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70721
Pseudomonas rossensis sp. nov., a novel psychrotolerant species produces antimicrobial agents targeting resistant clinical isolates of Pseudomonas aeruginosa
Published 2025-01-01“…Genome mining further revealed several biosynthetic gene clusters, some of which are associated with antimicrobial activity. Functional assays supported the antimicrobial capabilities of this novel species, showing antagonistic effects against clinical isolates of Pseudomonas aeruginosa, possibly mediated by tailocins (phage tail-like particles).This comprehensive polyphasic study characterized a new cold-adapted species, for which we propose the name Pseudomonas rossensis sp. nov.…”
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70722
Ethyl acetate extract of Ruta graveolens: a specific and potent inhibitor against the drug-resistant EGFR_T790M mutant in NSCLC
Published 2025-04-01“…To this end, we evaluated the functional and therapeutic potential of a panel of polar and non-polar solvent extracts using various in vitro assay systems. …”
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70723
Urban digital twins for citizen-centric planning: A systematic review of built environment perception and public participation
Published 2025-09-01“…UDT studies primarily focus on visual and functional perception, with limited attention to auditory and risk perception dimensions. …”
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70724
ER membrane receptor FgGET2 plays critical roles in hyphal growth, asexual development, stress responses, and pathogenicity of Fusarium graminearum
Published 2025-04-01“…Deleting FgGET2 in F. graminearum had detrimental effects on vegetative growth polarity, vacuolar morphology, and conidial production, morphology, and germination. …”
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70725
Multi-omics and AI-driven advances in miRNA-mediated hair follicle regulation in cashmere goats
Published 2025-07-01“…Key miRNAs, including miR-31, miR-22, and miR-214, are explored for their effects on follicle growth, hair shaft formation, and pigment regulation. …”
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70726
Long-term inhibition of Hepatitis B virus gene expression by a primary microrna expressing ancestral adeno-associated viral vector
Published 2025-02-01“…Single dose administration of the vectors to cultured cells and HBV transgenic mice effected reductions of secreted HBV surface antigen (HBsAg). …”
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70727
A comprehensive review on the selection of plant's part as coagulant for water/wastewater treatment
Published 2025-09-01“…This review article explores the potential of each plant’s part functioning as a biocoagulant for pollutant removal. …”
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70728
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma
Published 2025-07-01“…SLC27A5 exhibits noncanonical functions beyond its metabolic role; however, its specific mechanisms in hepatocarcinogenesis remain elusive and are therefore investigated in this study. …”
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70729
In Vitro Antioxidant, Antithrombotic and Anti-Inflammatory Activities of Bioactive Metabolites Extracted from Kiwi and Its By-Products
Published 2025-06-01“…<b>Background/Objectives:</b> Growing interest in natural, health-promoting ingredients for functional foods, nutraceuticals, and cosmetics has increased the demand for bioactive compounds from kiwi (Actinidia deliciosa). …”
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70730
The Relationship Between Physical Activity and Migraines: Research on Prevention and Supportive Treatment
Published 2025-02-01“…Migraine significantly impacts the daily functioning of individuals affected by the condition. …”
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70731
Modeling Hot, Anisotropic Ion Beams in the Solar Wind Motivated by the Parker Solar Probe Observations near Perihelia
Published 2025-01-01“…These unstable velocity distribution functions (VDFs) are associated with enhanced, right-hand (RH) and left-hand (LH) polarized ion-scale kinetic wave activity, detected by the FIELDS instrument. …”
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70732
Integrating weighted gene co-expression network analysis and machine learning to elucidate neural characteristics in a mouse model of depression
Published 2025-06-01“…Genes including Oprm1 and BDNF demonstrated functional relevance in modulating neural activity and behavior, offering promising candidates for early diagnosis and individualized treatment of depression.…”
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70733
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease
Published 2025-06-01“…It also significantly reduced the abundances of Faecalibaculum rodentium while increasing Muribaculum intestinale, with its functional role being relevant to lipid metabolism regulation. …”
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70734
Using Baited Remote Underwater Video Surveys (BRUVs) to Analyze the Structure of Predators in Guanahacabibes National Park, Cuba
Published 2025-04-01“…The analyzed metrics validate the effectiveness of the management of the protected area and suggest the presence of healthy and resilient mesopredator fish communities.…”
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70735
Monosaccharide coating modulate the intracellular trafficking of gold nanoparticles in dendritic cellsKey findings
Published 2024-12-01“…Gold nanoparticles (AuNPs) have garnered interest as a platform for targeted drug delivery due to their biocompatibility, low toxicity and precise control over size, morphology and surface functionalization. Our investigation aimed to elucidate the intracellular uptake and trafficking of AuNPs coated with different combinations of monosaccharides (mannose, galactose, and fucose) in DCs. …”
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70736
Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer
Published 2025-08-01“…These effects could be transferred via CATED‐overexpressing sEVs from donor cells and HGSOC tumor sEVs. …”
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70737
Reversible Cortical Visual Impairment in an Adolescent Due to a Posterior Fossa Arachnoid Cyst: A Case Report
Published 2025-07-01“…<b>Background</b>: Arachnoid cysts are typically benign and asymptomatic, but large cysts can exert a mass effect on adjacent neural structures. Based on the available literature, no cases of cortical visual impairment (CVI) in an adolescent caused by posterior fossa arachnoid cysts have been reported. …”
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70738
Zr-MOF/MXene composite for enhanced photothermal catalytic CO2 reduction in atmospheric and industrial flue gas streams
Published 2024-12-01“…Density Functional Theory (DFT) calculations validate these findings. …”
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70739
Evaluating multimodal physiological signals for fear detection: relative utility of pupillometry, heart rate, and EEG
Published 2025-07-01“…Monitoring fear states is crucial for timely intervention and improved mental well-being. Although functional magnetic resonance imaging (fMRI) has provided valuable insights into the neural networks associated with fear, its high cost and environmental constraints limit its practical application in daily life. …”
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70740
Integrative GWAS and transcriptomics reveal GhAMT2 as a key regulator of cotton resistance to Verticillium wilt
Published 2025-04-01“…Weighted Gene Co-expression Network Analysis (WGCNA) further linked GhAMT2 to critical defense pathways, including lignin biosynthesis, salicylic acid signaling, and reactive oxygen species (ROS) homeostasis, suggesting its role in cell wall reinforcement and systemic immune responses. Functional validation through virus-induced gene silencing (VIGS) confirmed that silencing GhAMT2 compromised disease resistance. …”
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