Pedunculopontine-stimulation obstructs hippocampal theta rhythm and halts movement by Jaspreet Kaur, Salif A. Komi, Oksana Dmytriyeva, Grace A. Houser, Madelaine C. A. Bonfils, Rune W. Berg

“…Abstract While the movement of rodents can be paused by optogenetic stimulation of a brainstem nucleus, the pedunculopontine nucleus (PPN), it is unknown whether this response has a functional purpose. The arrest appears conspicuously similar to fear-induced freezing behavior and could constitute a general halting mechanism for movement without an emotional component. …”
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Impact of Parkinson's Disease-Related Dysphagia Severity on Quality of Life: Comparison Between Self-Reports and Videofluoroscopic Swallowing Study Results by Serkan Bengisu, Merve Savaş, Demet Aygün, Senanur Kahraman Beğen, Tutku Altıntaş, Burak Manay

“…The data obtained with VFSS were scored using the Penetration Aspiration Scale (PAS) and Functional Oral Intake Scale (FOIS) by an SLP blinded to patient information and clinical assessment methods. …”
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Popularization of national heritage on the example of creating a digital media genre product – an educational computer game by Uliana P. Efremova, Valeriia M. Kamaeva, Olga A. Tsesevichene, Alexandra D. Shumailova

“…The clear, visual form of quality visual design supports its content and functionality. The article discusses the key stages of creating a game design project. …”
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Peculiarities of Improving Surgical Treatment of Wounds With Full-Thickness Skin Autografts by S. B. Bogdanov, V. A. Aladina, M. L. Mukhanov, S. L. Zaitseva, V. S. Dutov, D. S. Zakeryaeva

“…We found statistically significant differences when comparing the groups using the Kruskal-Wallis test (P < .0001).Conclusions: New developed methods for full-thickness skin autografting in patients with granulation tissue and scar deformities can significantly increase the treatment effectiveness.…”
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Development of a Rapid UPLC Method for Analysis of Carotenoids in Goji Berry Extract and Evaluation of Their Transformation Affected by Saponification by Bo-Yang Hsu, Chia-Hui Lin, Tsai-Hua Kao

“….), also known as wolfberry, is a traditional Chinese medicinal herb widely utilized as a functional food ingredient throughout East Asia. In this study, we developed a rapid high performance liquid chromatography-diode array detection (HPLC-DAD) method for the simultaneous separation of carotenoids in goji berries. …”
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A Fractional Time–Space Stochastic Advection–Diffusion Equation for Modeling Atmospheric Moisture Transport at Ocean–Atmosphere Interfaces by Behrouz Parsa Moghaddam, Mahmoud A. Zaky, António Mendes Lopes, Alexandra Galhano

“…By synthesizing fractional calculus, advective transport mechanisms, and pink noise stochasticity, the proposed model captures the intricate interplay between temporal memory effects, non-local turbulent diffusion, and the correlated-fluctuations characteristic of complex ocean–atmosphere interactions. …”
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The use of a hemoperfusion column that removes endotoxin and cytokines in the complex therapy of widespread peritonitis complicated by septic shock by M. I. Gromov, L. P. Pivovarova, I. V. Osipova, O. B. Ariskina, A. V. Fedorov

“…Over the next 5 days, impaired organ functions gradually recovered (SOFA dynamics from 10 to 1 point) and the level of procalcitonin in the blood decreased from 98 to 5 ng/ml. …”
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Optimization of thermosonication conditions for critical quality parameters of watermelon juice using response surface methodology by Makaepea M. Maoto, Daniso Beswa, Afam I. O. Jideani

“…According to the findings, thermosonication could be a viable method for preserving watermelon juice, with minimal quality loss and improved functional attributes.…”
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TcPO2 as a Predictor of Limb Salvage or Amputation in Patients of Critical Limb Ischemia by Rahul Merkhed, Vikram Patra, Rishi Dhillon, Rohit Mehra, CVNM Dattatreya, Ramandeep Kaur, Gagandeep Singh Vohra, Surjeet Dwivedi

“…Introduction: Critical limb-threatening ischemia presents a significant challenge in clinical management, often necessitating lower limb amputation if not managed promptly and effectively. A crucial aspect of managing CLTI involves determining the optimal level of amputation to maximize post-surgical healing and functional outcomes. …”
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Tuberculosis severity associates with variants and eQTLs related to vascular biology and infection-induced inflammation. by Michael L McHenry, Jason Simmons, Hyejeong Hong, LaShaunda L Malone, Harriet Mayanja-Kizza, William S Bush, W Henry Boom, Thomas R Hawn, Scott M Williams, Catherine M Stein

“…All three SNPs are in introns of RGS7BP and have effect sizes corresponding to clinically meaningful reductions in disease severity. …”
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Reshaping the tumor microenvironment of cold soft-tissue sarcomas with anti-angiogenics: a phase 2 trial of regorafenib combined with avelumab by Maud Toulmonde, Jean-Philippe Guégan, Mariella Spalato-Ceruso, Thibaud Valentin, Rastilav Bahleda, Florent Peyraud, Christophe Rey, Michèle Kind, Coralie Cantarel, Carine Bellera, Lucile Vanhersecke, Alban Bessede, Antoine Italiano

“…Overall, these results indicate that anti-angiogenic therapy modulates the tumor microenvironment in patients with cold STS and highlight the need for complementary strategies to enhance the functional activity of immune cells in this particular setting. …”
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Genetic parameters of growth and leaf traits and genetic gains with MGIDI in three Populus simonii × P. nigra families at two spacings by Tianxin Wang, Jingshan Ren, Qinjun Huang, Jinhua Li

“…., have great potential to significantly enhance genetic gain from selection. Growth and its functional and structural determinants exhibiting a high level of variability are not only controlled by genetics, but also affected by environment, as well as genotype and environment interaction (G×E). …”
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Efficacy of vericiguat in patients with chronic heart failure and reduced ejection fraction: a prospective observational study by Yinge Zhan, Liu Li, Jie Zhou, Yishan Ma, Xuchong Guan, Suo Wang, Ya Chang

“…Abstract Objectives This study aims to evaluate the therapeutic effect of Vericiguat through cardiopulmonary exercise testing (CPET) in patients with chronic heart failure and reduced ejection fraction (HFrEF). …”
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Cardiovascular risk and the possibility of its correction in women with premature ovarian insufficiency by A. A. Pozdnyakova, L. A. Marchenko, N. K. Runikhina

“…The HRT has anti-atherogenic, antiinflammatory, and angioprotective effects, regulates the production of endothelium-dependent factors of vasoconstriction and vasodilation, leading to a reduction in the relative risk of CVD in general.…”
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Donor Finger Morbidity in Cross-Finger Flap: A Systematic Review and Meta-Analysis by Sourabh Shankar Chakraborty, Ranjit Kumar Sahu, Sudeshna Acharya, Akhil Dhanesh Goel, Manojit Midya, Suresh Kotu

“…Background The morbidity of donor finger in a cross-finger flap has not received as much importance as the outcomes of the flap itself. The sensory, functional, and aesthetic morbidity of donor fingers, reported by various authors, are often contradictory to each other. …”
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How to Pick a Neuroprotective Drug in Stroke Without Losing Your Mind? by Joseph S. Tauskela, Nicolas Blondeau

“…This framework should include new technologies such as multi-electrode arrays (MEAs), which allow the evaluation of adverse effects of drugs alone, as well as if a drug truly provides functional neuroprotection, and not just survival. …”
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Machine-learning based optimizing the neutronic and thermal-hydraulic performance in a VVER-1000 mixed-core as well as fuel burnup assessment by A. Koraniany, G.R. Ansarifar

“…The reactor core of a functioning power plant usually contains hundreds of fuel assemblies. …”
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Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators. by Katalina Cruz, Antonio Marcilla, Patrick Kelly, Michel Vandenplas, Antonio Osuna, María Trelis

“…The accumulation of the long-term effects translates into poverty promoting sequelae and a cycle of impoverishment. …”
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Predictors of external branch of superior laryngeal nerve paresis and paralysis in patients undergoing thyroidectomy: by videostroboscopy by Manoj Kumar N., Rajiv S.R., T. M. Nagaraj, Sweta S., Ramya K., Pavitra N.

“…Abstract Background Thyroidectomy is one of the most commonly done surgery in otorhinolaryngology; hence, a pre-operative analysis of the recurrent laryngeal nerve and superior laryngeal nerve functions of laryngeal musculature is very important. …”
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The Comparison of the Profile of Phenolic Compounds in Noni (<i>Morinda citrifolia</i> L.) Fruit by Different Drying Methods by Qianxin Li, Juan Chai, Shenghui Deng, Jucai Xu, Yanxian Feng, Ruili Yang, Wu Li

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