TRAF3IP3 Induces ER Stress‐Mediated Apoptosis with Protective Autophagy to Inhibit Lung Adenocarcinoma Proliferation by Guang Zhao, Jun Qi, Fang Li, Haotian Ma, Rui Wang, Xiuyi Yu, Yufei Wang, Sida Qin, Jie Wu, Chen Huang, Hong Ren, Boxiang Zhang

“…However, the specific effects and molecular mechanisms of TRAF3IP3 on the progression of lung adenocarcinoma (LUAD) remains poorly understood. …”
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Self-Reduction of Nitric Oxide on Alumina-Supported Ultra-Small Nickel Particles by Ramazan T. Magkoev, Yong Men, Reza Behjatmanesh-Ardakani, Mohammadreza Elahifard, Nelli E. Pukhaeva, Aleksandr A. Takaev, Ramazan A. Khekilaev, Tamerlan T. Magkoev, Oleg. G. Ashkhotov

“…The observed molecular conversion effects offer an opportunity to tune the catalytic selectivity of this and related metal/oxide systems via varying the supported metal particle size.…”
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Thermomorphic pneumatic metamaterials: numerous and robust shape-locking under temperature modulation through 4D printing by Yafei Wang, Wei Cai, Jingyi Zhang, Weijia Guo, Biyun Qi, Yuheng Liu, Weimin Huang, Haibao Lu, Xueyong Wei, Richard Fu, Zhen Ding

“…These shapes exhibit a remarkable temperature memory effect, permanently recording the peak temperature reached in their thermal history. …”
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Flexible self‐supporting organic cathode with interface engineering for high‐performance and wide‐temperature sodium‐ion batteries by Lei Wang, Suqiao Fang, Haichao Wang, Qianqian Peng, Yifeng Liu, Hanghang Dong, Hao Yan, Yong Wang, Shulei Chou, Bing Sun, Yao Xiao, Shuangqiang Chen

“…The sodium storage mechanism was verified to be a reversible oxidation reaction between two Na+ ions and carbonyl groups by density functional theory calculations, in situ infrared Fourier transform infrared spectroscopy, and in situ Raman spectroscopy. …”
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ADAMTS4 exacerbates lung cancer progression via regulating c-Myc protein stability and activating MAPK signaling pathway by Wei Zhai, Wensheng Yang, Jing Ge, Xuelian Xiao, Kang Wu, Kelin She, Yu Zhou, Yi Kong, Lin Wu, Shiya Luo, Xingxiang Pu

“…Methods ADAMTS4 expression was identified in human lung cancer samples by immunohistochemical (IHC) staining and the correlation of ADAMTS4 with clinical outcome was determined. The functional impact of ADAMTS4 on malignant phenotypes of lung cancer cells was explored both in vitro and in vivo. …”
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Hydrogels and Nanogels: Pioneering the Future of Advanced Drug Delivery Systems by Ernesto J. Delgado-Pujol, Guillermo Martínez, David Casado-Jurado, Juan Vázquez, Jesús León-Barberena, David Rodríguez-Lucena, Yadir Torres, Ana Alcudia, Belén Begines

“…Conventional drug delivery approaches, including tablets and capsules, often suffer from reduced therapeutic effectiveness, largely attributed to inadequate bioavailability and difficulties in ensuring patient adherence. …”
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Incorporation of amoxicillin-loaded microspheres in mineral trioxide aggregate cement: an in vitro study by Fábio Rocha Bohns, Vicente Castelo Branco Leitune, Isadora Martini Garcia, Bruna Genari, Nélio Bairros Dornelles, Silvia Stanisçuaski Guterres, Fabrício Aulo Ogliari, Mary Anne Sampaio de Melo, Fabrício Mezzomo Collares

“…The morphology of microspheres was observed under scanning electron microscopy.ResultsThe optimized cement formulation containing microspheres at 5% exhibited a delayed-release response and maintained its fundamental functional properties. When mixed with amoxicillin-loaded microspheres, the setting times of both test materials significantly increased. …”
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Flexible TiO₂/ZrO₂/AuCNAs Surface-Enhanced Raman Scattering Substrates for the Detection of Asomate in Apple Peel by Lina Zhao, Zhengdong Sun, Ye Shen, Zhiyang Chen, Yang Zhang, Jiyong Shi, Haroon Elrasheid Tahir, Xuechao Xu, Meng Zhang, Xiaobo Zou, Kaiyi Zheng

“…The density functional theory (DFT) simulation detailedly revealed that the SERS peaks could be generated by the interaction among asomate molecules, disassociated Au atoms, and Au facets. …”
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Changes of physicochemical, bioactive compounds and antioxidant activity of nutritional beverages products from VD20 broken Rice in the pasteurization process by Van Tan Pham, Thi Kim Loan Le, Duc Ngoc Vu, Thi Yen Nhi Tran, Long Giang Bach, Tan Phat Dao

“…VD20 broken rice, a byproduct of rice milling, shows significant potential for value-added applications, particularly in functional beverage production. This study investigates the impact of homogenization and pasteurization on the quality and stability of VD20 broken rice-based beverages. …”
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Here and there: the double-side transgene localization by P. A. Salnikov, A. A. Khabarova, G. S. Koksharova, R. V. Mungalov, P. S. Belokopytova, I. E. Pristyazhnuk, A. R. Nurislamov, P. Somatich, M. M. Gridina, V. S. Fishman

“…These techniques have already been used for functional gene annotation by transposon-insertion sequencing, for identification of transcription factor binding sites and regulatory sequences, and for dissecting chromatin position effects. …”
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Exploring Use of a Protein Cage System for Producing Bioactive Peptides in Escherichia coli by Maxim D. Harding, Mark A. Jackson, Edward K. Gilding, Kuok Yap, David J. Craik, Frank Sainsbury, Nicole Lawrence

“…Nevertheless, encapsulation in VLPs provided a useful first step in the purification pipeline for producing both linear and cyclic recombinant (r)BAPs that were functionally equivalent to their synthetic counterparts. …”
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Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis by Anne Lise Ferrara, Fabiana Piscitelli, Angelica Petraroli, Roberta Parente, Maria Rosaria Galdiero, Gilda Varricchi, Giancarlo Marone, Massimo Triggiani, Vincenzo Di Marzo, Stefania Loffredo

“…Our results may pave the way for investigating the functions of these mediators in the pathophysiology of mastocytosis and provide new potential biomarkers and therapeutic targets.…”
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The impact of a plant-based diet on the menstrual cycle and female fertility by Karina Ekiert, Katarzyna Pilarczyk, Aleksandra Rabęda, Natalia Klepacz, Zuzanna Cudziło, Hubert Sawczuk, Weronika Ewa Nowak, Marta Kaus, Hanna Adamska, Marta Malicka

“…Conclusions: A properly followed plant-based diet, supported by supplementation, has a positive effect on the female reproductive system, without causing menstrual cycle disorders or infertility. …”
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Crucian Carp-Derived ACE-Inhibitory Peptides with In Vivo Antihypertensive Activity: Insights into Bioactivity, Mechanism, and Safety by Runxi Han, Jingshan Tian, Yingge Han, Guoxiang Wang, Guanghong Zhou, Chen Dai, Chong Wang

“…These findings suggest that GA-Hyp-GAR is a promising natural ACE inhibitor with potential application in functional foods or as a nutraceutical for hypertension management.…”
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Ultramicroporous Ionic Liquid-Supported Aerogel Composites by Wenshuo Pan, Shaojuan Zeng, Jiang Chang, Guilin Li, Wei Zhang, Xiangping Zhang

“…These values significantly exceeded those of aerogels, owing to high hydroxyl ammonium ionic liquid (HAIL) loading, interactions between HAIL and NH₃, and ultramicropores, as confirmed by density functional theory (DFT) calculations and isothermal analysis. …”
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Dimensional control of interface coupling-induced ferromagnetism in CaRuO3/SrCuO2 superlattices by Li Zhe, Shi Wenxiao, Zhang Jine, Zheng Jie, Wang Mengqin, Zhu ZhaoZhao, Han Furong, Zhang Hui, Xie Liming, Yunzhong Chen, Fengxia Hu, Baogen Shen, Yuansha Chen, Jirong Sun

“…Understanding and controlling the coupling effects at the oxide interface are prerequisites for designing emergent interfacial phases with desired functionalities. …”
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Exploring fatty acids from royal jelly as a source of histone deacetylase inhibitors: from the hive to applications in human well-being and health by Fernanda Aparecida dos Santos France, Debora Kazumi Maeda, Ana Beatriz Rodrigues, Mai Ono, Franciele Lopes Nogueira Marchetti, Marcos Martins Marchetti, Allana Cristina Faustino Martins, Roberto da Silva Gomes, Cláudia Aparecida Rainho

“…Biochemical assays and gene expression analyses (Reverse Transcriptase – quantitative Polymerase Chain Reaction) were performed to evaluate the functional effects of the major RJ fatty acids, 10-HDA and 10-HDAA (10-hydroxy-decanoic acid), in two human cancer cell lines (HCT116 and MDA-MB-231). …”
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Heartbeat on hold: cortical processing of cardiac signals during motor preparation by Elena Mussini, Andrea Zaccaro, Mauro Gianni Perrucci, Marcello Costantini, Francesca Ferri

“…This modulation highlights a functional link between cardiac processing and motor inhibition, likely serving an adaptive role in optimizing physiological and cognitive readiness for scenarios requiring restraint and control.…”
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ROS-activated CD147-type I interferon signaling axis drives vascular smooth muscle cell fate transition and abdominal aortic aneurysm progression by Fangyuan Zhong, Hengyuan Zhang, Xinning Guo, Yichao Zhao, Yufei Wang, Wenli Li, Yuyan Lyu, Heng Ge, Xiyuan Lu, Jun Pu

“…Pharmacological inhibition of CD147 using Myricetin, a food-derived natural small-molecule compound, effectively discouraged oxidative stress-induced VSMC fate transition in vitro, and suppressed AAA progression and improved vascular integrity in two murine AAA models, underscoring its therapeutic potential. …”
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Advancements in deep learning for early diagnosis of Alzheimer’s disease using multimodal neuroimaging: challenges and future directions by Muhammad Liaquat Raza, Muhammad Liaquat Raza, Muhammad Liaquat Raza, Syed Tawassul Hassan, Subia Jamil, Noorulain Hyder, Kinza Batool, Sajidah Walji, Muhammad Khizar Abbas

“…We employed a best-evidence approach, prioritizing high-quality studies and identifying consistent patterns across the literature.ResultsDeep learning architectures, including convolutional neural networks, recurrent neural networks, and transformer-based models, have shown remarkable potential in analyzing multimodal neuroimaging data. These models can effectively process structural and functional imaging modalities, extracting relevant features and patterns associated with Alzheimer’s pathology. …”
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