Irreversible electroporation synergizes with oncolytic virus enhances the infiltration of cytotoxic T lymphocytes in the tumor immune microenvironment: a leap from focal therapy to... by Shaogang Wang, Zhi-Yu Xia, Jia-Cheng Xiang, Jin-Zhou Xu, Jian-Xuan Sun, Qi-Dong Xia

“…The strategy leverages IRE’s functional preservation and OVs’ targeted lytic activity to synergistically enhance therapeutic efficacy while minimizing invasiveness.…”
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Leveraging quantitative structure-activity relationships to design and optimize wall material formulations for antioxidant encapsulation via spray drying by Hugo M. Lisboa, Alexandre Lúcio, Rogério Andrade, Ana Maria Sarinho, Janaina Lima, Leonardo Batista, Maria Eduarda Costa, Amanda Nascimento, Matheus B. Pasquali

“…This study provides a resource-efficient strategy combining predictive modeling and empirical approaches with broad applications in functional food, nutraceutical, and pharmaceutical development, where stability and bioavailability are critical.…”
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Implications of Pleurotus ostreatus solid-state bioprocessing on the nutritional composition, protein structure, and anti-hypertensive and anti-inflammatory potential of local bean... by Sara Muñoz-Pina, Kateryna Khvostenko, Jorge García-Hernández, Ana Heredia, Ana Andrés

“…Specifically, this approach can be beneficial for preventing obesity and promoting overall metabolic health. Therefore, the effect of Pleurotus ostreatus solid-state fermentation on the nutritional quality, amino acid profile, and functionality of two traditional Valencian bean varieties were analyzed as potential ingredients for food formulation. …”
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Quality control of blood components: selection of laboratory testing methods by E. N. Kalinina, N. S. Vildanova, E. S. Kormshchikova, E. A. Konovalova, N. V. Isaeva, T. V. Krivokorytova, M. E. Kovtunova, K. A. Vorobiev

“…One of the main tasks of blood service institutions is the procurement of high-quality transfusion media, the effectiveness of which directly depends on the functioning of the safety system. …”
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Balancing on carbon storage and ecological security in urban areas: The case of Dongguan city, China by Xinyi Wang, Fenzhen Su, Fengqin Yan, Vincent Lyne, Yikun Cui, Bin He, Rong Fan

“…Current and future national urban policies must therefore enhance carbon sink functions of ecosystems while maintaining spatial ecological structure networks. …”
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Sex differences in the sensitization of prenatally programmed hypertension by Baojian Xue, Alan Kim Johnson, Alexander G. Bassuk, Alexander G. Bassuk, Alexander G. Bassuk

“…A more complete understanding of the functional capabilities of the sex hormones and their interactions with prohypertensive factors in offspring, from early life to aging, would likely lead to new insights into the basis of sex differences in programmed hypertension. …”
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Nanoparticle-mediated SIRT1 inhibition suppresses M2 macrophage polarization and hepatocarcinogenesis in chronic hepatitis B by He Zhang, Feng Yuan, Nan Zhao, Wenqiang Tang, Pengwei Zhao, Chunfa Liu, Shan Chen, Xiaolin Hou, Changyou Xia, Jun Chu

“…Synthesized and characterized MNPs successfully delivered SIRT1 inhibitors, effectively inhibiting M2 macrophage polarization in vitro. …”
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Modelling of sanitary wastewater composition and operation of a small membrane bioreactor wastewater treatment plant with denitrification and nitrification by Mitrinović David S., Perović Marija S., Kovačević Srđan R., Popović Miodrag R., Radibratović Zorana Z.

“…In the next step, a model for wastewater treatment simulation was created by using the BioWin software (Envirosim Associates, USA) in order to examine functioning of the plant and test the effects of several possible modifications of the process. …”
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Downregulation of PTPRK Promotes Cell Proliferation and Metastasis of NSCLC by Enhancing STAT3 Activation by Xuting Xu, Dong Li, Jin Liu, Zhihong Ma, Huilian Huang, Lishan Min, Licheng Dai, Shunli Dong

“…These results suggested that PTPRK functions as a novel tumor suppressor in NSCLC, and its suppressive ability may be involved in STAT3 activation.…”
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LncRNA C7orf13 facilitates cell proliferation and metastasis in nasopharyngeal carcinoma via targeting miR‐449c/miR‐28‐5p‐FMNL2 axis by Peng Xie, Yujie Zhang, Jin Shang, Hanxu Yu, Mingyu Du, Jian Shu, Qiang Wei, Zeyu Zhu, Xia He

“…Moreover, C7orf13 knockdown weakened FMNL2‐mediated cell invasion and migration. Finally, functional experiments revealed that the positive effect of C7orf13 on cell migration and invasion was mediated by the miR‐449c/miR‐28‐5p‐FMNL2 axis. …”
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An Anisotropic Gold‐Palladium Heterostructured Nanosystem for Synergistically Overcoming Radioresistance and Enhancing Melanoma Radioimmunotherapy by Cheng Chen, Yuqi Huang, Wandong Wang, Minghao Chao, Weiguo Sun, Yinghui Kong, Guan Jiang, Yong Gao, Fenglei Gao

“…The nanosystem integrates photothermal, radiotherapeutic, and immunomodulatory functions. Under 1064 nm laser irradiation, APSMR generates reactive oxygen species (ROS) via plasmon‐driven catalysis and Mn‐mediated Fenton‐like reactions. …”
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Identification of novel human microcephaly-linked protein Mtss2 that mediates cortical progenitor cell division and corticogenesis through Nedd9-RhoA by Aurelie Carabalona, Henna Kallo, Maryanne Gonzalez, Liliia Andriichuk, Ellinoora Elomaa, Florence Molinari, Christiana Fragkou, Pekka Lappalainen, Marja W Wessels, Juha Saarikangas, Claudio Rivera

“…The cerebral cortex, which is responsible for higher cognitive functions, relies on the coordinated asymmetric division cycles of polarized radial glial progenitor cells for proper development. …”
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A compliant teleoperation control method based on real-time dynamic impact force feedback and operator-sensing by Yiming Bin, Jinjun Duan, Lingyu Wang, Minhong Wan, Qiulan Huang, Hongtao Wu

“…Design/methodology/approach – This paper established the conventional mapping relationship between the teleoperation device and the robot, and found out the reasons of the impact of jitter on slave robots; the paper then implemented the bilateral force feedback of force/dimension at the mapping point, and iteratively solved the feedback force of each time according to its functional compensation relationship, thus forming the bilateral force feedback method of dynamic impact feedback and operator-sensing of the teleoperation system. …”
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ZNF8 Orchestrates with Smad3 to Promote Lung Metastasis by Recruiting SMYD3 in Breast Cancer by Wenwen Geng, Junhua An, Ke Dong, Hailu Zhang, Xiuyuan Zhang, Yuchen Liu, Rong Xu, Yifan Liu, Xiaofen Huang, Haiyun Song, Wei Yan, Aihua Sun, Fuchu He, Jian Wang, Haidong Gao, Chunyan Tian

“…SMYD3 inhibition by BCI121 effectively prevents ZNF8‐mediated lung metastasis. …”
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Neurophysiological approaches for managing pain in multiple sclerosis: a mini review by Samar S. Ayache, Samar S. Ayache, Samar S. Ayache, Samar S. Ayache, Moussa A. Chalah, Moussa A. Chalah, Moussa A. Chalah

“…This condition can significantly impact the individuals' functionality, including their capacity to engage in professional activities. …”
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Disruption of Spore Coat Integrity in <i>Bacillus subtilis</i> Enhances Macrophage Immune Activation by Bolang Liao, Yongxian Han, Zheng Wei, Xuhong Ding, Yan Lv, Xiaoqin Sun, Mingming Yang

“…In this study, we investigated the immunostimulatory effects of spores deficient in six key coat proteins: SpoIVA, SafA, CotE, CotX, CotZ, and CgeA. …”
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Toll-like receptor 4-mediated inflammatory stimulation in Kupffer cell enhances arsenite-induced liver fibrosis by triggering hepatic stellate cell activation by Qian Song, Meitong Zhou, Rui He, Heng Diao, Lili Fan, Chenglong Tu, Xiong Chen, Dapeng Wang

“…However, the specific functions of these cells in As-induced LF remain to be elucidated. …”
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Alleviating Continuous Cropping Obstacles in Celery Using Engineered Biochar: Insights into Chemical and Microbiological Aspects by Chia-Chia Lin, Ya-Hui Chuang, Fo-Ting Shen, Wen-Hsin Chung, Chi-Yu Chen, Yu-Ting Liu, Yi-Cheng Hsieh, Yu-Min Tzou, Shih-Hao Jien

“…Using liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF/MS) for both target and suspect analyses, along with Biolog EcoPlate™ to track the functional diversity of soil bacteria, the study examined chemical and microbiological interactions at varying WP400 application rates. …”
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Automated MIP-based in-tip dispersive micro-solid phase extraction for determination of ketoprofen in environmental water: A proof of concept and performance evaluation by Mohammed T. Shehabeldeen, Fotouh R. Mansour, Samah F. El-Malla, Aya A. Abdella

“…The MIP was prepared using chitosan as the functional monomer, glutaraldehyde as the crosslinker, and ketoprofen (KTP) as the template molecule. …”
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A comparative evaluation of retention of record bases fabricated digitally in various types of posterior palatal seal area by Swapna Bettanapalya Venkatesh, Vaishnavi M. Nayak, Kavishma Sulaya, Smitha Sammith Shetty

“…Objectives: Intraoral scanners used for the fabrication of milled and 3D-printed complete dentures simplify the procedure. However, its effectiveness in recording the functional peripheral seal area needs to be researched. …”
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