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71581
Neuromonitoring with near-infrared spectroscopy (NIRS) in aneurysmal subarachnoid haemorrhage: a systematic review protocol
Published 2020-11-01“…We will identify all observational and interventional human studies of adult patients hospitalised after aSAH that were monitored using NIRS. Functional outcome measures, including the modified Rankin Scale, the Glasgow Outcome Scale and the Barthel Index, will constitute the primary outcome. …”
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71582
Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia
Published 2025-06-01“…This study investigates the expression and functional significance of CRGs, particularly PDHA1, in AML progression and cuproptosis regulation Methods We integrated bioinformatics analysis and experimental validation. …”
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71583
A prognostic model for head and neck squamous cell carcinoma based on radiotherapy sensitivity insights from nasopharyngeal carcinoma
Published 2025-05-01“…Methods Differentially expressed genes (DEGs) associated with radiotherapy response were identified using the GSE48501 dataset, primarily derived from NPC. Functional annotation was performed via Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses. …”
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71584
Few-Shot Evaluation of Vision Language Models for Detecting Visual Defects in Autonomous Vehicle Software Requirement Specifications
Published 2025-01-01“…Software Requirements Specifications (SRS) are crucial for defining system functionality, constraints, and objectives, particularly in safety-critical applications like autonomous vehicles (AV). …”
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71585
Optimization of the encapsulation of arazá pulp by spray drying: Physicochemical, morphological and in vitro digestion studies
Published 2025-06-01“…This study presents an optimized method to obtain microencapsulates from arazá pulp (not obtained before), with a great potential for the development of functional foods.…”
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71586
Impact of experimental inflammation on the neuronal processing of cardiac interoceptive signals and heart rate variability in humans
Published 2025-07-01“…In neuroimaging research, heartbeat-evoked potentials (HEP) - defined as event-related potentials time-locked to electrocardiogram (ECG) R-waves during electroencephalogram (EEG) recordings - have emerged as a promising metric for cardiac interoceptive processing. We analyzed the effects of intravenous administration of lipopolysaccharide (LPS; 0.4 ng/kg) or placebo, on HEP amplitudes and ANS functioning in healthy, female participants (n = 52) during 8 min resting-state EEG and ECG recordings before and 2 h after injections. …”
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71587
Patients’ satisfaction and efficacy of modern conventional hearing aids: A comprehensive analysis of the self-reported user experiences in adult people
Published 2025-05-01“…Objective: Hearing loss is a widespread condition that impacts the quality of life, affecting communication, social interactions, and cognitive functions. This study aimed to evaluate the subjective benefit and satisfaction of using hearing aids among patients since the adoption rate of hearing aids remains low. …”
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71588
S100A4 contributes to colorectal carcinoma aggressive behavior and to chemoradiotherapy resistance in locally advanced rectal carcinoma
Published 2024-12-01“…Abstract To investigate the functional role of S100A4 in advanced colorectal carcinoma (Ad-CRC) and locally advanced rectal carcinoma (LAd-RC) receiving neoadjuvant chemoradiotherapy (NCRT). …”
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71589
Single-cell and machine learning integration reveals ferroptosis-driven immune landscapes for melanoma stratification
Published 2025-08-01“…A 40-gene prognostic signature (externally validated) effectively stratified patient survival risk and predicted chemotherapy sensitivity. …”
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71590
Assessment of efficacy of platelet-rich plasma application in regeneration of the facial nerve in rabbits
Published 2023-01-01“…The injuries of the facial nerve lead to paralysis of the mimic musculature, which is conditioned by functional disorders accompanied by deformity of varying degrees depending on the intensity and location of the injury. …”
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71591
Transcriptomic Profiling Reveals the Involvement of the Phenylpropanoid–Lignin Pathway in the Response of Maize Roots to Zinc Stress
Published 2025-05-01“…Zinc (Zn) is an essential micronutrient required for plants to perform various metabolic functions, and plant responses to Zn deficiency have been extensively studied. …”
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71592
Pan-cancer analysis of oncogenic role of MAGOH and experiment validation in hepatocellular carcinoma
Published 2025-07-01“…Besides, we validated the clinical significance and biological functions of MAGOH in HCC via clinical specimens and in vitro experiments. …”
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71593
Empirical Analysis of Data Sampling-Based Decision Forest Classifiers for Software Defect Prediction
Published 2025-03-01“…Specifically, this study evaluates the cost-sensitive forest (CS-Forest), forest penalizing attributes (FPA), and functional trees (FT) as DF models. These models were further enhanced using homogeneous ensemble techniques, such as bagging and boosting techniques. …”
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71594
Framework for early assessment of food safety hazards in the transition to a more sustainable food system: three case studies in the Vietnamese Mekong Delta
Published 2025-10-01“…Food production in delta areas such as the Vietnamese Mekong Delta (VMD) faces pressures from climate change effects, primarily salinity intrusion and drought. …”
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71595
Lipid-Lowering Potential of Almond Hulls (Quercetin, Baicalein, and Kaempferol): Insights from Network Pharmacology and Molecular Dynamics
Published 2025-06-01“…Network pharmacology and in vitro studies suggest almond hull extract modulates PI3K-AKT signaling and improves insulin resistance, demonstrating lipid-lowering effects. These findings support its potential in functional foods and pharmaceuticals, though further in vivo validation and mechanistic investigations are required.…”
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71596
Exploring the connectivity of dorsolateral prefrontal cortex and the modulatory impact of transcranial magnetic stimulation in adolescents with depression: a focus on pain-related...
Published 2024-11-01“…Methods Using neuroimaging data, we first compared functional connectivity (FC) of DLPFC between 60 adolescents with depression and 65 controls. …”
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71597
Endocannabinoid system modulation for visceral abdominal pain in inflammatory bowel disease and irritable bowel syndrome: A protocol for systematic review and meta-analysis [versio...
Published 2025-07-01“…Secondary outcomes will include any change in pain intensity, physical and emotional functioning, fatigue and sleep measures, quality of life, gastrointestinal disease or symptom severity, and adverse effects. …”
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71598
Enhancing Ion Transport in Polymer Electrolytes by Regulating Solvation Structure via Hydrogen Bond Networks
Published 2025-06-01“…Computational modeling confirms that the introduced H–bonds effectively modulate the Li<sup>+</sup> coordination environment, promote salt dissociation, and create favorable pathways for faster ion transport decoupled from polymer chain motion. …”
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71599
Investigation of the stemness and wound-healing potential of long-term cryopreserved stromal vascular fraction cells
Published 2025-06-01“…Importantly, the L-SVF group showed significantly improved wound healing compared with the control group, although the wound-healing effect of L-SVF was inferior to that of the S-SVF. …”
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71600
Radiotherapy and breast cancer: finally, an lncRNA perspective on radiosensitivity and radioresistance
Published 2024-09-01“…Nevertheless, RT has two major problems: side effects and radioresistance. Given that patients respond differently to RT, it is imperative to understand the molecular mechanisms underlying these differences. …”
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