Povidone-iodine nasal spray (Nasodine®) for the common cold: a randomized, controlled, double-blind, Phase III clinical trial by Thomas M. Polasek, Peter L. Friedland

“…Nasodine was well tolerated, with mild transient nasopharyngeal discomfort being a common adverse effect.ConclusionNasodine treatment had a consistently positive and clinically meaningful benefit on overall cold severity when compared with saline nasal spray. …”
Get full text

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol by Akash Kumar, Raja Gopal Rayavarapu

“…To overcome these limitations, there is a critical need for the development of an easy-to-use, dual-functional, linker-free nanosystem capable of simultaneous detection of heavy metals and efficient degradation of 4-NP. …”
Get full text

Prediction of technological properties of wheat flour by combination of UV-VIS-NIR spectroscopy and multivariate analysis methods by R. A. Platova, E. V. Zhirkova, D. A. Metlenkin, A. A. Lysenkova, Yu. T. Platov, V. A. Rassulov

“…UV-VIS-NIR spectra contain information on the combination and intensity of absorption bands assigned to functional groups of the composition components and determining the technological properties of wheat flour. …”
Get full text

Suppression of lncRNA OIP5-AS1 Attenuates Apoptosis and Inflammation, and Promotes Proliferation by Mediating miR-25-3p Expression in Lipopolysaccharide-Induced Myocardial Injury by Jiaju Ma, Hebu Qian, Han Zou

“…The purpose of our study was to investigate the functional mechanisms of OIP5-AS1 and miR-25-3p in LPS-induced myocardial injury. …”
Get full text

Interleukin-17 prevents oxidative stress from damaging osteoblast formation by inhibiting autophagic degradation of metallothionein-2 by Xueyan Ling, Cuixia Wang, Qin Feng, Tao Zhang

“…Interleukin 17A (IL-17A) is a key cytokine promoting osteoblast formation, which contributes to osteogenesis. IL-17A functions in autophagy inhibition within osteoblasts. …”
Get full text

Comparative miRNome analysis of colostrum- and mature milk–derived extracellular vesicles from Holstein and Jersey cows by Daye Mun, Sangdon Ryu, Dong-Hyun Lim, Sangnam Oh, Younghoon Kim

Get full text

Energy storage modification of coal gangue and its application in high-specific-energy batteries by Zhihui SUN, Yunbo WANG, Shuxuan MA, Meng LI

“…The results indicate that: After modification treatment, a layer of amorphous nano particle Al2O3 activation layer was formed on the surface of coal gangue, effectively reducing energy loss during the electrode reaction process; The surface of modified coal gangue is rich in highly active electrocatalytic sites such as oxygen-containing functional groups and oxygen vacancies, significantly reducing the activation energy of surface reactions. …”
Get full text

Time-Delayed Cold Gelation of Low-Ester Pectin and Gluten with CaCO₃ to Facilitate Manufacture of Raw-Fermented Vegan Sausage Analogs by Maurice Koenig, Kai Ahlborn, Kurt Herrmann, Myriam Loeffler, Jochen Weiss

“…Gluten as well as pectin had a significant influence on the functional properties of the matrices, especially water holding capacity (increasing with higher pectin or gluten content), hardness (increasing with higher pectin or gluten content), tensile strength (increasing with higher pectin or gluten content) and cohesiveness (decreasing with higher pectin or gluten content). …”
Get full text

Stability and Survivability of Alginate Gum-Coated Lactobacillus rhamnosus GG in Simulated Gastrointestinal Conditions and Probiotic Juice Development by Umair Ali, Muhammad Saeed, Zulfiqar Ahmad, Faiz-ul-Hassan Shah, Muhammad Adil Rehman, Tahir Mehmood, Muhammad Waseem, Hammad Hafeez, Muhammad Azam, Afzal Rahman

“…Hence, encapsulated probiotics can be used for functional beverage development to take advantage of their therapeutic benefits.…”
Get full text

Melanin‐based color variation in response to changing climates in snakes by J. Goldenberg, K. Bisschop, G. Bruni, M. R. Di Nicola, F. Banfi, F. P. Faraone

Get full text

Whole Genome Analysis of Levilactobacillus brevis PL6-1 and Assessment of Its Safety and Antioxidant Activity by LI Yaxin, GU Yunjing, CHENG Weiye, WANG Xuan, ZHANG Qingyang, GONG Hansheng, JIANG Lili, LIU Wenli, LIU Xiaoping, LI Huamin

“…The findings from this study provide a significant theoretical basis for the safe application of this strain in the food industry while establishing a scientific foundation for the development and utilization of its probiotic functions.…”
Get full text

Integrating Genetic and Single‐Cell Genomic Data to Reveal Brain Cell‐Specific Regulation of Attention‐Deficit/Hyperactivity Disorder Risk in the Prefrontal Cortex by Jiawei Gui, Ziyi Xia, Keqi Wan, Xiangli Dong, Weiming Sun

“…We also examined the association between brain cell‐type proportion and ADHD risk and used bioinformatics analyses to explore risk gene functions and identify potential drug‐repurposing targets. …”
Get full text

The Health‐Related Quality of Life for Cemented Versus Uncemented Hemiarthroplasty in Elderly Patients With Femoral Neck Fractures: A Systematic Review and Meta‐Analysis of Randomi... by Mohanad Samaheen, Maen Mohammad, Mikhail Salzmann, Nikolai Ramadanov

“…This systematic review and meta‐analysis aims to compare the effects of the two surgical options on health‐related quality of life (HRQoL), mortality, and functional outcomes. …”
Get full text

Expanding a Health Technology Solution to Address Therapist Challenges in Implementing Homework With Adult Clients: Mixed Methods Study by Brian E Bunnell, Kaitlyn R Schuler, Julia Ivanova, Lea Flynn, Janelle F Barrera, Jasmine Niazi, Dylan Turner, Brandon M Welch

“… BackgroundHomework is implemented with variable effectiveness in real-world therapy settings, indicating a need for innovative solutions to homework challenges. …”
Get full text

Grey Wolf Optimization- and Particle Swarm Optimization-Based PD/I Controllers and DC/DC Buck Converters Designed for PEM Fuel Cell-Powered Quadrotor by Habibe Gursoy Demir

“…Both optimizers work together in the system and try to minimize tracking errors while also minimizing power consumption by using suitable objective functions. Simulation results demonstrate the effectiveness of the PSO- and GWO-based design of the controllers and converters in enhancing energy efficiency and improving the quadrotor’s flight stability. …”
Get full text

CLINICAL NUTRITION INVOLVING A SPECIALIZED PROTEINAND CALORIE-RICH PEDIATRIC MILK PRODUCT FOR ENTERAL FEEDING OF INFANTS WITH PROTEIN-CALORIE DEFICIENCY by L. S. Namazova-Baranova, T. V. Turti, O. L. Lukoyanova, E. P. Zimina, I. A. Belyayeva, A. A. Gorbachyova

“…High tolerability of the formula under analysis was registered in most patients. Termination of functional gastrointestinal tract disorders (posseting, colics, flatulence, constipations) was observed in 23 (87%) patients. …”
Get full text

Seismic Vulnerability Assessment of Residential RC Buildings in Yemen Using Incremental Dynamic Analysis (IDA) by Amr Ahmed Radman Ahmed, Linfeng Lu, Bo Li, Wei Bi, Fawziah Mohammed Abdullah Al-Dhubai

“…Based on these results, cumulative distribution functions (CDFs) were calculated to derive the seismic fragility curves. …”
Get full text

Household ownership of latrines does not ensure use: a scoping review by Nicolas Gaffan, Cyriaque Degbey, Alphonse Kpozehouen, Moussiliou Noël Paraïso, Yolaine Glele Ahanhanzo

“…Some latrine attributes (age, level of household member involvement in construction, hand hygiene facilities, geographical accessibility, functionality, maintenance, cleanliness, type, superstructure, condition, etc) influenced latrine utilisation. …”
Get full text

Applications of biopolymer scaffolds for intestinal delivery of drug-loaded nano-biomaterials: a review by Onkar Kadam, Rutuja Gumathannavar, Kausani Basu, Neha Saini, Nidhi Sapre, Shashwati Wankar, Tahsin Bennur, Atul Kulkarni

“…Thus, from precision medicine and regenerative approaches, intestinal scaffolding may change oral drug administration, improving therapeutic outcomes in patients with gastrointestinal disorders while minimizing systemic side effects.…”
Get full text

Role of IL-17a in the Pathogenesis of Celiac Disease:  A Case–Control Study by Fatima Ali Khudair, Thanaa Shams Aldeen

“…Interleukin 17A (IL-17A) is a multifaceted pro inflammatory cytokine essential for vital functions such as host immunological defense, tissue healing, and the pathogenesis of inflammatory diseases. …”
Get full text