Construction and Brain Validation of circRNAs-miRNAs-mRNAs Regulatory Axis in Early-Onset Schizophrenia by Zhang X, Li Z, Li R, Wang X, Liu H, Du X, Gao Y, Liu S, Xu Y

“…Hsa-circ-0000713 acted as a sponge, mitigating the inhibitory effects of hsa-miR-370-3p on ANK3 and MGLL. The expression patterns of this axis in the prefrontal cortex were consistent with those observed in peripheral blood samples from clinical patients.Conclusion: This study identified a specific multi-molecular axis in early-onset schizophrenia, wherein hsa-circ-0000713 functioned as a sponge to reduce the inhibitory effects of hsa-miR-370-3p on ANK3 and MGLL. …”
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Zuogui Pill Promotes Neurovascular Regeneration and Corticospinal Tract Remodeling After Ischemic Stroke by Wu D, Yan X, Mei S, Hua H, Fei X, Xu X, Liu Y, Wu M, Zhu J, Li W

“…Neurovascular regeneration and remodeling of the corticospinal tracts are essential for neurological functional recovery. Zuogui pill (ZGP) has good efficacy in treating cerebral ischemia, but the mechanism remains unclear.Purpose: To investigate the effects of ZGP on angiogenesis, neurogenesis, corticospinal tract (CST) remodeling, and further evaluate its mechanisms of action in mice with ischemic stroke.Methods: Network pharmacology was used to analyze the active components, related targets, and mechanisms of ZGP’s action in promoting neurovascular regeneration after ischemic stroke. …”
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Quantitative and structural features of the SMN1 and SMN2 genes in patients with spinal muscular atrophy 5q by A. I. Vlasenko, V. D. Nazarov, S. V. Lapin, A. V. Mazing, E. A. Surkova, T. V. Blinova, T. M. Alekseeva

“…The number of SMN2 gene copies correlates with the age of molecular diagnosis and indirectly predicts the age of SMA onset. The effect of the SMN1/SMN2 hybrid gene on the age of molecular diagnosis of SMA was comparable to the effect of the regular SMN2 gene.…”
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PATHOMORPHOLOGICAL DYNAMIC DUST CHANGES OF LUNG VESSELS IN KUZBASS MINERS WITH DIFFERENT WORK EXPERIENCE by Олег Иванович Бондарев, Арнольд Михайлович Сурков, Павел Алексеевич Азаров, Сергей Николаевич Филимонов

“…Although there is an opinion about the significant effect of products from the cytotoxic effect of silicate dust and industrial poisons on the endothelium with the development of perivascular sclerosis [1, 2]. …”
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Exploring the Ethical Challenges of Conversational AI in Mental Health Care: Scoping Review by Mehrdad Rahsepar Meadi, Tomas Sillekens, Suzanne Metselaar, Anton van Balkom, Justin Bernstein, Neeltje Batelaan

“…We included articles discussing the ethical challenges of CAI functioning in the role of a therapist for individuals with mental health issues. …”
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Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…However, its sustained effects on improving KOA symptoms were not observed.…”
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Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of in... by Steffen Bank, Paal Skytt Andersen, Johan Burisch, Natalia Pedersen, Stine Roug, Julie Galsgaard, Stine Ydegaard Turino, Jacob Broder Brodersen, Shaista Rashid, Britt Kaiser Rasmussen, Sara Avlund, Thomas Bastholm Olesen, Hans Jürgen Hoffmann, Marianne Kragh Thomsen, Vibeke Ostergaard Thomsen, Morten Frydenberg, Bjørn Andersen Nexø, Jacob Sode, Ulla Vogel, Vibeke Andersen, Vibeke Andersen

“…<h4>Background</h4>The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. …”
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Green Synthesis, Characterization and Pharmaceutical Applications of Biocompatible Zinc Oxide Nanoparticles Using <i>Heliotropium rariflorum</i> Stocks by Noor Ul Uza, Ghulam Dastagir, Syed Tanveer Shah, Elitsa Pavlova, Aftab Jamal, Mahmoud F. Seleiman, Jakub Černý

“…The nanoparticles exhibited a maximum antioxidant effect of 85.28% at 100 μg/mL. In this study, the acute toxicity test showed no mortality, and normal behavior was observed in mice at ZnO-NP doses of 5, 10, and 20 mg/kg. …”
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Protocol for an economic evaluation alongside a natural experiment to evaluate the impact of later trading hours for bars and clubs in the night-time economy in Scotland: The ELEPH... by Colin Angus, Emma McIntosh, Nurnabi Sheikh, Jim Lewsey, Niamh Fitzgerald, Carol Emslie, Houra Haghpanahan

“…A number of economic evaluation frameworks will be employed. A cost-effectiveness analysis (CEA) is appropriate for assessing the effectiveness of complex interventions when the impacts of policy are measured in natural units. …”
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A green forage diet enhances microbial diversity in buffalo rumen by Angela Salzano, Giovanna Bifulco, Alfio Calanni Macchio, Valentina Longobardi, Francesca Aragona, Giovan Maria Pacelli, Giuseppe Campanile

“…We conclude that including green forage in the diet can stimulate a more taxonomically and functionally diverse rumen microbiome with positive effects on microbiota total biodiversity, which might improve the health and productivity of the buffaloes. …”
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Ab Initio Investigation on the Magnetic Moments, Magnetocrystalline Anisotropy and Curie Temperature of Fe₂P-Based Magnets by Stephan Erdmann, Halil İbrahim Sözen, Thorsten Klüner

“…In this study, density functional theory was employed to investigate the effect of Si and Co substitution on the magnetic moments, magnetocrystalline anisotropy energy (MAE) and Curie temperature in <inline-formula><math display="inline"><semantics><msub><mi>Fe</mi><mrow><mn>2</mn><mo>−</mo><mi>y</mi></mrow></msub></semantics></math></inline-formula>Co_<i>y</i>P_1−<i>x</i>Si_<i>x</i> compounds. …”
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Seasonal ice storage changes and meltwater generation at Murtèl rock glacier (Engadine, eastern Swiss Alps): estimates from measurements and energy budgets in the coarse blocky act... by D. Amschwand, D. Amschwand, S. Tschan, M. Scherler, M. Hoelzle, B. Krummenacher, A. Haberkorn, C. Kienholz, L. Aschwanden, H. Gubler

“…In this case study, we assess the role and functioning of the intact Murtèl rock glacier in the hydrological cycle of its small (30 ha) periglacial and unglacierised watershed located in the Upper Engadine (eastern Swiss Alps). …”
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Construction and characterization of chimeric FcγR T cells for universal T cell therapy by Juanjuan Zhao, Manling Chen, Xudong Li, Zhaoqi Chen, Wei Li, Rongqun Guo, Min Wang, Zhongxing Jiang, Yongping Song, Jianxiang Wang, Delong Liu

“…Conclusion The anti-tumor effects of the CFR T cells in vitro and in xenograft mouse models are mediated by specific MoAbs such as RTX and herceptin. …”
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Fall risk perception toolkit based on “digital human” for community-dwelling older patients with stroke: development and validation by Jiang Nan, Yi Hou, Manyao Sun, Xueying Huang, Jing Gao, Xueqiong Zou, Zhongyi Chen, Yuyu Jiang

“…Abstract Background This study aims to develop a fall risk perception toolkit based on “digital human” (FRP-digital human), test its usability among community-dwelling older patients with stroke, and verify its implementation effect. Methods The toolkit underwent three phases: development, usability test, and effectiveness verification. …”
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Impact of sodium-glucose cotransporter-2 inhibitors on aging biomarkers and plasma ceramide levels in type 2 diabetes: beyond glycemic control by Youssef M. Shalaby, Mohammed Moutaz Nakhal, Bachar Afandi, Bashar Al-Zohily, Lina Majed, Kukkala Kiran Kumar, Bright Starling Emerald, Bassem Sadek, Amal Akour, Nadia Akawi

“…Background Aging is a complex biological process marked by the decline of physiological functions and heightened susceptibility to chronic illnesses, notably cardiometabolic disorders. …”
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PENGEMBANGAN LKPD FUNGSI KUADRAT BERBASIS PEMBUKTIAN DENGAN MODEL ARGUMENTASI TOULMIN UNTUK MEMFASILITASI KEMAMPUAN ARGUMEN MATEMATIS by Debi Suci Putri, Cecil Hiltrimartin, Yusuf Hartono, Nyimas Aisyah

“…The following research aims to obtain proof-based student worksheet on quadratic functions in high school that is valid and practical and has a potential effect on students' mathematical argumentation abilities. …”
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The aqueous extract of Artemisia Absinthium L. stimulates HO-1/MT-1/Cyp450 signaling pathway via oxidative stress regulation induced by aluminium oxide nanoparticles (α and γ) anim... by Esmaeil Karami, Zahra Goodarzi, Seyed Jamaleddin Shahtaheri, Mehrafarin Kiani, Mohammad Faridan, Mahmoud Ghazi-Khansari

“…Abstract Background This research aimed to evaluate the protective effects of Artemisia Absinthium L. (Abs) against liver damage induced by aluminium oxide nanoparticles (Al2O3 NPs) in rats, including both structural and functional changes associated with hepatotoxicity. …”
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Salvamento y socorrismo como deporte inclusivo: una aproximación a la opinión de personas con dis-capacidad intelectual (Lifesaving as an inclusive sport: an approach to the opinio... by María Teresa Calle-Molina, Ismael Sanz-Arribas

“…Keywords: Aquatic activities, Lifesaving, Functional diversity, Inclusive sport, Social justice. …”
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Dry needling as an adjunct treatment to multimodal rehabilitation protocol following rotator cuff repair surgery: a preliminary, randomized sham-controlled trial by Faeze Naseri, Mehdi Dadgoo, Mohammadreza Pourahmadi, Morteza Nakhaei Amroodi, Shirin Azizi, Amirhossein Shamsi

“…This study aimed to describe a preliminary, randomized, sham-controlled trial to evaluate the effectiveness of implementing 4 sessions of myofascial trigger point dry needling (MTrP-DN) as a muscle treatment approach along with 10 sessions of multimodal rehabilitation protocol (MRh) consisting of therapeutic exercise, manual therapy, and electrotherapy on postoperative shoulder pain, range of motion (ROM), strength, and functional outcome scores for patients following RCR surgery. …”
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Associations Between Obstructive Sleep Apnea and Metabolic Dysfunction-Associated Fatty Liver Disease: Insights from Comprehensive Mendelian Randomization and Gene Expression Analy... by Ma T, Liao C, Chen W, Feng J

“…Gene expression profiles were analyzed to identify intersection genes through differential expression analysis and weighted gene co-expression network analysis (WGCNA). Functional enrichment (GO and KEGG), protein–protein interaction (PPI) networks, and immune cell infiltration analyses (ssGSEA) were performed on the intersecting genes. …”
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