“Exploring the efficacy and mechanistic action of traditional Chinese medicine-derived phytochemicals in rheumatoid arthritis” by Uma Palanikumar, Rajagopal Balasubramanian, Prasanna Seenivasan, Vellaikumar Sampathrajan, Thangavelu AU

“…Introduction: Rheumatoid arthritis [RA] is an autoimmune chronic inflammatory condition that leads to joint degeneration and functional disability. The most advanced pharmacological therapies that have been available for a long time remain limited, as they are associated with adverse effects and incomplete disease remission. …”
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Distally based lateral supramalleolar flap for reconstructing distal foot defects in India: a prospective cohort study by Raja Kiran Kumar Goud, Palukuri Lakshmi, Sanujit Pawde, Madhulika Dharmapuri, Swati Sankar, Sandeep Reddy Chintha

“…Results We were able to effectively cover distal foot defects in all 10 cases. …”
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Cryo-thermal therapy reshaped the tumor immune microenvironment to enhance the efficacy of adoptive T cell therapy by Shicheng Wang, Peng Peng, Junjun Wang, Zelu Zhang, Ping Liu, Lisa X. Xu

“…The remodeling of the tumor immune microenvironment further enhanced the antitumor efficiency of ACT by increasing the proliferation of T cells, promoting activation of the effector functions of T cells and boosting the expansion of TCR clones. …”
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Cristobalite-suppressed Al–SiO2 ceramic coatings: DFT-guided nanoparticle design for durable oxidation resistance by Hao-Jie Yan, Xian-Ze Meng, Jun-Bao Chong, Hao Li, Ruo-Zhan Yin, Xiao-Feng Zhang, Lian-Kui Wu

“…The incorporation of Al inhibits and optimizes the generation of cristobalite, which suppresses the formation of cracks, thereby reducing the parabolic oxidation rate constant (kp) of the SiO2 coating by 32.4% after oxidation at 900 °C for 100 h. Density functional theory (DFT) calculations demonstrate that the introduced Al preferentially exists in a substitutional form, effectively stabilizing the K@SiO2 lattice structure by inhibiting K migration-induced cristobalite precipitation. …”
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Challenges to Seagrass Restoration in the Indian River Lagoon, Florida by Vivienne A. Main, Morgan K. Gilligan, Sarah M. Cole, Todd Z. Osborne, Ashley R. Smyth, Loraé T. Simpson

“…Studies to improve seagrass restoration efforts have targeted different functional taxa to allow for greater stability and recovery of threatened ecosystems, and excluded macro-grazers to limit losses to newly established and restored seagrasses. …”
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Changes in hemodynamics during the course of surfactant therapy in patients with hormone-dependent asthma by E. A. Аkulovа, O. V. Stepаnovа, O. V. Lovаchevа, A. A. Seyliev, K. G. Shаpovаlov, O. A. Rozenberg

“…This suggests that clinical remission during surfactant therapy in asthma patients is accompanied by changes in the functional state of the cardiovascular system.…”
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Adsorptive removal of Cr(VI) from wastewater using termite mound blended with chicken eggshell as an adsorbent: Equilibrium and kinetic approaches by Mebratu Ergete Mengistu, Yasin Ahmed Waday, Wondwosen Sime Geleta, Yigezu Mekonnen Bayisa, Dereje Tadesse Mekonnen

“…In line with this, the synthesized termite mounds blended with chicken eggshells (TMESP) adsorbent was assessed depending on their structural patterns, functional group, optical properties, and loss of mass using XRD, FTIR, UV–Vis spectra, and TGA, respectively. …”
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Analysis of Football Pitch Performances Based on Different Cutting Systems: From Visual Evaluation to YOLOv8 by Sofia Matilde Luglio, Christian Frasconi, Lorenzo Gagliardi, Michele Raffaelli, Andrea Peruzzi, Marco Volterrani, Simone Magni, Marco Fontanelli

“…This study examines the effect of two different cutting systems, a traditional ride-on mower and an autonomous mower, on the quality and functional parameters of a municipal football field. …”
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Redox‐Induced Stabilization of AMBRA1 by USP7 Promotes Intestinal Oxidative Stress and Colitis Through Antagonizing DUB3‐Mediated NRF2 Deubiquitination by Weimin Xu, Zhebin Hua, Yaosheng Wang, Wenbo Tang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Yubei Gu, Chen‐Ying Liu, Peng Du

“…In this study, it is found that AMBRA1 functions as a pro‐oxidative factor that increases oxidative stress in intestinal epithelial cells (IECs) in vitro and in vivo. …”
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Intranasal Insulin Administration Does Not Affect LH Concentrations in Men with Diabetes by Sandeep Dhindsa, Rama Chemitiganti, Husam Ghanim, Evangelina Santiago, Adnan Haider, Natalia Chaar, Mary Mok, Alexis McKee, Paresh Dandona

“…Animal studies and in vitro data have shown that insulin action and insulin responsiveness in the brain are necessary for the maintenance of the functional integrity of the hypothalamo-hypophyseal-gonadal axis. …”
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The stifling burden of climate change on African public healthcare systems by Jack Ogony, Jack Ogony, Judith Mangeni, George Ayodo, Esther Amulen, Florenc Scopas, Tusubila Juma, Michael Wagaba, Amos Deogratius Mwaka, Lena Nwanja, Sambila Princewill, Ben Oyugi, Arthy Yongo, Sitraka Rakotosolofo, Alberto Francioli, Eunison Mugamu, Julia Davies, Simon Karanja, Corrie Hannah

“…It disrupts the physical environment, natural and human systems, and the functionality of healthcare systems, acting as a multiplier threat that jeopardizes and potentially reverses decades of health gains. …”
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Advances in the role of the IGF signaling system in myelodysplastic syndromes and acute myeloid leukemia by Yifan Wang, Yifan Wang, Yifan Wang, Xinyu Dong, Xinyu Dong, Xinyu Dong, Shandong Tao, Shandong Tao, Shandong Tao, Qiuni Chen, Qiuni Chen, Qiuni Chen, Yue Chen, Yue Chen, Yue Chen, Lijuan Zhang, Lijuan Zhang, Lijuan Zhang, Yuye Shi, Yuye Shi, Yuye Shi, Zhengmei He, Zhengmei He, Zhengmei He, Liang Yu, Liang Yu, Liang Yu, Liang Yu, Chunling Wang, Chunling Wang, Chunling Wang, Chunling Wang

“…The insulin-like growth factor (IGF) signaling system comprises functionally specific ligands (IGF-I and IGF-II), receptor (IR), and binding proteins (IGFBP). …”
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High PER1 expression is associated with STK11 mutation and clinical biomarkers of immunotherapy resistance in lung adenocarcinoma by Rebecca E. Parker, Leon McSwain, Wei Zhou, Adam I. Marcus, Haian Fu, Suresh S. Ramalingam, Shirley Zhang, Melissa Gilbert-Ross

“…Abstract Aim This study characterizes the functional effects and clinical characteristics of high PER1 mRNA and high PER1 protein expression in treatment resistant lung adenocarcinoma. …”
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Molecular mechanism differences between nanoplastics and microplastics in colon toxicity: nanoplastics induce ferroptosis-mediated immunogenic cell death, while microplastics cause... by Yixian Cheng, Junjie Chen, Rui Fu, Peng Zhang, Haosong Chen, Haikun Cao, Zilong Jiang, Yuan Hong, Yifan Li, Cuiqi He, Fengjie Tao, Ting Li, Jiawei Zhang, Bo Chen, Guodong Cao

“…Abstract This study investigates the size-dependent mechanisms by which polystyrene (PS) microplastics (MPs) cause intestinal epithelial injury, focusing on the differential effects of nanoscale (100 nm) and microscale (10 μm) particles. …”
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Implantable Multifunctional Micro‐Oxygen Reservoir System for Promoting Vascular‐Osteogenesis via Remodeling Regenerative Microenvironment by Min Rui, Jiannan Mao, Hongshuai Wu, Yujian Hui, Hao Shen, Yilin Yang, Tao Ma, Kewei Ren, Juan Wang, Wenguo Cui, Qin Shi, Huilin Yang

“…The multiple pro‐regenerative effects of the implantable functionalized micro‐oxygen reservoir on bone repair are further corroborated by the enhanced vascularized bone formation in rat femoral defects, presenting a comprehensive and promising strategy for tissue repair.…”
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Piezoelectric neuron for neuromorphic computing by Wenjie Li, Shan Tan, Zhen Fan, Zhiwei Chen, Jiali Ou, Kun Liu, Ruiqiang Tao, Guo Tian, Minghui Qin, Min Zeng, Xubing Lu, Guofu Zhou, Xingsen Gao, Jun-Ming Liu

“…It operates through the synergy between the converse piezoelectric effect and the capacitive charging/discharging. Thanks to this efficient and robust mechanism, the piezoelectric neuron not only implements critical leaky integrate-and-fire functions (including leaky integration, threshold-driven spiking, all-or-nothing response, refractory period, strength-modulated firing frequency, and spatiotemporal integration), but also demonstrates small cycle-to-cycle and device-to-device variations (∼1.9% and ∼10.0%, respectively), high endurance (1010), high speed (integration/firing: ∼9.6/∼0.4 μs), and low energy consumption (∼13.4 nJ/spike). …”
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Bee pollen as a source of phenolic compounds in potato snacks by Agnieszka Nemś, Sabina Lachowicz-Wiśniewska, Ireneusz Tomasz Kapusta, Joanna Miedzianka, Agnieszka Kita, Ángel A. Carbonell-Barrachina

“…Abstract The study examined the effects of adding bee pollen to potato snacks on their chemical composition, antioxidant properties, and sensory characteristics. …”
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The role of mindfulness training supported by virtual reality in the nonpharmacological treatment of schizophrenia-research design by Andrzej Cechnicki, Adrian Chrobak, Iga Plencler, Przemysław Stankiewicz, Aneta Kalisz, Piotr Błądziński, Dawid Kruk, Stanisław Radoń, Bernadetta Szewczyk, Agata Faron-Górecka, Michał Korostyński, Marcin Siwek

“…VR-MST could support stress reduction, enhance cognitive functioning, and improve daily life in SZ patients. …”
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Wogonin Suppresses IL-10 Production in B Cells via STAT3 and ERK Signaling Pathway by Li Fan, Dongbo Qiu, Guo Huang, Jingrou Chen, Qiongli Wu, Shiqiu Xiong, Changyou Wu, Yanwen Peng, Qi Zhang

“…Wogonin (5,7-dihydroxy-8-methoxyflavone) is an ingredient of the extracts from Scutellaria baicalensis, which has documented a wide spectrum of anti-inflammatory and antitumor activities, including inhibiting regulatory T cells, regulating effector T cell functions, and mediating macrophage immunity. However, the potential effect of Wogonin on B cells has not been fully understood. …”
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Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability by Joshua D Garcia, Chenyu Wang, Ryan PD Alexander, Emmie Banks, Timothy Fenton, Jean-Marc DeKeyser, Tatiana V Abramova, Alfred L George Jr, Roy Ben-Shalom, David H Hackos, Kevin J Bender

“…Mature neocortical pyramidal cells functionally express two sodium channel (NaV) isoforms: NaV1.2 and NaV1.6. …”
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