Novel immunotargets in multiple myeloma: biological relevance and therapeutic potential by Jana Kotulová, Klára Baďurová, Zuzana Chyra, Sabina Ševčíková, Nikola Garbová, Tomáš Jelínek, Roman Hájek, Matouš Hrdinka

“…This review provides an overview of emerging immunotargets, summarizing their biological functions, roles in disease pathogenesis and immune evasion, and potential for therapeutic interventions. …”
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Unveiling the potential of a tri-seed synthesis approach: synthesis of zinc nanoparticles with enhanced antimicrobial properties by Aliyu Shehu, Oluwole Okunola Joshua, Uduma A. Uduma

“…FTIR analysis revealed the presence of functional groups such as Zn–O, C–O, HOH, CO₂, and OH, associated with capping agents and surface modifications. …”
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STEP analysis of macro-environmental factors affecting medical and drug care for patients with chronic myeloid leukemia by A. V. Zhuravlev, O. I. Knysh

“…Providing medical and drug care to CML patients today is a vital and pressing problem in Russia and around the world. The effectiveness of pharmacotherapy directly depends on certain environmental factors, and each of them influences the functioning of a medical organization (MO) to varying degrees. …”
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From ultra-low friction to superlubricity state of black phosphorus: Enabled by the critical oxidation and load by Qiang Li, Fenghua Su, Yanjun Chen, Jianfang Sun

“…Abstract Based on the density functional theory (DFT), we investigate the friction properties of inevitable oxidized black phosphorus (o-BP). o-BP with the weaker interlayer adhesion exhibits their great potential as a solid lubricant. …”
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Symbiont Types of Scleractinian Corals in Java and Bali Waters, Indonesia by Diah Permata Wijayanti, Elis Indrayanti, Dwi Haryanti, Mila Amelia Nur Azizah, Ranjeet Bhagooli

“…Several effects of global warming, particularly coral bleaching, have threatened the symbiotic system of coral reefs. …”
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Coffee processing waste as a reinforcing material in the preparation of chitosan-based magnetic composite for the removal of chromium (VI) from aqueous solution by Shimelis Kebede Kassahun, Amen Getaye, Konstantina Tsigkou, Irini Angelidaki

“…The composite adsorbent was synthesized using a co-precipitation method with different mixing ratios of chitosan to coffee husk fibers (27:75, 50:25, and 75:25). The surface functional groups, surface morphology, specific surface area, and crystal structure were investigated using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) analysis, and X-ray diffraction (XRD). …”
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Multitask and Transfer Learning Approach for Joint Classification and Severity Estimation of Dysphonia by Dosti Aziz, Sztaho David

“…Additionally, we conducted binary ‘healthy vs. dysphonia’ and multiclass ‘healthy vs. organic and functional dysphonia’ classification using multitask learning, with the speaker’s sex as an auxiliary task. …”
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Revolutionizing Holy-Basil Cultivation With AI-Enabled Hydroponics System by G. Lakshmi Priya, Chanthini Baskar, Sanket Sandeep Deshmane, C. Adithya, Souranil Das

“…The system utilizes the functionality of Azure IoT Hub, Azure Container, and Azure DataBricks, where we employ a logistic regression model on sensor data to classify the upcoming seasonal parameters such as nutrient dispensation, water stream, and light for optimal plant growth. …”
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FLIP: A Novel Feedback Learning-Based Intelligent Plugin Towards Accuracy Enhancement of Chinese OCR by Xinyue Tao, Yueyue Han, Yakai Jin, Yunzhi Wu

“…The plugin operates through three core components as follows: UTF-8 encoding-based output parsing that converts OCR results into mathematical representations, error correction using information entropy and weighted similarity measures to identify and fix character-level errors, and adaptive feedback learning that optimizes parameters through user interactions. The approach functions entirely through mathematical calculations at the character encoding level, ensuring universal compatibility with existing OCR systems while effectively handling complex Chinese character similarities. …”
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A Lamin Family-Based Signature Predicts Prognosis and Immunotherapy Response in Hepatocellular Carcinoma by Yongyu Yang, Wang Xiao, Ruoqi Liu, Lei Gao, Junzhang Chen, Heping Kan

“…The expression features and prognostic value of LMNA, LMNB1, and LMNB2 were explored in the TCGA and GEO databases. The biological functions of LMNB1 and LMNB2 were validated by in vitro assays. …”
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The physical therapy efficacy index and chart: a stimulus for value-based healthcare using real-world data by Henri Kiers, Richard A.W. Felius, Martijn W. Heijmans, Arie C. Verburg

“…Second, a Physiotherapy-specific Efficacy Index (PE-Index) for musculoskeletal disorders was formulated based on pain and functional improvement, treatments, and episode duration. …”
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EFFICACY AND SAFETY OF BISOPROLOL IN YOUNG MEN WITH ARTERIAL HYPERTENSION AND OBESITY by A. G. Avtandilov, I. I. Esenova, S. L. Petrosov

“…Aim. To evaluate effect of bisoprolol on circadian blood pressure (BP) profile, autonomic cardiovascular regulation, lipid and carbohydrate metabolism in young patients with arterial hypertension (HT) and obesity. …”
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PTML models of self assembled ligand free nanoparticle catalysts for cross coupling reactions by Andrea Ruiz-Escudero, Zuriñe Serna-Burgos, Sonia Arrasate, Humberto González-Díaz

“…MLP (9:9-20-18-1:1) classification model showed high precision (97.0%) and recall (93.8%), effectively distinguishing high- and low-yielding reactions. …”
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Impact of losartan-supplemented extender on enhancing rooster sperm quality post-freezing and thawing by Fatemeh Vandvali, Hossein Daghigh Kia, Marziyeh Ebrahimi, Gholamali Moghaddam, Abouzar Najafi

“…However, the process of sperm freezing and thawing often leads to damage, affecting the functional and biological properties of sperm cells. …”
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Features of the Development Strategy Customer Relationship Management by I. M. Gurova

“…In the process of collecting and collating data used content analysis, comparative analysis, methods of induction and deduction, system approach. Functional, strategic and economic analysis, methods of formalization, forecasting and expert assessments are used to generalize information and solve assigned tasks. …”
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Educational and research utility of the registrar clinical encounters in training (ReCEnT) project: an exploration of mechanisms using the context, input, process and product (CIPP... by Parker Magin, Andrew Davey, Michael Tran, Susan Wearne

“…Background The Registrar Clinical Encounters in Training (ReCEnT) project is an Australian general practice vocational training programme with integrated and interdependent education and research functions. Trainees (registrars) contemporaneously document in-consultation clinical experience and actions.Objectives Using a realist lens, we elucidate the mechanisms underpinning project outcomes to answer questions around programme effectiveness, impacts, sustainability and the lessons and findings that are translatable to other primary care training programmes.Methods The context, input, process and product framework was used. …”
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Relationship between physical activity levels and body composition of candidates for bariatric surgery: a pilot study by Thaiana Marcelino Lima, Wlaldemir Roberto dos Santos, Fabiano Ferreira De Lima, Laila Barbosa Santana, Igor Henriques Fortunato, Rodrigo Montenegro Wanderley, Maria Luíza Salviano da Silva, Larissa Rayanna do Amaral Silveira, Matthew Stults-Kolehmainen, Aline de Freitas Brito

“…The candidates for bariatric surgery predominantly have Class II and III obesity, interfering with body composition (lean mass, % body fat, and BMD), and, consequently, exposing greater physical and functional fragility. Although sarcopenia and a sedentary lifestyle are presented in the literature as conditions that impact body composition, it was not possible to identify significant differences in the sample. …”
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A telomere-related signature for predicting prognosis and assessing immune microenvironment in osteosarcoma by Shihao Li, Lina Zhang, Haiyang Zhang

“…The telomere-related signature could effectively predict the prognosis of osteosarcoma patients. …”
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The role of senescence-related genes in major depressive disorder: insights from machine learning and single cell analysis by Kun Lian, Wei Yang, Jing Ye, Yilan Chen, Lei Zhang, Xiufeng Xu

“…Single-cell RNA sequencing was used to analyze MDD SRGs functions. Results The five hub SRGs: ALOX15B, TNFSF13, MARCH 15, UBTD1, and MAPK14 showed differential expression between MDD patients and controls. …”
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Comparison of Physicochemical Properties of All-E and Z-astaxanthin: Experimental and Quantum Chemistry Analysis by LIU Xiaojuan, ZHOU Lesong, CHEN Jialing, KE Liang, FENG Yujie, XIAO Jie, CAO Yong

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