Comprehensive Structural, Chemical, and Optical Characterization of Cu₂ZnSnS₄ Films on Kapton Using the Automated Successive Ionic Layer Adsorption and Reacti... by Perla J. Vázquez-González, Martha L. Paniagua-Chávez, Lizette A. Zebadua-Chavarria, Rafael Mota-Grajales, C. A. Meza-Avendaño, Enrique Campos-González, A. Escobosa-Echavarría, Yaoqiao Hu, Aldo E. Pérez-Ramos, Manuel-Matuz, Carlos A. Hernández-Gutiérrez

“…The investigation explored the effects of varying deposition cycles (40, 60, 70, and 80) and annealing treatments on the films. …”
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Acetylation suppresses breast cancer progression by sustaining CLYBL stability by Xinyue Deng, Chenglong Ma, Xingyu Chen, Ming Yi, Qianhua Cao, Ruocen Liao, Xingyu Lei, Longchang Bai, Bin Zhao, Yingnan Wang, Zhuoyang Shen, Liujing Wu, Chenfang Dong, Zhijun Dai

“…The acetylation patterns of CLYBL and the related regulatory functions were detected by high resolution mass spectrometry, immunoprecipitation assays, and western blot analysis. …”
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Diffusion imaging changes in the treated tract following focused ultrasound thalamotomy for tremor by Erin L. Mazerolle, Robyn Warwaruk-Rogers, Paul Romo, Tejas Sankar, Sarah Scott, Conrad P. Rockel, Samuel Pichardo, Davide Martino, Zelma H.T. Kiss, G. Bruce Pike

“…No significant correlations were detected between diffusion measures and clinical effects, suggesting that microstructural changes in the treated portion of the DRTT alone do not fully explain tremor reduction and motivating additional research using higher spatial resolution diffusion imaging and multimodal approaches such as integrating diffusion and functional magnetic resonance imaging data. …”
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Meta-analysis of Germline Whole-exome Sequencing in 1435 Cases of Testicular Germ Cell Tumour to Evaluate Disruptive Mutations Under Dominant, Recessive, and X-linked Inheritance M... by Zeid Kuzbari, Charlie F. Rowlands, Isaac Wade, Alice Garrett, Chey Loveday, Subin Choi, Beth Torr, Kevin Litchfield, Alison Reid, Robert Huddart, Peter Broderick, Richard S. Houlston, Clare Turnbull

“…Our study was well powered to detect rare variation of moderate/high effect sizes (odds ratio [OR] ≥5), but power diminished for modest effect sizes (OR <5). …”
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Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK by Heather Walton, David Dajnak, Mike Holland, Dimitris Evangelopoulos, Dylan Wood, Christian Brand, Nosha Assareh, Gregor Stewart, Andrew Beddows, Shawn YC Lee, Daniela Fecht, Yunzhe Liu, Bethan Davies, Anna Goodman, Tuan Vu, Sean Beevers

“…Literature concentration–response functions were combined with baseline rates from routine statistics/other sources. …”
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Lotus seed (Nelumbinis semen) extract: anticancer potential and chemoprofiling by in vitro, in silico and GC-MS studies by Vijaya Jyothi Mallela, Mithun Rudrapal, D. S. N. B. K. Prasanth, Praveen Kumar Pasala, Atul R. Bendale, Soumya Bhattacharya, Sahar M. Aldosari, Sahar M. Aldosari, Johra Khan, Johra Khan

“…Lotus seeds, also known as Nelumbinis semen, has been utilized for over 7,000 years as vegetable, functional food and medicine. In this study, we primarily investigated the anticancer effects of lotus seed extracts, particularly of the methanolic extract (MELS) on cell proliferation inhibition, apoptosis induction and cell cycle arrest in ovarian cancer cell lines. …”
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Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH by Yang Huixia, Ding Ning, Qing Shi, Hao Yinju, Zhao Cilin, Wu Kai, Li Guizhong, Zhang Huiping, Ma Shengchao, Bai Zhigang, Jiang Yideng

“…Importantly, the ferroptosis inhibitor ferrostatin-1 (Fer-1) effectively reverses Dex-induced ferroptosis in MC3T3-E1 cells. …”
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Single-cell transcriptomics link gene expression signatures to clinicopathological features of gonadotroph and lactotroph PitNET by T. Elise Potthoff, Carolin Walter, Daniela Jeising, Daniel Münter, Archana Verma, Eric Suero Molina, Walter Stummer, Martin Dugas, Wolfgang Hartmann, Matthias Dottermusch, Lea Altendorf, Ulrich Schüller, Sophia Scheuermann, Christian Seitz, Thomas K. Albert, Kornelius Kerl

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Cecropin anisaxin-2S has in vitro immunomodulatory, but not antiproliferative and antiviral properties by Jovana Majstorović, Jovana Majstorović, Anush Arakelyan, Željka Trumbić, Jan Kamiš, Jan Kamiš, Mikolaj Adamek, Tomislav Rončević, Vedrana Čikeš Čulić, Jiří Kyslík, Martin Palus, Ivan Fiala, Ivona Mladineo, Ivona Mladineo

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Conversion of T Effector Cells Into T Regulatory Cells in Type 1 Diabetes/Latent Autoimmune Diabetes of Adults by Inhibiting eIF5A and Notch Pathways by Rafiqi SI, Aldasouqi A, Paparodis RD, Dewan S, Farooqi A, Faisal S, Nemat Y, Salim N, Qureshi S, Mahmood A, Tovar Y, Jun JY, Kalinoski AL, Mirmira RG, Jaume JC, Imam S

“…GAD65+GC7+anti-DLL4 treatment plasticized Tregs withstanding a proinflammatory milieu mimicking T1D/LADA, and the plasticized Tregs exhibited a stable and suppressive functional phenotype. Furthermore, GAD65+GC7+anti-DLL4 treatment had no adverse effects on immune cells.The present approach is a multipronged approach involving the inhibition of eIF5a and Notch pathways that addresses the upregulation of immune tolerance, differentiation, and proliferation of cytotoxic T cells and alleviates β-cell dysfunction. …”
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Oral treatment with Rosa multiflora fructus extract modulates mast cells in canine atopic dermatitis by Ha-Young Shin, Ha-Young Shin, Ha-Young Shin, Sang Hun Shin, Hee Soon Shin, Hee Soon Shin, Hyun-Jin Tae, Hyun-Jin Tae, Hyun-Jin Kim, Hyun-Jin Kim, Jeong Ho Hwang

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Cooperative mechanisms of oxide ion conduction in tellurites with secondary bond interactions and Grotthuss-like processes by Zhenyu Zhu, Guanqun Cai, Yuxiang Feng, Juping Xu, Shengqi Chu, Pengfei An, Jianrong Zeng, Wen Yin, Yu Gu, Xiaojun Kuang, Junliang Sun

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In vivo CRISPR screening identifies POU3F3 as a novel regulator of ferroptosis resistance in hepatocellular carcinoma via retinoic acid signaling by Yu Tian, Xin Bao, Shan Lei, Youcai Huang, Xiaoling Wang, Yanyang Tu, Qinglian He, Feixiang Zhang, Haicheng Xu, Milad Ashrafizadeh, Gautam Sethi, Furong Wang, Zhirui Zeng

“…Knockdown of POU3F3 significantly enhanced the pro-ferroptotic and inhibitory effects of sorafenib on HCC cells by suppressing retinoic acid metabolism. …”
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Genetic Analysis and Fine Mapping of QTLs for Stigma Exsertion Rate in Rice by Hanyuan Yang, Yin Zhou, Pingbo Li, Enyu Liu, Ping Sun, Yiting Ao, Rongjia Liu, Haozhou Gao, Zherui Xu, Ping Yang, Xinyue Wang, Guanjun Gao, Qinglu Zhang, Lizhong Xiong, Yuqing He

“…A combination of sequencing, expression and haplotype analysis revealed that a single nucleotide variation (T to C) in the 5’UTR region of LOC_Os01g72020 (OsBOP1) was likely to be the functional variation for qSE1. Collectively, our work has laid a foundation for cloning the genes responsible for SER, and demonstrated that the Hua6S allele of qSE1 and the B805D allele of qSE9 can effectively increase SER, which could make important contributions to the genetic improvement of MSLs aimed at improving hybrid seed production.…”
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Reducing Cd Uptake by Wheat Through Rhizosphere Soil N-C Cycling and Bacterial Community Modulation by Urease-Producing Bacteria and Organo-Fe Hydroxide Coprecipitates by Junqing Zhang, Shuangjiao Tang, Hao Wei, Lunguang Yao, Zhaojin Chen, Hui Han, Mingfei Ji, Jianjun Yang

“…The bioavailability of heavy metals is profoundly influenced by their interactions with active soil components (microorganisms, organic matter, and iron minerals). However, the effects of urease-producing bacteria combined with organo-Fe hydroxide coprecipitates (OFCs) on Cd accumulation in wheat, as well as the mechanisms underlying these effects, remain unclear. …”
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Multiomics insights into BMI-related intratumoral microbiota in gastric cancer by Kang Liu, Zhengchen Jiang, Zhengchen Jiang, Yubo Ma, Ruihong Xia, Yingsong Zheng, Kailai Yin, Chuhong Pang, Li Yuan, Li Yuan, Xiangdong Cheng, Xiangdong Cheng, Zhuo Liu, Bo Zhang, Shi Wang

“…There is a lack of studies exploring the effect of BMI on gastric cancer from the perspective of intratumoral microbiota. …”
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Longitudinal health-related quality of life in patients with pancreatic cancer stratified by treatment: a nationwide cohort studyResearch in context by Anne M. Gehrels, Pauline A.J. Vissers, Mirjam A.G. Sprangers, Nienke M. Fijnheer, Esther N. Pijnappel, Lydia G. van der Geest, Geert A. Cirkel, Judith de Vos-Geelen, Marjolein Y.V. Homs, Geert- Jan Creemers, Martijn W.J. Stommel, Lois A. Daamen, Marc G. Besselink, Johanna W. Wilmink, Hanneke W.M. van Laarhoven

“…In R-PAC, hepatic symptoms and health care satisfaction improved while role and social functioning deteriorated and eating related problems, side effects and fear of future health increased during treatment. …”
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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors by Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

“…Yet, the molecular and cellular mechanisms by which either receptor functions to mediate its inhibitory effects are still poorly understood. …”
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Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmaco... by Jiacheng Shen, Jiacheng Shen, Jiacheng Shen, Yuxuan Fang, Yuxuan Fang, Nan Xu, Nan Xu, Hongyi Chen, Hongyi Chen, Miao Zhu, Miao Zhu, Dan Li, Dan Li, Zewen Chu, Masataka Sunagawa, Yanqing Liu, Yanqing Liu, Haibo Wang, Haibo Wang, Guoqing Li, Guoqing Li

“…., has significant immunosuppressive and anti-inflammatory effects. However, the specific mechanisms of TPL-regulated effects on RA-FLS cytoskeleton and inhibition of invasive metastasis are not yet fully explored. …”
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A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors by Shuai Zhao, Shuai Zhao, Shuai Zhao, Lin Cheng, Xingzhao Ji, Xingzhao Ji, Shengnan Sun, Shengnan Sun, Shengnan Sun, Yi Liu, Yi Liu, Qiang Wan, Qiang Wan, Qiang Wan

“…Furthermore, we conducted cellular functional experiments to examine the effects of ZNF514 overexpression or knockdown on renal clear cell carcinoma cell proliferation, migration, and invasion.ResultsOur study found that ZNF514 expression was elevated in tumor tissues than in normal tissues in most tumor types. …”
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