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68981
Advanced epoxy composites for tribological Applications: Investigating the role of hybrid ceramic and lubricant fillers
Published 2025-09-01“…Enhancing these properties through the use of functional fillers presents a promising approach; however, the combined effects of reinforcing and lubricating agents within epoxy remain underexplored. …”
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68982
How to Deal with Pulpitis: An Overview of New Approaches
Published 2025-01-01“…<b>Background:</b> Traditional root canal therapy (RCT) effectively removes diseased or necrotic pulp tissue and replaces it with inorganic materials. …”
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68983
RETRACTED ARTICLE: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells
Published 2021-01-01“…The Bax and cleaved-caspase-3 genes involved in apoptosis executive functions were significantly increased in a dose-dependent manner in BGC-823 and MGC-803 cells. …”
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68984
Labiaplasty and its current status
Published 2016-12-01“…CONCLUSION: Labiaplasty using the wedge resection technique relieved personal discomfort and provided functional and aesthetic improvement. Due to the lack of validation and standardization of labiaplasty techniques, further clinical research should be performed.…”
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68985
Photochemical Synthesis of Polycyclic Phosphonium Salts as Efficient Anticancer and Antibacterial Agents
Published 2025-03-01“…ABSTRACT Phosphorus‐containing functional materials have diverse applications in optoelectronics and bioscience owing to their unique properties. …”
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68986
Ethnobotany of Lao Isan Ethnic Group from Na Chueak District, Maha Sarakham Province, Northeastern Thailand
Published 2025-05-01“…. & A.Camus) T.Q.Nguyen have high functional importance in local cultural and medical practices. …”
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68987
Evaluation of Antioxidant, Antibacterial and Fastness Properties of Erythrina abyssinica Extracts on Cotton Fabric Using Biomordants
Published 2025-03-01“… Due to the toxicity of synthetic dyes, natural dyes have been touted as possible alternatives owing to their eco-friendliness and ability to impart bio-functional properties, such as antibacterial, antifungal and antioxidant properties, especially when natural dyes are mordanted using with biomordants. …”
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68988
Living photosynthetic micro/nano-platforms: Engineering unicellular algae for biomedical applications
Published 2025-09-01“…As autotrophic biosystems, unicellular algae uniquely possess multi-functions, including oxygen generation, dynamic motility, fluorescence imaging, and programmable biosynthesis. …”
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68989
Cross-Temperature FeFETs Enabling Long- and Short-Term Memory for Reservoir Computing Network
Published 2025-01-01“…This study investigates the device characteristics and reliability of ferroelectric field-effect transistors (FeFETs) with a focus on their temperature-dependent performance. …”
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68990
Improving photovoltaic water pumping system performance with PSO-based MPPT and PSO-based direct torque control using real-time simulation
Published 2025-05-01“…The outcomes of these simulations closely matched those from MATLAB/Simulink, further confirming the proposed PSO-based control strategy’s effectiveness, robustness, and reliability.…”
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68991
Y-box Protein-1 Regulates the Expression of Collagen I in Hepatic Progenitor Cells via PDGFR-β/ERK/p90RSK Signalling
Published 2017-01-01“…This study aims to explore the functions of YB-1 in hepatic progenitor cells (HPCs). …”
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68992
Nitrogen‐Doped Multiwalled Carbon Nanotubes Trigger Immune Responses and Inhibit Fat Deposition
Published 2024-12-01“…However, it's unclear to their effects on fat metabolism. Here, it is demonstrated that nitrogen‐doped carboxylate‐functionalized MWCNTs (N‐MWCNTs) inhibit fat deposition both in vivo and in vitro. …”
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68993
Coffee Pulp from Azores: A Novel Phytochemical-Rich Food with Potential Anti-Diabetic Properties
Published 2025-01-01“…A decrease in glucose uptake in Caco-2 cells was found, but not in fructose, suggesting selective inhibition of SGLT1 and potential antidiabetic effects. These results show that Azorean coffee pulp has potential as a sustainable and bioactive ingredient for incorporation into functional foods or dietary supplements.…”
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68994
Physicochemical properties of turmeric (Curcuma longa L.) and black pepper (Piper nigrum) enriched ice cream
Published 2024-01-01“…The effect of turmeric powder and a mix of turmeric powder and black pepper on the physicochemical properties of ice cream samples was examined. …”
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68995
Comprehensive approach to the choice of therapy in patients with osteoarthritis at the first visit to the doctor. Expert consensus (literature review and resolution)
Published 2021-06-01“…The article discusses: current clinical guidelines for the management of patients with OA; most common problems in the management of patients with OA in real clinical practice; goals of treatment strategies for OA taking into account the risk factors for its progression; an algorithm of pain relief during initial treatment in patients with OA; prevention of OA exacerbations with the use of basic structure-modifying drugs; recommendations for the choice of non-steroidal anti-inflammatory drugs.According to experts, a rational approach to the treatment of OA is based on the combined use of non-drug and pharmacological methods with constant monitoring of therapy regimens and side effects. These recommendations can be considered disease-modifying strategies that in many cases allow improving functional status and achieving long-term remission in patients with OA.…”
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68996
Perturbation of enzyme structure by nano-metal organic frameworks: A question mark on their safety-by-design?
Published 2024-11-01“…These structural changes were accompanied by a marked decrease in enzymatic activity, particularly with CuIm nMOFs showing the most substantial inhibitory effects. Our findings highlight the profound impact of nMOFs on enzyme structures and functions, emphasising the need for comprehensive assessments of nMOFs' potential toxicity and understanding the aspects of their safety-by-design.…”
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68997
Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap
Published 2025-08-01“…The observed structural fluctuations/conformational changes demonstrate the effect of N‐glycans on protein stability. These findings offer new insights into the molecular basis of Fc‐mediated functions and provide valuable information for the design of next‐generation therapeutics.…”
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68998
Resveratrol and Its Metabolite as Potential Allosteric Regulators of Monoamine Oxidase A Activity in the Brain and Liver Under Chronic Predator Stress
Published 2025-05-01“…<b>Conclusions</b>: The primary outcomes of the study include the identification of the role of hepatic MAO-A in the development of anxiety-like behavior, as well as the determination of resveratrol dose ranges at which it functions as an allosteric modulator of MAO-A activity.…”
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68999
Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis
Published 2024-10-01“…We further identified that KW-2449 functioned as a ULK1 (Unc-51-like kinase 1) inhibitor to block ULK1 kinase activity in autophagy. …”
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69000
Reconfigurable Three-Switch Leg Multi-Port Boost Inverters With Novel Modulation Schemes for Hybrid DC/AC Microgrid Systems
Published 2025-01-01“…The proposed control modulation scheme effectively addresses crossover issues in modulation signals, resulting in enhanced AC voltage gain, improved DC bus utilization, and optimized power transfer among DC and AC ports. …”
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