<i>Bacillus licheniformis</i> Alleviates <i>Clostridium perfringens</i>-Induced Intestinal Injury in Mice Model by Modulating Inflammation, Apoptosis, and Cecal Microbial–Metabolic... by Yifan Zhong, Meiting Zhang, Haocheng Xu, Xiaorong Yu, Yashi Hu, Yangyi Xu, Xiao Xiao, Caimei Yang

“…This work provides new insights into the application of <i>B. licheniformis</i> as a functional microbial feed additive in livestock disease prevention.…”
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Okra polysaccharide mitigates carrageenan-induced thrombosis in mice by regulating inflammation and oxidative stress by Jinping Ni, Jinping Ni, Xiwen Cao, Xianqing Hu, Xianqing Hu, Shenwen Fu, Shenwen Fu, Shenwen Fu, Meixiu Jiang, Yuqi Ni, Yuqi Ni

“…Injury or dysfunction of endothelial cells (ECs) was assessed using RT-qPCR, Western blot and cell adhesion assays.ResultsOP can effectively improve carrageenan-induced thrombosis in tissues of mice (tail, liver, and lung) in vivo. …”
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All You Need is XOR-Convolution: A Generalized Higher-Order Side-Channel Attack with Application to XEX/XE-based Encryptions by Rei Ueno, Akira Ito, Yosuke Todo, Akiko Inoue, Kazuhiko Minematsu, Hibiki Ishikawa, Naofumi Homma

“…The proposed collision SCA effectively erases the effect of random offsets by using XOR-convolution, whereas conventional collision SCAs are ineffective in this scenario. …”
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In-vitro modulation of glucose and lipid metabolism by Lentinula edodes extracts in obesity and type 2 diabetes models by Jasmeet Kaur, Farheen Azad, Anish Murtaja Alam Khan, Mohd. Farzaan, Javed Ahmad, Humaira Farooqi, Kailash Chandra, Bibhu Prasad Panda

“…This study examines the effects of L. edodes fruiting body extract on key metabolic pathways related to glucose metabolism and lipid regulation. …”
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Shedding light on biochemical changes in single neuron-like pheochromocytoma cells following exposure to synchrotron sourced terahertz radiation using synchrotron source Fourier tr... by Palalle G. Tharushi Perera, Jitraporn Vongsvivut, Denver Linklater, Zoltan Vilagosh, Dominique Appadoo, The Hong Phong Nguyen, Mark J. Tobin, Rodney Croft, Elena P. Ivanova

“…Synchrotron sourced Fourier transform infrared (SS FTIR) microspectroscopy was employed to investigate the biological effects on the neuron-like pheochromocytoma (PC 12) cells after exposure to synchrotron sourced terahertz (SS THz) radiation. …”
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Association of critically short telomeres with brain and blood markers of ageing and Alzheimer’s disease in older adults by Asrar Lehodey, Perla Kaliman, Cassandre Palix, Robin de Florès, Edelweiss Touron, Anne-Laure Turpin, Séverine Fauvel, Florence Mézenge, Brigitte Landeau, Anne Chocat, Agathe Vrillon, Claire Paquet, Denis Vivien, Vincent de La Sayette, Gaël Chételat, Géraldine Poisnel, the Medit-Ageing Research Group

“…The effect of apolipoprotein E ε4 genotype (APOE4) was assessed on these relationships using interaction analysis. …”
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Supporting African communities to increase resilience and mental health of kids with developmental disabilities and their caregivers using the World Health Organization’s Caregiver... by Melissa Washington-Nortey, Vibian Angwenyi, Mekdes Demissie, Eva Mwangome, Tigist Eshetu, Hanna Negussie, Kimberley Goldsmith, Andrew Healey, Merga Feyasa, Girmay Medhin, Amanuel Belay, Temesgen Azmeraw, Medhanit Getachew, Rahel Birhane, Carophine Nasambu, Tsegereda Haile Kifle, Angela Kairu, Beatrice Mkubwa, Fikirte Girma, Rehana Abdurahman, Ruth Tsigebrhan, Liya Tesfaye, Leonard Mbonani, Nadine Seward, Tony Charman, Andrew Pickles, Erica Salomone, Chiara Servili, Edwine Barasa, Charles R. Newton, Charlotte Hanlon, Amina Abubakar, Rosa A. Hoekstra

“…Methods This is a 2-arm multi-site hybrid type-1 effectiveness implementation cluster randomised controlled superiority trial. …”
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Impact of Climate and Soil on Plant Dynamics and Ecosystem Stability in Argan Orchards by Maryem Telmoudi, Chaima Afi, Naima Chabbi, Said Labbassi, Assma Oumasst, Mohamed Ouknin, Rachid Bouharroud, Abdelaziz Mimouni, Mimoun El Kaoua, Driss Hsissou, Abdelghani Tahiri, Naima Ait Aabd

“…However, how communities respond to the effects of fluctuating disturbances remains unclear. …”
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APOE modulates ferroptosis to drive macrophage polarization toward the M2 type and enhance PTC migration and invasion by Ziwen Li, Min Li, Sinuo Sun, Yu Bin, Suwei Zuo, Ronghua Huo, Jiayin Song, Gang Xue, Xu Lin, Jingfang Wu

“…Results: In PTC tissues, Fe2+ accumulation was lower than in adjacent normal tissues, while the expression of APOE, xCT, GPX4, and FTH1 was significantly higher compared to adjacent normal tissues. Functional assays demonstrated that APOE inhibited ferroptosis in PTC cells, potentially by regulating ferroptosis through the PI3K/AKT1 pathway and modulating Fe2+ accumulation. …”
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Assessing neonatal brain glymphatic system development using diffusion tensor imaging along the perivascular space and choroid plexus volume by Ting Peng, Ying Lin, Xin Xu, Jiaqi Li, Miaoshuang Liu, Chaowei Zhang, Xiaohui Liao, Xiaoshan Ji, Zhongmeng Xiong, Zhuoyang Gu, Xinyi Cai, Tianli Tao, Yajuan Zhang, Lixuan Zhu, Deyi Zhuang, Xianghui Huang, Man Xiong, Peng Zhang, Jungang Liu, Guoqiang Cheng

“…Abstract Purpose Neonatal brain development constitutes a critical period of structural and functional maturation underpinning sensory, motor, and cognitive capacities. …”
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Long-term Metformin Alters Gut Microbiota and Serum Metabolome in Coronary Artery Disease Patients After Percutaneous Coronary Intervention to Improve 5-year Prognoses: A Multi-omi... by Ruilin Zhou, Qingyang Wu, Hao Qian, Liang Wang, Guangcheng Liu, Bin Zhang, Wei Wu, Shuyang Zhang

“…Metformin tended to have more positive effects on the commensal flora and metabolic profiles, which may explain its beneficial effects on cardiovascular health. …”
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Sex-dependent efficacy of sphingosine-1-phosphate receptor agonist FTY720 in mitigating Huntington’s disease by Jingyun Wu, Irene Santos-Garcia, Ivan Eiriz, Thomas Brüning, Aleš Kvasnička, David Friedecký, Tuula A. Nyman, Jens Pahnke

“…Histological analyses of the brain revealed delayed accumulation of activated astrocytes contributing to the preservation of the neural microenvironment by reducing neuroinflammation.The extent of FTY-related disease improvement was sex-dependent. Motor functions and body weight improved mostly in female mice with sustained estrogen levels, whereas males had to compensate for the ongoing, disease-related testis atrophy and the loss of androgen production.Our study underscores the beneficial therapeutic effects of FTY on HD involving endogenous steroid hormones and their important anabolic effects. …”
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Evaluation of a patient decision aid for opportunistic salpingectomy and salpingectomy as sterilization method to prevent ovarian cancer by Malou E. Gelderblom, Charlotte Fisch, Jurgen M. J. Piek, Laura A. M. vanLieshout, Justine Briet, Lauren Bullens, Sjors F. P. J. Coppus, Inge Ebisch, Alexandra A. vanGinkel, Rafli van deLaar, Natascha deLange, Marloes Maassen, Huy Ngo, Angele L. M. Oei, Brenda Pijlman, Brigitte Slangen, Regina The, Dineke Smedts, Caroline Vos, Joanna IntHout, Joanne A. deHullu, Rosella P. M. G. Hermens

“…Main reasons for choosing opportunistic salpingectomy were the risk‐reducing effect of ovarian cancer (N = 311; 90%) and the lack of functionality of the fallopian tubes after childbearing (N = 320; 92%). …”
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Inhibition of carbohydrate digestive enzymes by a complementary essential oil blend: in silico and mixture design approaches by El Hassania Loukili, Mouhcine Fadil, Amal Elrherabi, Mohammed Er-rajy, Mohamed Taibi, Khalil Azzaoui, Khalil Azzaoui, Rachid Salghi, Rachid Sabbahi, Mohammed M. Alanazi, Larbi Rhazi, Aleksandar Széchenyi, Aleksandar Széchenyi, Mohamed Siaj, Belkheir Hammouti

“…A statistical mixture design was employed to evaluate different EO ratios for their inhibitory effects on α-amylase and α-glucosidase. Additionally, density functional theory (DFT) calculations and molecular docking simulations were conducted to assess the key metabolites' electronic properties and interaction potential with target enzymes.ResultsGC-MS analysis identified 32 metabolites in P. graveolens, with citronellol (18.67%), eucalyptol (13.30%), and 2-octen-1-ol (8.12%) as major components. …”
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Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti by Maria A. A. Bertonceli, Vitor D. C. Cristo, Ivo J. Vieira, Francisco J. A. Lemos, Arnoldo R. Façanha, Raimundo Braz-Filho, Gustavo V. T. Batista, Luis G. M. Basso, Sérgio H. Seabra, Thalya S. R. Nogueira, Felipe F. Moreira, Arícia L. E. M. Assis, Antônia E. A. Oliveira, Kátia V. S. Fernandes

“…Additionally, neither rotenoids nor the CS/TPP–β-CD–rot nanocomposite exerted cytotoxic effects, confirming their favorable safety profile. …”
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Quinoa–Peanut Relay Intercropping Promotes Peanut Productivity Through the Temporal Optimization of Soil Physicochemical Properties and Microbial Community Composition in Saline So... by Xiaoyan Liang, Rao Fu, Jiajia Li, Yinyu Gu, Kuihua Yi, Meng Li, Chuanjie Chen, Haiyang Zhang, Junlin Li, Lan Ma, Yanjing Song, Xiangyu Wang, Jialei Zhang, Shubo Wan, Hongxia Zhang

“…The quinoa–peanut relay intercrop pattern (IP) is a promising planting system that utilizes the biological advantages of quinoa to improve soil ecological functions and productivity. However, the effects of IP on soil physicochemical and biological properties and the yield formation of the combined peanut crop are still unclear. …”
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Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities by Valeria Romanucci, Rita Pagano, Solveigh C. Koeberle, Andreas Koeberle, Minh Bui Hoang, Sonia Di Gaetano, Domenica Capasso, Michele Francesco Maria Sciacca, Valeria Lanza, Carmelo Tempra, Fabio Lolicato, Armando Zarrelli, Danilo Milardi, Giovanni Di Fabio

“…Interestingly, <b>EP4</b> exhibited substantial cytotoxic effects against various human cancer cell lines (HeLa, A375, WM266) while sparing normal cells (HDFs). …”
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Thiacloprid Exposure Induces Oxidative Stress, Endoplasmic Reticulum Stress, and Apoptosis in the Liver of Mauremys reevesii by Shuqin Lin, Yunjuan Xiao, Siyu Li, Liyan Tang, Haitao Shi, Meiling Hong, Li Ding

“…In this study, we aimed to evaluate the effects of THI on oxidative stress, endoplasmic reticulum stress (ERS), and apoptosis in aquatic turtles. …”
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Identification of novel antioxidant and anti-inflammatory peptides from bovine hemoglobin by computer simulation of enzymolysis, molecular docking and molecular dynamics by Xuan-Ying Xin, Chao-Hui Ruan, Yi-Hui Liu, Huai-Na Jin, Sung-Kwon Park, Sun-Jin Hur, Xiang-Zi Li, Seong-Ho Choi

“…Due to the structural diversity and complex mechanisms of action of bioactive peptides, screening for specific functional peptides is often challenging. To efficiently screen bioactive peptides with antioxidant and anti-inflammatory effects from bovine hemoglobin, we employed bioinformatics methods to perform virtual enzymatic hydrolysis using online tools and predicted the bioactivity, toxicity, and sensitization scores of the resulting peptides. …”
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LRP6 regulates growth in Litopenaeus vannamei via the Wnt/β-catenin signaling pathway by Sheng Wang, Xiaodi Wang, Hao Yang, Xuanzheng Di, Haoyang Li, Bin Yin, Ziwei Liu, Chaozheng Li, Jianguo He

“…However, little is known about its effect on growth performance in economic animal including shrimp. …”
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