44 on cancer stem cell is a potential immunological and prognostic pan-cancer biomarker by Ya-Juan Zhu, Si-Ying Li, Shan-Shan Yang, Yang Du, Zhuo-Yuan Zhang, Ji-Yan Liu

“…Furthermore, we verified the effect of CD44 on tumor growth and immune microenvironment in mouse xenografted with shRNA-CD44 MC38. …”
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CHANGES IN THE MOLECULAR GENETIC PROFILE OF INNATE IMMUNE MOLECULES IN INDIVIDUALS WHO HAVE HAD COVID-19 DISEASE by N. D. Abramova, N. O. Kalyuzhnaya, E. A. Meremianina, E. A. Bogdanova, M. P. Kostinova, O. A. Sviticha

“…Since then it was revealed that the severity of the disease pathology may depend not only on the viral strain, but also on the functioning of the immune system. Target. To study characteristics of expression and genetic factors of innate immunity in patients who have had COVID-19. …”
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Multi-scenario analysis of green water resource efficiency under carbon emission constraints in the Chengdu-Chongqing urban agglomeration, China: A system dynamics approach by Keyao Yu, Zhigang Li

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Melanophilin inhibit the growth and lymph node metastasis of triple negative breast cancer via the NONO-SPHK1-S1P axis by Xing Yao, Tan Yuen, Chen Qingchuan, Zhang Jianjun, Liu Yefu, Sun Shulan

“…Protein mass spectrometry was utilized to analyze the protein which interacts with MLPH, and RNA binding protein immunoprecipitation and quantitative real-time PCR (RIP qPCR) were utilized to verify the regulation of sphingosine kinase 1 (SPHK1) expression by MLPH through Non-POU domain-containing octamer-binding protein (NONO). Cell functional assays and in vivo models experiments further confirmed the effects of MLPH on proliferation and lymph node metastasis of TNBC through the SPHK1-S1P axis. …”
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Transcription factor NFKB1 mediates TUBB6 to promote the proliferation and suppress apoptosis in glioma via Wnt/β-catenin signaling pathway by Yan Li, Ziyu Shao, Jun Jiang, Hongyan Wang, Mei Zhang

“…Our findings suggest that TUBB6 contributes to glioma malignancy through its effects on the Wnt/β-catenin pathway. In conclusion, TUBB6 emerges as a promising biomarker for glioma diagnosis and prognosis. …”
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Investigation the Impact of SnO2 Additive on the Structural, Optical, Electrical and Gas Sensing Characteristics of LaCrO3 Perovskite by Uglal Pandit Shinde, Somnath Bhika Handge, Dharma Kisan Halwar

“…This study investigates the effect of SnO2 as an additive on the structural, electrical, optical, and gas sensing properties of LaCrO3 nanoparticles.  …”
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Double-negative T cells in combination with ursodeoxycholic acid ameliorates immune-mediated cholangitis in mice by Chunpan Zhang, Guangyong Sun, Hua Jin, Yunxiong Wei, Shimeng Zheng, Xiyu Wang, Xinyan Zhao, Dong Zhang, Jidong Jia

“…In addition, DNT exhibited a strong killing effect on liver T cells and strong inhibition of their proliferation, but did not significantly improve the histology of PBC liver. …”
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Bond Behavior and Interaction Mechanism Between Metal Ce-Fe by Kai ZHANG, Chang-shui WANG

“…By using vacuum distillation to refine and purify metals, some escaped metals may deposit on the inner walls of vacuum chambers and pipelines. In order to effectively remove residual metals, it is necessary to clarify the bonding behavior and mechanism between metals, providing important theoretical basis for the screening of subsequent metal wiping aids. …”
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