Genome-Wide Identification and Characterization of SNPs and InDels of <i>Capsicum annuum</i> var. <i>glabriusculum</i> from Mexico Based on Whole Genome Sequencing by Valeria Itzel Moreno-Contreras, Ma. Carmen E. Delgado-Gardea, Jesús A. Ramos-Hernández, Alfonso Mendez-Tenorio, Hugo Varela-Rodríguez, Blanca Sánchez-Ramírez, Zilia Y. Muñoz-Ramírez, Rocío Infante-Ramírez

“…This study provides knowledge of the principal functions associated with high- and moderate-impact variants and supplies a resource for further investigations of the genetic characteristics of these chiltepin peppers.…”
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Cheby-KANs: Advanced Kolmogorov&#x2013;Arnold Networks for Applying Geometric Deep Learning in Quantum Chemistry Applications by Amgad Abdallah Mahmoud, Andreas Pester, Maha M. Muttardi, Frederic Andres, Shihori Tanabe, Nicolas Greneche, Hesham H. Ali

“…We integrated our algorithm with a geometric deep learning model (SchNet) to assess the effect of integrating KANs representation on geometric deep learning by combining domain knowledge of quantum chemistry and our new representation. …”
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Peptide Toxin Diversity and a Novel Antimicrobial Peptide from the Spider <i>Oxyopes forcipiformis</i> by Kexin Wang, James Mwangi, Kaixun Cao, Yi Wang, Jinai Gao, Min Yang, Brenda B. Michira, Qiumin Lu, Juan Li

“…Our findings provided a basis for targeted studies of the diversity and pharmacological effects of lynx spider peptide. We elucidated a valuable high-throughput approach for obtaining proteins and peptides from small-group spiders.…”
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Integrated approach of network pharmacology, molecular docking, and clinical observations in evaluating the efficacy and safety of Bufei Huoxue capsules for pulmonary hypertension... by Wenjun He, Chunli Liu, Xuanyi Li, Bihua Zhong, Qian Jiang, Ning Lai, Yuanhui Xiong, Weici Feng, Yilin Chen, Dansha Zhou, Defu Li, Wenju Lu, Jurjan Aman, Harm Jan Bogaard, Jian Wang, Yuqin Chen

“…BHCs exhibit therapeutic effects on COPD‐PH through multi‐component, multi‐target, and multi‐pathway interactions. …”
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Dual therapeutic potential of Scoparia dulcis in combating hyperglycemia and inflammation in diabetes through network pharmacology and in silico analysis by Ngoc-Thac Pham, Huong-Giang Le, Thuy-Tien Thi Phan, Phuong Vu Luu, Bo-Rong Peng, Lo-Yun Chen, Yu-Chia Chang, Kuei-Hung Lai

“…Existing literature supports the antidiabetic effects of these bioactive compounds, reinforcing the in silico findings. …”
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Enhancing T cell anti-tumor efficacy with a PD1-TIGIT chimeric immune-checkpoint switch receptor by Jingjing Zhao, Jiebin Dong, Changwen Deng, Qianjing Zhang, Shicheng Sun, Honggang Li, Yun Bai, Hongkui Deng

“…In addition to neutralizing PDL1 and CD155, this chimeric receptor is engineered with the transmembrane region and intracellular domain of CD28, thereby effectively enhancing T cell survival and tumor-targeting functions. …”
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Impact of in-hospital COVID-19 quarantine policy changes on quality of acute stroke care: a single center experience by Minkyung Kim, Keon-Joo Lee, Seong-Eun Kim, Hokyu Kim, Jung Hoon Han, Han Jun Kim, Kyungmi Oh, Sung-Jun Park, Chi Kyung Kim, Young-Duck Cho

“…The purpose of this study was to determine effects of changes in in-hospital quarantine policies on quality of care for acute stroke patients.MethodsHyperacute ischemic stroke patients who were admitted to Korea University Guro Hospital between January 2019 and February 2021 via the emergency department were included in this study. …”
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Thermal analysis and multi-objective optimization of equal-area microfluidic cooling systems by Yucheng Wang, Antong Bi, Yue Yao, Weiting Chen, Kaiyu Chen, Shenxin Yu, Jiangang Yu, Chao Wang, Wei Li, Shaoxi Wang

“…This study investigates the effects of different microchannel geometries on cooling performance while maintaining a constant heat transfer area. …”
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MicroRNA-767-5p promotes metastasis but improves chemotherapeutic and radiotherapeutic sensitivity of osteosarcoma by Xuelian Luo, Xiaoyan Dai, Qingsong Wei, Xiaorong Tan, Shuai Wang, Hanxi Xiao, Xuan Yao, Youcai Deng, Zhaoyang Zhong

“…We observed that miR-767-5p expression in the specimens of patients with metastatic OS was higher than in healthy individuals and was also negatively correlated with the overall survival of patients with OS. Functional assays (CCK-8, transwell, colony formation) and a tumor xenograft model demonstrated that miR-767-5p over-expression in both U2OS and 143B OS cell lines promoted cell invasion and migration without affecting proliferation, whereas its knockdown had opposite effects. …”
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On the determination of the interaction time of GeV neutrinos in large argon gas TPCs by A. Saá-Hernández, D. González-Díaz, J. Martín-Albo, M. Tuzi, P. Amedo, J. Baldonedo, C. Benítez, S. Bounasser, E. Casarejos, J. Collazo, A. Fernández-Prieto, D. J. Fernández-Posada, R. Hafeji, S. Leardini, D. Rodas-Rodríguez, A. L. Saborido, A. Segade, A. Slater

“…We propose to accomplish this through an optically-read time projection chamber (TPC) filled with high-pressure argon and equipped with both tracking and timing functions. In this work, we present a detailed study of the time-tagging capabilities of such a device, based on end-to-end optical simulations that include the effect of photon propagation, photosensor response, dark count rate and pulse reconstruction. …”
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Sleep in the elderly: Healthy sleep for healthy aging by Hrnčić Dragan, Šutulović Nikola, Mladenović Dušan, Vesković Milena, Đurić Emilija, Rašić-Marković Aleksandra, Stanojlović Olivera

“…Moreover, healthy sleep is essential for cognitive functions and prevention of cognitive decline and memory impairments in the elderly. …”
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Application of Eco-Feed Produced by Aurantiochytrium sp. L3W Using Solid Food Waste for Producing Hirodai-dori Products Containing Omega-3 Fatty Acids by Brilian Pamungkas, Wataru Asao, Satoshi Nakai, Takahiro Nii, Wataru Nishijima, Takehiko Gotoh, Toshikazu Suenaga, Nurlaili Humaidah, Masaoki Tsudzuki

“…These findings have demonstrated that a biomass mixture containing Aurantiochytrium sp. strain L3W could be used as a functional eco-feed to increase and maintain the content of n-3FAs in chicken meat.…”
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Exploring the Spatial Variation in the Microbiota and Bile Acid Metabolism of the Compound Stomach in Intensively Farmed Yaks by Shichun He, Zaimei Yuan, Sifan Dai, Zibei Wang, Shusheng Zhao, Bin Zhang, Huaming Mao, Dongwang Wu

“…The results of this study provide new insights into the microbiota and bile acid metabolism functions in the rumen, reticulum, omasum, and abomasum of yaks. …”
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Synthesis of carbon fiber reinforced SiC aerogel composites with enhanced mechanical and antioxidant properties for high temperature insulation by Chunxue Zheng, Jie Yu, Xinyang Li, Jingbo Duan, Zhulin Huang, Ming Li, Xiaoye Hu, Yue Li

“…However, it is still challenging to achieve large-scale preparation of aerogels that integrate the above functions through a simple method. In this work, carbon fiber (CF) felts are introduced as a reinforcement and template to prepare silicon carbide nanowire (SiCnw) aerogel composites through a simple in-situ growth strategy. …”
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Corrosion inhibition properties of polyepoxysuccinic acid derivatives in acid media by LIU Huiyuan, LIU Xinhua, GUAN Junxia, WANG Ying, SHU Shili, WANG Lei, LI Yulong, YAN Zixuan, XIA Yubo, DU Jiarui, ZHOU Xin, XIANG Heqiong, ZHANG Xinyuan

“…The results showed that PESA-Lcy-Sea had the structural functional groups of PESA, L-cysteine and taurine, which was successfully synthesized and had good thermal stability. …”
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Feeding the Mind: The Role of Fermented Foods and Probiotics in Anxiety Treatment by Marta Ignatiuk-Chilkiewicz, Joanna Kałuska, Dominika Hakało, Adam Rafałowicz, Aleksandra Sokół, Klaudia Mościszko, Katarzyna Nowicka, Wiktor Klimek, Maria Majewska, Monika Olszanska

“…Recent research has increasingly focused on the gut-brain axis, because scientists have discovered that gut microbiota functions as a key controller of mental health. Scientists investigate fermented foods as dietary interventions because they contain probiotics and bioactive molecules to potentially adjust the gut-brain axis for anxiety symptom reduction. …”
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CDK2 inhibition sensitizes anthracycline-induced immunogenic cell death and enhances the efficacy of anti-PD-1 therapy by Yu Chen, Wancheng Liu, Qiaomei Cai, Chaohu Pan, Zhenghao Yin, Yijiao Tang, Zhixu He, Genhong Cheng, Liping Shu, Liping Shu

“…IntroductionCDK2 (Cyclin-dependent kinase 2) is an oncogenic cyclin-dependent kinase with potent mitogenic and immunosuppressive functions. Despite extensive research on CDK2 inhibitors, the lack of selectivity has made it unclear whether CDK2 inhibition specifically facilitate immunogenic cell death.MethodsWe used CRISPR-Cas9 system to generate Cdk2-/- MCA205 cells. …”
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Adjusting for seasonal harvest bias in the lactation index for white‐tailed deer management by Kamen L. Campbell, Bronson K. Strickland, Stephen Demarais, Phillip D. Jones, Guiming Wang, Chad M. Dacus, Christopher Cook, W. Matt Knox

“…For each population, we calculated distance of mean female harvest date from median parturition date, and included linear, quadratic, and cubic functions of mean harvest day as potential explanatory variables. …”
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Performance Enhancement of Methane Detection Using a Novel Self-Adaptive Mid-Infrared Absorption Spectroscopy Technique by Fang Song, Chuantao Zheng, Wanhong Yan, Wei Lin Ye, Yu Zhang, Yiding Wang, Frank K. Tittel

“…High- and low-frequency noise levels have the same functional variation trend on Allan deviation, which differs from white Gaussian noise. …”
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A ceRNA network mediated by LINC00475 in papillary thyroid carcinoma by Yang Yarong, Hua Wenjuan, Zeng Mei, Yu Liling, Zhang Baijun, Wen Liming

“…This study aimed to find out the functions and mechanism of lncRNA LINC00475 in PTC. …”
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