Novel drug targets for monkeypox: From viral to host proteins by Zhaozhong Zhu, Qin Sun, Yunhai Xu, Youya Niu, Fei Yang, Shuidong Feng

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The burden and determinants of cognitive impairment among individuals with chronic diseases in Ethiopia: A systematic review and meta-analysis by Addisu Getie, Melaku Bimerew, Mihretie Gedfew, Baye Tsegaye Amlak, Tegene Atamenta Kitaw, Adam Wondmieneh

“…Introduction: Cognitive impairment is a medical condition caused by neurodegeneration, marked by a gradual decline in neurological, motor, psychological, and cognitive domain functions, as well as daily activities. It primarily affects individuals with conditions such as Alzheimer's disease, stroke, HIV/AIDS, diabetes mellitus, cancer, epilepsy, dementia, and other chronic illnesses, as well as older adults. …”
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Sustained response to guselkumab regardless of baseline characteristics in patients with active psoriatic arthritis and inadequate response to TNF inhibitors: results from the phas... by Iain B McInnes, Laura C Coates, Philipp Sewerin, Frédéric Lavie, Mohamed Sharaf, Miriam Zimmermann, Michela Efficace

“…Subgroups were defined by baseline demographics, disease characteristics and prior/ongoing therapies.Methods Patients with active PsA (tender joint count (TJC) and swollen joint count (SJC) both ≥3) and TNFi-IR were randomised 2:1 to receive guselkumab 100 mg at week 0, week 4, then every 8 weeks through week 44 or to placebo with cross-over to guselkumab 100 mg at week 16 (early escape) or week 24 (planned). Guselkumab effect on joints (American College of Rheumatology (ACR) 20/50/70, enthesitis, dactylitis), skin (Psoriasis Area and Severity Index 90/100, Investigator’s Global Assessment 0/1), patient-reported outcomes (PROs) (Functional Assessment of Chronic Illness Therapy–Fatigue, Health Assessment Questionnaire–Disability Index) and composite outcome measures (PsA Disease Activity Score low disease activity, minimal disease activity) were evaluated by baseline patient age, sex, body mass index, SJC, TJC, PsA duration, %body surface area, C reactive protein, pain Visual Analogue Scale, number of prior TNFi and discontinuation reason, and conventional synthetic disease-modifying antirheumatic drug status. …”
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UBE2J1 is identified as a novel plasma cell-related gene involved in the prognosis of high-grade serous ovarian cancer by Yunjie Tian, Ruoyu Dong, Yingxia Guan, Ying Wang, Wei Zhao, Jun Zhang, Shan Kang

“…Finally, the effects of key markers on HGSOC cells were evaluated via Cell Counting Kit-8 (CCK-8), Transwell, colony formation, wound healing, immunofluorescence and in vivo tumor growth assays. …”
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Biofabrication of copper oxide nanoparticles using Dalbergia sisso leaf extract for antibacterial, antibiofilm and antioxidant activities by Muhammad Hussnain Siddique, Maimona Sadia, Saima Muzammil, Muhammad Saqalein, Asma Ashraf, Sumreen Hayat, Saba Saba, Arif Muhammad Khan, Abeer Hashem, Graciela Dolores Avila-Qezada, Elsayed Fathi Abd-Allah

“…FTIR indicated presence of different functional groups that were used as reducing and capping agents while XRD analysis showed crystalline phase structure for the nanoparticles. …”
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Pericytes in castration-resistant prostate cancer associated with disease progression and immunotherapy response: insights from single-cell analysis by Yifeng Qiu, Yuhan Wang, Jiahe Liu, Kai Sun, Shigeo Horie, Zhitong Bing, Qi Hou

“…Subsequently, we thoroughly delineated the phenotypic and functional characteristics of the CRPC-pericytes subpopulation. …”
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Platelet-rich Plasma versus Corticosteroid Injection for the Treatment of Lateral Epicondylitis – A Prospective Randomised Controlled Study by Suryakanth Kalluraya, Anand Varma, Gujjala Venkata Naga Yeswanth

“…Conclusion: We concluded that patients treated with PRP had significantly reduced pain, increased functional activity, less recurrence and without requirement of any further intervention, outperforming corticosteroid injection effect at the end of 6 months follow up.…”
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Construction and Completion of the Knowledge Graph for Cow Estrus with the Association Rule Mining by Zhiwei Cheng, Luyu Ding, Cheng Peng, Helong Yu, Baozhu Yang, Ligen Yu, Qifeng Li

“…We utilized Boolean functions derived from association rule learning to validate the ability of the rules to identify normal estrus. …”
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Investing in the future: an integrated model for analysing user attitudes towards Robo-advisory services with AI integration by Sandeep Singh, Atul Kumar

“…Moreover, the moderation effect of gender partly supports the overall model. …”
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Investigation on the Nonlinear Vibration Characteristics of Current-Carrying Crescent Iced Conductors under Aerodynamic Forces, Ampere’s Forces, and Forced Excitation Conditions by Xiaohui Liu, Haobo Liang, Guangyun Min, Chuan Wu, Mengqi Cai

“…The amplitude-frequency response functions of the nonlinear forced primary resonances and super-harmonic and subharmonic resonances of the system are derived by using the multiscale method. …”
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Fatigue outcomes following COVID-19: a systematic review and meta-analysis by Rachael A Evans, Trudie Chalder, Fiona Gaughran, Kim Poole-Wright, Ismail Guennouni, Olivia Sterry

“…A mixed effects meta-regression of 35 prospective articles calculated change in fatigue overtime. …”
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Suture tape augmentation in the management of anterior cruciate ligament ruptures: a systematic review and meta-analysis by Peiyuan Tang, Yangbin Cao, Ying Zhu, Han Tan, Haoxuan Li, Wenfeng Xiao, Ting Wen, Jun Zhang, Yusheng Li, Shuguang Liu

“…This meta-analysis synthesizes prior research to assess the effectiveness of additional SA in treating ACL tears. …”
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Incorporating a dynamic extraocular muscle simulation model into the undergraduate ophthalmic curriculum by Erqian Wang, Qianyi Yu, Haiyan Xu, Shuang Geng, Enhua Shao, Zhikun Yang, Meifen Zhang, Hui Li

“…All students were given 5-point quizzes on the anatomical and functional basics of extraocular muscles before the lecture(Q1), after the lecture(Q2), and after simulator practice/video-review(Q3). …”
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Immune pre-stimulation by injected yeast beta-glucan as a strategy to prevent calf diarrhea and bovine respiratory disease during the first 74 days of age by Fang Yan, Zhihong Zhang, Xiaorong Zhan, Wenqian Yang, Junhu Yao, Xiurong Xu

“…Studies have shown that immune stimulants such as yeast beta-glucan can induce the innate immune system to acquire memory and improve their non-specific defense functions. This trial was conducted to evaluate the prophylactic effect of intraperitoneal injection of yeast β-glucan after birth on diarrhea in Holstein calves during the first 74 days of age.MethodsA total of 52 healthy newborn Holstein calves (body weight 39.3 ± 0.82 kg) were enrolled and randomly assigned into two groups (n = 26 in per group): 1) placebo group (CON), and 2) intraperitoneal injection with yeast β-glucan solution (0.1 g/mL, 50 mg/kg body weight) at 3 and 6 days of age (IP). …”
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First Experience of Multifocal and Toric Extended Depth of Focus Intraocular Lenses Implantation (Short-Term Analysis) by К. B. Pershin, N. F. Pashinova, А. Yu. Tsygankov, E. A. Antonov

“…Aim. Analysis of the functional results of new IOL with an extended depth of focus implantation a in the short-term (6 months) follow-up period.Patients and methods. …”
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An efficient and resilient energy management strategy for hybrid microgrids inspired by the honey badger's behavior by Ahmed A. Shaier, Mahmoud M. Elymany, Mohamed A. Enany, Nadia A. Elsonbaty, Marwa M. Tharwat, Marwa M. Ahmed

“…The honey badger algorithm (HBA) proved its cost-effectiveness and efficiency by achieving the lowest overall operating cost and the highest efficiency of 95.893 %. …”
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Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy by Sangeetha Madhavan, Shravni Deshmukh, Mark Cummings, Aditi Doshi, Kourosh Rezania, Sally Freels, Gina Sawa

“…Primary outcomes included feasibility, safety, and disease progression measured by the ALS Functional Rating Scale‐Revised (ALSFRS‐R). Adherence and adverse effects were monitored throughout. …”
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The Use of Economic and Mathematical Modeling in Assessing the Competitiveness of Tourism Industry Enterprises by S. N. Medvedeva, V. P. Pavlyuk

“…The implementation of such a system is directly related to the analysis and assessment of the whole variety of conditions and factors for the functioning of the subjects of the tourism industry.…”
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Exploring the Anti-depression Mechanism of Polygonatum ordoratum Based on GEO Database Combined with Network Pharmacology and Molecular Docking Technology by Zhenxu JIANG, Chaoxing WANG, Yuliang WANG, Hong ZHAO, Yu SHEN, Shiqing SUN, Yongzhe MA, Mingming SONG, Yu ZHANG

“…Conclusion: Yuzhu may exert its antidepressant effects through inflammatory response, oxidative stress, and prostaglandin synthesis pathways.…”
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The impact of urbanization on land use land cover change using geographic information system and remote sensing: a case of Mizan Aman City Southwest Ethiopia by Addis Bikis, Muluye Engdaw, Digvijay Pandey, Binay Kumar Pandey

“…Deforestation for urban functions, including timber production, construction materials, and firewood, adversely affects the environment. …”
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