Cross-feeding-based rational design of a probiotic combination of Bacterides xylanisolvens and Clostridium butyricum therapy for metabolic diseases by Shanshan Qiao, Tao Wang, Jingzu Sun, Junjie Han, Huanqin Dai, Mengxuan Du, Lan Yang, Chun-Jun Guo, Chang Liu, Shuang-Jiang Liu, Hongwei Liu

“…Moreover, the two-strain combinations more effectively restored gut microbial functions by reducing disease-associated pathways and opportunistic pathogen abundance. …”
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Hsa_circ_0001756 drives gastric cancer glycolysis by increasing the expression and stability of PGK1 mRNA by Long Qian, Long Qian, Long Qian, Luman Wang, Hao Chen, Song Wang, Song Wang, Yinfen Hou, Li Xu, Li Xu, Yabin Xia, Yabin Xia, Maoqi Xu, Xiaoxu Huang, Xiaoxu Huang

“…However, the mechanism underlying the effects of hsa_circ_0001756 in gastric cancer (GC) remains unclear.MethodsIn this study, we detected the expression of hsa_circ_0001756 in GC tissues and cells using quantitative real-time polymerase chain reaction (qRT PCR). …”
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Efficient Electrochemical CO2 Reduction Using AgN3 Single‐Atom Sites Embedded in Free‐Standing Electrodes for Flow Cell Applications by M. Nur Hossain, Ali Malek, Zhangsen Chen, Lei Zhang, Shuhui Sun, Hanshuo Liu, Roberto Neagu, Jigang Zhou, Hui Yuan, Christopher S. Allen, Gianluigi Botton

“…The catalytic activity and stability of the free‐standing Ag SACs are evaluated at a current density of 100 mA cm−2, demonstrating prolonged electrolysis with consistent Faradaic efficiency for CO production. Density functional theory calculations revealed that the AgN3 active site significantly lowers the energy barriers for the CO2 absorption step compared to AgAg and AgNi sites, facilitating CO2 activation and contributing to enhanced catalytic activity and stability during CO2 reduction. …”
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The FGF13‐Caveolin‐1 Axis: A Key Player in the Pathogenesis of Doxorubicin‐ and D‐Galactose‐Induced Premature Cardiac Aging by Enzhao Shen, Yuecheng Wu, Weijian Ye, Sihang Li, Junjie Zhu, Meifan Jiang, Zhicheng Hu, Gaoyong Cao, Xiaojing Yi, Fan Li, Zhouhao Tang, Xiaokun Li, Kwang Youl Lee, Litai Jin, Xu Wang, Weitao Cong

“…Furthermore, Cav1 overexpression in murine hearts reversed the alleviatory effects of FGF13 deficiency on the Doxorubicin/D‐galactose‐induced myocardial aging phenotype and dysfunction. …”
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Impact of Vegetal Protein on the Physicochemical and Microstructural Properties of Microencapsulated Mexican Red Pitaya (<i>Stenocereus thurberi</i>) Juice by David Neder-Suárez, Carmen Oralia Meléndez-Pizarro, Esther Pérez-Carrillo, Jesús Alberto Vázquez-Rodríguez, María del Cielo Valdez-Cárdenas, Martha Graciela Ruiz-Gutiérrez, Carlos Abel Amaya-Guerra, Francisco Paraguay-Delgado, Armando Quintero-Ramos

“…The effects of different carrier agents—pea protein (PP), rice protein (RP), bean protein (BP), whey protein (WP), and maltodextrin (MT, as a control)—on pitaya juice encapsulation via spray drying were evaluated. …”
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Oxygen vacancy-engineered bimetallic nanozymes for disrupting electron transport chain and synergistic multi-enzyme activity to reverse oxaliplatin resistance in colorectal cancer by Dong Zhong, Xiaoxin Yang, Jinhui Yang, Zhisheng Luo, Zhichao Feng, Mengtian Ma, Yunjie Liao, Yongxiang Tang, Yu Wen, Jun Liu, Shuo Hu

“…It also inhibits the glutathione S-transferase P1 (GSTP1) pathway, weakening tumor detoxification and enhancing chemotherapy sensitivity. Density functional theory calculations revealed that the synergistic effect among multi-enzyme active centers endows the CuMnOx−V nanozymes with excellent catalytic activity. …”
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Branched-Chain Amino Acids (BCAAs): Revisiting Their Role in Sport and Health by Aleksandra Kajtel, Anna Skowronek, Martyna Piekarska, Katarzyna Dąbek, Michał Ochwat, Maria Sudoł, Gabriela Mierzwa

“…Clinical studies demonstrate the potential benefits of BCAA supplementation, particularly when combined with resistance exercise, in improving muscle quality and functional outcomes. However, effects on broader physical performance markers, insulin sensitivity, and metabolic profiles remain inconsistent. …”
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Organ-on-chip platforms for nanoparticle toxicity and efficacy assessment: Advancing beyond traditional in vitro and in vivo models by Ana Regina Sampaio, Renata Faria Maia, Maria Camilla Ciardulli, Hélder A. Santos, Bruno Sarmento

“…Nanoparticles (NPs) have unique properties, such as their high surface-to-volume ratio, nanoscale size, and functionalization potential, make them promising for a variety of biomedical applications, including drug delivery, diagnostics, and targeted therapy. …”
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Spatiotemporal variations in habitat quality and their determinants in the Henan Section of the Yellow River Basin by ZHANG Yingying, MA Ziyan, YU Nan, WEI Dechao, CHEN Zhaojing, YUAN Shuting, WANG Zheng, SONG Xinxin, ZHAO Yongqiang

“…【Objective】The ecological functions of the Yellow River Basin have undergone significant changes in recent decades due to both natural and anthropogenic influences. …”
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Deficient of glycosylation site in the envelop protein attenuated Zika virus replication in mosquito cells by Wen-Jing Wang, Wen-Jing Wang, Zi-Han Wang, Zi-Han Wang, Jing Li, Jing Li, Sai-Ya Ma, Sai-Ya Ma, Mei He, Mei He, Meng-Xuan Liu, Meng-Xuan Liu, Yu-Fei Zhan, Yu-Fei Zhan, Feng Jin, Feng Jin, Guosheng Qu, Guosheng Qu, Chunhong Yin, Chunhong Yin, Jie Tong, Jie Tong

“…Although glycosylation of the E protein is known to influence viral infectivity and immune evasion, the specific functional roles of E protein glycosylation in ZIKV infectivity in mosquito cells remain unclear.MethodsIn this study, we generated a deglycosylation mutant ZIKV with a T156I substitution in the E protein and investigated its effects on viral replication and viral-host interactions in mosquito C6/36 cells.ResultsOur results demonstrated that the T156I mutant exhibited attenuated replication compared to the wild-type virus during the early stages (0-24 hours) post-virus infection in mosquito C6/36 cells. …”
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The Proangiogenic Potential of Rat Adipose-Derived Stromal Cells with and without Cell-Sheet Induction: A Comparative Study by Xiaoru Xu, Shuang Song, Xiangdong Liu, Yuchao Zhou, Shaojie Shi, Guoqiang Zhao, Xingxing Wang, Xutao Chen, Wenshuang Zhao, Sijia Zhang, Wei Ma, Yingliang Song

“…A functional vasculature for survival remains a challenge for tissue regeneration, which is indispensable for oxygen and nutrient supply. …”
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STUDY OF THE INFLUENCE OF THE COMPOSITION OF CULTURAL MEDIUM ON THE BASIS OF A WHITE CABBAGE ON DEVELOPMENT OF LEUCONOSTOC MESENTEROIDES AT THE PRE-FERMENTATION STAGE by V. V. Kondratenko, O. Yu. Lyalina, N. E. Posokina, A. Yu. Kolokolova, V. I. Tereshonok

“…The main task in the research process was to perform a stepby-step mathematical processing of experimental data and analyze them, to obtain functional dependencies adequately approximating the experimental data for the base (BMS) and modified (MMC) model media. …”
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Versatile machine learning algorithms for FTIR spectroscopy: differentiating crosslinked and non-crosslinked gelatin samples by Juliana Rincón-López, Eliana Álvarez-Valdés, Daniela Velez-Arango, Estefanía Rojas Zuleta, Leidy Yuliana Vargas Soto, Liliana Lellesch, Victor Alonso García Londoño, Milton Rosero-Moreano, Gonzalo Taborda-Ocampo

“…This is a mixture of amino acid polymers with a variable molecular weight and a diversity of secondary structures (α, β and γ chains). The functional and mechanical properties of the gelatin depend on the chemical and structural characteristics. …”
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An engineered M2 macrophage-derived exosomes-loaded electrospun biomimetic periosteum promotes cell recruitment, immunoregulation, and angiogenesis in bone regeneration by Zhuohao Wen, Shuyi Li, Yi Liu, Xueyan Liu, Huiguo Qiu, Yuejuan Che, Liming Bian, Miao Zhou

“…The engineered Exos derived from M2 macrophages are functionalized by surface modification of bone marrow mesenchymal stem cell (BMSC)-specific aptamers to further enhance cell recruitment, immunoregulation, and angiogenesis in bone healing. …”
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Pharmacological modulation of MRAP2 protein on murine melatonin receptor signaling by Wenqi Song, Yanchuan Li, Hongtao Xu, Yaqun Zhang, Liu Liu, Yihao Li, Xinran Wang, Yueming Du, Yining Chen, Jianjun Lyu, Lingjing Jin, Chao Zhang, Yuchen Xiao

“…Additionally, MRAP2 suppressed the membrane trafficking of MTNR1A, but promoted the surface trafficking of MTNR1B.DiscussionThese findings highlighted the complex regulatory role of MRAP2, and shed light on its diverse functions in GPCR biology and its potential implications in regulating physiological processes governed by melatonin signaling.…”
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Therapeutic potential of Cervi Cornus Colla in zebrafish bone injury: implications for aquaculture by Fengxia Xu, Limin Dong, Limin Dong, Chengxue Qin, Yanru Ren, Liang Kong, Mengru Zhang, Haitao Du, Qing Xia, Cheng Wang, Ping Wang, Ping Wang

“…IntroductionBone, as both a crucial organ with mechanical support and immune regulatory functions, profoundly influencing the growth and development of fish in aquaculture systems. …”
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Impact of Two-population α-particle Distributions on Plasma Stability by Mihailo M. Martinović, Kristopher G. Klein, Rossana De Marco, Daniel Verscharen, Roberto Bruno, Raffaella D’Amicis

“…The velocity distribution functions (VDFs) characterizing kinetic particle behavior are commonly represented as a sum of anisotropic bi-Maxwellians. …”
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Application of the Biorefinery Concept in the Processing of Crambe (<i>Crambe abyssinica</i> Hochst) Seed Defatted Meal in a Pressurized Medium by Camila da Silva, Jefferson Alessandro Schmitz, Djéssica Tatiane Raspe, Natália Stevanato, Jaqueline Hoscheid, Marcelino Luiz Gimenes, Beatriz Cervejeira Bolanho Barros, Lúcio Cardozo-Filho

“…The PF also presented adequate functional properties, such as water solubility and absorption, which suggest potential use in pet food formulations.…”
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Exploring the therapeutic and nutritional potential of camel milk: Challenges and prospects: A comprehensive review by Soumya Singh, Sonia Mann, Rhythm Kalsi, Shambhavi Singh, Neetu Kumra Taneja, Harinder Singh Oberoi, Komal Chauhan, Pankaj Taneja

“…By examining current scientific evidence and suggesting potential solutions to these challenges, this review highlights camel milk's promise as a functional food with significant health applications, presenting both nutritional security and economic opportunities on a global scale.…”
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Chlorophyllum molybdites-synthesized manganese oxide nanoparticles (MnO-NPs): morphology, biocompatibility, and anticancer properties against liver cancer (HepG2) cell line by Irfan Ullah, Asif Kamal, Malka Saba, Ulfat Ara, Driss Touhami, Abdul Wahab, Tahir Maqbool, Moona Nazish, Abdulwahed Fahad Alrefaei, Maximilian Lackner

“…FTIR analysis identified functional groups such as flavonoids, phenolics, and proteins, suggesting their role in nanoparticle stabilization and biological activity. …”
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