Dual role of Eisenia fetida and its excreta in boosting tomato biomass and defense against Botrytis cinerea by Maryan Chelkha, Rubén Blanco-Pérez, Jorge Dueñas-Hernani, Ignacio Vicente-Díez, Victoria Pastor, Raquel Campos-Herrera

“…Soil organisms are key to plant growth and ecosystem functions. Earthworms (EWs) enhance soil and indirectly affect plant growth, while their cutaneous excreta (CEx) contain bioactive compounds capable of eliciting plant responses. …”
Get full text

Bacteria Derived from Diamondback Moth, <i>Plutella xylostella</i> (L.) (Lepidoptera: Plutellidae), Gut Regurgitant Negatively Regulate Glucose Oxidase-Mediated Anti-Defense Agains... by Qingxuan Qiao, Huiting Feng, Lu Jiao, Uroosa Zaheer, Chanqin Zheng, Li Zhou, Guifang Lin, Xiujuan Xiang, Huang Liao, Shanyu Li, Haiyan Lu, Anyuan Yin, Yussuf Mohamed Salum, Hui Wei, Wei Chen, Weiyi He, Feiying Yang

“…These RB strains suppressed genes related to jasmonic acid and glucosinolate signaling pathways but had little effect on salicylic acid signaling pathway genes in <i>Arabidopsis thaliana</i> wounds. …”
Get full text

Aurora kinase B inhibitor AZD1152: repurposing for treatment of lupus nephritis driven by the results of clinical trialsResearch in context by Yue Zhao, Zuguo Zheng, Xuexiao Jin, Shaoshan Liang, Changming Zhang, Mingchao Zhang, Yue Lang, Ping Li, Zhihong Liu

“…Transcriptome sequencing and functional assays were performed to elucidate its mechanisms of action. …”
Get full text

Multi-Objective Optimization Scheduling for Electric Vehicle Charging and Discharging: Peak-Load Shifting Strategy Based on Monte Carlo Sampling by Jian Zheng, Jinglan Cui, Zhongmei Zhao, Guocheng Li, Cong Wang, Zeguang Lu, Xiaohu Yang, Zhengguang Liu

“…For charge and discharge optimization, an EV charge and discharge scheduling model is constructed, aiming to balance multiple objective functions, including battery degradation costs, user charging costs, grid load fluctuations, and peak-to-valley differences. …”
Get full text

Integrative network pharmacology and experimental validation reveal emodin derivatives as potential therapeutics for hepatocellular carcinoma by Wirawan Adikusuma, Firdayani Firdayani, Siska Andrina Kusumastuti, Nuralih Nuralih, Shelvi Listiana, Ayu Masyita, Lalu Muhammad Irham, Siti Hodijah, Suci Zulaikha Hildayani, Eko Mugiyanto

“…Target predictions were performed using the SwissTargetPrediction database, and HCC-related genes were retrieved from cBioPortal. Functional annotations (Gene Ontology and Reactome) identified EGFR and KIT as key targets. …”
Get full text

Genomic characterisation of novel extremophile lineages from the thalassohaline lake Dziani Dzaha expands the metabolic repertoire of the PVC superphylum by Adrien Vigneron, Lilian A. Cloarec, Céline Brochier-Armanet, Jean Pierre Flandrois, Marc Troussellier, Cécile Bernard, Hélène Agogué, Philippe M. Oger, Mylène Hugoni

“…However, their evolutionary history and roles in ecosystem functioning and microbiome assemblage are poorly understood. …”
Get full text

Nano-erythrocyte membrane-chaperoned 5-fluorouracil liposomes as biomimetic delivery platforms to target hepatocellular carcinoma cell lines by Saeed A. AlQahtani, Gamaleldin I. Harisa, Mohamed M. Badran, Khalid M. AlGhamdi, Ashok Kumar, Mounir M. Salem-Bekhit, Sheikh F. Ahmad, Fars K. Alanazi

“…Nano-erythrocyte coating has been developed as an interesting biomimetic platform to provide hybrid nano-carriers with innate functions to target liver cancer. This goal was achieved by coating nano-erythrocyte membranes (NEMs) onto 5-fluorouracil (5-FU)-loaded liposomes (LPs) to produce NEM-5-FU-LPs. …”
Get full text

Co-Cultivation with Azolla Affects the Metabolome of Whole Rice Plant Beyond Canonical Inorganic Nitrogen Fertilization by Elena Consorti, Alma Costarelli, Sara Cannavò, Martina Cerri, Maria Cristina Valeri, Lara Reale, Antonietta Saccomanno, Chiara Paleni, Veronica Gregis, Martin M. Kater, Federico Brilli, Francesco Paolocci, Andrea Ghirardo

“…Overall, our study provides new insights into Azolla’s beneficial and growth-promoting effects on rice. Understanding the molecular mechanisms by which Azolla functions as a biostimulant in rice co-culture will facilitate the development of more sustainable and environmentally friendly techniques to increase yields.…”
Get full text

Spatiotemporal Dynamics of Ecosystem Service Value and Its Linkages with Landscape Pattern Changes in Xiong’an New Area, China (2014–2022) by Xinyang Ji, Dong Chen, Guangwei Li, Jingkai Guo, Jiafeng Liu, Jing Tong, Xiyong Sun, Xiaomin Du, Wenkai Zhang

“…As China’s third national-level new area, Xiong’an New Area plays a pivotal strategic role in relocating non-capital functions from Beijing while serving as a model for sustainable urban development. …”
Get full text

Degrees of Post‐Silking Water Deficit Alter the Structural, Pasting, and Gelatinization Properties of Waxy Maize Starch by Huan Yang, Longfei Wang, Jian Guo, Guanghao Li, Dalei Lu

“…Waxy maize starch is composed of nearly pure amylopectin, which endows with its high economic value. The effects of mild, moderate, and severe drought stresses during grain filling on the structural and functional properties of waxy maize starch were evaluated using two hybrids as materials. …”
Get full text

Cancer-associated fibroblasts-derived exosomal piR-35462 promotes the progression of oral squamous cell carcinoma via FTO/Twist1 pathway by Yushan Ye, Fan Wu, Bowen Li, Hanyu Ma, Lianxi Mai, Yu Peng, Xiaodi Feng, Xiao Tan, Min Fu, Yongmei Tan, Tianjun Lan, Ruixin Wang, Siqi Ren, Jinsong Li, Shaohai Chang, Shule Xie

“…Here, we explored the functional mechanism of exosomal piRNAs in OSCC development. …”
Get full text

The right temporoparietal junction during a cooperation dilemma: An rTMS study by Shisei Tei, Junya Fujino, Takashi Itahashi, Yuta Y. Aoki, Haruhisa Ohta, Manabu Kubota, Shuji Sawajiri, Ryu-ichiro Hashimoto, Hidehiko Takahashi, Nobumasa Kato, Motoaki Nakamura

“…Although published functional magnetic resonance imaging studies have shown the involvement of the right temporoparietal junction (TPJ) in resolving a dilemma through cooperation, a causal relationship between the two has rarely been explored. …”
Get full text

Impact of large herbivore rewilding on acorn dispersal dynamics by Mariana Rossa, Pedro Leite, Paloma Linck, Gabriel Moreira, Nanäa Mausberg, Joana Fernandes, Pedro Severino, João Duarte, Paula Maia, Rita Tinoco Torres, João Carvalho, Ramón Perea

“…Large herbivores drive ecosystem functions and processes through their direct or indirect impact on different habitats and wildlife communities. …”
Get full text

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapies by Kexin Luo, Kexin Luo, Kexin Luo, Kexin Luo, Meihan Liu, Meihan Liu, Meihan Liu, Meihan Liu, Zhongqin Peng, Zhongqin Peng, Zhongqin Peng, Haiyang Zhao, Haiyang Zhao, Haiyang Zhao, Haiyang Zhao, Guoyi Li, Guoyi Li, Guoyi Li, Guoyi Li, Yuanze Cai, Yumeng Lei, Hongpan Zhang, Hongpan Zhang, Yongsheng Zhao, Yongsheng Zhao

“…Immune cell infiltration and immune-related gene expression were evaluated in association with GNG7 levels. In vitro functional assays, including proliferation, migration, invasion, and apoptosis assays, were performed following GNG7 overexpression. …”
Get full text

Eugenol Nanoparticles in Dental Composites: Literature Review of Antimicrobial, Anti-Inflammatory, and Clinical Applications by Fatima Zahra Kamal, Alin Ciobica, Gabriel Dascalescu, Said Rammali, Mohamed El Aalaoui, Radu Lefter, Ioana Vata, Vasile Burlui, Bogdan Novac

“…It also exhibits anti-inflammatory effects that can promote healing by reducing post-operative sensitivity. …”
Get full text

Universal machine learning interatomic potentials poised to supplant DFT in modeling general defects in metals and random alloys by Fei Shuang, Zixiong Wei, Kai Liu, Wei Gao, Poulumi Dey

“…Recent advances in machine learning, combined with the generation of extensive density functional theory (DFT) datasets, have enabled the development of universal machine learning interatomic potentials (uMLIPs). …”
Get full text

Lipids in parenteral nutrition – expert consensus statements: Translating guidelines into clinical practice by Robert G. Martindale, Philip C. Calder, Sarah V. Cogle, David C. Evans, Leah Gramlich, Stephen A. McClave, Manpreet S. Mundi, Maurizio Muscaritoli, Reid Nishikawa, Jayshil Patel, Lorenzo Pradelli, Martin Rosenthal, Christian Stoppe, Kelly A. Tappenden, Malissa Warren, Dan Waitzberg, Paul E. Wischmeyer, Stanislaw Klek

“…In addition, lipids modulate a variety of biological functions, including inflammatory and immune responses. …”
Get full text

HY-Deepnet : A new Optimal Deep transfer learning empowered framework for an autonomous Alzheimer’s disease detection and diagnosis system by S. Veluchamy, R. Bhuvaneswari, K. Ashwini, Samah Alshathri, Walid El-Shafai

“…A progressive neurological disorder, Alzheimer’s disease (AD) predominantly impacts memory and cognitive functions of diseased victims. The disease is usually identified by the buildup of abnormal protein deposits in the brain, resulting in the development of plaques and tangles that interfere with communication between nerve cells. …”
Get full text

CD28 shapes T cell receptor signaling by regulating Lck dynamics and ZAP70 activation by Kumarkrishna Raychaudhuri, Kumarkrishna Raychaudhuri, Rohita Rangu, Alison Ma, Neriah Alvinez, Andy D. Tran, Sandeep Pallikkuth, Katherine M. McIntire, Joseph A. Garvey, Jason Yi, Lawrence E. Samelson

“…CD28 co-stimulation is also required to generate a functional immune response. Currently we lack a full understanding of the molecular mechanism of CD28 activation.MethodsWe employed TIRF microscopy to establish detailed spatial and kinetic relationships among these molecules in live Jurkat and murine primary T cells. …”
Get full text

ROS-balancing-engineered bio-heterojunction hydrogel accelerated the infected bone regeneration based on Sono-chemo dynamic therapy by Jiani Xu, Fanshangming Zhou, Lingyan Cao, Huilin Wang, Jiani Hu, Shuo Qiu, Yulan Liu, Yan Zhang, Jie Wang, Xinquan Jiang

“…Therefore, this work introduces a novel strategy for equipping hydrogels with programmed antibacterial and anti-inflammatory functionalities, providing an innovative solution for treating deep-seated infections, particularly in periodontitis therapy.…”
Get full text