Standardizing Survey Data Collection to Enhance Reproducibility: Development and Comparative Evaluation of the ReproSchema Ecosystem by Yibei Chen, Dorota Jarecka, Sanu Ann Abraham, Remi Gau, Evan Ng, Daniel M Low, Isaac Bevers, Alistair Johnson, Anisha Keshavan, Arno Klein, Jon Clucas, Zaliqa Rosli, Steven M Hodge, Janosch Linkersdörfer, Hauke Bartsch, Samir Das, Damien Fair, David Kennedy, Satrajit S Ghosh

“…Our comparison results showed that ReproSchema met 14 of 14 FAIR criteria and supported 6 of 8 key survey functionalities: provision of standardized assessments, multilingual support, multimedia integration, data validation, advanced branching logic, and automated scoring. …”
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Klebsiella pneumoniae under xylose pressure: the growth adaptation, antimicrobial susceptibility, global proteomics analysis and role of XylA and XylB proteins by Ruolan Yi, Jiaoyang Zheng, Zhichao Xu, Jiayan Wu, Fangfang Liu, Jinxin Zheng, Duoyun Li, Shiqing Han, Zhijian Yu

“…Abstract Klebsiella pneumoniae can be cultured in medium with xylose as the sole carbon source. However, the effect of xylose exposure on its growth adaptation, virulence, antimicrobial susceptibility, and proteomic response remain unclear. …”
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SHP2 inhibition and adjuvant therapy synergistically target KIT‐mutant GISTs via ERK1/2‐regulated GSK3β/cyclin D1 pathway by Chunxiao He, Jiaying Yu, Shuang Mao, Shaohua Yang, Xianming Jiang, Lei Huang, Mingzhe Li, Yulong He, Xinhua Zhang, Xi Xiang

“…Rescue experiments confirmed that cyclin D1 is functional and critical for cell proliferation. Additionally, SHP2 inhibition synergised with approved KIT TKIs in inhibiting GIST cells. …”
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Non-invasive device to alleviate symptoms in people living with Parkinson’s: study protocol for a multicentre phase II double-blind randomised controlled trial by David Gallagher, Cristina Simonet, Alexandra Zirra, Alastair Noyce, Caroline Budu, Ellen Camboe, Viktoria Azoidou, Essa Bhadra, Kira Rowsell, Kamalesh Dey, Corrine Quah, Thomas Boyle

“…Measures include the recruitment, compliance and dropout rates, and safety/tolerability which will be collected through a participant clinical diary at baseline (week 0) and follow-up (week 13). Effectiveness will be evaluated at the same time points using movement tests (MDS-UPDRS Part III, Functional Gait Assessment, Timed Up and Go in isolation and with dual tasking and two keyboard-based typing tests—Bradykinesia Akinesia Incoordination and Digital Finger Tapping), with video recordings. …”
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Climate change and health through the lens of physical medicine and rehabilitation: A scoping review by Maya Newman, Kelli A. Kokame, Carl Froilan D. Leochico, Alexandra E. Fogarty, Jason Burton, Adam S. Tenforde, Marcalee Alexander

“…These conditions can cause physical disabilities, cognitive, sensory, or other functional impairments, which make these patients susceptible to the impacts of climate change. …”
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The ADAMTS2 metalloproteinase inhibits tumor growth by regulating the innate immune system by Loïc Joannes, Laura Dupont, Louis Stock, Esther Arpigny, Pascale Hubert, Marie Ancion, Margaux Luyckx, Joan Abinet, Wen Peng, Didier Calaldo, Agnes Noel, Thomas Marichal, Michael Herfs, Christophe Deroanne, Alain Colige

“…These data identify ADAMTS2 as a cancer regulator with antagonistic functions, limiting initial progression but promoting efficient metastatic dissemination.…”
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Exploring physiological and molecular dynamics of drought stress responses in plants: challenges and future directions by Sajad Ali, Rakeeb Ahmad Mir, Md Azizul Haque, Danishuddin, Mohammed A. Almalki, Mohammad Alfredan, Ashraf Khalifa, Henda Mahmoudi, Mohammad Shahid, Anshika Tyagi, Zahoor Ahmad Mir

“…In this review we first discuss the effect of drought stress on plants, soil physicochemical properties and microbiomes. …”
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RPL35A Downregulation Suppresses Hepatocellular Carcinoma Cell Proliferation via NCAPG2 Inactivation by Liang Chen, Yujie Lin, Yu Lai, Yanshan Li, Tao Chen, Xingxi Luo, Yibiao Ye

“…In vitro, we manipulated RPL35A expression in HCC cells using shRNA lentiviral vectors and assessed its effects on cell proliferation, migration and apoptosis. …”
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Bioactive Secondary Metabolites of Two Chinese Edible Boletes, <i>Phlebopus portentosus</i> and <i>Butyriboletus roseoflavus</i> by Zhixuan Wang, Wei Zhou, Yuhang He, Zeyu Zhao, Yang Cao, Shunzhen Luo, Guangyan Ji, Kaiping Ji, Jing Chen, Jiyang Li, Juan Xiong

“…Along with these, compound <b>29</b> showed a moderate antiviral effect against coxsackievirus B3. These findings underscore the therapeutic potential of the two edible boletes in addressing neurodegenerative diseases, cancer, and viral infections, paving the way for their prospective applications in the development of functional foods and pharmaceuticals.…”
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Gelatin from red tilapia (Oreochromis spp.) scales: Optimization of its extraction and detailed characterization of its chemical and viscoelastic properties by Jairo Andrés Camaño Echavarría, Amine Nekkaa, Philippe Arnoux, Christelle Mathé, Céline Cakir-Kiefer, Loïc Stefan, Cédric Paris, Katalin Selmeczi, José Edgar Zapata Montoya, Laetitia Canabady-Rochelle

“…Gelatin is widely used in food and pharmaceutical industries for its functional and bioactive properties. When extracted from fish by-products, the environmental impacts of these former waste are reduced. …”
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Chicken meat hydrolysate improves acetaminophen-induced liver injury by alleviating oxidative stress via modulation in Keap1/Nrf2/HO-1 signaling in BALB/c mice by Vipul Wayal, Zhuo-En Tsai, Yu-Hsuan Lin, Yi-Hsuan Lai, Shulhn-Der Wang, Chang-Chi Hsieh

“…Collectively, our results highlight the hepatoprotective effects of CMH against APAP-induced liver injury, supporting its potential as a functional food ingredient for liver health and mitigating APAP-induced acute liver injury.…”
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Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study by Can Qian, Ting Yuan, Fuyong Zhang, Shiyuan Gou, Chunmei Jiang, Xuebing Chen, Ya Huang, Xiaolin Zhao, You Du, Chenglong Li, Yangyun Han, Huaiyu Su

“…However, to further validate its effectiveness in reversing bacterial resistance, the program requires longer-term operation and could be considered for regional expansion.…”
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Protocol for a randomized controlled trial of transdermal continuous oxygen therapy for surgical site wound healing after lower extremity revascularization by Khanjan Nagarsheth, MD, Georges Jreij, MD, Eleanor Dunlap, DNP, Shannon Hawkins, DNP, Rachel White, BSN, Areck Ucuzian, MD, PhD, Brajesh K. Lal, MD

“…Following lower extremity revascularization, 40% to 50% of patients experience non-healing wounds that persist for months despite functional bypass grafts. Additionally, surgical site infections (SSIs) in these patients can lead to sepsis, disability, and limb loss. …”
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Use of quantitative CT chest imaging to derive and assess a radiographic phenotype of deployment-related constrictive bronchiolitis by Alexander J. Bell, Maria Masotti, Sundaresh Ram, Gregory Pappas, Robert F. Miller, Ella A. Kazerooni, Charles R. Hatt, MeiLan K. Han, Bradley W. Richmond, Michael J. Falvo, Craig J. Galban, John J. Osterholzer

“…Results Individual unadjusted QCT metrics for functional small airways disease and high attenuation area were elevated in DRCB and FDSV cohorts (relative to Control). …”
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Exploring the Anti-PANoptosis Mechanism of Dachaihu Decoction Against Sepsis-Induced Acute Lung Injury: Network Pharmacology, Bioinformatics, and Experimental Validation by Yang Z, Kao X, Zhang L, Huang N, Chen J, He M

“…Then, protein-protein interaction (PPI) network, molecular docking, and functional enrichment analysis were conducted. In vivo, cecal ligation and puncture (CLP) was used to construct a sepsis mouse model, and the therapeutic effects of DCHD on SALI were evaluated using hematoxylin and eosin (H&E) staining, quantitative real-time PCR (qRT-PCR), and ELISA. …”
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Stress Hyperglycemia Is Associated with Unfavorable Outcomes After Mechanical Thrombectomy in Patients with Acute Ischemic Stroke by Jie Gao, Xiangliang Chen, Qing Huang, Mengmeng Gu, Ye Hong, Gelin Xu

“…This study aimed to evaluate the effects of stress hyperglycemia on in-hospital and 3-month outcomes in stroke patients with anterior circulation occlusion undergoing mechanical thrombectomy. …”
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Influence of load-bearing wall material properties on building mine-induced dynamic response by Maciej Zajac, Krystyna Kuzniar, Tadeusz Tatara

“…The main goal of this article is to analyse the effect of load-bearing wall materials on a building’s dynamic response to mine-induced vibrations. …”
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Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis by Ann-Kathrin Daum, Lisa Schlicker, Marc A. Schneider, Thomas Muley, Ursula Klingmüller, Almut Schulze, Michael Thomas, Petros Christopoulos, Holger Sültmann

“…Single-cell RNA sequencing was performed to uncover transcriptional differences between TKI-treated homotypic and heterotypic spheroids. Functional assays assessed the effects of CAF-conditioned medium and CAF-secreted factors on tumor cell survival, proliferation, lipid metabolism, and downstream AKT signaling. …”
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Influence of drought stress on phosphorus dynamics and maize growth in tropical ecosystems by Mohsin Mahmood, Junjie Wang, Sajid Mehmood, Waqas Ahmed, Anam Ayyoub, Mahmoud F. Seleiman, Ahmed Salah Elrys, Ahmed S. M. Elnahal, Adnan Mustafa, Xiuwen Wei, Weidong Li

“…Abstract Drought has a significant impact on ecosystem functions, especially on the biogeochemical cycling of phosphorus (P), which is a crucial nutrient for plant growth and productivity. …”
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