Deletion of PTHrP nuclear localization sequence and carboxyl terminus leads to lung dysplasia by Youyu LI, Yaoyao JIN, Jiawen ZHOU, Min CUI, Chenyu XIAO, Yongjie ZHANG

“…In order to further investigate the in vivo functions of PTHrP nuclear localization sequence (NLS) and C-terminus, Professor Andrew Karaplis and Professor Dengshun Miao et al. used genetic engineering technology to knock in (KI) a stop codon (TGA) after the 84th amino acid sequence of PTHrP and constructed a mouse model expressing only PTHrP (1–84), but not NLS and C-terminus, namely PTHrP NLS and C-terminal knockout mice (also PTHrP KI mice). …”
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Exploring the Molecular Mechanism and Role of Glutathione S-Transferase P in Prostate Cancer by Shan Huang, Hang Yin

“…<b>Aims:</b> To investigate the effect of Glutathione metabolism in prostate cancer pathogenesis. …”
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Confidence evaluation for feature selection in expanded feature space based on density of states by Koki Obinata, Yasuhiko Igarashi, Kenji Nagata, Keitaro Sodeyama, Masato Okada

“…We demonstrate the effectiveness of our proposed methods through their application to a crystal structure dataset. …”
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The Green Synthesize of Zinc Oxide Catalyst Using Pomegranate Peels Extract for the Photocatalytic Degradation of Methylene Blue Dye by Atheel Alwash

“…FTIR spectra identify the presence of many active functional groups for the pomegranate extract which is ideal to bind with zinc acetate to produce the ZnO nanoparticles during the preparation method. …”
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Acupotomy for Musculoskeletal Pain: Exploring Therapeutic Potential and Future Directions by Hu J, Tong H, Zhang J, Jiang L

“…Preliminary evidence suggests that acupotomy holds promise in effectively alleviating pain, improving functional outcomes, and facilitating myofascial tissue healing in individuals with musculoskeletal pain. …”
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Integrating AI in Education: An Analysis of Factors Influencing the Acceptance, Concerns, Attitudes, Competencies and Use of Generative Artificial Intelligence Among Polish Teacher... by Łukasz Tomczyk, Aleksandra Majkut

“…The results indicate that the most frequently used functions of AI are information retrieval and text translation, while more advanced applications remain marginally used in educational contexts. …”
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Fall prediction in a quiet standing balance test via machine learning: Is it possible? by Juliana Pennone, Natasha Fioretto Aguero, Daniel Marczuk Martini, Luis Mochizuki, Alexandre Alarcon do Passo Suaide

“…Currently, clinical assessments of gait and posture include functional evaluations, objective, and subjective scales. …”
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The Impact of Knee Orthoses on Lameness and Weight Distribution in Canine After Rupture of the Cranial Cruciate Ligament by Aljaž Muršec, Monika Pavlović, Tomaž Lampe, Vladimira Erjavec

“…This study investigates the effectiveness of custom-made knee orthoses as a conservative treatment for recent cranial cruciate ligament ruptures in dogs. …”
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Efficacy of Manual Therapy and Electrophysical Modalities for Treatment of Cubital Tunnel Syndrome: A Randomized Interventional Trial by Michał Wieczorek, Tomasz Wolny

“…The use of neurodynamic techniques, ultrasound, and low-level laser therapy in the conservative treatment of mild to moderate forms of CuTS has a beneficial therapeutic effect.…”
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Characteristics and outcomes of patients with Guillain–Barré syndrome who were admitted to the intensive care unit: a retrospective observational study by Samah Alqahtani, Hasan M Al-Dorzi, Hatim Arishi, Ahmad Peeran, Felwa Bin Humaid, Farhan Zayed Alenezi, Jesna Jose, Musharaf Sadat, Naser Alotaibi, Yaseen M Arabi

“…At maximum follow-up, Hughes Functional Grading scores were 0 (full recovery) in 11 patients (25.5%), 1–3 in 18 (41.8%), 4–5 in 12 (27.9%), and 6 (death) in two (4.6%, both in the MV group), with higher median Hughes score in the MV group (3 versus 0.5). …”
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Chronic thromboembolic pulmonary hypertension after an acute pulmonary embolism: fundamental concepts of diagnosis and review of current treatment options by N. A. Cherepanova, D. V. Duplyakov

“…Currently, the only drug with a high class of evidence for this group of patients is riociguat. A positive effect on exercise tolerance, functional class, and hemodynamic parameters has been shown in the CHEST-1,2 studies. …”
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A survey of multimodal composite editing and retrieval by Suyan Li, Fuxiang Huang, Lei Zhang

“…A comprehensive evaluation and usage guide is needed to fully assess its capabilities and limitations, since it complements and extends the functionalities provided by multimodal retrieval systems. …”
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Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice. by Maiko Yamaji, Marwa Mahmoud, Ian M Evans, Ian C Zachary

“…NRP1 is expressed in smooth muscle cells (SMC) but the functional role of NRP1 in SMC has not been elucidated. …”
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Spatiotemporal Analysis of Eco-Geological Environment Using the RAGA-PP Model in Zigui County, China by Xueling Wu, Jiaxin Lu, Chaojie Lv, Liuting Qin, Rongrui Liu, Yanjuan Zheng

“…The Three Gorges Reservoir Area in China presents a critical conflict between industrial development and ecological conservation. It functions as a key hub for water management, energy production, and shipping, while also serving as a vital zone for ecological and environmental protection. …”
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Sustainable Supercritical Carbon Dioxide Extraction of Value-Added Lignan from Sesame Meal: Achieving Green Neuroprotection and Waste Valorization by Optimizing Temperature, Solven... by Kuo-Ching Jan, Mohsen Gavahian

“…This study aimed to develop an optimized supercritical carbon dioxide extraction to isolate sesame meal’s functional compound (lignans) and assess their neuroprotective effects. …”
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Human Genome Editing: Managing Technological Risks through Legal Means by A. A. Troitskaya, K. A. Sharlovskiy

“…Objective: to determine theoretical approaches to the legal regulation of reprogenetic editing, taking into account the risk-oriented approach and the practice of regulation of such breakthrough technologies in different jurisdictions; to outline further regulatory and managerial steps to be taken for the technology development.Methods: general scientific methods of analysis and synthesis, classification, system and functional approaches; specific scientific methods: formal-legal, comparative-legal, and historical-legal.Results: the research shows the possible approaches to the regulation of genetic editing for reproductive purposes. …”
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Dysfunction of the CNS-heart axis in mouse models of Huntington's disease. by Michal Mielcarek, Linda Inuabasi, Marie K Bondulich, Thomas Muller, Georgina F Osborne, Sophie A Franklin, Donna L Smith, Andreas Neueder, Jim Rosinski, Ivan Rattray, Andrea Protti, Gillian P Bates

“…In the symptomatic animals, pronounced functional changes were visualised by cardiac MRI revealing a contractile dysfunction, which might be a part of dilatated cardiomyopathy (DCM). …”
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Inference and dynamic simulation of malaria using a simple climate-driven entomological model of malaria transmission. by Israel Ukawuba, Jeffrey Shaman

“…Given the crucial role of climate in malaria transmission, many mechanistic models of malaria represent vector biology and the parasite lifecycle as functions of climate variables in order to accurately capture malaria transmission dynamics. …”
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Combined x-ray diffraction, electrical resistivity, and ab initio study of (TMTTF)_{2}PF_{6} under pressure: Implications for the unified phase diagram by Miho Itoi, Kazuyoshi Yoshimi, Hanming Ma, Takahiro Misawa, Takao Tsumuraya, Dilip Bhoi, Tokutaro Komatsu, Hatsumi Mori, Yoshiya Uwatoko, Hitoshi Seo

“…We fully resolve the crystal structure by single crystal x-ray diffraction measurements using a diamond anvil cell up to 8 GPa, and based on the structural data, we perform first-principles density-functional theory calculations and derive the ab initio extended Hubbard-type Hamiltonians. …”
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Resource-saving inter-row cultivator by N. E. Rudenko, I. A. Nosov, S. D. Kayvanov, D. A. Petukhov

“…The ploughshare performs the copying functions therefore the additional copying wheels are not required. …”
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