Showing 69,081 - 69,100 results of 73,353 for search 'effective function', query time: 0.37s Refine Results
  1. 69081
  2. 69082

    Expression of the cholesterol transporter SR-B1 in melanoma cells facilitates inflammatory signaling leading to reduced cholesterol synthesis by Oliver Eckel, Madalina A. Mirea, Anna Gschwendtner, Martina Pistek, Katharina Kinslechner, Clemens Röhrl, Herbert Stangl, Markus Hengstschläger, Mario Mikula

    Published 2025-05-01
    “…Our study shows that functional SR-B1 is linked to inflammatory signaling, which reduces cholesterol synthesis, while enabling melanoma cell survival during chemotherapy treatment.…”
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  3. 69083

    The synergy of hybrid desiccants and membrane-assisted techniques for enhancing dehumidifier efficiency by Nitesh Kumar, Ganesha A, Girish H, Anala Krishna Harsha, Matam Vidya Shekar, Sampath Suranjan Salins, Shiva Kumar

    Published 2024-12-01
    “…In this setup, MgCl2 functions as the desiccant, while zeolites serve as the enhancing additive. …”
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  4. 69084

    Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer by Pathea Shawnae Bruno, Aneeta Arshad, Maria-Raluca Gogu, Natalie Waterman, Rylie Flack, Kimberly Dunn, Costel C. Darie, Anca-Narcisa Neagu

    Published 2025-01-01
    “…Post-translational modifications (PTMs) of proteins dynamically build the buffering and adapting interface between oncogenic mutations and environmental stressors, on the one hand, and cancer cell structure, functioning, and behavior. Aberrant PTMs can be considered as enabling characteristics of cancer as long as they orchestrate all malignant modifications and variability in the proteome of cancer cells, cancer-associated cells, and tumor microenvironment (TME). …”
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  5. 69085

    Suspended Lithium Nitrate‐Based Electrolytes: Electrostatic Interactions for Mutually Rewarding Interface Optimization Strategies by Wenjing Zhang, Zhenguo Zhang, Hongtao Zhang, Yang Luo, Xinjian Liu, Zhonghao Rao

    Published 2025-05-01
    “…The suspended LiNO3 particles exhibit dual functionality: LiNO3 enhances the compatibility between the electrode and the electrolyte by affecting the Li+ solvation environment and preferentially adsorb on the electrode surface; moreover, the in situ formed LiNxOy‐rich EEI by LiNO3 decomposition with accelerated Li⁺ transport kinetics, effectively suppresses parasitic reactions and improves rate performance. …”
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  6. 69086

    Characterization and modeling of additively manufactured Ti-6Al-4V alloy with modified surfaces for medical applications by Hüray Ilayda Kök, Tonya Andreeva, Sebastian Stammkötter, Cindy Reinholdt, Osman Akbas, Anne Jahn, Florian Gamon, Sandra Fuest, Mirko Teschke, Miriam Schäfer, Michael Müller, Alexander Koch, Ole Jung, Mike Barbeck, Andreas Greuling, Ralf Smeets, Ralf Smeets, Jörg Hermsdorf, Rumen Krastev, Philipp Junker, Meike Stiesch, Frank Walther

    Published 2025-04-01
    “…This work summarizes the investigations on additively manufactured Ti-6Al-4V alloy of the research unit 5250 “Mechanism-based characterization and modeling of permanent and bioresorbable implants with tailored functionality based on innovative in vivo, in vitro and in silico methods” funded by the Germany Research Foundation (DFG).…”
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  7. 69087

    CCDC86-BHLHE40-ATF3 axis promotes aerobic glycolysis and tumor development in glioma by Jinping Liu, Dingyu Du, Yukai Huang, Jie Tian, Xuhui Wang, Longyi Chen, Feng Wang

    Published 2025-11-01
    “…Furthermore, ATF3 emerged as a downstream target gene of CCDC86, as its knockdown could counteract the oncogenic effects induced by CCDC86 overexpression in glioma cells. …”
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  8. 69088

    Enhanced UV Resistance of Poly(methyl methacrylate) Through Schiff Base and Metal Oxide Nanoparticle Incorporation by Ahmed Hussein, Emad Yousif, Malath Rasheed, Dina Ahmed, Muna Bufaroosha, Mohammed Kadhom

    Published 2025-03-01
    “…FTIR and weight loss measurements assessed modified PMMA's UV stabilization. The effectiveness of functional groups was assessed by monitoring their growth. …”
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  9. 69089

    Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility by Jurij Froese, Marco Mandalari, Monica Civera, Stefano Elli, Isabel Pagani, Elisa Vicenzi, Itzel Garcia-Monge, Daniele Di Iorio, Saskia Frank, Antonella Bisio, Dominik Lenhart, Rudolf Gruber, Edwin A. Yates, Ralf P. Richter, Marco Guerrini, Seraphine V. Wegner, Kay Grobe

    Published 2024-12-01
    “…However, these enhanced interactions may reduce Omicron’s ability to move through the HS-rich ECM to effectively find ACE2 receptors and infect cells, raising the question of how to mechanistically explain HS-associated viral movement. …”
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  10. 69090
  11. 69091

    SIRT7 deletion inhibits Glaesserella parasuis-mediated inflammatory responses in porcine alveolar macrophages by Hao Zheng, Hao Zheng, Baoxin Wang, Baoxin Wang, Xia Dong, Xia Dong, Junjing Wu, Liangyu Shi, Liangyu Shi, Jing Zhang, Jing Zhang, Hongbo Chen, Hongbo Chen, Ao Zhou, Ao Zhou

    Published 2025-06-01
    “…Functional enrichment analysis further indicated the involvement of these DEGs in tight junction pathway, PI3K-Akt signaling pathway, actin cytoskeleton regulation, cGMP-PKG signaling pathway, Hippo signaling pathway, and TNF signaling pathway. …”
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  12. 69092

    Revitalising Brewers' Spent Grains and Enriching With Biogenic Compounds Through the Fermentation of Fructophilic Lactic Acid Bacteria and Yeasts by Alessandro Stringari, Ali Zein Alabiden Tlais, Stefano Tonini, Daniela Pinto, Giorgia Mondadori, Pasquale Filannino, Raffaella Di Cagno, Marco Gobbetti

    Published 2025-06-01
    “…ABSTRACT The large output of spent grains from the brewing industry presents environmental concerns but also offers promising nutritional and functional potential for valorization by researchers and industrial stakeholders. …”
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  13. 69093

    Developing and validating utility parameters to establish patient-reported outcome-based perioperative symptom management in patients with lung cancer: a multicentre, prospective,... by Rui Zhang, Wei Dai, Qiang Li, Shaohua Xie, Qiuling Shi, Yuanqiang Zhang, Wenhong Feng, Xiaoqing Liao, Yunfei Mu, Xing Wei, Chuanmei Wu, Heling Zhou, Xuemei Cheng, Yanhua Jiang, Jintao He, Xiaojun Yang

    Published 2019-10-01
    “…We will determine the optimal time points for follow-up using the generalised linear mixed-effects models. The MDASI-LC interference-measured functional status will be used as the anchor for the alert thresholds.Ethics and dissemination Ethics Committee of Sichuan Cancer Hospital approved this study on 16 October 2017 (No. …”
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  14. 69094

    Degradation and Corrosion of Metal Components in High-Temperature Fuel Cells and Electrolyzers: Review of Protective Approaches by Pavel Shuhayeu, Olaf Dybiński, Karolina Majewska, Aliaksandr Martsinchyk, Monika Łazor, Katsiaryna Martsinchyk, Arkadiusz Szczęśniak, Jarosław Milewski

    Published 2025-06-01
    “…The review concludes with a synthesis of current best practices and future directions, emphasizing the need for integrated, multi-functional solutions to achieve the lifetimes required for full commercialization. …”
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  15. 69095

    Association of ethylene oxide exposure with serum neurofilament light chain levels among American adults by Xiuwen Yang, Huaili Feng, Ting You, Zhaoyi Liu, Fanwei Sun, Chengzhi Chen, Jingfu Qiu

    Published 2025-03-01
    “…ObjectiveTo explore the relationship between Ethylene oxide (EO) expousure and serum neurofilament light chain (NfL).MethodA data of 559 adults from the 2013–2014 National Health and Nutrition Examination Survey (NHANES) was analyzed, and the relationship between log-transformed EO hemoglobin adducts (HbEO) and serum NfL levels was assessed using multiple linear regression models and restricted cubic spline functions. Stratified analysis was conducted to explore the correlations within different subgroups. …”
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  16. 69096

    Cross-linked multifunctional bilayer polymer buffer for enhanced efficiency and stability in perovskite solar cells by Yuheng Li, Lin Li, Haipeng Zeng, Chunxiang Lan, Shaomin Yang, Ziwei Zheng, Miaomiao Zeng, Yingying Shi, Kai Gao, Lianmeng Cui, Rui Guo, Jing Guo, Bin Hu, Yaoguang Rong, Haibing Xie, Xiong Li

    Published 2025-07-01
    “…Consequently, this design effectively reduces undesirable metal/ion interdiffusion during device fabrication and operation. …”
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  17. 69097

    Impact softening performance of low melting point alloy/copper foam composite phase change materials by Jingjing Song, Minzu Liang, Yuliang Lin, Leilei Wu, Jiakai Guo, Wen Liang, Yuwu Zhang

    Published 2025-08-01
    “…The deformation failure mechanism and the strain rate softening effect of low melting point alloy/copper foam composite phase change material (CPCM) under impact loading were investigated using a macro-fine-micro multi-scale analysis method. …”
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  18. 69098

    Active Biodegradable Packaging Films Based on the Revalorization of Food-Grade Olive Oil Mill By-Products by Assamae Chabni, Celia Bañares, Irene Sanchez-Rey, Carlos F. Torres

    Published 2024-12-01
    “…This allows their use as protective packaging and potential carriers of bioactive oils to enhance the nutritional and functional qualities of packaged foods.…”
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  19. 69099
  20. 69100

    New Role for L-Arginine in Regulation of Inducible Nitric-Oxide-Synthase-Derived Superoxide Anion Production in Raw 264.7 Macrophages by Michaela Pekarova, Antonin Lojek, Hana Martiskova, Ondrej Vasicek, Lucia Bino, A. Klinke, D. Lau, Radek Kuchta, Jaroslav Kadlec, Radimir Vrba, Lukas Kubala

    Published 2011-01-01
    “…In conclusion, our data demonstrated that simultaneous induction of NADPH oxidase, together with the iNOS enzyme, can result in the uncoupled state of iNOS resulting in the production of functionally important levels of O2∙- soon after macrophage activation with LPS. …”
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