NELL2 suppresses epithelial-mesenchymal transition and induces ferroptosis via notch signaling pathway in HCC by Shiqi Liu, Haomin Wu, Pengjie Zhang, Haonan Zhou, Di Wu, Yifan Jin, Hongwei Yang, Ruilin Xing, Yubo Wu, Gang Wu

“…Consequently, NELL2 may serve as a novel therapeutic target, potentially functioning as a tumor suppressor gene in HCC.…”
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Dropout and completion in iCBT for university students: Insights from a thematic analysis by Jurrijn A. Koelen, Lisa de Koning, Matilda K. Nottage, Anke M. Klein, Claudia M. van der Heijde, Peter Vonk, Reinout W. Wiers

“…Implications regarding setting expectations, participant selection, interactive functionalities, personalized feedback, and the role of therapist guidance are discussed.…”
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Strong, antioxidant, and biodegradable gelatin methacryloyl composite hydrogel for oxidative stress protection in Schwann cells by Hongyang Han, Dongcao Ji, Shu Yang, Bo Pang, Xi Chen, Jiaqi Zhu, Jiaqi Zhu, Wenxin Cao, Wenxin Cao, Tao Song

“…However, its poor mechanical strength and functional monotony restrict broader clinical applications of this material. …”
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Antibacterial Mechanism of Robusta Coffee Carbon Dots against Staphylococcus aureus by Lin ZHANG, Shen YANG, Ritian JIN, Duo LIANG, Siqi WANG, Rong LIN

“…The results indicated that Robusta coffee carbon dots exhibited good dispersibility with negative charges and abundant surface functional groups such as O-H, C-H, and C-O. Furthermore, the MIC value of Robusta coffee carbon dots against Staphylococcus aureus was 250 μg/mL, effectively inhibiting bacterial growth within 8 hours by damaging the cell membrane of Staphylococcus aureus leading to leakage of intracellular substances and promoting the production of reactive oxygen species (ROS). …”
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Food Fortification and Nutrition Enhancement Strategies in the Agri-food Sector in Support of the Farm-To-Fork Initiative of the European Union by Mihaela MIHAI, Călina CIONT, Cristina MARCHIȘ, Ligia OLAR-POP, Oana Lelia POP

“…,zinc-biofortified rice), functional food development (e.g., probiotic yogurts), and microencapsulation (e.g., encapsulated fish oil in bread against oxidation). …”
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Cargo Analysis and MRI‐Based Therapeutic Assessment of Iron Oxide Labelled Extracellular Vesicles of Hypoxia Human Stem Cells in Ischemic Stroke by Shannon Helsper, Li Sun, Richard Jeske, Chang Liu, Jacob Athey, Xuegang Yuan, Samuel C. Grant, Yan Li

“…Predominantly due to paracrine effects in vivo, hMSC‐secreted extracellular vesicles (EVs) are at the forefront of these investigations. …”
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Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy by Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu

“…Abstract Nanodrug delivery systems (NDDS) have demonstrated broad application prospects in disease treatment, prevention, and diagnosis due to several advantages, including functionalization capability, high drug‐loading capacity, drug stability protection, and the enhanced permeability and retention (EPR) effect. …”
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Integrative analysis of exosomal ncRNAs and their regulatory networks in liver cancer progression by Farzin Mirzaei-nasab, Ahmad Majd, Yousef Seyedena, Nazanin Hosseinkhan, Najma Farahani, Mehrdad Hashemi

“…Moreover, exosomal RNA was shown to effectively reflect tissue-specific gene expression changes. …”
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Data-Driven Monitoring of Probiotic Fermentation in Fruit Juices Using Near-Infrared Spectroscopy and Aquaphotomics: An Innovative Approach to Food Valorization by Lueji Regatieri, Flora Vitalis, Erika Bujna, Quang Duc Nguyen, Zoltan Kovacs

“…The nutritional effects of fruit juices, combined with the added value of a probiotic, provide a plant-based fortified functional food. …”
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Rehabilitation and physical activity during treatment of various types of cancer by Weronika Woźniak, Monika Gaszyńska, Antonina Drzewiecka, Artur Drzewiecki, Wiktor Korczak, Maria Anna Madejska, Aleksandra Rudzka, Wojciech Falkowski, Anna Krysińska, Jakub Magielski

“…Through their analysis, it is possible to demonstrate the impact of rehabilitation and physical activity on the functioning of patients during cancer treatment. Keywords: rehabilitation, exercise cancer, breast cancer, lung cancer, gastrointestinal cancer Brief description of state of the art: The negative effects of treatment can affect any system in the human body, so rehabilitation is necessary to assist the patient in the process of cancer therapy, which can have a significant positive impact on treatment. …”
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Changes in Resting fMRI Networks in Patients with Severe Traumatic Brain Injury During Therapeutic Rhythmic Transcranial Magnetic Stimulation (Case Report) by A. S. Zigmantovich, E. V. Sharova, M. М. Kopachka, A. S. Smirnov, E. V. Alexandrova, Yu. V. Kotovich, Ya. I. Deza-Araujo, M. V. Stern, E. M. Troshina, I. N. Pronin

“…Aim of the study: to evaluate the effect of therapeutic rhythmic transcranial magnetic stimulation (rTMS) on fMRI resting state networks (RSN) in PCU after severe TBI.   …”
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Unconventional Hexagonal Close‐Packed High‐Entropy Alloy Surfaces Synergistically Accelerate Alkaline Hydrogen Evolution by Ting‐Hsin Hu, Cheng‐Yu Wu, Zong Ying He, Yi Chen, Liang‐Ching Hsu, Chih‐Wen Pao, Jui‐Tai Lin, Chun‐Wei Chang, Shang‐Cheng Lin, Rachel Osmundsen, Lee Casalena, Kun Han Lin, Shan Zhou, Tung‐Han Yang

“…Electrochemical measurements, operando XAS analysis, and density functional theory unveil that the binding strengths of H* and OH* intermediates on the active Pt and Ir sites can be weakened and strengthened to a moderate level, respectively, by mixing non‐active Ru, Rh, and Pd atoms with Pt and Ir atoms within the HCP HEA with strong synergistic electronic effects.…”
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A novel peptide from yak ameliorates hypoxia-induced cardiac dysfunction via targeting gut microbiota and HIF-1α pathway by Feiyan Yang, Guangfan Qu, Yuchi Wu, Pingsheng Zhong, Zhongxing Chu, Zeyu He, Yuyan Wang, Yiping Tang, Shuguo Sun, Feijun Luo

“…These findings suggest that T3 may be a potential candidate for developing functional foods to reduce hypoxia-induced cardiac dysfunction.…”
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Impact of Ovarian Suspensory Ligament Rupture on Surgical Stress in Elective Ovariohysterectomy in Bitches by Pauline Silva dos Santos, Victor Mendes de Oliveira, Keli Cristina Corbellini Oltramari, Vitória Santos Guimarães, Sarah Fernandes, Carla Eduarda dos Santos Ferreira, Agatha Costa Malinski, Vinícius Cardoso de Oliveira, Jéssica Corrêa, Izabelle Moutinho, Dalila Moter Benvegnú, Camila Dalmolin, Gabrielle Coelho Freitas, Fabíola Dalmolin

“…The physical parameters, complete blood count, glucose levels, erythrocyte sedimentation rate, and neutrophil oxidative and phagocytic functions were evaluated pre-surgery and at 6, 12, 24, and 48 h, as well as 10 days after. …”
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The FOXO pathway mediates a conserved mechanism of antioxidant defense against microplastic-induced toxicity in Aurelia coerulea polyps and mouse liver by Xiaoxiao Chen, Yina Zhu, Feng Wu, Liangzhi Li, Yi Wang, Blessing Danso, Zhixiao Yang, Xiao Peng, Marina. pozzolini, Qinglong Tang, Liang Xiao, Xiaojie Dai

“…Molecular docking showed conserved regions between polyps NLK and mouse Mapk13, indicating similar kinase activities, but overall structural and functional differences suggest species-specific. This finding provide new insights into understanding the mechanisms of toxicity of MPs to different organisms.…”
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O-GlcNAcylation of METTL3 drives hepatocellular carcinoma progression by upregulating MCM10 expression in an m6A-IGF2BP3-dependent manner by Zhen Chen, Jiaxin Yin, Zhongqi Feng, Yanlai Zhang, Li Liang, Xiaojun Wang, Kai Wang, Ni Tang

“…Despite the significance of METTL3 in hepatocellular carcinoma (HCC), its post-translational modifications and their functional implications in HCC remain poorly understood. …”
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Associations of Haplotypes Upstream of IRS1 with Insulin Resistance, Type 2 Diabetes, Dyslipidemia, Preclinical Atherosclerosis, and Skeletal Muscle LOC646736 mRNA Levels by Selma M. Soyal, Thomas Felder, Simon Auer, Hannes Oberkofler, Bernhard Iglseder, Bernhard Paulweber, Silvia Dossena, Charity Nofziger, Markus Paulmichl, Harald Esterbauer, Franz Krempler, Wolfgang Patsch

“…These data suggest a role for LOC646736 in human insulin resistance and warrant further studies on the functional effects of this locus.…”
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Spatiotemporally programmable cascade hybridization of hairpin DNA in polymeric nanoframework for precise siRNA delivery by Feng Li, Wenting Yu, Jiaojiao Zhang, Yuhang Dong, Xiaohui Ding, Xinhua Ruan, Zi Gu, Dayong Yang

“…Nanoframework provides stability and ease of functionalization, which helps address the complexity–scalability–error of DNA. …”
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Optimization of Angoumois Grain Moth (Sitotroga cerealella Olivier) Infestation in Stored Grains as Influenced by Some Botanical Powders by Mahmudul Hasan, Kazi Shahanara Ahmed, Nayan Chandra Howlader, Md. Mahfuzul Hasan, Mita Saha Puja, Most. Safia Farhana, Maruf Hasan Nikson

“…The maximum percent of germination was noted in bishkathali (Persicaria lapathifolia) powder at 1 g/100 g seed, and moreover, bishkathali powder functions more effectively for limiting infestation percent. …”
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Carbon spheres: an option to improve the germination and growth process of Pinus devoniana under in vitro and greenhouse conditions by Juan Luis Ignacio-De la Cruz, Francisco Gabriel Granados-Martínez, David Ricardo Poiré-De la Cruz, Juan Manuel Sánchez-Yáñez, Nelly Flores-Ramírez, Carmen Judith Gutiérrez-García, Orlando Hernández-Cristóbal, Crisanto Velázquez-Becerra, Lada Domratcheva-Lvova

“…These findings substantiate the assertion that CSs exert a beneficial effect on the germination and growth of P. devoniana seeds, with could be an option in reforestation projects.…”
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