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69901
Glutathione peroxidase 7 knockdown inhibits growth, invasion, and migration while enhancing oxidative stress and ferroptosis in osteosarcoma cells
Published 2025-08-01“…Background: Glutathione peroxidase 7 (GPX7) possesses antioxidant functions and plays a crucial role in regulating cancer progression. …”
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69902
Development of psychological and educational aspects of interaction between medical workers and patients
Published 2023-12-01“…At the second stage, the theoretical concept of the study was adjusted, a training experiment was conducted with doctors and senior nurses, and a structural and functional model of pedagogical training of medical workers for patient education was introduced. …”
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69903
Long-Term Outcomes in Crosslinking Therapy for Patients with Progressive Keratoconus
Published 2025-03-01“…<b>Conclusions:</b> CXL treatment is an important treatment method in the treatment of keratoconus, preserving visual functions, significantly reducing the severity of astigmatism, and stopping the progression of keratoconus. …”
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69904
Rapid activation of Rac GTPase in living cells by force is independent of Src.
Published 2009-11-01“…It is well known that mechanical forces are crucial in regulating functions of every tissue and organ in a human body. …”
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69905
Jump Control Based on Nonlinear Wheel-Spring-Loaded Inverted Pendulum Model: Validation of a Wheeled-Bipedal Robot with Single-Degree-of-Freedom Legs
Published 2025-04-01“…The jump height is increased by 3.4 times compared to the linear spring model. Then, cost functions are established based on this virtual model, and the trajectory for each stage is iteratively optimized using Quadratic Programming (QP) and a bisection method. …”
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69906
Integrated analysis of single-cell and bulk RNA sequencing to construct a CD8+ T cell-related immune gene signature in pancreatic cancer
Published 2025-03-01“…Our findings suggest that patients with low TIGs scores have stronger immune effector functions and immune checkpoint activation, resulting in a more favorable response to PD-L1 inhibitors. …”
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69907
Genetic evidence for amlodipine's protective role in gastroesophageal reflux disease: A focus on CACNB2.
Published 2025-01-01“…<h4>Conclusion</h4>This study provides robust evidence of a protective effect of amlodipine against GERD, supported by genetic and molecular analyses. …”
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69908
Callus Induction of Gendarussa (Justicia gendarussa) by Various Concentration of 2,4-D, IBA, and BAP
Published 2017-12-01“…., a medicinal plant, is Acanthaceae that has many functions. Furthermore, the compounds in gendarussa must be produced in high quantity and quality by applying callus culture method. …”
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69909
Combined TGF-β3 and FGF-2 Stimulation Enhances Chondrogenic Potential of Ovine Bone Marrow-Derived MSCs
Published 2025-07-01“…Dual stimulation with TGF-β3 and FGF-2 significantly improves the chondrogenic differentiation of ovine BM-MSCs by enhancing both molecular and functional markers of cartilage formation.…”
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69910
Differential approach in selecting beta-adrenoblocker therapy for patients with chronic heart failure and anaemia
Published 2012-04-01“…Anaemia is known as an adverse prognostic factor in CHF. Aim. To study the effects of β -AB therapy on the anaemia clinical course among CHF patients. …”
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69911
Regulation of human Th9 cell differentiation by lipid modulators targeting PPAR-γ and acetyl-CoA-carboxylase 1
Published 2024-12-01“…We demonstrate reciprocal functions for these enzymes, as ACC1 inhibition substantially increased IL-9 production, whereas AMPK inhibition resulted in undetectable levels. …”
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69912
Multifeature Fusion for Enhanced Content-Based Image Retrieval Across Diverse Data Types
Published 2025-01-01“…These findings underscore the effectiveness of Hausdrauff distance in enhancing retrieval precision within the CBIR framework.…”
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69913
Self-regulation as a context of critical thinking in cyberpolice officers
Published 2021-09-01“…Cyberpolice officers show a greater focus on action, hoping for success in dealing with situations of strong external pressure, greater ability to maintain the optimal functioning of all parts of self-regulation in extreme conditions, overcome anxiety and remain focused in stressful situations. …”
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69914
Determination of the Toxic Dose of Experimental Lead Poisoning for Male Goats in Fallujah City, Iraq
Published 2021-12-01“…This study aimed to induce lead poisoning experimentally in male goats to determine the toxic dose and investigate it is effects on hematological parameters, and the functions of the liver and kidney. …”
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69915
Insights into the profile, professional setting, and needs of in-home physiotherapists in Switzerland: a national online survey
Published 2025-05-01“…Abstract Background The aging of the population and the increasing prevalence of chronic diseases result in a growing number of people living with functional disabilities. Swiss public health policy and population preferences lead to an increase in the number of people staying at home rather than in institutions in Switzerland. …”
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69916
Holistic model of the formation of requirements for freight cars on the example of the “Northern Latitudinal Railway” project
Published 2020-11-01“…The model also makes it possible to predict the effects of participants in the transportation process when using cars with given characteristics in specific transportation conditions. …”
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69917
Population Genomics Reveals Small‐Scale Metapopulation Structure of Two Strictly Aquatic Keystone Species in a Recently Restored Urban River System (Emscher, Germany)
Published 2025-04-01“…However, the success of such ecological restoration measures is not guaranteed, and for many of the functionally important but smaller organisms, improved connectivity is difficult to assess. …”
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69918
Overexpression of EMMPRIN isoform 2 is associated with head and neck cancer metastasis.
Published 2014-01-01“…Using quantitative real-time PCR, we found that EMMPRIN isoform 2 (EMMPRIN-2) was the only isoform that was overexpressed in both head and neck cancer tissues and cell lines and that it was associated with head and neck cancer metastasis. To determine the effects of EMMPRIN-2 on head and neck cancer progression, we transfected head and neck cancer cells with an EMMPRIN-2 expression vector and EMMPRIN-2 siRNA to exogenously modulate EMMPRIN-2 expression and examined the functional importance of EMMPRIN-2 in head and neck cancer invasion and metastasis. …”
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69919
Evaluation of an inpatient psychocardiological rehabilitation program in Austria: Psychosocial outcomes of a six-month cohort study.
Published 2025-01-01“…We conducted a repeated measures multivariate analysis of variance (MANOVA) with heart-focused anxiety (CAQ), global psychological distress (SCL-90®-S) and health-related quality of life (SF-12) as combined dependent variables. Time and social functioning (SAS-SR) on admission were included as explanatory variables. …”
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69920
Overcurrent Limitation and Enhanced Fault Current Utilization by Grid-Forming Inverter Using Hybrid Methods During Short Circuit Faults
Published 2025-01-01“…By integrating NLTVR or UNLTVR with reconstructed power references based on grid fault severity, the inverter operates near its maximum current limit during faults while preserving GFM functionality, ensuring smooth post-fault power recovery without exceeding reference values. …”
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